Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus

Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

(2012) Jingyuan Fu et al.   PLoS Genetics

A cytokine gene screen uncovers SOCS1 as genetic risk factor for multiple sclerosis

(2011) K Vandenbroeck et al.   GENES AND IMMUNITY

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA–CLEC16A–SOCS1 gene complex

(2011) Rebecca L. Zuvich et al.   HUMAN MOLECULAR GENETICS

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene

(2011) Lucy J. Davison et al.   HUMAN MOLECULAR GENETICS

SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-γ and IL-17A production

(2011) Reiko Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

(2011) S. Bhattacharyya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

More CLEC16A gene variants associated with multiple sclerosis

(2010) S. Nischwitz et al.   ACTA NEUROLOGICA SCANDINAVICA

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus

(2010) I-L Mero et al.   GENES AND IMMUNITY

Genetic variation in the IL7RA/IL7 pathway increases multiple sclerosis susceptibility

(2010) Rebecca L. Zuvich et al.   HUMAN GENETICS

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis

(2010) Paola G. Bronson et al.   HUMAN MOLECULAR GENETICS

Association of IFIH1 and other autoimmunity risk alleles with selective IgA deficiency

(2010) Ricardo C Ferreira et al.   NATURE GENETICS

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

Candidate Causal Regulatory Effects by Integration of Expression QTLs with Complex Trait Genetic Associations

(2010) Alexandra C. Nica et al.   PLoS Genetics

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-β

(2009) Luca Durelli et al.   ANNALS OF NEUROLOGY

A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis

(2009) B. Skinningsrud et al.   ANNALS OF THE RHEUMATIC DISEASES

Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15− Crohn's disease patients

(2009) Ana Márquez et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

SOCS1 negatively regulates the production of Foxp3+ CD4+ T cells in the thymus

(2009) Yifan Zhan et al.   IMMUNOLOGY AND CELL BIOLOGY

Replication of CD58 and CLEC16A as genome-wide significant risk genes for multiple sclerosis

(2009) Ilse A Hoppenbrouwers et al.   JOURNAL OF HUMAN GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians

(2008) J P Rubio et al.   GENES AND IMMUNITY

The expanding genetic overlap between multiple sclerosis and type I diabetes

(2008)   GENES AND IMMUNITY

Polymorphisms inCLEC16AandCIITAat 16p13 Are Associated with Primary Adrenal Insufficiency

(2008) Beate Skinningsrud et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM