期刊
GENES & DEVELOPMENT
卷 23, 期 14, 页码 1613-1618出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.1826409
关键词
Checkpoint; cell division; spindle position; cell polarity
The spindle position checkpoint (SPOC) is a regulatory mechanism that ensures accurate segregation of chromosomes in polarized cells during mitosis. In this issue of Genes & Development, Chan and Amon (pp. 1639-1649) identify a phosphoprotein phosphatase (Rts1-PP2A) as a new member of the checkpoint in budding yeast and define its role in interpreting spatial information during mitosis.
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