Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses

(2011) Corinne M. Spencer et al.   Autism Research

Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome

(2011) Alexia M. Thomas et al.   BEHAVIOURAL BRAIN RESEARCH

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

STEP regulation of seizure thresholds in the hippocampus

(2011) Stephen W. Briggs et al.   EPILEPSIA

Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory

(2011) Deepa V. Venkitaramani et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Impaired inhibitory control of cortical synchronization in fragile X syndrome

(2011) Scott M. Paluszkiewicz et al.   JOURNAL OF NEUROPHYSIOLOGY

Altered Neocortical Rhythmic Activity States in Fmr1 KO Mice Are Due to Enhanced mGluR5 Signaling and Involve Changes in Excitatory Circuitry

(2011) S. A. Hays et al.   JOURNAL OF NEUROSCIENCE

ERK2 Contributes to the Control of Social Behaviors in Mice

(2011) Y. Satoh et al.   JOURNAL OF NEUROSCIENCE

Genetic-Background Modulation of Core and Variable Autistic-Like Symptoms in Fmr1 Knock-Out Mice

(2011) Susanna Pietropaolo et al.   PLoS One

The behavioral phenotype of FMR1 mutations

(2010) Lia Boyle et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

Lithium ameliorates phenotypic deficits in a mouse model of fragile X syndrome

(2010) Zhong-Hua Liu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Excess Phosphoinositide 3-Kinase Subunit Synthesis and Activity as a Novel Therapeutic Target in Fragile X Syndrome

(2010) C. Gross et al.   JOURNAL OF NEUROSCIENCE

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

(2010) E. K. Osterweil et al.   JOURNAL OF NEUROSCIENCE

Defective GABAergic Neurotransmission and Pharmacological Rescue of Neuronal Hyperexcitability in the Amygdala in a Mouse Model of Fragile X Syndrome

(2010) J. L. Olmos-Serrano et al.   JOURNAL OF NEUROSCIENCE

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

GSK3 Influences Social Preference and Anxiety-Related Behaviors during Social Interaction in a Mouse Model of Fragile X Syndrome and Autism

(2010) Marjelo A. Mines et al.   PLoS One

Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer's disease mouse model

(2010) Y. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lithium ameliorates altered glycogen synthase kinase-3 and behavior in a mouse model of Fragile X syndrome

(2009) Christopher J. Yuskaitis et al.   BIOCHEMICAL PHARMACOLOGY

Dissociation of social and nonsocial anxiety in a mouse model of fragile X syndrome

(2009) Zhong-Hua Liu et al.   NEUROSCIENCE LETTERS

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

(2009) Alexia Thomas et al.   PSYCHOPHARMACOLOGY

Evidence for social anxiety and impaired social cognition in a mouse model of fragile X syndrome.

(2008) Caitlyn H. McNaughton et al.   BEHAVIORAL NEUROSCIENCE

Social approach in genetically engineered mouse lines relevant to autism

(2008) S. S. Moy et al.   GENES BRAIN AND BEHAVIOR

Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome

(2008) Jay R. Gibson et al.   JOURNAL OF NEUROPHYSIOLOGY

The Tyrosine Phosphatase STEP Mediates AMPA Receptor Endocytosis after Metabotropic Glutamate Receptor Stimulation

(2008) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

(2008) Femke M.S. de Vrij et al.   NEUROBIOLOGY OF DISEASE

Elongation Factor 2 and Fragile X Mental Retardation Protein Control the Dynamic Translation of Arc/Arg3.1 Essential for mGluR-LTD

(2008) Sungjin Park et al.   NEURON

Phospho-regulation of synaptic and extrasynaptic N-methyl-d-aspartate receptors in adult hippocampal slices

(2008) S.M. Goebel-Goody et al.   NEUROSCIENCE

Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome

(2008) S. H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unaltered hormonal response to stress in a mouse model of fragile X syndrome

(2008) Mei Qin et al.   PSYCHONEUROENDOCRINOLOGY

Knockout of STriatal enriched protein tyrosine phosphatase in mice results in increased ERK1/2 phosphorylation

(2008) Deepa V. Venkitaramani et al.   SYNAPSE