Article
Food Science & Technology
Asako Narai-Kanayama, Shin-ichi Yokosaka, Yuji Seo, Kouji Mikami, Takayuki Yoshino, Hiroko Matsuda
Summary: This study found that raw spinach leaves contain 0.4-1.5 mg/100 g of phytol. The phytol content in smoothies made from spinach leaves can be increased through enzymatic reactions. These findings are useful for controlling the phytol content in smoothies.
JOURNAL OF FOOD SCIENCE
(2023)
Article
Plant Sciences
Yun Jiang, Zihang Shi, Wei Liu, Mingfang Qi, Tao Xu, Yuanhua Wu, Tianlai Li
Summary: This study discovered a subfamily F protein phosphatase, SlPP2C, which is associated with leaf senescence. The expression, protein accumulation, and promoter activity of SlPP2C increased gradually with the progression of leaf and flower senescence as well as fruit ripening in tomato. RNA interference of SlPP2C resulted in delayed senescence and ripening phenotypes in leaves, flowers, and fruits.
PHYSIOLOGIA PLANTARUM
(2023)
Article
Plant Sciences
Yan Li, Chang Liu, Qinghua Shi, Fengjuan Yang, Min Wei
Summary: The study investigated the effects of red (R) and blue (B) light on endogenous melatonin levels and fruit quality during tomato ripening. It was found that melatonin levels decreased as fruit ripened, but were noticeably enhanced with mixed red and blue (RB) light, leading to accelerated fruit softening and increased ethylene and lycopene biosynthesis. The findings suggest that RB light may regulate endogenous melatonin, promoting fruit ripening and quality improvement in tomatoes through cross-talk with other biomolecules and increased ethylene production and signaling.
ENVIRONMENTAL AND EXPERIMENTAL BOTANY
(2021)
Article
Biochemistry & Molecular Biology
Wei Huang, Nan Hu, Zhina Xiao, Yuping Qiu, Yan Yang, Jie Yang, Xin Mao, Yichuan Wang, Zhengguo Li, Hongwei Guo
Summary: Ethylene plays a critical role in tomato fruit growth and ripening by modulating auxin biosynthesis/signaling and activating fruit development-related genes.
Article
Plant Sciences
Yudong Liu, Yuan Shi, Deding Su, Wang Lu, Zhengguo Li
Summary: SlGRAS4 acts as a new regulator of fruit ripening by directly regulating ethylene biosynthesis genes, accelerating tomato fruit ripening and increasing carotenoid content.
HORTICULTURE RESEARCH
(2021)
Article
Plant Sciences
Fenfen Li, Mengjie Fu, Shengen Zhou, Qiaoli Xie, Guoping Chen, Xuqing Chen, Zongli Hu
Summary: In this study, the tomato HD-Zip transcription factor VAHOX1 was found to be involved in fruit ripening. Suppression of VAHOX1 accelerated fruit ripening, increased sensitivity to ethylene, and enhanced carotenoid content and ethylene production in tomato fruits. Conversely, overexpression of VAHOX1 had the opposite effect. VAHOX1 affected the expression of genes involved in ethylene biosynthesis, signal transduction, and cell wall modification. The findings expand our knowledge of the physiological functions of HD-Zip transcription factors in tomato and highlight the diversity of transcriptional regulation during fruit ripening.
HORTICULTURE RESEARCH
(2023)
Article
Plant Sciences
Kapil Sharma, Soni Gupta, Supriya Sarma, Meenakshi Rai, Yellamaraju Sreelakshmi, Rameshwar Sharma
Summary: This study reveals the role of ethylene in the development of tomato plants, not only in ripening but also in vegetative and reproductive processes. Mutants acs2-1 and acs2-2 exhibit contrasting ethylene emission levels and responses, impacting physiological and metabolic profiles of tomatoes.
Article
Plant Sciences
Ke Teng, Yuesen Yue, Hui Zhang, Hui Li, Lixin Xu, Chao Han, Xifeng Fan, Juying Wu
Summary: ZjPPH plays a crucial role in chlorophyll degradation and senescence, with its overexpression accelerating chlorophyll breakdown and promoting senescence by mainly suppressing PSII and PSI to inhibit photosynthetic efficiency.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Zhi-Kun Geng, Lin Ma, Yu-Lei Rong, Wan-Jie Li, Gai-Fang Yao, Hua Zhang, Kang-Di Hu
Summary: In this study, a tomato methionine synthase named SlMS1 was found to play a positive regulatory role in tomato fruit ripening. Further investigation showed that SlMS1 could up-regulate the expression of genes related to carotenoid synthesis, chlorophyll degradation, cell wall metabolism, and ethylene synthesis pathway, thereby promoting fruit ripening. These findings provide important insights into the molecular mechanism of tomato fruit ripening.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Plant Sciences
Yu-Qi Zhao, Kang-Di Hu, Gai-Fang Yao, Si-Yue Wang, Xiang-Jun Peng, Hua Zhang
Summary: In this study, the role of SlDCD2 gene in tomato fruit ripening was investigated. Silencing of SlDCD2 accelerated fruit ripening and led to premature leaf senescence. Furthermore, the mutation of SlDCD2 resulted in excessive H2O2 accumulation and increased ethylene release, indicating the involvement of H2S and SlDCD2 in modulating ROS homeostasis and ethylene biosynthesis.
HORTICULTURE RESEARCH
(2023)
Article
Plant Sciences
Jaclyn A. Adaskaveg, Christian J. Silva, Peng Huang, Barbara Blanco-Ulate
Summary: Mutations related to tomato fruit ripening were found to cause developmental defects before ripening, with some ripening changes still occurring; differences in plant hormone metabolism and signaling were also observed among different mutants.
FRONTIERS IN PLANT SCIENCE
(2021)
Review
Plant Sciences
Yucheng Ming, Libo Jiang, Dongchao Ji
Summary: This review discusses the recent advances in epigenetic regulation of tomato fruit ripening, including DNA methylation, N6-Methyladenosine mRNA modification, histone demethylation/deacetylation, and non-coding RNA. This research contributes to a better understanding of the regulatory mechanisms governing tomato fruit ripening and provides new insights for precise modulation of these mechanisms.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Changan Zhu, Shaofang Wu, Ting Sun, Zhiwen Zhou, Zhangjian Hu, Jingquan Yu
Summary: Rosmarinic acid (RA) treatment in postharvest significantly delayed ripening, reduced ethylene production, inhibited color change, promoted amino acid accumulation, and enhanced antioxidant activity in tomato fruits. These findings indicate a novel function of RA in fruit ripening, offering an attractive strategy to manage and improve the quality of tomato fruits.
Review
Plant Sciences
Zhiya Liu, Xuetong Wu, Huwei Liu, Meiling Zhang, Weibiao Liao
Summary: Fruit ripening is regulated by transcription factors, plant hormone ethylene, and DNA methylation. DNA methylation affects fruit ripening by transferring methyl groups. Tomato fruit ripening is dynamically regulated by DNA methylation and demethylation, but the specific molecular mechanism is still unclear.
PHYSIOLOGIA PLANTARUM
(2022)
Article
Plant Sciences
Jose F. Sanchez-Sevilla, Miguel A. Botella, Victoriano Valpuesta, Victoria Sanchez-Vera
Summary: Autophagy is a catabolic and recycling pathway essential for maintaining cellular homeostasis in plants. In cultivated strawberry fruits, autophagy occurs in two waves, characterized by differential expression of ATG genes and ATG8 lipidation. This process plays a significant role in fruit ripening, affecting growth and development.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Juliana Almeida, Laura Perez-Fons, Paul D. Fraser
Summary: High temperatures can negatively influence plant growth and development, including the quality traits of fruits. Research on tomato fruit exposed to heat stress revealed changes in nutritional attributes and disruptions in carotenogenesis and plastidial isoprenoid compounds. Metabolite profiling showed limited effects on primary metabolism but lipid remodelling, sucrose accumulation, and membrane lipid saturation changes were evident.
PLANT CELL AND ENVIRONMENT
(2021)
Review
Plant Sciences
Patricia Juliana Lopes-Oliveira, Halley Caixeta Oliveira, Zsuzsanna Kolbert, Luciano Freschi
Summary: This review examines the role of nitric oxide (NO) in controlling plant growth, development, metabolism, and stress responses through its interactions with light and hormonal signaling cascades. It also discusses the versatile functions of NO in regulating photosynthesis and stomatal movements, highlighting the importance of nitrate reductase (NR) regulation for adjusting NO production in plants exposed to natural light conditions.
JOURNAL OF EXPERIMENTAL BOTANY
(2021)
Article
Plant Sciences
Juliana L. Costa, Daniele Paschoal, Eder M. da Silva, Jamille S. Silva, Rafael M. do Carmo, Esther Carrera, Isabel Lopez-Diaz, Monica L. Rossi, Luciano Freschi, Piotr Mieczkowski, Lazaro E. P. Peres, Paulo J. P. L. Teixeira, Antonio Figueira
Summary: The study found that Moniliophthora perniciosa may induce abnormal stem development in the host by regulating host cytokinin metabolism, and iP produced by the pathogen may facilitate cytokinin synthesis in the host, exacerbating symptoms such as stem swelling.
Article
Plant Sciences
Daniele Rosado, Amanda Ackermann, Olya Spassibojko, Magdalena Rossi, Ullas Pedmale
Summary: This study investigates the mechanisms by which plants restrict root growth in response to low red:far-red light, a shade-avoidance response. The researchers identified a set of shade-induced genes that are regulated by WRKY transcription factors and ethylene hormone signaling. These genes play a crucial role in limiting primary and lateral root growth in shade conditions. The findings provide important insights into the molecular mechanisms of shade-avoidance response in plants.
Article
Genetics & Heredity
Paula M. Elbl, Diego T. de Souza, Daniele Rosado, Leandro F. de Oliveira, Bruno Navarro, Sergio R. Matioli, Eny I. S. Floh
Summary: This study investigated the evolutionary history of embryo patterning and auxin metabolism genes in plants using domain architecture phylostratigraphy and phylogenetic reconstruction. The results revealed the importance of auxin metabolism and other molecular mechanisms in the evolution and formation of plant embryos. These findings have potential implications for conservation programs and improving somatic embryogenesis.
Article
Biochemistry & Molecular Biology
Vanessa Fuentes Suguiyama, Jae Diana Paredes Rodriguez, Tatiane Cristina Nicomedio dos Santos, Bruno Silvestre Lira, Luis Alejandro de Haro, Joao Paulo Naldi Silva, Eduardo Leite Borba, Eduardo Purgatto, Emerson Alves da Silva, Nicolas Bellora, Fernando Carrari, Danilo da Cruz Centeno, Luisa Fernanda Bermudez, Magdalena Rossi, Nathalia de Setta
Summary: Drought is a major environmental stress that negatively affects plant growth and reproductive yield. The response to water deficit is determined by the duration and intensity of the stress, as well as the genetic makeup of the plant. The metabolic adjustments in response to water deficit involve complex gene expression regulation, including DNA-binding proteins and epigenetic modifications. In this study, Setaria italica plants exposed to different levels of water deficit were analyzed, and the results showed a progressive reduction in yield with increasing water deficit intensity. The signaling pathway modulation and metabolic adjustments were found to be associated with this response. Furthermore, certain loci related to drought perception, signaling, and regulation were consistently associated with drought responses. The analysis of the transcriptome and sRNAome also revealed potential gene regulation mechanisms involving transposable elements and sRNAs, as well as an intriguing correlation between transcript levels and sRNA accumulation. These findings provide insights into the processes that enable S. italica to overcome drought and survive under water restrictive conditions.
PLANT MOLECULAR BIOLOGY
(2022)
Article
Plant Sciences
Wilton R. Sala-Carvalho, Francisco P. Montessi-Amaral, Marisia P. Esposito, Richard Campestrini, Magdalena Rossi, Denilson F. Peralta, Claudia M. Furlan
Summary: The study investigated the effects of seasonality on the metabolome and redox status of the moss Ceratodon purpureus, revealing changes in metabolic compounds and antioxidant system during the dry period.
Article
Plant Sciences
Ricardo Bianchetti, Nicolas Bellora, Luis A. de Haro, Rafael Zuccarelli, Daniele Rosado, Luciano Freschi, Magdalena Rossi, Luisa Bermudez
Summary: Phytochrome-mediated light and temperature perception plays an important role in regulating fruit development, ripening, and nutritional quality. This study reveals that the regulation of fruit development by Phytochrome involves epigenetic mechanisms, specifically DNA demethylation. The findings show that Phytochrome has a greater impact on the methylome and transcriptome of tomato fruits in the breaker stage compared to the immature green stage. Additionally, PHYB1B2 has a more substantial effect on ripening-associated methylation reprogramming. The study also uncovers a gene expression network involving chromatin organization factors and transcriptional regulators that mediate the PHYB1B2 signal transduction. These findings provide insights into how epigenetic mechanisms respond to environmental cues and affect agronomical traits.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Bruno Silvestre Lira, Maria Jose Oliveira, Lumi Shiose, Mateus Henrique Vicente, Gabriel Ponciano Carvalho Souza, Eny Iochevet Segal Floh, Eduardo Purgatto, Fabio Tebaldi Silveira Nogueira, Luciano Freschi, Magdalena Rossi
Summary: SlBBX28 is a positive regulator of auxin metabolism and signaling, affecting plant growth and flower number in tomato. It promotes auxin production and signaling, ultimately leading to proper hypocotyl elongation, leaf expansion, and inflorescence development, which are crucial traits determining tomato yield.
PLANT MOLECULAR BIOLOGY
(2022)
Article
Plant Sciences
Juliene D. R. Moreira, Bruno L. Rosa, Bruno S. Lira, Joni E. Lima, Ludmila N. F. Correia, Wagner C. Otoni, Antonio Figueira, Luciano Freschi, Tetsu Sakamoto, Lazaro E. P. Peres, Magdalena Rossi, Agustin Zsogon
Summary: The distribution of heterobaric and homobaric leaves in tomatoes is controlled by a single-nucleotide polymorphism in a transcription factor gene. This mutation exists in wild tomatoes and has increased in frequency in domesticated tomatoes, affecting leaf growth and morphological characteristics.
Article
Neurosciences
Yohan S. S. Auguste, Austin Ferro, Jessica A. Kahng, Andre M. Xavier, Jessica R. Dixon, Uma Vrudhula, Anne-Sarah Nichitiu, Daniele Rosado, Tse-Luen Wee, Ullas Pedmale, Lucas Cheadle
Summary: Oligodendrocyte precursor cells contribute to the elimination of thalamocortical presynapses in response to sensory experience.
NATURE NEUROSCIENCE
(2022)
Correction
Neurosciences
Yohan S. S. Auguste, Austin Ferro, Jessica A. Kahng, Andre M. Xavier, Jessica R. Dixon, Uma Vrudhula, Anne-Sarah Nichitiu, Daniele Rosado, Tse-Luen Wee, Ullas Pedmale, Lucas Cheadle
NATURE NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Bruno Silvestre Lira, Giovanna Gramegna, Paula Amaral, Juliene dos Reis Moreira, Raquel Tsu Ay Wu, Mateus Henrique Vicente, Fabio Tebaldi Silveira Nogueira, Luciano Freschi, Magdalena Rossi
Summary: Chlorophyll catabolism is the primary source of phytyl diphosphate for tocopherol synthesis. The enzymes VTE5 and VTE6 are crucial for recycling chlorophyll-derived phytol and they are complexed, mitigating their cytotoxic nature. Tocopherol accumulation also occurs in chlorophyll-devoid organs, showing the importance of phytol recycling for tocopherol biosynthesis.
PLANT MOLECULAR BIOLOGY
(2023)
Article
Genetics & Heredity
Xiangge Meng, Chengping Li, Yu Hei, Xiang Zhou, Guoli Zhou
Summary: The study used IVT-SAPAS sequencing to analyze the dynamic changes of APA sites during adipogenesis in bovine subcutaneous preadipocytes and intramuscular preadipocytes. The results showed that APA plays an important role in adipocyte differentiation, and UTR-APA switching genes have different trends, with intramuscular preadipocytes tending to use shorter 3'UTR for differentiation. TRIB3, WWTR1, and INSIG1 play important roles in intramuscular preadipocyte differentiation.
Article
Genetics & Heredity
S. Alizadeh, S. Khamse, N. Tajeddin, H. R. Khorram Khorshid, A. Delbari, M. Ohadi
Summary: This study identifies a specific genotype at a CG-rich trinucleotide short tandem repeat (STR) locus that is associated with late-onset neurocognitive disorders such as Alzheimer's disease (AD).
Article
Genetics & Heredity
Shougang Liu, Zhe Zhuang, Fanghua Liu, Xiuqing Yuan, Zeqiao Zhang, Xiaoqian Liang, Xinhui Li, Yongfeng Chen
Summary: This study investigated the effect and mechanism of RPL9 and TIFA in scalp psoriasis, and identified RPL9 as a potential therapeutic target for scalp psoriasis.
Article
Genetics & Heredity
Shiting Wang, Jiaqi Chen, Zhichao Jin, Ying Xing, Ruiping Wang
Summary: This study suggests a causal association between hair color and skin cancers, with light hair colors (red, blonde, and light brown) being associated with an increased risk and dark brown hair being associated with a decreased risk.
Article
Genetics & Heredity
Joseph Hawadak, Loick Pradel Kojom Foko, Rodrigue Roman Dongang Nana, Karmveer Yadav, Veena Pande, Aparup Das, Vineeta Singh
Summary: This study investigates the genetic diversity and natural selection of the Pfama-1 gene in Plasmodium falciparum isolates from Cameroon. The study finds a considerable nucleotide and haplotype diversity, as well as specific mutations in Cameroonian isolates. Positive diversifying selection and the identification of selected codon sites suggest the potential implication of these genetic variations in host immune pressure and parasite-binding complex modulation. The findings provide valuable baseline data for malaria vaccine design.
Article
Genetics & Heredity
Emily Biernat, Mansi Verma, Chhabi K. Govind
Summary: RSC is an essential ATP-dependent chromatin remodeling complex in Saccharomyces cerevisiae. It regulates nucleosome-depleted regions (NDRs) by sliding flanking nucleosomes away from NDRs. Depletion of RSC leads to nucleosome encroachment in NDRs and transcription initiation defects. The study compared the effects of catalytic-dead Sth1 and rapid depletion of Sth1 on transcription. Rapid depletion of Sth1 reduces recruitment of TBP and Pol II, while the catalytic-dead mutant exhibits a severe reduction in TBP binding but accumulates Pol II in coding regions. The results suggest a role for RSC in transcription elongation and termination processes.
Article
Genetics & Heredity
Yunxiao Wei, Yuhan Song, Muhammad Aamir Khan, Chengzhen Liang, Zhigang Meng, Yuan Wang, Sandui Guo, Rui Zhang
Summary: This study analyzed the GhTPP protein family in upland cotton for the first time and identified the important role of GhTPPA_2 in regulating sugar metabolism, improving soluble sugar accumulation, and drought stress tolerance.
Article
Genetics & Heredity
Yannan Geng, Rui Shao, Tiantong Xu, Lilong Zhang
Summary: A novel risk model based on SCUBE3, TNNC1, SPON1, SEPT12 and ULBP1 genes was developed for predicting PMOP risk, with higher risk score indicating higher risk of suffering from PMOP. Significant differences in signaling pathway activities were observed between the high-risk score group and the low-risk score group.
Article
Genetics & Heredity
Randy P. Williams, Corina Lesseur, Haoxiang Cheng, Qian Li, Maya Deyssenroth, Christopher D. Molteno, Ernesta M. Meintjes, Sandra W. Jacobson, Joseph L. Jacobson, Helen Wainwright, Ke Hao, Jia Chen, R. Colin Carter
Summary: The study suggests that heavy alcohol exposure during pregnancy may impact the proportion of fetal placental villi macrophages and increase the expression of inflammatory genes. Further research is needed to explore these effects and evaluate the potential functional roles of placental inflammation in FASD.
Article
Genetics & Heredity
Lvjing Luo, Lishuang Sun, Shu Li, Huiting Liu, Zhengyu Chen, Shi Huang, Yinyin Mo, Genliang Li
Summary: This study analyzed the expression of Ptpn1 and miR-124-3p in testicular tissues of mice and investigated their regulatory relationship. The results showed that Ptpn1 expression was up-regulated in adult mouse testis compared to juvenile mouse testis, while miR-124-3p expression showed an opposite pattern. Further analysis suggested that the down-regulation of miR-124-3p may contribute to the high expression of Ptpn1 in adult mouse testis.
Article
Genetics & Heredity
Gairui Li, Dan Zhao, Xiaolin Peng, Yashuang Zhao
Summary: MiRNA-22 shows potential as a candidate for early diagnosis of colorectal cancer (CRC). The study found higher miR-22 expression levels in the CRC and CRA groups, suggesting its potential as a biomarker for CRC early screening.
Article
Genetics & Heredity
Zhongqiu Zhu, Qianting Yang, Xiaoying Tian, Da Man, Jian Wang, Junfang Zhang, Bingshe Han
Summary: This study constructed a ceRNA network mediated by lncRNAs in cold-acclimated zebrafish ZF4 cells and revealed that upregulation of MSTRG3207 promotes apoptosis by sponging dre-miR-736 during cold acclimation.
Article
Genetics & Heredity
Weitao Chen, Denggao Xiang, Shang Gao, Shuli Zhu, Zhi Wu, Yuefei Li, Jie Li
Summary: Dam construction has negatively impacted the genetic diversity and structure of fish populations. This case study on the endangered Hemibagrus guttatus found low genetic diversity, high levels of inbreeding, and decreasing population size in fragmented populations. Genetic structure and differentiation were also observed, indicating the influence of dams on these fish populations.
Article
Genetics & Heredity
Pooja Singh, Debleena Guin, Bijay Pattnaik, Ritushree Kukreti
Summary: Through systematic literature review and meta-analysis, it was found that idiopathic pulmonary fibrosis is significantly associated with 222 polymorphisms in 118 genes. Four polymorphisms - rs35705950/MUC5B, rs2736100/TERT, rs2076295/DSP, and rs111521887/TOLLIP, exhibited substantial epidemiological evidence supporting their association with IPF risk.
Article
Genetics & Heredity
Jianping Zhang, Zhijun Cai, Fanzhe Feng, Yufeng Peng, Yi Cui, Yongiqing Xu
Summary: This study found that exosomes secreted by young BMSCs can promote the healing of tendon-bone interface after rotator cuff tears. These exosomes can improve extracellular matrix remodeling, osteogenic differentiation, angiogenesis, and stemness of tendon-derived stem cells (TDSCs). The exosomes from young BMSCs have better effects compared to those from aged BMSCs.