Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling

Hierarchical Modeling for Estimating Relative Risks of Rare Genetic Variants: Properties of the Pseudo-Likelihood Method

(2010) Marinela Capanu et al.   BIOMETRICS

Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women’s Health Study

(2010) Edward A. Ruiz-Narvaez et al.   BREAST CANCER RESEARCH AND TREATMENT

Evaluating Cancer Epidemiologic Risk Factors Using Multiple Primary Malignancies

(2010) Ekatherina Kuligina et al.   EPIDEMIOLOGY

Approaches for Evaluating Rare Polymorphisms in Genetic Association Studies

(2010) Qizhai Li et al.   HUMAN HEREDITY

Characterization ofBRCA1andBRCA2deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study

(2010) Åke Borg et al.   HUMAN MUTATION

Population-Based Study of the Risk of Second Primary Contralateral Breast Cancer Associated With Carrying a Mutation inBRCA1orBRCA2

(2010) Kathleen E. Malone et al.   JOURNAL OF CLINICAL ONCOLOGY

Family History, Genetic Testing, and Clinical Risk Prediction: Pooled Analysis of CHEK2*1100delC in 1,828 Bilateral Breast Cancers and 7,030 Controls

(2009) O. Fletcher et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Common vs. rare allele hypotheses for complex diseases

(2009) Nicholas J Schork et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

An evaluation of statistical approaches to rare variant analysis in genetic association studies

(2009) Andrew P. Morris et al.   GENETIC EPIDEMIOLOGY

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1)

(2009) Gilles Thomas et al.   NATURE GENETICS

Shifting Paradigm of Association Studies: Value of Rare Single-Nucleotide Polymorphisms

(2008) Ivan P. Gorlov et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Classification of rare missense substitutions, using risk surfaces, with genetic- and molecular-epidemiology applications

(2008) Sean V. Tavtigian et al.   HUMAN MUTATION

Variation of Breast Cancer Risk Among BRCA1/2 Carriers

(2008) Colin B. Begg et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Mouse embryonic stem cell–based functional assay to evaluate mutations in BRCA2

(2008) Sergey G Kuznetsov et al.   NATURE MEDICINE

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33

(2008) B. Gold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of hierarchical models for estimating relative risks of individual genetic variants: An application to a study of melanoma

(2008) Marinela Capanu et al.   STATISTICS IN MEDICINE