Article
Agronomy
Victoria E. Edematie, Christian Fatokun, Ousmane Boukar, Victor O. Adetimirin, P. Lava Kumar
Summary: This study investigated the gene effects involved in the inheritance of pod length and yield-related traits in cowpea crosses with yard-long beans. Different gene effects and magnitudes were found between the crosses, with digenic epistatic gene effects being detected in some traits. Pod length showed significant correlation with major yield components, indicating the potential for improving cowpea seed yield through selection for long pods.
Article
Multidisciplinary Sciences
Kyle R. Fowler, Fredrick Leon, Alexander D. Johnson
Summary: Cells regulate gene expression through the binding of transcription regulators to cis-regulatory sequences. Pair-wise cooperativity between regulators is common and allows for complex gene regulation. This study investigates the mechanisms and constraints of cooperative interactions between ancient transcriptional regulators. The findings provide insights into the evolution of gene regulation and the importance of epistasis in protein-protein interactions.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Genetics & Heredity
L. E. Puhl, J. Crossa, S. Munilla, P. Perez-Rodriguez, R. J. C. Cantet
Summary: In this study, hierarchical Bayesian models were used to analyze the additive variance of SHW and SHWD, showing that the additive variance of grain yield comes from different breed categories and segregation variance explains a significant proportion of phenotypic variance between populations of different species.
Article
Genetics & Heredity
Heena Attri, Tuhina Dey, Bikram Singh, Amardeep Kour
Summary: This study focused on deciphering the genetics and inheritance of traits/genes influencing grain yield, suggesting that selection for grain yield and its components should be delayed to later generations of breeding.
JOURNAL OF GENETICS
(2021)
Article
Agronomy
Raman Selvakumar, Dalasanuru Chandregowda Manjunathagowda, Pritam Kalia, Ranjeet Sharad Raje
Summary: Genetic analysis of carrot economic traits revealed the presence of various gene actions, including additive, dominance, additive x additive, additive x dominance, and dominance x dominance. Understanding these gene interactions and effects can help in enhancing genetic advantages and exploiting heterosis, ultimately guiding breeding methods and selection of segregates with desirable economic traits.
GENETIC RESOURCES AND CROP EVOLUTION
(2021)
Article
Chemistry, Multidisciplinary
Adrian Cyplik, Aleksandra Sobiech, Agnieszka Tomkowiak, Jan Bocianowski
Summary: This paper presents an estimation of the parameters connected with the additive effect, aa epistatic effect, and aaa interaction gene effect for nine quantitative traits of maize inbred lines. The study found significant two-way and three-way interactions in most cases, which had a considerable impact on the phenotype. Neglecting higher-order interactions may result in a substantial underestimation of additive QTL effects.
APPLIED SCIENCES-BASEL
(2022)
Article
Plant Sciences
Greg M. Walter, James Clark, Delia Terranova, Salvatore Cozzolino, Antonia Cristaudo, Simon J. Hiscock, Jon Bridle
Summary: Rapid environmental change forces populations into environments where plasticity cannot maintain fitness. According to evolutionary theory, genetic variation in fitness should increase when populations are exposed to novel environments and be associated with genetic differences in plasticity. This study transplanted clones of a Sicilian daisy within and outside its native range, and found that genetic variation in fitness increased in the novel environment and was correlated with plasticity in leaf traits and gene expression.
Article
Multidisciplinary Sciences
Javier Santos-Moreno, Eve Tasiudi, Hadiastri Kusumawardhani, Joerg Stelling, Yolanda Schaerli
Summary: Genotype networks are sets of genotypes connected by small mutational changes that share the same phenotype. The authors combine construction of over 20 synthetic gene regulatory networks with mathematical modeling to exemplify how gene regulatory networks provide robustness in face of mutations while enabling transitions to innovative phenotypes.
NATURE COMMUNICATIONS
(2023)
Article
Forestry
J. J. Ilska, D. J. Tolhurst, H. Tumas, J. P. Maclean, J. Cottrell, S. J. Lee, J. Mackay, J. A. Woolliams
Summary: Many genetic models assume all genetic variation is additive due to lack of data. This research estimates the proportions of additive and non-additive genetic variation in Sitka spruce for height, bud burst, and pilodyn penetration depth. The results show differences in the contribution of additive variation across age groups and locations.
TREE GENETICS & GENOMES
(2023)
Article
Biology
Zhen Jia, Peng Gao, Feifan Yin, Teagen D. D. Quilichini, Huajin Sheng, Jingpu Song, Hui Yang, Jie Gao, Ting Chen, Bo Yang, Leon V. V. Kochian, Jitao Zou, Nii Patterson, Qingyong Yang, C. Stewart Gillmor, Raju Datla, Qiang Li, Daoquan Xiang
Summary: This study investigates the effects of gene expression on the development of hybrid seeds by analyzing the transcriptomes of polyploid grains. The results show that hybridization between species with different ploidy levels has broad impacts on gene expression, including changes in alternative splicing events and enhanced protein synthesis. The study also identifies imprinted genes that play important roles in early embryonic development.
COMMUNICATIONS BIOLOGY
(2022)
Article
Plant Sciences
Maria Jose Gonzalo, Luciano Carlos da Maia, Inmaculada Najera, Carlos Baixauli, Giovanni Giuliano, Paola Ferrante, Antonio Granell, Maria Jose Asins, Antonio Jose Monforte
Summary: This study investigated the genetic control of reproductive traits under heat stress conditions in two populations of inbred lines derived from crosses between two S. pimpinellifolium accessions and two tomato cultivars. The results identified the impact of heat stress on reproductive traits, detected QTL clusters, and revealed several epistatic interactions in one population.
Article
Multidisciplinary Sciences
Kyle J. Card, Misty D. Thomas, Joseph L. Graves, Jeffrey E. Barrick, Richard E. Lenski
Summary: Antibiotic resistance is a growing health concern, with epistatic interactions between mutations complicating the ability to predict evolution. Differences in genetic backgrounds can lead to idiosyncratic responses in the evolvability of resistance, with lineages founded by different genotypes taking parallel or divergent mutational paths. Historical contingency can alter both genotypic and phenotypic pathways to antibiotic resistance, as evidenced by differences in mutation patterns among different genetic starting points.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Tiffany N. Batarseh, Sarah N. Batarseh, Alejandra Rodriguez-Verdugo, Brandon S. Gaut
Summary: Evolution is influenced by historical contingency, however, the underlying processes and dynamics governing this contingency are not well understood. In this study, a two-phase evolution experiment was conducted to investigate the features of contingency. The first phase involved the evolution of Escherichia coli clones under stressful conditions, with two adaptive pathways identified: mutations in rpoB or rho genes. The second phase explored how genetic divergence and adaptive pathway affected evolutionary outcomes. The results showed that phenotype and genotype were contingent on founder genotypes and pathways, suggesting that evolution is heavily influenced by genetic history and idiosyncratic epistatic interactions.
MOLECULAR BIOLOGY AND EVOLUTION
(2023)
Article
Genetics & Heredity
Merve Kasap, Donard S. Dwyer
Summary: Schizophrenia is a highly heritable polygenic psychiatric disorder. Characterization of its genetic architecture may help understand the burden of risk variants and their impact on susceptibility. Using a mathematical model, this study found that schizophrenia risk genes have higher interactions with other genes, potentially amplifying the effects of risk variants. The model also suggests that the number of risk alleles required to reach susceptibility threshold is influenced by multiple factors.
Article
Agriculture, Dairy & Animal Science
Valentina Bonfatti, Roberta Rostellato, Paolo Carnier
Summary: The response to genetic selection in animal populations depends on both additive and nonadditive effects. Neglecting nonadditive effects may lead to an overestimation of the genetic progress achievable. Dominance effects influence the prediction of genetic progress in heavy pigs, and neglecting them can result in an overestimation of additive genetic variance, but including litter effects in genetic evaluations can prevent this without affecting animal ranking or the accuracy of breeding values.
Article
Biodiversity Conservation
Mikhail Ozerov, Tauno Juergenstein, Tutku Aykanat, Anti Vasemaegi
CONSERVATION BIOLOGY
(2015)
Review
Ecology
M. Y. Ozerov, M. Himberg, T. Aykanat, D. S. Sendek, H. Hagerstrand, A. Verliin, T. Krause, J. Olsson, C. R. Primmer, A. Vasemagi
JOURNAL OF EVOLUTIONARY BIOLOGY
(2015)
Article
Fisheries
T. Aykanat, M. Lindqvist, V. L. Pritchard, C. R. Primmer
JOURNAL OF FISH BIOLOGY
(2016)
Article
Ecology
Yann Czorlich, Tutku Aykanat, Jaakko Erkinaro, Panu Orell, Craig Robert Primmer
NATURE ECOLOGY & EVOLUTION
(2018)
Article
Ecology
Tutku Aykanat, Mikhail Ozerov, Juha-Pekka Vaha, Panu Orell, Eero Niemela, Jaakko Erkinaro, Craig R. Primmer
JOURNAL OF EVOLUTIONARY BIOLOGY
(2019)
Article
Multidisciplinary Sciences
Kenyon B. Mobley, Hanna Granroth-Wilding, Mikko Ellmen, Juha-Pekka Vaha, Tutku Aykanat, Susan E. Johnston, Panu Orell, Jaakko Erkinaro, Craig R. Primmer
Article
Ecology
Ronan James O'Sullivan, Tutku Aykanat, Susan E. Johnston, Adam Kane, Russell Poole, Ger Rogan, Paulo A. Prodohl, Craig R. Primmer, Philip McGinnity, Thomas Eric Reed
ECOLOGY AND EVOLUTION
(2019)
Article
Genetics & Heredity
Johanna Kurko, Paul V. Debes, Andrew H. House, Tutku Aykanat, Jaakko Erkinaro, Craig R. Primmer
G3-GENES GENOMES GENETICS
(2020)
Article
Ecology
Tutku Aykanat, Martin Rasmussen, Mikhail Ozerov, Eero Niemela, Lars Paulin, Juha-Pekka Vaha, Kjetil Hindar, Vidar Wennevik, Torstein Pedersen, Martin-A. Svenning, Craig R. Primmer
JOURNAL OF ANIMAL ECOLOGY
(2020)
Article
Biology
Ronan James O'Sullivan, Tutku Aykanat, Susan E. Johnston, Ger Rogan, Russell Poole, Paulo A. Prodohl, Elvira de Eyto, Craig R. Primmer, Philip McGinnity, Thomas Eric Reed
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2020)
Article
Genetics & Heredity
Jukka-Pekka Verta, Paul Vincent Debes, Nikolai Piavchenko, Annukka Ruokolainen, Outi Ovaskainen, Jacqueline Emmanuel Moustakas-Verho, Seija Tillanen, Noora Parre, Tutku Aykanat, Jaakko Erkinaro, Craig Robert Primmer
Article
Biochemistry & Molecular Biology
Marion Sinclair-Waters, Nikolai Piavchenko, Annukka Ruokolainen, Tutku Aykanat, Jaakko Erkinaro, Craig R. Primmer
Summary: Efforts to understand the genetic basis of phenotypic variation in molecular ecology are increasing. In Atlantic salmon, a study utilizing natural recombination between two candidate genes, vgll3 and akap11, found strong association between vgll3 single nucleotide polymorphisms (SNPs) and early maturation, while little or no association was found with akap11 SNPs. This suggests vgll3 as the primary candidate gene influencing early maturation.
Article
Biology
Jenni M. Prokkola, Eirik R. Asheim, Sergey Morozov, Paul Bangura, Jaakko Erkinaro, Annukka Ruokolainen, Craig R. Primmer, Tutku Aykanat
Summary: This study reveals the impact of genetic and phenotypic structure on life-history variation, using Atlantic salmon as an ideal model. The research found the association between early maturation genotype with higher metabolic rates and aerobic scope, as well as the physiological epistasis between late maturation genotypes.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2022)
Article
Ecology
Eirik R. Asheim, Jenni M. Prokkola, Sergey Morozov, Tutku Aykanat, Craig R. Primmer
Summary: The maturation timing of Atlantic salmon is influenced by the vgll3 gene, but the effect of vgll3 genotype on metabolic rate in juvenile salmon is minimal. This suggests that body condition and maturation are not strongly related to maintenance energy expenditure in this life stage.
ECOLOGY AND EVOLUTION
(2022)
Article
Multidisciplinary Sciences
Y. Czorlich, T. Aykanat, J. Erkinaro, P. Orell, C. R. Primmer
Summary: This study identifies the drivers of evolution towards early maturation in Atlantic salmon through two types of fisheries-induced evolution (indirect and direct effects), demonstrating the potential impact of aquaculture on wild salmon populations.