期刊
GENE
卷 485, 期 1, 页码 16-21出版社
ELSEVIER
DOI: 10.1016/j.gene.2011.05.029
关键词
Olfactory receptor; Salmonid; Positive selection
资金
- Oregon Watershed Enhancement Board
Salmon utilize olfactory cues to guide natal stream homing during spawning migrations. Both inorganic and biogenic chemicals have been proposed as odorants that might be used by salmon during homing. In this study, we used genomic DNA sequence data from nine salmonid species to compare nucleotide identities for orthologous main olfactory receptor (mOR) genes with nucleotide identities for orthologous vomeronasal type 1-like (ora) receptor genes. We found that orthologs for both classes of olfactory receptor genes (mORs and Oras) appear to be highly conserved among species. Our findings do not support the differential tuning hypothesis in Salmonidae, which predicts higher sequence conservation for mORs than ora. We did, however, find convincing evidence for site-specific positive selection acting on paralogous main olfactory receptor genes. (C) 2011 Elsevier B.V. All rights reserved.
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