The immunoglobulin heavy chain locus: genetic variation, missing data and implications for human disease

Population-Genetic Properties of Differentiated Human Copy-Number Polymorphisms

(2011) Catarina D. Campbell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Segmental duplication as one of the driving forces underlying the diversity of the human immunoglobulin heavy chain variable gene region

(2011) Sreemanta Pramanik et al.   BMC GENOMICS

Wide Prevalence of Heterosubtypic Broadly Neutralizing Human Anti-Influenza A Antibodies

(2011) J. Sui et al.   CLINICAL INFECTIOUS DISEASES

Genomic screening by 454 pyrosequencing identifies a new human IGHV gene and sixteen other new IGHV allelic variants

(2011) Yan Wang et al.   IMMUNOGENETICS

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Inference of Phased Haplotypes for the Immunoglobulin H Chain V Region Gene Loci by Analysis of VDJ Gene Rearrangements

(2011) M. J. Kidd et al.   JOURNAL OF IMMUNOLOGY

Rare antibodies from combinatorial libraries suggests an S.O.S. component of the human immunological repertoire

(2011) Richard A. Lerner   Molecular BioSystems

Mapping copy number variation by population-scale genome sequencing

(2011) Ryan E. Mills et al.   NATURE

Identification of Novel Susceptibility Loci for Kawasaki Disease in a Han Chinese Population by a Genome-Wide Association Study

(2011) Fuu-Jen Tsai et al.   PLoS One

Comparison of Antibody Repertoires Produced by HIV-1 Infection, Other Chronic and Acute Infections, and Systemic Autoimmune Disease

(2011) Felix Breden et al.   PLoS One

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

(2011) J. Glanville et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ethnic Differences in VH Gene Polymorphism

(2010) E. H. SASSO et al.   Annals of the New York Academy of Sciences

Polymorphism and Utilization of Human VH Genesa

(2010) ERIC C. B. MILNER et al.   Annals of the New York Academy of Sciences

Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements

(2010) S. D. Boyd et al.   JOURNAL OF IMMUNOLOGY

IGHV4-39 deletion polymorphism does not associate with risk or outcome of multiple sclerosis

(2010) Corey T. Watson et al.   JOURNAL OF NEUROIMMUNOLOGY

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Characterization of missing human genome sequences and copy-number polymorphic insertions

(2010) Jeffrey M Kidd et al.   NATURE METHODS

Limitations of next-generation genome sequence assembly

(2010) Can Alkan et al.   NATURE METHODS

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Population-genetic nature of copy number variations in the human genome

(2009) Mamoru Kato et al.   HUMAN MOLECULAR GENETICS

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

(2009) Johannes F. Scheid et al.   NATURE

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Origins and functional impact of copy number variation in the human genome

(2009) Donald F. Conrad et al.   NATURE

Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

(2009) Jianhua Sui et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gross Deletions Involving IGHM, BTK, or Artemis: A Model for Genomic Lesions Mediated by Transposable Elements

(2008) Menno C. van Zelm et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Recent Advances in the Genetics of Autoimmune Disease

(2008) Peter K. Gregersen et al.   Annual Review of Immunology

Preferential use of the VH5-51 gene segment by the human immune response to code for antibodies against the V3 domain of HIV-1

(2008) Miroslaw K. Gorny et al.   MOLECULAR IMMUNOLOGY

Mapping and sequencing of structural variation from eight human genomes

(2008) Jeffrey M. Kidd et al.   NATURE

The HuRef Browser: a web resource for individual human genomics

(2008) Nelson Axelrod et al.   NUCLEIC ACIDS RESEARCH

Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells

(2008) Mark Throsby et al.   PLoS One

Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

(2008) A. K. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA