Novel oncogene and tumor suppressor mutations inKITandPDGFRAwild type gastrointestinal stromal tumors revealed by next generation sequencing

BRAF Mutant Gastrointestinal Stromal Tumor: First report of regression with BRAF inhibitor dabrafenib (GSK2118436) and whole exomic sequencing for analysis of acquired resistance

(2015) Gerald S. Falchook et al.   Oncotarget

Loss of ARID1A expression sensitizes cancer cells to PI3K- and AKT-inhibition

(2015) Eleftherios P. Samartzis et al.   Oncotarget

Recurrent SMARCA4 mutations in small cell carcinoma of the ovary

(2014) Petar Jelinic et al.   NATURE GENETICS

Dedifferentiation in Gastrointestinal Stromal Tumor to an Anaplastic KIT-negative Phenotype

(2013) Cristina R. Antonescu et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Novel Clinically Relevant Genes in Gastrointestinal Stromal Tumors Identified by Exome Sequencing

(2013) S. F. Schoppmann et al.   CLINICAL CANCER RESEARCH

No KRAS mutations found in gastrointestinal stromal tumors (GISTs): molecular genetic study of 514 cases

(2013) Jerzy Lasota et al.   MODERN PATHOLOGY

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

(2013) Gunther Zimmermann et al.   NATURE

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

(2013) Kristian Cibulskis et al.   NATURE BIOTECHNOLOGY

Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 kinase in KRAS -Mutant Lung Cancer

(2013) Miriam Molina-Arcas et al.   Cancer Discovery

KRAS and BRAF Mutations Predict Primary Resistance to Imatinib in Gastrointestinal Stromal Tumors

(2012) C. Miranda et al.   CLINICAL CANCER RESEARCH

Molecular Epidemiology of EGFR and KRAS Mutations in 3,026 Lung Adenocarcinomas: Higher Susceptibility of Women to Smoking-Related KRAS-Mutant Cancers

(2012) S. Dogan et al.   CLINICAL CANCER RESEARCH

Succinate Dehydrogenase Subunit B (SDHB) Is Expressed in Neurofibromatosis 1-Associated Gastrointestinal Stromal Tumors (Gists): Implications for the SDHB Expression Based Classification of Gists

(2012) Jeanny H. Wang et al.   Journal of Cancer

Detection of KRAS and BRAF Mutations in Colorectal Carcinoma

(2011) Maria Arcila et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Coexistence of PIK3CA and Other Oncogene Mutations in Lung Adenocarcinoma-Rationale for Comprehensive Mutation Profiling

(2011) J. E. Chaft et al.   MOLECULAR CANCER THERAPEUTICS

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Cell Cycle/Apoptosis Molecule Expression Correlates with Imatinib Response in Patients with Advanced Gastrointestinal Stromal Tumors

(2009) S. Romeo et al.   CLINICAL CANCER RESEARCH

Insulin-like growth factor (IGF) 1 and 2 help to predict disease outcome in GIST patients

(2008) C. Braconi et al.   ANNALS OF ONCOLOGY

Cigarette smoking and colorectal cancer incidence and mortality: Systematic review and meta-analysis

(2008) Peter S. Liang et al.   INTERNATIONAL JOURNAL OF CANCER