期刊
GENES & DEVELOPMENT
卷 22, 期 17, 页码 2302-2307出版社
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1101/gad.1719208
关键词
centromere; aneuploidy; mitosis; kinetochore; microtubule; spindle; chromosome
资金
- Association for International Cancer Resarch (AICR)
- Telethon Foundation
- EU [FP6]
- Italian Association for Cancer Research (AIRC)
- Fondo di Investimento per la Ricerca di Base (FIRB)
- Italian Ministry of Health
- Nando Peretti Foundation
The attachment of chromosomes to spindle microtubules during mitosis is a delicate and intricate process on which eukaryotic cells critically depend to maintain their ploidy. In this issue of Genes & Development, Gassmann and colleagues ( pp. 2385-2399) present an analysis of the recently discovered Spindly/SPDL-1 protein that casts new lights onto the attachment process and the way it relates to the control of cell cycle progression.
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