Population-based and family-based designs to analyze rare variants in complex diseases

Incorporating linkage information into a common disease/rare variant framework

(2011) Anthony L. Hinrichs et al.   GENETIC EPIDEMIOLOGY

Statistical analysis of rare sequence variants: an overview of collapsing methods

(2011) Carmen Dering et al.   GENETIC EPIDEMIOLOGY

Pooled Association Tests for Rare Variants in Exon-Resequencing Studies

(2010) Alkes L. Price et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Model-Based Multifactor Dimensionality Reduction for detecting epistasis in case-control data in the presence of noise

(2010) Tom Cattaert et al.   ANNALS OF HUMAN GENETICS

A Data-Adaptive Sum Test for Disease Association with Multiple Common or Rare Variants

(2010) Fang Han et al.   HUMAN HEREDITY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Statistical analysis strategies for association studies involving rare variants

(2010) Vikas Bansal et al.   NATURE REVIEWS GENETICS

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Genomewide Association Studies and Assessment of the Risk of Disease

(2010) Teri A. Manolio   NEW ENGLAND JOURNAL OF MEDICINE

Comprehensive Approach to Analyzing Rare Genetic Variants

(2010) Thomas J. Hoffmann et al.   PLoS One

An evaluation of statistical approaches to rare variant analysis in genetic association studies

(2009) Andrew P. Morris et al.   GENETIC EPIDEMIOLOGY

Univariate/Multivariate Genome-Wide Association Scans Using Data from Families and Unrelated Samples

(2009) Lei Zhang et al.   PLoS One

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

(2009) Bo Eskerod Madsen et al.   PLoS Genetics

A Unified Association Analysis Approach for Family and Unrelated Samples Correcting for Stratification

(2008) Xiaofeng Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Simple association analysis combining data from trios/sibships and unrelated controls

(2008) Yi-Hau Chen et al.   GENETIC EPIDEMIOLOGY

Personal genomes: The case of the missing heritability

(2008) Brendan Maher   NATURE

Improving strategies for detecting genetic patterns of disease susceptibility in association studies

(2008) M. L. Calle et al.   STATISTICS IN MEDICINE