Nrf2 induces fibroblast growth factor 21 in diabetic mice

Myeloid Lineage-Specific Deletion of Antioxidant System Enhances Tumor Metastasis

(2014) K. Hiramoto et al.   Cancer Prevention Research

Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice

(2014) Yosuke Hirotsu et al.   GENES TO CELLS

Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice

(2014) Dewei Ye et al.   HEPATOLOGY

The Effects of LY2405319, an FGF21 Analog, in Obese Human Subjects with Type 2 Diabetes

(2013) Gregory Gaich et al.   Cell Metabolism

Nrf2 Protects Pancreatic  -Cells From Oxidative and Nitrosative Stress in Diabetic Model Mice

(2013) Y. Yagishita et al.   DIABETES

The Keap1-Nrf2 System Prevents Onset of Diabetes Mellitus

(2013) A. Uruno et al.   MOLECULAR AND CELLULAR BIOLOGY

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Fibroblast Growth Factor-21 Regulates PPARγ Activity and the Antidiabetic Actions of Thiazolidinediones

(2012) Paul A. Dutchak et al.   CELL

βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism

(2012) Xunshan Ding et al.   Cell Metabolism

Adipose Deficiency of Nrf2 in ob/ob Mice Results in Severe Metabolic Syndrome

(2012) P. Xue et al.   DIABETES

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system

(2012) Kai Takaya et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 deficiency in myeloid cells is not sufficient to protect mice from high-fat diet-induced adipose tissue inflammation and insulin resistance

(2012) Akshaya K. Meher et al.   FREE RADICAL BIOLOGY AND MEDICINE

FGF21 regulates PGC-1  and browning of white adipose tissues in adaptive thermogenesis

(2012) f. M. Fisher et al.   GENES & DEVELOPMENT

Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks

(2012) Yosuke Hirotsu et al.   NUCLEIC ACIDS RESEARCH

Nrf2 Represses FGF21 During Long-Term High-Fat Diet-Induced Obesity in Mice

(2011) D. V. Chartoumpekis et al.   DIABETES

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity

(2011) Fredirick L. Mashili et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Fibroblast Growth Factor 21 Induces Glucose Transporter-1 Expression through Activation of the Serum Response Factor/Ets-Like Protein-1 in Adipocytes

(2011) Xuan Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

All-trans retinoic acid and a novel synthetic retinoid tamibarotene (Am80) differentially regulate CD38 expression in human leukemia HL-60 cells: possible involvement of protein kinase C-δ

(2011) Akira Uruno et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Embryonic Lethality and Fetal Liver Apoptosis in Mice Lacking All Three Small Maf Proteins

(2011) H. Yamazaki et al.   MOLECULAR AND CELLULAR BIOLOGY

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

(2011) Akira Uruno et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Increased Fibroblast Growth Factor 21 in Obesity and Nonalcoholic Fatty Liver Disease

(2010) Jody Dushay et al.   GASTROENTEROLOGY

Deficiency in the Nuclear Factor E2-related Factor-2 Transcription Factor Results in Impaired Adipogenesis and Protects against Diet-induced Obesity

(2010) Jingbo Pi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Triterpenoid 2-Cyano-3,12-dioxooleana-1,9-dien-28-oic-acid Methyl Ester Has Potent Anti-diabetic Effects in Diet-induced Diabetic Mice andLeprdb/dbMice

(2010) Pradip K. Saha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome proliferator-activated receptor-  suppresses CYP11B2 expression and aldosterone production

(2010) A. Uruno et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Nuclear Factor Erythroid 2-Related Factor 2 Deletion Impairs Glucose Tolerance and Exacerbates Hyperglycemia in Type 1 Diabetic Mice

(2010) L. M. Aleksunes et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Genetic Analysis of Cytoprotective Functions Supported by Graded Expression of Keap1

(2010) K. Taguchi et al.   MOLECULAR AND CELLULAR BIOLOGY

Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse

(2010) Klementina Fon Tacer et al.   MOLECULAR ENDOCRINOLOGY

Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-Imidazolide

(2009) Soona Shin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes

(2009) Katsumi Iizuka et al.   FEBS LETTERS

Pancreatic lipase inhibitory activity of taraxacum officinale in vitro and in vivo

(2009) Jian Zhang et al.   Nutrition Research and Practice

Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans

(2008) X. Zhang et al.   DIABETES

Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice

(2008) J. Xu et al.   DIABETES

Fibroblast Growth Factor 21 Corrects Obesity in Mice

(2008) Tamer Coskun et al.   ENDOCRINOLOGY

Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity

(2008) T. Yamamoto et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipose Fibroblast Growth Factor 21 Is Up-Regulated by Peroxisome Proliferator-Activated Receptor   and Altered Metabolic States

(2008) E. S. Muise et al.   MOLECULAR PHARMACOLOGY