Inactivation of Pde8b enhances memory, motor performance, and protects against age-induced motor coordination decay

Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment

(2011) Isaac Levy et al.   CURRENT OPINION IN PHARMACOLOGY

Phosphodiesterase-4D Knock-Out and RNA Interference-Mediated Knock-Down Enhance Memory and Increase Hippocampal Neurogenesis via Increased cAMP Signaling

(2011) Y.-F. Li et al.   JOURNAL OF NEUROSCIENCE

Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety

(2011) Larry S Zweifel et al.   NATURE NEUROSCIENCE

Molecular substrates of action control in cortico-striatal circuits

(2011) Michael W. Shiflett et al.   PROGRESS IN NEUROBIOLOGY

Autosomal-Dominant Striatal Degeneration Is Caused by a Mutation in the Phosphodiesterase 8B Gene

(2010) Silke Appenzeller et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The High-Affinity cAMP-Specific Phosphodiesterase 8B Controls Steroidogenesis in the Mouse Adrenal Gland

(2010) L.-C. L. Tsai et al.   MOLECULAR PHARMACOLOGY

Impaired appetitively as well as aversively motivated behaviors and learning in PDE10A-deficient mice suggest a role for striatal signaling in evaluative salience attribution

(2010) Elisabeth Piccart et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

(2010) Viktor Lakics et al.   NEUROPHARMACOLOGY

CRF1-R Activation of the Dynorphin/Kappa Opioid System in the Mouse Basolateral Amygdala Mediates Anxiety-Like Behavior

(2010) Michael R. Bruchas et al.   PLoS One

Inhibition of the Striatal Specific Phosphodiesterase PDE10A Ameliorates Striatal and Cortical Pathology in R6/2 Mouse Model of Huntington's Disease

(2010) Carmela Giampà et al.   PLoS One

Ventral striatal plasticity and spatial memory

(2010) Valentina Ferretti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antidepressant- and Anxiolytic-like Effects of the Phosphodiesterase-4 Inhibitor Rolipram on Behavior Depend on Cyclic AMP Response Element Binding Protein-Mediated Neurogenesis in the Hippocampus

(2009) Yun-Feng Li et al.   NEUROPSYCHOPHARMACOLOGY

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

(2008) Lisette Arnaud-Lopez et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex

(2008) Anelia Horvath et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D−/−) mice

(2008) Kris Rutten et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Chronic G s Signaling in the Striatum Increases Anxiety-Related Behaviors Independent of Developmental Effects

(2008) C. Favilla et al.   JOURNAL OF NEUROSCIENCE

Distinct Roles of PDE4 and PDE10A in the Regulation of cAMP/PKA Signaling in the Striatum

(2008) A. Nishi et al.   JOURNAL OF NEUROSCIENCE

Diminished Phosphodiesterase-8B Potentiates Biphasic Insulin Response to Glucose

(2007) Avital Dov et al.   ENDOCRINOLOGY

The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory

(2003) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY