Article
Veterinary Sciences
Judit Kis, Laszlo Rozsa, Ferenc Husveth, David Mezoszentgyorgyi, Szilvia Kovacs, Zoltan Bakos, Attila Zsolnai, Istvan Anton
Summary: The objective of this study is to investigate the association between myostatin genotypes and muscular development and cardiac variables in Thoroughbreds. The results showed significant differences in muscle fiber composition and cardiac variables between different genotypes. This study suggests a correlation between genotypes and muscular development and cardiac function.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Genetics & Heredity
Aleksandra Bojarczuk, Eugenia A. Boulygina, Magdalena Dzitkowska-Zabielska, Beata Lubkowska, Agata Leonska-Duniec, Emiliya S. Egorova, Ekaterina A. Semenova, Liliya B. Andryushchenko, Andrey K. Larin, Edward Generozov, Ildus I. Ahmetov, Pawel Cieszczyk
Summary: This study identified a rare T allele in the ACSL1 gene associated with higher fat loss efficiency in untrained women during aerobic training and lower BMI in male athletes.
Article
Medicine, Research & Experimental
Ching-Lung Ko, Wei-Zhi Lin, Meng-Ting Lee, Yu-Tien Chang, Hung-Che Lin, Yi-Syuan Wu, Jun-Fu Lin, Ke-Ting Pan, Yu-Chuan Chang, Ko-Han Lee, Yi-Lun Lee, Tsung-Ting Hsieh, Jia-Hsin Huang, Chih-Hung Wang, Sung-Sen Yang, Hsiang-Cheng Chen, Chi-Ming Chu
Summary: This study explored the race-specific SNP susceptibility of AS in Taiwanese individuals and found an association between HLA-B27 and AS susceptibility SNPs. The study also found differences in AS SNPs between Taiwanese individuals and other races, and that Taiwanese individuals with HLA-B27 positivity had a higher proportion of minor alleles. Additionally, AS polygenic risk score models were developed and individuals with high polygenic risk had a fivefold increased risk of developing AS.
JOURNAL OF TRANSLATIONAL MEDICINE
(2022)
Article
Genetics & Heredity
Jakaria Jakaria, Wenny Ladhunka Nur Aliyya, Riyadi Ismail, Sri Yuni Siswanti, Mokhamad Fakhrul Ulum, Rudy Priyanto
Summary: This study investigated single-nucleotide polymorphisms (SNPs) and 11-bp deletions in the coding region of the MSTN gene in Belgian Blue, Peranakan Ongole, and their crossbred cattle. Although four SNPs and an 11-bp deletion were found, they were not able to differentiate between normal and double-muscled phenotypes accurately.
Article
Plant Sciences
Narayana Bhat Devate, Hari Krishna, Sunil Kumar V. Parmeshwarappa, Karthik Kumar Manjunath, Divya Chauhan, Shweta Singh, Jang Bahadur Singh, Monu Kumar, Ravindra Patil, Hanif Khan, Neelu Jain, Gyanendra Pratap Singh, Pradeep Kumar Singh
Summary: This study conducted a genome-wide association study to identify markers associated with traits under heat and drought stress in bread wheat. The results provide valuable markers that can be used for marker-assisted breeding to develop climate-resilient cultivars.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Wenxin Li, Xiaojuan Wang, Xiaoxue Zhang, Fadi Li, Deyin Zhang, Xiaolong Li, Yukun Zhang, Yuan Zhao, Liming Zhao, Dan Xu, Jiangbo Cheng, Jianghui Wang, Bubo Zhou, Changchun Lin, Weimin Wang
Summary: Small ruminants farming is crucial for the livelihood of a significant portion of the population. This study investigates the impact of single nucleotide polymorphisms in the PRKAA2 gene on growth-related traits in Hu sheep and Dorper sheep. Analysis of 1254 sheep's body weight and body type data collected at various time points revealed a significant association between a PRKAA2 gene polymorphism and sheep growth traits. The highest expression of the PRKAA2 gene was observed in the spleen, followed by the kidney. This research suggests that the PRKAA2 gene could be utilized as a marker-assisted selection to enhance growth-related traits in sheep.
ANIMAL BIOTECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Eun-Ju Ko, Ji-Eun Shin, Jung-Yong Lee, Chang-Soo Ryu, Ji-Young Hwang, Young-Ran Kim, Eun-Hee Ahn, Ji-Hyang Kim, Nam-Keun Kim
Summary: Recurrent implantation failure (RIF) refers to multiple unsuccessful in vitro fertilization embryo transfers in the same individual. Genetic factors, including SNPs in FSHR, INHA, ESR1, and BMP15, have been found to be associated with RIF development in Korean women.
Article
Biochemistry & Molecular Biology
Lizhen Li, Jinlan Rao, Jingjing Lan, Yan Zhu, Aimei Gong, Liepeng Chu, Fei Feng, Chao Xue
Summary: This study aimed to investigate the association between AKT1 single nucleotide polymorphisms (SNPs) and the risk of microscopic polyangiitis (MPA) in Guangxi, China. Genotypes of 8 loci in AKT1 were evaluated in 416 individuals, including 208 MPA patients and 208 healthy volunteers. The study found that three AKT1 loci (rs2498786, rs2494752, and rs5811155) were associated with MPA risk, and a specific haplotype (G-G-T) was negatively associated with MPA risk. These findings suggest that further studies on the role of AKT1 are needed to identify intervention targets for MPA/AAV.
MOLECULAR GENETICS AND GENOMICS
(2023)
Article
Genetics & Heredity
Ricardo Omar Cadena-Lopez, Lourdes Vanessa Hernandez-Rodriguez, Adriana Aguilar-Galarza, Willebaldo Garcia-Munoz, Lorenza Haddad-Talancon, Ma de Lourdes Anzures-Cortes, Claudia Velazquez-Sanchez, Karla Lucero Flores-Viveros, Miriam Aracely Anaya-Loyola, Teresa Garcia-Gasca, Victor Manuel Rodriguez-Garcia, Ulisses Moreno-Celis
Summary: This study describes the associations between SNPs in leptin pathway genes and clinical markers related to obesity in a Mexican population, revealing both positive and negative interactions.
Article
Nutrition & Dietetics
Yuqian Li, Xiaotian Liu, Runqi Tu, Jian Hou, Guihua Zhuang
Summary: This study aims to evaluate the causal association between SOCS3 methylation and abdominal obesity. Through a case-control study on Chinese subjects, it was found that SOCS3 methylation levels were inversely associated with abdominal obesity, and the causal relationship was confirmed using Mendelian randomization.
Article
Immunology
Yan Li, Wei Li, Li Huang, Huijia Li, Peipeng He, Chao Xue
Summary: This study investigated the association between microscopic polyangiitis and the single nucleotide polymorphism rs807185 in autophagy-associated gene 4A (ATG4A) in the Chinese population. Using multiplex polymerase chain reaction and high-throughput sequencing, it was found that the control group had a higher frequency of the A allele of rs807185 compared to the microscopic polyangiitis group, suggesting that the A allele of rs807185 may have a protective effect against microscopic polyangiitis in the Chinese population. However, the molecular mechanisms remain unclear.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Jiangbo Cheng, Xiaoxue Zhang, Fadi Li, Lvfeng Yuan, Deyin Zhang, Yukun Zhang, Qizhi Song, Xiaolong Li, Yuan Zhao, Dan Xu, Liming Zhao, Wenxin Li, Jianghui Wang, Bubo Zhou, Changchun Lin, Xiaobin Yang, Weimin Wang
Summary: This study detected single nucleotide polymorphisms in MEF2B and UCP3 genes and analyzed their association with sheep growth traits. Different genotypes of the genes showed significant differences in sheep growth traits. The polymorphisms identified in MEF2B and UCP3 can serve as molecular markers for sheep growth traits.
DNA AND CELL BIOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Farah Asa'ad, Natalia Petrenya, Birgitta Joensson, Gro Eirin Holde, Nils Oscarson, Elin Hadler-Olsen, Alexandre R. Vieira, Max Petzold, Lena Larsson
Summary: This study investigated the association between periodontitis and four single nucleotide polymorphisms (SNPs) in genes related to DNA methylation, as well as the association between these SNPs and tooth loss, hs-CRP, and HbA1c levels. The results showed that there were associations between polymorphism in genes related to DNA methylation and periodontitis, tooth loss, low-grade inflammation, and hyperglycemia in this Norwegian population.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Dermatology
Yimeng Gao, Hongzhong Jin
Summary: Livedoid vasculopathy (LV) is considered a disease of hypercoagulability, and its association with genetic variants has been poorly characterised. This study systematically reviewed variants in LV patients and found that certain genetic variations may be more common in specific geographic regions or ethnicities. Large-scale case-control studies are needed to further clarify these associations.
INTERNATIONAL WOUND JOURNAL
(2021)
Article
Agriculture, Dairy & Animal Science
Satish Kumar, Subodh Kumar, Ran Vir Singh, Anuj Chauhan, Amit Kumar, Jaya Bharati, Shoor Vir Singh
Summary: This study investigated the association between SNPs in the CD209 gene and bovine PTB disease caused by MAP in Indian cattle. A significant correlation was found between SNP rs208814257 and PTB susceptibility, with the CG genotype being significantly higher in the control population, suggesting resistance against PTB.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Chemistry, Applied
Qiang Wei, Wenbin Huang, Xiaodong Liu, Anqi Li, Pengfei Zhang, Zhusong Xu, Zhiqing Yu, Xiaohan Wang, Haoran Liu, Yasong Zhou
Summary: A series of Re modified NiMo/Al2O3 hydrodesulfurization (HDS) catalysts with different contents of Re2O7 were synthesized using stepwise impregnation and co-impregnation methods. The effects of Re modification and impregnation methods on the catalysts' physical-chemical properties were characterized. The results revealed that Re modification improved the crystal morphologies, pore structures, and acid sites of the catalysts. Furthermore, the HDS evaluation showed that Re modification effectively enhanced the conversions, route selectivity, and even selectivity towards 3,3'-DMCHB of 4,6DMDBT, with the stepwise impregnation method exhibiting a more significant effect compared to co-impregnation.
Article
Engineering, Industrial
Jingru Wang, Kuanyun Zhu, Jiawu Peng, Wenyan Zhuo
Summary: This study considers a two-echelon supply chain with partial cross ownership (PCO) and explores the strategy of the retailer to share private demand information with the supplier via cheap talk. We find that when the proportion of partial cross holding shares is moderate, the retailer can truthfully disclose private demand information, benefiting both the retailer and the supplier.
INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH
(2023)
Article
Psychology, Developmental
Jiaqi Zhao, Yuanyuan An, Xiaohui Li, Jiali Huang
Summary: This study investigates the trajectories of posttraumatic growth (PTG) among adolescents who survived the Yancheng tornado in China and examines the effects of posttraumatic stress symptoms (PTSS) on these trajectories. The results reveal differentiated PTG trajectories and highlight the importance of PTSS in shaping these trajectories for improving post-disaster psychological interventions.
CHILD PSYCHIATRY & HUMAN DEVELOPMENT
(2023)
Article
Peripheral Vascular Disease
Ting Wang, Fangfang Fan, Yanjun Gong, Lan Gao, Zhihao Liu, Jia Jia, Mengyuan Liu, Yimeng Jiang, Yan Zhang, Jianping Li
Summary: This study investigated the association between albuminuria and brachial-ankle pulse wave velocity (baPWV) and carotid-femoral pulse wave velocity (cfPWV) in a community-based population in Beijing. The results showed that baPWV was significantly associated with albuminuria, and it could be considered for community health screening.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Business
Jiebing Wu, Yan Yuan, Bin Guo
Summary: This study examines the impact of cognitive proximity and technological regime on knowledge accumulation in industrial clusters. The results indicate that cognitive proximity and cumulativeness condition jointly have a significant effect on a cluster's knowledge accumulation. Moreover, large firm clusters perform best under high levels of knowledge cumulativeness.
ASIAN JOURNAL OF TECHNOLOGY INNOVATION
(2023)
Article
Otorhinolaryngology
Xiaofan Jing, Ming Yang, Yuan Liu, Yan Wang, Jingjing Li, Wen Hu
Summary: This study investigated the possible associations of chest CT-determined trunk muscle mass and quality with dysphagia in older inpatients. The results demonstrated that muscle mass was negatively associated with dysphagia, while intermuscular adipose tissue and its percentage were positively associated with dysphagia. However, muscle density was not significantly associated with dysphagia.
Article
Chemistry, Physical
Ge Yang, Yali Xie, Yaru Wang, Ying Tang, Leng Leng Chng, Fuyi Jiang, Fanglin Du, Xianfeng Zhou, Jackie Y. Ying, Xun Yuan
Summary: This paper reports on the design of a novel Cu-based nanocatalyst, watersoluble thiolated Cu-30 nanoclusters (NCs), for living cell labeling via CuAAC. The Cu-30 NCs exhibit good biocompatibility, excellent stability, and scalable synthesis, making them a promising catalyst for potential commercial applications. Furthermore, the Cu-30 NCs demonstrate superior catalytic activities for a series of Huisgen cycloaddition reactions with good recyclability, making them suitable for intracellular bioorthogonal applications.
Article
Chemistry, Multidisciplinary
Yugang Zhang, Linwei He, Tingting Pan, Jian Xie, Fuqi Wu, Xinglong Dong, Xia Wang, Lixi Chen, Shicheng Gong, Wei Liu, Litao Kang, Junchang Chen, Lanhua Chen, Long Chen, Yu Han, Shuao Wang
Summary: SCU-SnS, an open metal-sulfide framework with three different types of active sites, exhibits superior iodine adsorption capacity through mechanisms such as charge balancing and strong binding affinity.
Article
Materials Science, Ceramics
Chaoyu Li, Fafeng Xia, Liming Yao, Huaxing Li, Xin Jia
Summary: In this study, Ni and Ni-BN-TiC layers were fabricated using laser cladding technique (LCT). The microstructure, phase structure, mechanical properties, thermal stability, and corrosion behaviors of Ni-BN-TiC layers were investigated. The results showed that Ni-BN-TiC layers had a fine and compact microstructure with improved mechanical properties and outstanding corrosion resistance.
CERAMICS INTERNATIONAL
(2023)
Article
Cardiac & Cardiovascular Systems
Junyu Pei, Hao Zhang, Yanan Li, Jiafu Yan, Keyang Zheng, Xiaopu Wang, Xi-Long Zheng, Xinqun Hu
Summary: The study found a U-shaped relationship between orthostatic blood pressure changes and major adverse cardiovascular events (MACE) occurrence. An increase in orthostatic diastolic blood pressure and a decrease in orthostatic systolic blood pressure were associated with an increased MACE risk. The benefits of intensive blood pressure management were consistent across different ranges of orthostatic blood pressure changes.
Proceedings Paper
Engineering, Electrical & Electronic
Qingcheng Zhu, Yongli Zhao, Xiaosong Yu, Jie Zhang
Summary: Cloud services relying on communication, computing, and caching resources are supported by datacenter networks (DCNs). The security of these services is under threat due to the emergence of quantum computers. Quantum key distribution (QKD) technology offers information-theoretically secure secret key sharing between remote users. A quantum cloud, achieved through QKD-secured cloud datacenter networks, provides communication, computing, caching, and cipher resources for data transmission, processing, storing, and encryption. To address the coordination problem of the newly emerged 4C resources, a 4C-oriented control architecture is designed, and innovative heuristic algorithms for securing service function chains are proposed. Simulation results demonstrate that the proposed algorithms outperform the baseline in terms of service success ratio.
2023 INTERNATIONAL CONFERENCE ON OPTICAL NETWORK DESIGN AND MODELING, ONDM
(2023)
Article
Metallurgy & Metallurgical Engineering
Xiong Tianying, Wang Jiqiang
Summary: Cold spray is a rapidly developing solid-material deposition technology that has broad application prospects in areas of metal coating preparation, additive manufacturing, and component repair due to its low spraying temperature and high particle velocity.
ACTA METALLURGICA SINICA
(2023)
Article
Mathematics, Applied
Zimo Yan, Xie Zheng, Jianping Li
Summary: In this paper, the relationships between some vertex-degree-based topological indices (including the general Randic index, the first Zagreb index, and the forgotten index) and the energy of graphs are established by using the concept of the energy of a vertex. Bounds on the energy of graphs containing no isolated vertices are given in terms of the first Zagreb index and the forgotten index. Furthermore, bounds on the normalized Laplacian energy in terms of two particular cases of the general Randic index are obtained.
DISCRETE MATHEMATICS LETTERS
(2023)
Review
Multidisciplinary Sciences
Ke Tian Tan, Samrat Ghosh, Zhiyong Wang, Fuxiang Wen, David Rodriguez-San-Miguel, Jie Feng, Ning Huang, Wei Wang, Felix Zamora, Xinliang Feng, Arne Thomas, Donglin Jiang
Summary: Chemical approaches play a crucial role in the design, synthesis, control and engineering of small molecules, polymers and networks, combining covalent bonds and non-covalent interactions to establish complex structures for specific functions. Covalent organic frameworks (COFs) are crystalline porous polymers that integrate organic units into highly ordered structures through polymerization using covalent bonds for primary order structures and non-covalent interactions for high order structures in a one-pot reaction system. This Primer provides a comprehensive overview of the field of COFs, covering chemistry, physics, materials and applications, aiming to present a concise yet complete picture of the field and addressing key fundamental issues with future directions in mind.
NATURE REVIEWS METHODS PRIMERS
(2023)
Article
Green & Sustainable Science & Technology
Yonggan Yang, Zihao Kang, Binggen Zhan, Peng Gao, Qijun Yu, Yanlai Xiong, Jingfeng Wang, Yunsheng Zhang
Summary: This paper systematically studied the effects of different mineral admixtures and sulfate solution types on the performance of concrete, and explored the changes in the microstructure and corrosion products of concrete using various analysis methods. The results showed that the presence of magnesium ions accelerated concrete deterioration, while an appropriate amount of slag improved the corrosion resistance of concrete.
JOURNAL OF RENEWABLE MATERIALS
(2023)
Article
Genetics & Heredity
Xiangge Meng, Chengping Li, Yu Hei, Xiang Zhou, Guoli Zhou
Summary: The study used IVT-SAPAS sequencing to analyze the dynamic changes of APA sites during adipogenesis in bovine subcutaneous preadipocytes and intramuscular preadipocytes. The results showed that APA plays an important role in adipocyte differentiation, and UTR-APA switching genes have different trends, with intramuscular preadipocytes tending to use shorter 3'UTR for differentiation. TRIB3, WWTR1, and INSIG1 play important roles in intramuscular preadipocyte differentiation.
Article
Genetics & Heredity
S. Alizadeh, S. Khamse, N. Tajeddin, H. R. Khorram Khorshid, A. Delbari, M. Ohadi
Summary: This study identifies a specific genotype at a CG-rich trinucleotide short tandem repeat (STR) locus that is associated with late-onset neurocognitive disorders such as Alzheimer's disease (AD).
Article
Genetics & Heredity
Shougang Liu, Zhe Zhuang, Fanghua Liu, Xiuqing Yuan, Zeqiao Zhang, Xiaoqian Liang, Xinhui Li, Yongfeng Chen
Summary: This study investigated the effect and mechanism of RPL9 and TIFA in scalp psoriasis, and identified RPL9 as a potential therapeutic target for scalp psoriasis.
Article
Genetics & Heredity
Shiting Wang, Jiaqi Chen, Zhichao Jin, Ying Xing, Ruiping Wang
Summary: This study suggests a causal association between hair color and skin cancers, with light hair colors (red, blonde, and light brown) being associated with an increased risk and dark brown hair being associated with a decreased risk.
Article
Genetics & Heredity
Joseph Hawadak, Loick Pradel Kojom Foko, Rodrigue Roman Dongang Nana, Karmveer Yadav, Veena Pande, Aparup Das, Vineeta Singh
Summary: This study investigates the genetic diversity and natural selection of the Pfama-1 gene in Plasmodium falciparum isolates from Cameroon. The study finds a considerable nucleotide and haplotype diversity, as well as specific mutations in Cameroonian isolates. Positive diversifying selection and the identification of selected codon sites suggest the potential implication of these genetic variations in host immune pressure and parasite-binding complex modulation. The findings provide valuable baseline data for malaria vaccine design.
Article
Genetics & Heredity
Emily Biernat, Mansi Verma, Chhabi K. Govind
Summary: RSC is an essential ATP-dependent chromatin remodeling complex in Saccharomyces cerevisiae. It regulates nucleosome-depleted regions (NDRs) by sliding flanking nucleosomes away from NDRs. Depletion of RSC leads to nucleosome encroachment in NDRs and transcription initiation defects. The study compared the effects of catalytic-dead Sth1 and rapid depletion of Sth1 on transcription. Rapid depletion of Sth1 reduces recruitment of TBP and Pol II, while the catalytic-dead mutant exhibits a severe reduction in TBP binding but accumulates Pol II in coding regions. The results suggest a role for RSC in transcription elongation and termination processes.
Article
Genetics & Heredity
Yunxiao Wei, Yuhan Song, Muhammad Aamir Khan, Chengzhen Liang, Zhigang Meng, Yuan Wang, Sandui Guo, Rui Zhang
Summary: This study analyzed the GhTPP protein family in upland cotton for the first time and identified the important role of GhTPPA_2 in regulating sugar metabolism, improving soluble sugar accumulation, and drought stress tolerance.
Article
Genetics & Heredity
Yannan Geng, Rui Shao, Tiantong Xu, Lilong Zhang
Summary: A novel risk model based on SCUBE3, TNNC1, SPON1, SEPT12 and ULBP1 genes was developed for predicting PMOP risk, with higher risk score indicating higher risk of suffering from PMOP. Significant differences in signaling pathway activities were observed between the high-risk score group and the low-risk score group.
Article
Genetics & Heredity
Randy P. Williams, Corina Lesseur, Haoxiang Cheng, Qian Li, Maya Deyssenroth, Christopher D. Molteno, Ernesta M. Meintjes, Sandra W. Jacobson, Joseph L. Jacobson, Helen Wainwright, Ke Hao, Jia Chen, R. Colin Carter
Summary: The study suggests that heavy alcohol exposure during pregnancy may impact the proportion of fetal placental villi macrophages and increase the expression of inflammatory genes. Further research is needed to explore these effects and evaluate the potential functional roles of placental inflammation in FASD.
Article
Genetics & Heredity
Lvjing Luo, Lishuang Sun, Shu Li, Huiting Liu, Zhengyu Chen, Shi Huang, Yinyin Mo, Genliang Li
Summary: This study analyzed the expression of Ptpn1 and miR-124-3p in testicular tissues of mice and investigated their regulatory relationship. The results showed that Ptpn1 expression was up-regulated in adult mouse testis compared to juvenile mouse testis, while miR-124-3p expression showed an opposite pattern. Further analysis suggested that the down-regulation of miR-124-3p may contribute to the high expression of Ptpn1 in adult mouse testis.
Article
Genetics & Heredity
Gairui Li, Dan Zhao, Xiaolin Peng, Yashuang Zhao
Summary: MiRNA-22 shows potential as a candidate for early diagnosis of colorectal cancer (CRC). The study found higher miR-22 expression levels in the CRC and CRA groups, suggesting its potential as a biomarker for CRC early screening.
Article
Genetics & Heredity
Zhongqiu Zhu, Qianting Yang, Xiaoying Tian, Da Man, Jian Wang, Junfang Zhang, Bingshe Han
Summary: This study constructed a ceRNA network mediated by lncRNAs in cold-acclimated zebrafish ZF4 cells and revealed that upregulation of MSTRG3207 promotes apoptosis by sponging dre-miR-736 during cold acclimation.
Article
Genetics & Heredity
Weitao Chen, Denggao Xiang, Shang Gao, Shuli Zhu, Zhi Wu, Yuefei Li, Jie Li
Summary: Dam construction has negatively impacted the genetic diversity and structure of fish populations. This case study on the endangered Hemibagrus guttatus found low genetic diversity, high levels of inbreeding, and decreasing population size in fragmented populations. Genetic structure and differentiation were also observed, indicating the influence of dams on these fish populations.
Article
Genetics & Heredity
Pooja Singh, Debleena Guin, Bijay Pattnaik, Ritushree Kukreti
Summary: Through systematic literature review and meta-analysis, it was found that idiopathic pulmonary fibrosis is significantly associated with 222 polymorphisms in 118 genes. Four polymorphisms - rs35705950/MUC5B, rs2736100/TERT, rs2076295/DSP, and rs111521887/TOLLIP, exhibited substantial epidemiological evidence supporting their association with IPF risk.
Article
Genetics & Heredity
Jianping Zhang, Zhijun Cai, Fanzhe Feng, Yufeng Peng, Yi Cui, Yongiqing Xu
Summary: This study found that exosomes secreted by young BMSCs can promote the healing of tendon-bone interface after rotator cuff tears. These exosomes can improve extracellular matrix remodeling, osteogenic differentiation, angiogenesis, and stemness of tendon-derived stem cells (TDSCs). The exosomes from young BMSCs have better effects compared to those from aged BMSCs.
