Article
Multidisciplinary Sciences
Andre J. McDonald, Hayley A. Hamilton, Tara Elton-Marshall, Yeshambel T. Nigatu, Damian Jankowicz, Susan J. Bondy, Samantha Wells, Christine M. Wickens
Summary: This study examines the association between household composition and anxiety symptoms during the COVID-19 pandemic, with a focus on gender as an effect modifier. The results show that single parents/guardians, individuals living with adults and children, and those living with adults only have a higher risk of anxiety symptoms compared to those living alone. Gender plays a significant role as an effect modifier, with the association between living with children and anxiety symptoms being stronger for men than women.
Article
Clinical Neurology
Min Xu, Adriana Amarilla Vallejo, Clara Cantalapiedra Calvet, Anthony Rudd, Charles Wolfe, Matthew D. L. O'Connell, Abdel Douiri
Summary: Female stroke patients have lower adjusted risk of death and stroke recurrence or death compared to male patients. However, they have poorer outcomes in terms of activities of daily living, anxiety, and health-related quality of life, which persist up to 5 years after stroke.
Article
Obstetrics & Gynecology
Anne H. Thomsen, Anne Gaml-Sorensen, Nis Brix, Andreas Ernst, Lea L. H. Lunddorf, Katrine Strandberg-Larsen, Astrid Hojgaard, Cecilia H. Ramlau-Hansen
Summary: This study found that adolescents who reported gender incongruence tended to reach puberty slightly earlier than those who reported gender congruence.
FERTILITY AND STERILITY
(2022)
Article
Clinical Neurology
Julia Aivo, Jori O. Ruuskanen, Aleksi Tornio, Paivi Rautava, Ville Kyto
Summary: This study found that not using statins after ischemic stroke is associated with adverse long-term outcomes, such as increased all-cause mortality and higher risk of cardiovascular events. Measures to improve timely statin use after stroke are needed.
Article
Clinical Neurology
Kuan-Ying Li, Mei-Chia Chou, James Cheng-Chung Wei, Mei-Chen Lin, Yao-Min Hung, Renin Chang
Summary: This study found an increased risk of stroke, particularly hemorrhagic stroke, among patients with leptospirosis. The risk was higher for males and individuals aged 18 to 39, with the highest risk in the first two years after diagnosis. Age served as an effect modifier in the association between leptospirosis and new-onset stroke risk.
Article
Health Care Sciences & Services
Wen-Jun Tu, Yang Hua, Feng Yan, Hetao Bian, Yi Yang, Min Lou, Dezhi Kang, Li He, Lan Chu, Jingsheng Zeng, Jian Wu, Huisheng Chen, Jianfeng Han, Lin Ma, Lei Cao, Longde Wang
Summary: The prevalence of stroke in China has been increasing over the past 7 years, particularly among males, older individuals, and those residing in rural and northeast areas. These findings are important for improving stroke prevention and addressing related risk factors.
LANCET REGIONAL HEALTH-WESTERN PACIFIC
(2022)
Article
Clinical Neurology
Joseph Aked, Hossein Delavaran, Arne G. Lindgren
Summary: The study aimed to provide up-to-date population-based information on long-term survival, causes of death, and recurrence after stroke. The results showed relatively high stroke survival rates, with a potential slowdown in improvement over recent decades. The common occurrence of changed pathogenetic mechanisms between first-ever and recurrent stroke highlights the value of reassessment in recurrent stroke.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Clinical Neurology
Kye Won Park, Eun-Jae Lee, Jun Seong Lee, Jinhoon Jeong, Nari Choi, Sungyang Jo, Mina Jung, Ja Yeon Do, Dong-Wha Kang, June-Goo Lee, Sun Ju Chung
Summary: Machine learning-based algorithms for automated rating of Parkinson's disease symptoms show very good reliability compared to ratings by nontrained human raters, providing Class II evidence in support of their feasibility.
Article
Cardiac & Cardiovascular Systems
Asos Mahmood, Meredith Ray, Aram Dobalian, Kenneth D. Ward, SangNam Ahn
Summary: The study found an association between insomnia symptoms and incident heart failure, indicating the need for increased public health awareness and screening for insomnia symptoms in order to reduce the incidence of heart failure.
EUROPEAN HEART JOURNAL
(2021)
Article
Multidisciplinary Sciences
Erla S. Siguroardottir, Thorarinn Gislason, Bryndis Benediktsdottir, Steinar Hustad, Payam Dadvand, Pascal Demoly, Karl A. Franklin, Joachim Heinrich, Mathias Holm, Diana A. van der Plaat, Rain Jogi, Benedicte Leynaert, Eva Lindberg, Jesus Martinez-Moratalla, Leire Sainz De Aja, Giancarlo Pesce, Isabelle Pin, Chantal Raherison, Antonio Pereira-Vega, Francisco Gomez Real, Kai Triebner
Summary: The prevalence of obstructive sleep apnea is higher in women after menopause, possibly due to altered sex hormone balance. Middle-aged women with lower serum estrogen and progesterone levels are more likely to experience symptoms of obstructive sleep apnea.
Article
Psychology, Clinical
Alvin Richards-Belle, Norman Poole, David P. J. Osborn, Vaughan Bell
Summary: This study aimed to estimate longitudinal associations between stroke and psychosis over 10 years. The results showed that stroke is an independent predictor of psychosis, and vice versa.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Akihiko Iwasa, Eiji Tanaka
Summary: This study investigates the causes and symptoms of idiopathic condylar resorption (ICR) in orthodontic patients. The results suggest that ICR may be caused by a combination of intrinsic and extrinsic factors. It is also recommended to perform CT evaluation for patients suspected of having ICR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Husameldin Elsawi Khalafalla, Bushra Ahmed Alfaifi, Ruwaym Jaber Alharbi, Shahd Othman Almarei, Taif Ahmed Kobal, Halimah Najea Alsomaili, Shatha Ahmed Drbshi, Shareefa Ahmed Sumayli, Amal Ahmed Kamili, Alanoud Mohammed Masmali
Summary: This study assessed awareness of stroke signs, symptoms, and risk factors among university students in the southern region of Saudi Arabia. While the participants showed good knowledge levels, there is still room for improvement in awareness.
Article
Geriatrics & Gerontology
Jingyang Hu, Xinyu Zheng, Guangduoji Shi, Lan Guo
Summary: The study found independent associations between multiple chronic diseases and depressive symptoms with incident stroke, and showed that middle-aged and elderly adults with both multiple chronic diseases and depressive symptoms had a higher risk of stroke.
Review
Clinical Neurology
Silke Walter, Daniel Phillips, Brittany Wells, Robert Moon, Thomas Bertsch, Iris Q. Grunwald, Klaus Fassbender
Summary: Despite the challenges, prehospital stroke management plays a crucial role in ensuring equal access to specialized stroke care. Gender differences exist in the detection, dispatch, and delivery of stroke patients, and addressing these differences is essential for improving stroke outcomes.
FRONTIERS IN NEUROLOGY
(2022)
Article
Health Care Sciences & Services
William P. Cheshire, Kevin M. Barrett, Benjamin H. Eidelman, Elizabeth A. Mauricio, Josephine F. Huang, William D. Freeman, Maisha T. Robinson, Gary R. Salomon, Colleen T. Ball, Dale M. Gamble, Vickie S. Melton, James F. Meschia
Summary: This study found no significant difference in patient perceptions of physician empathy between telemedicine and in-person consultations for acute stroke care, indicating that empathy can be effectively conveyed through telemedicine encounters without physical touch or proximity.
JOURNAL OF TELEMEDICINE AND TELECARE
(2021)
Article
Pharmacology & Pharmacy
Courtney L. James, Marion T. Turnbull, William D. Freeman
Article
Neurosciences
Kaneez Zahra, Marion T. Turnbull, Abba C. Zubair, Jason L. Siegel, Carla P. Venegas-Borsellino, Rabih G. Tawk, William D. Freeman
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2020)
Editorial Material
Clinical Neurology
W. David Freeman, Peter L. Carlen
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2021)
Article
Medicine, General & Internal
Johan L. Heemskerk, Ricardo A. Domingo, Rabih G. Tawk, Tito G. Vivas-Buitrago, Josephine F. Huang, Ashley Rogers, Alfredo Quinones-Hinojosa, Kingsley Abode-Iyamah, William D. Freeman
Summary: This study analyzed prehospital time for patients with suspected stroke transported to treatment centers in Florida in 2018, finding that dispatch notification and stroke assessment scales can reduce EMS time. Adoption of these interventions may improve stroke systems of care.
MAYO CLINIC PROCEEDINGS
(2021)
Review
Medicine, General & Internal
Cumara B. O'Carroll, Benjamin L. Brown, W. David Freeman
Summary: Spontaneous intracerebral hemorrhage is a medical emergency associated with chronic hypertension and vessel rupture, with treatment strategies focusing on timely diagnosis, aggressive blood pressure control, correction of coagulopathy defects, treatment of cerebral edema, and assessment for surgical intervention.
MAYO CLINIC PROCEEDINGS
(2021)
Review
Medicine, General & Internal
Rabih G. Tawk, Tasneem F. Hasan, Caitlin E. D'Souza, Jeffrey B. Peel, William D. Freeman
Summary: Unruptured intracranial aneurysms are common vascular lesions that can lead to severe consequences. While previous consensus indicated that small aneurysms (<7 mm) are less likely to rupture, current research highlights the importance of considering other risk factors.
MAYO CLINIC PROCEEDINGS
(2021)
Article
Health Care Sciences & Services
Stephen W. English, Kevin M. Barrett, Willam D. Freeman, Bart M. Demaerschalk
Summary: The recognition and management of stroke in the prehospital setting has become more important, with strategies like the mobile stroke unit and telemedicine-enabled ambulance being developed. These strategies differ in costs, scalability, integration, and interoperability, aiming to guide prehospital leaders to find the most suitable solutions for their communities.
JOURNAL OF TELEMEDICINE AND TELECARE
(2022)
Article
Clinical Neurology
W. David Freeman, Ashley Rogers, Alejandro Rabinstein
Summary: This review summarizes the current state, emerging research, and new technologies of TeleNeuroICU, and discusses the value and future development of TeleNeuroICU in healthcare systems.
SEMINARS IN NEUROLOGY
(2022)
Editorial Material
Critical Care Medicine
W. David Freeman
NEUROCRITICAL CARE
(2022)
Article
Clinical Neurology
Stephen W. English, Kevin M. Barrett, William D. Freeman, Bart M. Demaerschalk, Oana M. Dumitrascu
Summary: This article discusses the importance of diagnosing and managing acute vision loss, highlighting the limitations of remote healthcare services and the impact of the COVID-19 pandemic on ophthalmological diagnosis. The authors propose new approaches to improve remote ophthalmological evaluation and enhance acute ophthalmological care.
Editorial Material
Immunology
Amra Sakusic, Baibing Chen, Kimberly McPhearson, Mohammed Badi, William D. Freeman, Josephine F. Huang, Jason L. Siegel, Mark E. Jentoft, Justin M. Oring, Jorge Verdecia, James F. Meschia
Summary: This case presents a 61-year-old woman with a history of orthotopic heart transplant who was hospitalized with new-onset headache. MRI of the brain revealed left occipital lobe involvement and mild vasogenic edema. The patient developed neurological symptoms and was found to have a rare amoeba infection, Balamuthia mandrillaris, leading to her death despite treatment efforts.
OPEN FORUM INFECTIOUS DISEASES
(2023)
Article
Health Care Sciences & Services
Kaneez Zahra, Ricardo A. Domingo, Marion T. Turnbull, Christan D. Santos, Sarah H. Peacock, Daniel A. Jackson, Rabih G. Tawk, Jason L. Siegel, William David Freeman
Summary: This study reports the preliminary safety, tolerability, and utility of concentrated intraventricular nicardipine (IVN) injections in the treatment of aneurysmal subarachnoid hemorrhage (aSAH). The results suggest that concentrated IVN injection is relatively safe, tolerable, and a potential option for treating refractory vasospasm in poor-grade SAH.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Ricardo Diaz Milian, Pablo Moreno Franco, William D. Freeman, John D. Halamka
MAYO CLINIC PROCEEDINGS
(2023)
Article
Clinical Neurology
Mariam Tsikvadze, Baltazar Machado De Villafane, Mariah Rose, Sarah Peacock, Jeffrey Brent Peel, Lauren Ng, Christopher Kramer, William D. Freeman
Summary: This article describes a severe case of Susac Syndrome complicated by rapid progression of cerebral edema and eventual brain death, in order to increase awareness of this rare and catastrophic complication.