Article
Endocrinology & Metabolism
Atieh Amouzegar, Samaneh Asgari, Fereidoun Azizi, Amir Abbas Momenan, Mohammadreza Bozorgmanesh, Farzad Hadaegh
Summary: The study found a significant gender difference in the association between metabolic syndrome and the risk of fracture. Central adiposity in women increased the risk of hospitalized fracture, while high fasting plasma glucose in men may decrease the risk.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Cardiac & Cardiovascular Systems
Soroush Masrouri, Seyyed Saeed Moazzeni, Neda Cheraghloo, Fereidoun Azizi, Farzad Hadaegh
Summary: The impact of different definitions of metabolic syndrome (MetS) on the risk of sudden cardiac death (SCD) in the Iranian population was evaluated. MetS, except when defined with ATP III criteria, is a marker for identifying individuals at higher risk for SCD, but not independent of its components.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Endocrinology & Metabolism
Mahbanoo Farhadi-Azar, Samira Behboudi-Gandevani, Maryam Rahmati, Fatemeh Mahboobifard, Ensi Khalili Pouya, Fahimeh Ramezani Tehrani, Fereidoun Azizi
Summary: The aim of this study was to evaluate the prevalence of polycystic ovary syndrome (PCOS) and its cardio-metabolic features in Iranian women. It was found that PCOS, especially phenotypes with androgen excess, are common in this population. These patients exhibited worse lipid profiles and higher rates of metabolic syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Firoozeh Hosseini-Esfahani, Behnaz Alafchi, Zahra Cheraghi, Amin Doosti-Irani, Parvin Mirmiran, Davood Khalili, Fereidoun Azizi
Summary: A study conducted in Tehran, Iran on MetS found that the incidence rate of MetS was significantly higher in men than in women. The most important determinants of MetS included history of diabetes, high BMI, older age, male gender, and low dietary monounsaturated fatty acid intake.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2021)
Article
Medicine, General & Internal
Marzieh Rostami Dovom, Maryam Rahmati, Saber Amanollahi Soudmand, Pardis Ziaeefar, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: This study aimed to investigate the association between kidney stones and polycystic ovarian syndrome (PCOS). The prevalence of kidney stones was found to be significantly higher in women with PCOS compared to healthy controls. Women with PCOS, particularly those with menstrual irregularities and polycystic ovarian morphology changes, were found to be at a higher risk for kidney stones.
Article
Health Care Sciences & Services
Leila Cheraghi, Parisa Amiri, Golnaz Vahedi-Notash, Sara Jalali-Farahani, Davood Khalili, Fereidoun Azizi
Summary: Different factors such as smoking, marital status, employment status, physical activity level, education, health conditions, and interventions were found to be associated with response rates in the Tehran Lipid and Glucose Study. Strategies for recruitment should target these factors to improve participant follow-up in longitudinal studies.
BMC MEDICAL RESEARCH METHODOLOGY
(2021)
Article
Oncology
Tao Thi Tran, Madhawa Gunathilake, Jeonghee Lee, Jeongseon Kim
Summary: This study found that metabolic syndrome is a risk factor for colorectal cancer, with elevated blood pressure and high fasting glucose levels also being associated with an increased risk of CRC.
Article
Endocrinology & Metabolism
Jia Y. Wan, Deborah Goodman, Sukh Makhnoon, Trina M. Norden-Krichmar, Baolin Wu, Karen L. Edwards
Summary: The study evaluated clustering of metabolic syndrome (MetS) components in individuals and families across different ancestry groups. The results showed that the prevalence of different combinations of MetS components varied among different ancestry groups. The study concluded that understanding the heterogeneity in MetS clustering could help reduce health disparities.
Review
Gastroenterology & Hepatology
Bo Lu, Jia-Ming Qian, Jing-Nan Li
Summary: Metabolic syndrome increases the risk of all-cause and colorectal cancer (CRC)-specific mortality in patients with CRC, and the risk of CRC-specific mortality increases with the number of metabolic risk factors.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Environmental Sciences
Liping Lu, Yuexia Li, Cheng Chen, Yijia Zhang, Wenzhi Guo, Shuijun Zhang, Ka Kahe
Summary: This meta-analysis reveals an association between Cd exposure and risk of MetS among Asian populations, primarily due to Cd's association with dyslipidemia.
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Ji-Eun Kim, Jin-Sun Kim, Min-Jee Jo, Eunjung Cho, Shin-Young Ahn, Young-Joo Kwon, Gang-Jee Ko
Summary: This review summarizes the role of adipokines in the development of metabolic syndrome, with a focus on glucose homeostasis and lipid metabolism.
Article
Medical Laboratory Technology
Mariel Garcia-Chagollan, Susana Elizabeth Hernandez-Martinez, Alma Elizabeth Rojas-Romero, Jose Francisco Munoz-Valle, Ramon Sigala-Arellano, Sergio Cerpa-Cruz, Jose Javier Morales-Nunez, Jose Alvaro Lomeli-Nieto, Gabriela Macedo Ojeda, Jorge Hernandez-Bello
Summary: The prevalence of Metabolic Syndrome (MetS) in rheumatoid arthritis (RA) patients from western Mexico is not significantly higher than controls. However, in RA patients with MetS, some inflammatory markers are related to MetS components.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2021)
Article
Endocrinology & Metabolism
Golaleh Asghari, Mitra Hasheminia, Abolfazl Heidari, Parvin Mirmiran, Kamran Guity, Mohammad Karim Shahrzad, Fereidoun Azizi, Farzad Hadaegh
Summary: The study found that adolescence MetS and certain combinations of MetS components are associated with early adulthood T2DM. Particularly, female adolescents and those with a family history of T2DM have a higher risk of developing T2DM.
DIABETOLOGY & METABOLIC SYNDROME
(2021)
Review
Food Science & Technology
Xue Li, Binbin Nian, Ruizhi Li, Xinyu Cao, Yanjun Liu, Yuanfa Liu, Yong-Jiang Xu
Summary: This article conducted a meta-analysis to assess the effects of fasting on patients with metabolic syndrome (MS). The results showed that fasting significantly reduced body weight, BMI, body fat percentage, insulin level, and HOMA-IR in patients with MS, while having no effect on glucose, blood pressure, and lipids profile.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Review
Food Science & Technology
Tuoping Li, Siyu Fu, Xin Huang, Xiushan Zhang, Yanmin Cui, Zuoyi Zhang, Yue Ma, Xuan Zhang, Qianhui Yu, Shuning Yang, Suhong Li
Summary: This paper summarizes the functional properties of hawthorn compounds and explores their potential applications in functional foods, providing useful insights for the development and utilization of hawthorn.
JOURNAL OF FUNCTIONAL FOODS
(2022)
Review
Endocrinology & Metabolism
A. Amouzegar, E. N. Pearce, L. Mehran, J. Lazarus, M. Takyar, F. Azizi
Summary: Studies suggest that maternal thyroid autoimmunity may have adverse effects on the neuropsychological and intellectual development of offspring, however, results are inconsistent. Variations in the tools and measurements used to assess neurodevelopment or IQ across studies may contribute to the lack of consensus in findings.
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
(2022)
Article
Psychology, Developmental
Sara Jalali-Farahani, Parisa Amiri, Fariba Zarani, Fereidoun Azizi
Summary: This study used qualitative methods to explore the perceptions of Iranian adolescents regarding their bodies, focusing on the psychological aspects that contribute to their body image perceptions. The findings revealed various beliefs, body evaluations, emotions, and behaviors among the participants.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Medicine, Research & Experimental
Fatemeh Mahboobifard, Maryam Rahmati, Atrin Niknam, Ehsan Rojhani, Amir Abbas Momenan, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: This study explored the impact of Polycystic Ovary Syndrome (PCOS) on the risk of developing cardiovascular disease (CVD), and found that PCOS status did not increase the risk of silent coronary artery disease (CAD). However, women with a history of silent CAD had a higher incidence of CVD events. PCOS status independently reduced the incidence of CVD, regardless of silent CAD or traditional risk factors.
ARCHIVES OF MEDICAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Amirreza Hadaegh, Samaneh Akbarpour, Maryam Tohidi, Niloofar Barzegar, Somayeh Hosseinpour-Niazi, Fereidoun Azizi, Farzad Hadaegh
Summary: The study found significant associations between TAG, TAG/HDL-cholesterol, and TC/HDL-cholesterol and a higher risk of incident hypertension, while HDL-cholesterol was associated with a lower risk. These associations remained independent of baseline blood pressure categories and other factors, suggesting their potential role in predicting hypertension.
BRITISH JOURNAL OF NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Marzieh Saei Ghare Naz, Ali Sheidaei, Ali Aflatounian, Fereidoun Azizi, Fahimeh Ramezani Tehrani
Summary: This study aimed to investigate whether adding adverse pregnancy outcomes (APOs) to the Framingham risk score improves the prediction of cardiovascular disease (CVD) events in women. The results showed that adding APOs can improve the accurate risk estimation of CVD beyond established risk factors, and women with a history of multiple APOs are at higher risk of experiencing CVD events.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2022)
Article
Nutrition & Dietetics
Parvin Mirmiran, Hossein Farhadnejad, Farshad Teymoori, Karim Parastouei, Fereidoun Azizi
Summary: This study investigates the combined effects of recognized lifestyle factors, expressed as a healthy lifestyle score, on the risk of metabolic syndrome in Tehranian adults. The findings highlight the importance of adherence to modifiable healthy lifestyle factors in reducing the risk of metabolic syndrome.
NUTRITION BULLETIN
(2022)
Review
Endocrinology & Metabolism
Nazanin Moslehi, Fatemeh Rahimi Sakak, Farshad Teymoori, Fahimeh Ramezani Tehrani, Parvin Mirmiran, Fereidoun Azizi
Summary: This study reviewed 49 publications on the association between nutrition and gestational diabetes mellitus (GDM) in Iranian women. The pooled analyses showed that GDM women had lower serum vitamin D levels and higher serum iron, ferritin, and hemoglobin levels compared to non-GDM women. Some dietary patterns were found to be associated with the odds of GDM. Vitamin D supplementation early in pregnancy may help prevent GDM, but there is insufficient evidence to recommend a specific dietary pattern for GDM prevention in Iranian women.
JOURNAL OF DIABETES AND METABOLIC DISORDERS
(2022)
Article
Plant Sciences
Effat Ghadirzadeh-Khorzoghi, Masoomeh Jannesar, Zahra Jahanbakhshian-Davaran, Maryam Moazzam-Jazi, Abolfazl Lotfi, Ali Tajabadi Pour, Seyed Mahdi Seyedi
Summary: This study determined the progeny sex ratio in four pistachio populations using molecular markers and found a female-biased sex ratio. Under stressful conditions, the sex ratio can deviate towards males, and this deviation increases with the intensity of the stress. Females are more affected than males based on physical measurements. These findings have economic importance for introducing more tolerant pistachio gender and can be used for breeding programs and reforestation.
PLANT PHYSIOLOGY REPORTS
(2022)
Article
Genetics & Heredity
Saeideh Jafarinejad-Farsangi, Maryam Moazzam-Jazi, Zari Naderi Ghale-noie, Nahid Askari, Zahra Miri Karam, Samaneh Mollazadeh, Morteza Hadizadeh
Summary: This study combines multiple microarray studies to identify genes and pathways specific to each subtype of breast cancer. Through the analysis of differentially expressed genes (DEGs), critical genes and pathways associated with BC subtypes were identified. The results were validated using an independent breast cancer RNA-sequencing dataset, showing high concordance in specific genes related to certain subtypes.
Article
Nutrition & Dietetics
Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi
Summary: This study found that higher intake of oxalate may be associated with a slightly increased risk of incident cardiovascular disease, especially in a diet with low calcium intake.
Article
Multidisciplinary Sciences
Parvin Mirmiran, Asiyeh Sadat Zahedi, Glareh Koochakpour, Firoozeh Hosseini-Esfahani, Mahdi Akbarzadeh, Maryam S. Daneshpour, Fereidoun Azizi
Summary: This study investigated the correlation between nutrient intakes and gender in three generations of Tehranian adults. The results showed significant correlations in nutrient intakes between fathers and sons, as well as mothers and daughters. However, there were no significant correlations between parents and adult offspring. Younger offspring had higher intakes of total fat and trans-fatty acids compared to their parents.
Article
Medicine, General & Internal
M. Tohidi, N. Barzegar, M. Hasheminia, F. Azizi, F. Hadaegh
Summary: This study aimed to investigate the association between different lipid measures and long-term hospitalization-required incident fracture among Iranian men and women. The results showed a nonlinear association between non-HDL-C and LDL-C and incident fracture among Iranian women, with the second and fifth quintiles of non-HDL-C and the second quintile of LDL-C associated with about 50% lower risk of fracture.
POSTGRADUATE MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Maryam S. Daneshpour, Mahdi Akbarzadeh, Hossein Lanjanian, Bahar Sedaghati-Khayat, Kamran Guity, Sajedeh Masjoudi, Asiyeh Sadat Zahedi, Maryam Moazzam-Jazi, Leila Najd Hassan Bonab, Bita Shalbafan, Sara Asgarian, Goodarz Koli Farhood, Niloofar Javanrooh, Maryam Zarkesh, Parisa Riahi, Mohammad Reza Moghaddas, Parvaneh Arbab Dehkordi, Azar Delbarpour Ahmadi, Firoozeh Hosseini, Sara Jalali Farahani, Farzad Hadaegh, Parvin Mirmiran, Fahimeh Ramezani Tehrani, Arash Ghanbarian, Mohammad Sadegh Fallah Mahboob Pasand, Parisa Amiri, Majid Valizadeh, Farhad Hosseipanah, Maryam Tohidi, Asghar Ghasemi, Azita Zadeh-Vakili, Mohammad Piryaei, Shahram Alamdari, Davood Khalili, Amirabbas Momenan, Maryam Barzin, Sirous Zeinali, Mehdi Hedayati, Fereidoun Azizi
Summary: The Tehran cardiometabolic genetic study (TCGS) is a large population-based cohort study that conducts periodic follow-ups. Its primary goal is to identify potential targets for prevention and intervention for non-communicable diseases that may develop in mid-life and late life. This research provides an update on the study's rationale and design, summarizes its findings, and outlines the objectives for precision medicine.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Leila Najd-Hassan-Bonab, Mehdi Hedayati, Seyed Abolhassan Shahzadeh Fazeli, Maryam S. Daneshpour
Summary: This study optimized the Tetra-ARMS PCR method for detecting APOE mutations. The optimized method showed high accuracy and sensitivity, allowing for DNA amplification without the use of hazardous reagents. It can be performed even in low-tech laboratories.