In vivo delivery of DN:REST improves transcriptional changes of REST-regulated genes in HD mice

The human visual cortex responds to gene therapy–mediated recovery of retinal function

(2011) Manzar Ashtari et al.   JOURNAL OF CLINICAL INVESTIGATION

Ethanol-induced neurodegeneration in NRSF/REST neuronal conditional knockout mice

(2011) L. Cai et al.   NEUROSCIENCE

Emerging roles for cholesterol in Huntington's disease

(2011) Marta Valenza et al.   TRENDS IN NEUROSCIENCES

Expression and functions of the repressor element 1 (RE-1)-silencing transcription factor (REST) in breast cancer

(2010) Hui Lv et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Rescue of gene expression by modified REST decoy oligonucleotides in a cellular model of Huntington’s disease

(2010) Chiara Soldati et al.   JOURNAL OF NEUROCHEMISTRY

Molecular Mechanisms and Potential Therapeutical Targets in Huntington's Disease

(2010) Chiara Zuccato et al.   PHYSIOLOGICAL REVIEWS

Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease

(2009) Angela Bithell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Analysis of the Repressor Element-1 Silencing Transcription Factor/Neuron-Restrictive Silencer Factor Occupancy of Non-Neuronal Genes in Peripheral Lymphocytes from Patients with Huntington's Disease

(2009) Manuela Marullo et al.   BRAIN PATHOLOGY

DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down syndrome

(2009) Aude-Marie Lepagnol-Bestel et al.   HUMAN MOLECULAR GENETICS

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease

(2009) A. N. Packer et al.   JOURNAL OF NEUROSCIENCE

Nonallele-specific Silencing of Mutant and Wild-type Huntingtin Demonstrates Therapeutic Efficacy in Huntington's Disease Mice

(2009) Ryan L Boudreau et al.   MOLECULAR THERAPY

Gene Therapy for Leber's Congenital Amaurosis is Safe and Effective Through 1.5 Years After Vector Administration

(2009) Francesca Simonelli et al.   MOLECULAR THERAPY

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Safety and tolerability of putaminal AADC gene therapy for Parkinson disease

(2009) C. W. Christine et al.   NEUROLOGY

Gene Dysregulation in Huntington’s Disease: REST, MicroRNAs and Beyond

(2009) Rory Johnson et al.   NEUROMOLECULAR MEDICINE

DYRK1A-Dosage Imbalance Perturbs NRSF/REST Levels, Deregulating Pluripotency and Embryonic Stem Cell Fate in Down Syndrome

(2008) Claudia Canzonetta et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington’s disease

(2008) Samantha Leone et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Huntingtin Regulates RE1-silencing Transcription Factor/Neuron-restrictive Silencer Factor (REST/NRSF) Nuclear Trafficking Indirectly through a Complex with REST/NRSF-interacting LIM Domain Protein (RILP) and Dynactin p150Glued

(2008) Masahito Shimojo   JOURNAL OF BIOLOGICAL CHEMISTRY

Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice

(2008) M. Gray et al.   JOURNAL OF NEUROSCIENCE

REST Regulates Distinct Transcriptional Networks in Embryonic and Neural Stem Cells

(2008) Rory Johnson et al.   PLOS BIOLOGY

A microRNA-based gene dysregulation pathway in Huntington's disease

(2007) Rory Johnson et al.   NEUROBIOLOGY OF DISEASE