Article
Multidisciplinary Sciences
Bianca Perera, Chris Barton, Christian Osadnik
Summary: Acute exacerbations of COPD (AECOPDs) are a major cause of preventable hospital admissions in Australia. The immediate period following an exacerbation is critical for intervention to prevent recurrence. This study found that general practitioners (GPs) in Australia lack familiarity with COPD guidelines and face challenges in obtaining necessary information from hospital discharge summaries. Prioritization of referrals to rehabilitation and evaluation of spirometry and oxygen therapy needs improvement.
Article
Cardiac & Cardiovascular Systems
Yoshiharu Kinugasa, Masakazu Saitoh, Toshimi Ikegame, Aoi Ikarashi, Kazushige Kadota, Kentaro Kamiya, Shun Kohsaka, Atsushi Mizuno, Isao Miyajima, Eisaku Nakane, Azusa Nei, Tatsuhiro Shibata, Hiroyuki Yokoyama, Sei Yumikura, Dai Yumino, Noboru Watanabe, Mitsuaki Isobe
Summary: This study clarified the current status and issues of community collaboration in heart failure management in Japan through a nationwide survey. Hospital cardiologists prioritize medical intervention while general practitioners prioritize supporting daily living, leading to differences in priorities. Challenges identified include lack of information sharing, limited communication opportunities between hospitals and community staff, and underdeveloped consultation systems for home care transition.
CIRCULATION JOURNAL
(2021)
Article
Infectious Diseases
D. T. P. Buis, J. M. Prins, L. Betica-Radic, M. G. J. de Boer, M. Ekkelenkamp, D. Kofteridis, N. Peiffer-Smadja, J. Schouten, N. Spernovasilis, P. Tattevin, J. ten Oever, K. C. E. Sigaloff
Summary: This study aimed to investigate clinical practice variation and knowledge gaps in antibiotic treatment of Staphylococcus aureus bacteraemia (SAB) through a web-based survey among infectious disease specialists, clinical microbiologists, and internists in five European countries.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
(2022)
Article
Otorhinolaryngology
A. Loth, C. Vazzana, M. Leinung, D. Guderian, C. Issing, U. Baumann, T. Stoever
Summary: This study investigated the availability of clinical practice guidelines (CPGs) and registries related to cochlear implants (CI) in European countries and found limitations in terms of quantity. While most European countries already have CPGs for CI, the availability of CI registries is still relatively low. It indicates that there is currently no European-wide consensus on CPGs and registries for CI.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2022)
Article
Psychiatry
Marco Lehmann, Nadine Janis Pohontsch, Thomas Zimmermann, Martin Scherer, Bernd Loewe
Summary: The study estimated that 7.7% of patients in general practice fulfill the diagnostic criteria for Somatic Symptom Disorder (SSD), indicating a high clinical relevance of the clinical symptoms of SSD in general practice.
Article
Geriatrics & Gerontology
Katharina Tabea Jungo, Sophie Mantelli, Zsofia Rozsnyai, Aristea Missiou, Biljana Gerasimovska Kitanovska, Birgitta Weltermann, Christian Mallen, Claire Collins, Daiana Bonfim, Donata Kurpas, Ferdinando Petrazzuoli, Gindrovel Dumitra, Hans Thulesius, Heidrun Lingner, Kasper Lorenz Johansen, Katharine Wallis, Kathryn Hoffmann, Lieve Peremans, Liina Pilv, Marija Petek Ster, Markus Bleckwenn, Martin Sattler, Milly van der Ploeg, Peter Torzsa, Petra Bomberova Kanska, Shlomo Vinker, Radost Assenova, Raquel Gomez Bravo, Rita P. A. Viegas, Rosy Tsopra, Sanda Kreitmayer Pestic, Sandra Gintere, Tuomas H. Koskela, Vanja Lazic, Victoria Tkachenko, Emily Reeve, Clare Luymes, Rosalinde K. E. Poortvliet, Nicolas Rodondi, Jacobijn Gussekloo, Sven Streit
Summary: The majority of GPs in this study were willing to deprescribe one or more medications in oldest-old multimorbid patients with polypharmacy. Willingness was higher in patients with increased dependency in ADL and lower in patients with CVD.
Article
Computer Science, Cybernetics
David Fraile Navarro, A. Baki Kocaballi, Mark Dras, Shlomo Berkovsky
Summary: General Practitioners, the main users and curators of textual electronic health records, need technologies that support record access and administration. Recent advancements in natural language processing have led to the development of clinical systems that automate some record-keeping tasks. However, it is unclear which tasks would benefit clinicians the most, what features the automation should have, and how clinicians will interact with it.
ACM TRANSACTIONS ON COMPUTER-HUMAN INTERACTION
(2023)
Article
Food Science & Technology
Pierrine Didier, Christophe Nguyen-The, Lydia Martens, Mike Foden, Loredana Dumitrascu, Augustin Octavian Mihalache, Anca Ioana Nicolau, Silje Elisabeth Skuland, Monica Truninger, Luis Junqueira, Isabelle Maitre
Summary: A study on hand washing practices during raw chicken handling in five European countries revealed differences in habits and attitudes towards hand hygiene, with some participants not using soap after touching raw chicken. The research showed that only a third of participants washed their hands with soap after handling raw chicken, with the majority in Norway and the UK, few in France and Portugal, and none in Romania. Barriers to proper hand washing were mainly observed in Romania, where participants did not always perceive touching raw chicken as a risky behavior.
Article
Endocrinology & Metabolism
Stephanie Dranebois, Marie Laure Lalanne-Mistrih, Mathieu Nacher, Liliane Thelusme, Sandra Deungoue, Magalie Demar, Maryvonne Dueymes, Kinan Drak Alsibai, Nadia Sabbah
Summary: GPs in French Guiana face obstacles in prescribing physical activity for patients with type 2 diabetes. Improving GP training, developing appropriate structures for physical activity, and promoting collaboration among stakeholders are important measures to address these barriers.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Health Care Sciences & Services
Daniel Caesar Torp, Annelli Sandbaek, Thim Praetorius
Summary: This study examined general practitioners' technology acceptance of video consultations for managing type 2 diabetes in general practice. The results showed that perceived usefulness was the primary driver of general practitioners' positive attitude towards video consultations.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Education & Educational Research
Manuel Villarreal, Petra Hanson, Amy Clarke, Majid Khan, Jeremy Dale
Summary: The study found that incorporating mindful practice in general practice vocational training is feasible and beneficial for participants' psychological wellbeing. Further research is needed to explore ways to increase participation and course completion, sustainability of effects, and wider applicability of this approach.
BMC MEDICAL EDUCATION
(2021)
Article
Public, Environmental & Occupational Health
Fabia Teixeira, Edmond Li, Liliana Laranjo, Claire Collins, Greg Irving, Maria Jose Fernandez, Josip Car, Mehmet Ungan, Davorina Petek, Robert Hoffman, Azeem Majeed, Katarzyna Nessler, Heidrun Lingner, Geronimo Jimenez, Ara Darzi, Cristina Jacome, Ana Luisa Neves
Summary: This study assessed the global digital maturity in General Practice and its association with participants' demographic characteristics, practice characteristics, and features of Electronic Health Records (EHRs) use. The study found positive associations between digital maturity and male gender, longer periods of EHRs use, and higher frequencies of access to EHRs. Practicing in a rural setting was negatively associated with digital maturity. The study provides guidance for policymakers to develop more effective interventions to hasten the digital transformation of General Practice.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Economics
Dovile Stumbriene, Rimantas Zelvys, Julius Zilinskas, Rita Dukynaite, Audrone Jakaitiene
Summary: This paper proposes a conceptual framework for education systems based on the concepts of efficiency and effectiveness from the perspective of inclusion and fairness. It applies this framework to 26 European countries and demonstrates its applicability. The results show that European countries have differences in ensuring inclusion and fairness within their education systems and between key stages. The paper also emphasizes the need to interpret economic categories such as effectiveness and efficiency in education considering the peculiarities of national education systems.
SOCIO-ECONOMIC PLANNING SCIENCES
(2022)
Article
Education & Educational Research
Charlotte G. M. van Sassen, Pieter J. van den Berg, Silvia Mamede, Lilian Knol, Manon P. Eikens-Jansen, Walter W. van den Broek, Patrick J. E. Bindels, Laura Zwaan
Summary: The study aimed to identify and prioritize educational content from a malpractice claims database to enhance clinical reasoning education in General Practitioners' training. The prioritized conditions included complex common, complex rare, and more straightforward common conditions, often exhibiting atypical presentations or complex contextual factors.
ADVANCES IN HEALTH SCIENCES EDUCATION
(2023)
Review
Medicine, General & Internal
Claire M. Lawley, Juan Pablo Kaski
Summary: Hypertrophic cardiomyopathy (HCM) is a significant cause of illness and death in children. Most cases are caused by gene variants in the cardiac sarcomere components, inherited as an autosomal dominant trait. Recent studies have shown that phenotypic expression of HCM can occur in young children, highlighting the need for clinical screening and genetic testing in pediatric relatives. The multidisciplinary care of HCM-affected children and families relies on genomics.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Genetics & Heredity
Katerina S. Kucera, Beth Lincoln Boyea, Brooke Migliore, Sarah Nelson Potter, Veronica R. Robles, Oksana Kutsa, Heidi Cope, Katherine C. Okoniewski, Anne Wheeler, Catherine W. Rehder, Edward C. Smith, Holly L. Peay
Summary: Screening for elevated CK-MM levels in dried blood spots is a feasible method to identify newborns with DMD. Including specific cutoffs, repeat testing, and genetic sequencing can improve the accuracy and sensitivity of screening.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Madeline Currey, Ilana Solomon, Sarah Mcgraw, Jenny Shen, Francisco Munoz, Ernesto Sosa, Vanessa Puello-Lozano, Sam Wing, Lisa Lopez, Michelle Afkhami, Janine Lobello, Szabolcs Szelinger, Stacy W. Gray
Summary: This study conducted qualitative interviews with cancer patients and providers to identify gaps in clinical care and propose care delivery solutions for the return of secondary germline findings. The responses of patients varied depending on the amount of pre-test counseling they received, and providers identified insufficient clinic time as a major barrier to pretest education. Online support tools and standardized pre-test education models were favored by providers. There were differing perspectives on how pre-test education should be integrated into clinical workflows, but agreement on the inclusion of differences between somatic and germline testing, likelihood of medically actionable findings, and the possibility of being referred to a genetics provider.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Kiely N. James, Shimul Chowdhury, Yan Ding, Sergey Batalov, Kelly Watkins, Yong Hyun Kwon, Lucitia Van Der Kraan, Katarzyna Ellsworth, Stephen F. Kingsmore, Lucia Guidugli
Summary: This study used genome sequencing to detect a wide range of copy-number variants (CNVs) and other non-single nucleotide variant/indel variant types. These genetic alterations accounted for 15.8% of reported variants, with deletions being the most common type. The study also found that additional genetic tests were ordered in some cases, but failed to report the variants detected by genome sequencing.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Asem Berkalieva, Nicole R. Kelly, Ashley Fisher, Samuel F. Hohmann, Monisha Sebastin, Miranda Di Biase, Katherine E. Bonini, Priya Marathe, Jacqueline A. Odgis, Sabrina A. Suckiel, Michelle A. Ramos, Rosamond Rhodes, Noura S. Abul-Husn, John M. Greally, Carol R. Horowitz, Melissa P. Wasserstein, Eimear E. Kenny, Bruce D. Gelb, Bart S. Ferket
Summary: The study aims to understand the effects of returning diagnostic sequencing results on clinical actions and economic outcomes for pediatric patients with suspected genetic disorders. The results showed that patients with positive findings were more likely to receive specialist consultation, but there were no significant increases in overall physician services and costs. More large-scale studies are needed to confirm these findings.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Kirstine Stochholm, Camilla Holmgard, Shanlee M. Davis, Claus H. Gravholt, Agnethe Berglund
Summary: This study assessed the incidence, prevalence, and age at diagnosis of individuals with 45,X/46,XY mosaicism and described the associated mortality pattern. The study found an increasing incidence of 45,X/46,XY mosaicism in males and a stable incidence in females. Males were diagnosed at an older age than females. Additionally, 45,X/46,XY mosaicism was associated with increased all-cause mortality.
GENETICS IN MEDICINE
(2024)
Article
Genetics & Heredity
Yunjia Chen, Ender Karaca, Nathaniel H. Robin, Dana Goodloe, Ali Al-Beshri, S. Joy Dean, Anna C. E. Hurst, Andrew J. Carroll, Fady M. Mikhail
Summary: This study confirms the association between DLG2 intragenic deletions and neurodevelopmental disorders, supports the haploinsufficiency of the DLG2 gene, and suggests a potential association between these deletions and congenital anomalies and dysmorphism.
GENETICS IN MEDICINE
(2024)
