Methanol-based fixation is superior to buffered formalin for next-generation sequencing of DNA from clinical cancer samples

Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

(2015) Adam D Ewing et al.   NATURE METHODS

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue

(2015) Danielle Mercatante Carrick et al.   PLoS One

Dramatic reduction of sequence artefacts from DNA isolated from formalin-fixed cancer biopsies by treatment with uracil-DNA glycosylase.

(2015) Hongdo Do et al.   Oncotarget

Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing

(2014) Stephen Q Wong et al.   BMC Medical Genomics

TP53 Mutations in Human Cancer: Database Reassessment and Prospects for the Next Decade

(2014) Bernard Leroy et al.   HUMAN MUTATION

Tissue fixation and the effect of molecular fixatives on downstream staining procedures

(2014) William J. Howat et al.   METHODS

Next-Generation Sequencing of RNA and DNA Isolated from Paired Fresh-Frozen and Formalin-Fixed Paraffin-Embedded Samples of Human Cancer and Normal Tissue

(2014) Jakob Hedegaard et al.   PLoS One

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Molecular genetic testing and the future of clinical genomics

(2013) Sara Huston Katsanis et al.   NATURE REVIEWS GENETICS

Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

(2012) T. Forshew et al.   Science Translational Medicine

Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

(2011) Martin Kerick et al.   BMC Medical Genomics

Nucleic acid quantity and quality from paraffin blocks: Defining optimal fixation, processing and DNA/RNA extraction techniques

(2011) Gulisa Turashvili et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

(2010) Ahmed Ashour Ahmed et al.   JOURNAL OF PATHOLOGY

High-quality genomic DNA extraction from formalin-fixed and paraffin-embedded samples deparaffinized using mineral oil

(2009) Jianghai Lin et al.   ANALYTICAL BIOCHEMISTRY

Investigating fixative-induced changes in RNA quality and utility by microarray analysis

(2007) Melissa L. Cox et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY