A Two-Platform Design for Next Generation Genome-Wide Association Studies

Next-generation association studies for complex traits

(2011) Eleftheria Zeggini   NATURE GENETICS

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

(2011) Hilma Holm et al.   NATURE GENETICS

Quantifying the Underestimation of Relative Risks from Genome-Wide Association Studies

(2011) Chris Spencer et al.   PLoS Genetics

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

(2010) Yun Li et al.   GENETIC EPIDEMIOLOGY

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Estimation of effect size distribution from genome-wide association studies and implications for future discoveries

(2010) Ju-Hyun Park et al.   NATURE GENETICS

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Utilizing Genotype Imputation for the Augmentation of Sequence Data

(2010) Brooke L. Fridley et al.   PLoS One

Deep resequencing reveals excess rare recent variants consistent with explosive population growth

(2010) Alex Coventry et al.   Nature Communications

Genotype Imputation

(2009) Yun Li et al.   Annual Review of Genomics and Human Genetics

Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies

(2009) Ke Hao et al.   BMC GENETICS

Genome-wide association studies in cancer--current and future directions

(2009) C. C. Chung et al.   CARCINOGENESIS

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Sequencing technologies — the next generation

(2009) Michael L. Metzker   NATURE REVIEWS GENETICS

Discovery of Rare Variants via Sequencing: Implications for the Design of Complex Trait Association Studies

(2009) Bingshan Li et al.   PLoS Genetics

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Evaluating the Effects of Imputation on the Power, Coverage, and Cost Efficiency of Genome-wide SNP Platforms

(2008) Carl A. Anderson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Imputation of missing genotypes: an empirical evaluation of IMPUTE

(2008) Zhenming Zhao et al.   BMC GENETICS

Multiple loci identified in a genome-wide association study of prostate cancer

(2008) Gilles Thomas et al.   NATURE GENETICS

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Analyses and Comparison of Accuracy of Different Genotype Imputation Methods

(2008) Yu-Fang Pei et al.   PLoS One