Article
Neurosciences
Tory Eisenlohr-Moul, Danielle A. Swales, David R. Rubinow, Lauren Schiff, Crystal E. Schiller
Summary: The hormonal changes during pregnancy and childbirth can affect a person's emotional state, especially for those with a history of postpartum depression. This study aimed to understand how hormone-sensitive individuals can be differentiated from hormone-insensitive controls and which symptoms show the most rapid and consistent response. The results showed that hormone-sensitive participants could be distinguished from controls early on in the study, with symptoms such as anger/irritability, mood swings, and fatigue showing the most significant changes within the first week of hormone manipulation. This study highlights the importance of reproductive hormones in perinatal affective disorders and suggests that anger and irritability may be early indicators of hormone sensitivity.
NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Endocrinology & Metabolism
Alexandra L. Cara, Emily L. Henson, Bethany G. Beekly, Carol F. Elias
Summary: This study revealed sex-specific expression of Ar in the mouse brain, showing that Ar is expressed in various brain areas during prepubertal development and may play an important role in female neuronal development and physiology.
JOURNAL OF NEUROENDOCRINOLOGY
(2021)
Article
Fisheries
Nhan Thanh Pham, Takafumi Amagai, Yuji Mushirobira, Ryosuke Murata, Kiyoshi Soyano
Summary: The blacktip grouper reaches maturity and spawns at around 3 years old, with some females maturing at 2 years. Plasma 17 beta-estradiol levels increase rapidly during puberty at 3 years old, while plasma 11-keto-testosterone levels increase significantly during sex change.
Article
Biotechnology & Applied Microbiology
Mingtao Liu, Qihui Zhu, Huan Li, Ruiyi Chen, Weihua Hu, Simiao Liu, Dongdong Xu
Summary: We investigated the early gonadal development in rock bream through histological observations. Females showed earlier differentiation compared to males. Treatment with letrozole (LTZ) and 17 alpha-methyltestosterone (MT) resulted in complete masculinization of genotype-females, while 17beta-estradiol (E-2) only partially feminized genotype-males. These findings contribute to the understanding of sex determination and differentiation in fishes with the X1X2Y sex chromosome system and provide a sex reversal protocol for rock bream.
MARINE BIOTECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
H. E. Flay, C. B. Reed, B. Kuhn-Sherlock, C. V. C. Phyn, C. R. Burke, S. Meier, I. J. Clarke
Summary: Previous research has found that Holstein-Friesian dairy heifers with positive genetic merit for fertility traits reach puberty earlier than those with negative genetic merit. This study investigated the functionality of the hypothalamus-pituitary-gonadal (HPG) axis in peripubertal heifers with divergent genetic merit, finding that the earlier onset of puberty in positive heifers is associated with earlier activation of the HPG axis.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Environmental Sciences
Chang-Beom Park, Go-Eun Kim, Jiwon On, Heesoo Pyo, June-Woo Park, Sung-Hee Cho
Summary: This study found that bisphenol S (BPS) exposure has adverse effects on reproductive endocrine activity in adult zebrafish, with mechanisms involving sex differences and tissue-specific responses. Female fish showed decreased hepatic vitellogenin (VTG) mRNA biosynthesis, while male fish showed increased VTG mRNA biosynthesis. Exposure led to increased levels of gonadal steroids in female zebrafish and decreased levels of endogenous androgens in male fish, with elevated activities of 17 beta-estradiol and aromatase in all BPS exposure groups in male zebrafish.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Clinical Neurology
Liang-Jen Wang, Ying-Hua Huang, Wen-Jiun Chou, Sheng-Yu Lee, Ching-Shu Tsai, Min-Jing Lee, Miao-Chun Chou
Summary: This study found changes in gonadal hormones in ADHD patients undergoing long-term MPH treatment, but usual doses of MPH did not significantly alter their gonadal function trends.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2021)
Review
Biochemistry & Molecular Biology
Sara Trova, Serena Bovetti, Sara Bonzano, Silvia De Marchis, Paolo Peretto
Summary: Steroid hormones play important roles in vertebrates, especially in mammalian sexual development and brain neural circuits. Studies in recent decades have shown that sex steroids influence the organization of the brain structure during puberty, a critical period characterized by high sensitivity to external stimuli and significant remodeling of the organism's structure and function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agriculture, Dairy & Animal Science
Malgorzata Gumulka, Nataly Avital-Cohen, Israel Rozenboim
Summary: This study investigated the annual hormone patterns in ganders and female geese, finding differences between the sexes during the breeding-laying period, with ganders potentially terminating the period earlier than female geese, which could be crucial for extending the seasonal hatching egg production.
Article
Biochemistry & Molecular Biology
Pawel Likszo, Katarzyna Gromadzka-Hliwa, Jan Klos, Monika M. Kaczmarek, Adam J. Ziecik
Summary: This study focuses on the routine procedure of estrous cycle synchronization in pigs and the use of gonadotropins to stimulate ovarian activity. The research reveals the importance of sexual maturity in maintaining the estrogenic environment and the moderate role of eCG and FSH in activating steroidogenic enzymes in preovulatory follicles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Psychology, Developmental
David J. Piekarski, Natalie L. Colich, Tiffany C. Ho
Summary: Adolescence is a period of rapid brain development, and the changes in white matter are partly attributed to hormonal fluctuations. This systematic review examines the associations between hormonal changes and white matter properties across species, with a focus on sex differences. The review finds that increases in gonadal hormones during puberty are associated with structural changes in white matter tracts, particularly in the corpus callosum, which align with findings in non-human animals. The paper concludes with recommendations for future research in order to further understand the neuroscience of puberty.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2023)
Article
Orthopedics
Xun Ma, Zhan Zhang, Xinyuan Kang, Chunbo Deng, Yingwei Sun, Yanjun Li, Desheng Huang, Xueyong Liu
Summary: In this study, male Dunkin-Hartley guinea pigs were used to investigate the expression of Matrix Gla (gamma-carboxyglutamate) protein (MGP) throughout aging and disease pathogenesis. The results showed that MGP levels increased significantly with advancing age, and this may be linked to increased OA severity. Further studies are needed to confirm the association between MGP levels and OA severity.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Review
Endocrinology & Metabolism
Giuseppa Patti, Marco Scaglione, Nadia Gabriella Maiorano, Giulia Rosti, Maria Teresa Divizia, Tiziana Camia, Elena Lucia De Rose, Alice Zucconi, Emilio Casalini, Flavia Napoli, Natascia Di Iorgi, Mohamad Maghnie
Summary: In this narrative review, the authors summarized the available data on puberty and gonadal function in Noonan syndrome (NS) subjects and discussed the role of the RAS/mitogen-activated protein kinase (MAPK) signalling pathway in fertility. NS patients tend to have a delay in puberty onset compared to healthy children, and males with NS are at risk of gonadal dysfunction due to factors including cryptorchidism, the MAP/MAPK pathway, and genetics. Long-term studies on a large cohort of NS patients are needed to better understand the impact of delayed puberty on adult height, metabolic profile, and well-being. Genetic counseling and fertility-related issues are crucial.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Endocrinology & Metabolism
Sara Prosperi, Francesco Chiarelli
Summary: During the COVID-19 pandemic, the implementation of strict measures like lockdowns and school closures caused significant disruptions in the lives of children and adolescents, leading to a sedentary lifestyle, increased use of electronic devices, and higher levels of stress-related symptoms. Studies have reported an increase in early and precocious puberty cases during this period, suggesting a potential role of environmental and lifestyle factors in triggering earlier pubertal onset. It is important to further investigate the exact impact of COVID-19 on pubertal development through global studies and long-term research.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Psychology, Developmental
Frank M. Biro, Suzanne S. Summer, Bin Huang, Chen Chen, Janie Benoit, Susan M. Pinney
Summary: This study examines the relationship between dietary fiber and protein intake and estrogen and sex hormone-binding globulin (SHBG) concentrations at the onset of puberty. The findings suggest that higher protein intake, especially from animal sources, is associated with increased estrogen concentrations and decreased SHBG levels, leading to higher levels of bioavailable estrogen. These results indicate that modest reduction in animal protein intake may be beneficial in reducing the risk of breast cancer.
JOURNAL OF ADOLESCENT HEALTH
(2022)
Article
Endocrinology & Metabolism
Xiaomeng Li, Charles Brighton Ndandala, Qi Zhou, Chunyan Huang, Guangli Li, Huapu Chen
Summary: This study investigated the role of estrogen receptors (ERs) in vitellogenesis (Vtgs) regulation in pompano fish. The findings suggest that E2 may regulate the expression of different subtypes of vtg through ERs, displaying a compensatory expression effect on the regulation of ers and vtgs. This provides a theoretical basis for further research on reproductive endocrinology in pompano fish.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Norio Kansaku, Takeshi Ohkubo
Summary: Endocrine changes during bird reproduction, particularly the relationship between prolactin and incubation behavior, were investigated. The study monitored the physiological status and incubation behavior of Silkie hens over 1-2 years. The results showed that most mature hens exhibited incubation behavior multiple times, and there was a noticeable increase in nest occupancy 7-10 days before incubation onset. Protein analysis revealed that secreted prolactin during the reproductive cycle contains various isoforms, suggesting post-translational modifications like glycosylation and phosphorylation.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Minghui Li, Lina Sun, Linyan Zhou, Deshou Wang
Summary: This article summarizes the importance of the Nile tilapia as an excellent animal model for studying reproductive endocrinology in fish, with a focus on the crucial role of estrogen in female development.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)
Article
Endocrinology & Metabolism
Breanna N. Harris, Carolyn M. Bauer, James A. Carr, Caitlin R. Gabor, Jennifer L. Grindstaff, Caleigh Guoynes, Jennifer J. Heppner, Cris C. Ledon-Rettig, Patricia C. Lopes, Sharon E. Lynn, Carla B. Madelaire, Lorin A. Neuman-Lee, Maria G. Palacios, Paul Soto, Jennifer Terry
Summary: The COVID-19 pandemic had a significant impact on academics, particularly on those with minoritized identities or who were early career, caregivers, or had intersecting identities. The pandemic altered the impact factors of academia, including scholarly products, and affected the way individuals could respond. It is predicted that the pandemic will have long-term impacts on the population dynamics, composition, and landscape of the academic ecosystem. The number of journal submissions decreased, especially among women authors, and the pandemic heavily impacted women authors from Asia and the Middle East.
GENERAL AND COMPARATIVE ENDOCRINOLOGY
(2024)