Article
Gastroenterology & Hepatology
Hyun Seok Lee, Michael V. Chiorean, Elisa Boden, James Lord, Shayan Irani, Richard Kozarek, Michael Larsen, Andrew Ross
Summary: This study found that endoscopic balloon dilation for CD-related strictures can be safely and effectively performed without fluoroscopic guidance. Factors such as balloon size, patient age, stricture location, and multiplicity have been associated with clinical success and the need to avoid surgery.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Kate E. Lee, Francesca Lim, Adam S. Faye, Bo Shen, Chin Hur
Summary: This study analyzed the cost-effectiveness of endoscopic balloon dilation (EBD) compared to resection surgery for managing Crohn's disease strictures. The results showed that EBD is a cost-effective strategy, considering patient risks and quality of life after intervention.
DIGESTIVE DISEASES AND SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Juanjuan Zhang, Yi Li, Yanqing Diao, Binlin Da, Zhiming Wang
Summary: Duodenal Crohn's disease-associated strictures can be effectively and safely treated with endoscopic balloon dilation (EBD). Serial dilations may delay recurrence and the need for surgery, but do not change long-term outcomes or prevent surgery.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Teruyuki Takeda, Masahiro Kishi, Noritaka Takatsu, Yasumichi Takada, Tsuyoshi Beppu, Masaki Miyaoka, Takashi Hisabe, Toshiharu Ueki, Hisatomi Arima, Fumihito Hirai, Kenshi Yao
Summary: The study investigated the long-term efficacy and safety of endoscopic balloon dilation (EBD) for intestinal strictures in patients with Crohn's disease (CD) receiving anti-tumor necrosis factor alpha antibodies (anti-TNF) as maintenance therapy. The results showed that EBD was an effective and safe treatment for CD patients with intestinal strictures, with 3- and 5-year cumulative surgery-free rates of 81.1% and 73.5%, respectively.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Hironori Yamamoto, Tomonori Yano, Akihiro Araki, Motohiro Esaki, Kazuo Ohtsuka, Naoki Ohmiya, Shiro Oka, Hiroshi Nakase, Shigeki Bamba, Fumihito Hirai, Naoki Hosoe, Tomoki Matsuda, Keigo Mitsui, Kenji Watanabe, Haruhiko Ogata, Shinichi Katsuki, Takayuki Matsumoto, Mitsuhiro Fujishiro, Kazuma Fujimoto, Haruhiro Inoue
Summary: This guideline provides a summary of new scientific techniques and evidence regarding endoscopic balloon dilation for the treatment of Crohn's disease-associated small intestinal strictures.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Marion Tilmant, Melanie Serrero, Florian Poullenot, Guillaume Bouguen, Benjamin Pariente, Romain Altwegg, Paul Basile, Jerome Filippi, Pierre Vanelslander, Anthony Buisson, Ariane Desjeux, David Laharie, Eric Le Balch, Maria Nachury, Lucile Boivineau, Guillaume Savoye, Xavier Hebuterne, Laurent Poincloux, Lucine Vuitton, Franck Brazier, Clara Yzet, Adnane Lamrani, Laurent Peyrin-Biroulet, Mathurin Fumery
Summary: Endoscopic balloon dilation of Crohn's disease-associated colorectal strictures is feasible, with high rates of technical and clinical success. With longer follow-up, over 40% of patients can become asymptomatic without the need for surgery.
CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY
(2021)
Article
Gastroenterology & Hepatology
Qingqing Liu, Xiaofei Zhang, Huaibin Mabel Ko, Daniel Stocker, Jordan Ellman, Joyce Chen, Yansheng Hao, Swati Bhardwaj, Yuanxin Liang, Judy Cho, Jean Frederic Colombel, Bachir Taouli, Noam Harpaz
Summary: This study identified and characterized ileal strictures in Crohn's disease, showing that it is primarily caused by mural constriction rather than fibromuscular hypertrophy. The study also found that mesenteric fat wrapping and myenteric plexitis may contribute to the pathogenesis of the strictures.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Surgery
Nan Lan, Jin-Jie Wu, Xian-Rui Wu, Tracy L. Hull, Bo Shen
Summary: This study compared the efficacy and safety of endoscopic stricturotomy and endoscopic balloon dilation in treating pouch inlet strictures. The results showed that both methods were effective with similar surgery-free survival rates, but EBD had a higher risk of perforation while stricturotomy had a higher risk of bleeding.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Jonathan Blackwell, Sonia Saxena, Nishani Jayasooriya, Irene Petersen, Matthew Hotopf, Hanna Creese, Alex Bottle, Richard C. G. Pollok
Summary: The study found that permanent stomas and temporary stomas with late reversal surgery are associated with increased use of antidepressant medication after intestinal surgery, likely linked to increased anxiety and depression.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Medicine, General & Internal
Lauren A. Beeder, Grayden S. Cook, Samantha W. Nealon, Shervin Badkhshan, Sarah C. Sanders, Dylan P. Perito, Steven J. Hudak, Allen F. Morey
Summary: Transurethral balloon dilation is a minimally invasive treatment for urethral stricture disease. The use of non-medicated balloons resulted in a recurrence rate of approximately 50%, regardless of previous treatments, radiation history, or stricture characteristics.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Partha Pal, Jaini Gala, Pradeep Rebala, Rupa Banerjee, Mohan Ramchandani, Zaheer Nabi, Swathi Kanaganti, Mahesh G. Shetty, Rajesh Gupta, Sundeep Lakhtakia, Guduru Venkat Rao, Manu Tandan, D. Nageshwar Reddy
Summary: Endotherapy for CD strictures requires more re-interventions compared with resection, although re-operation could be avoided in the majority with similar symptom-free survival at 1 year.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Gastroenterology & Hepatology
Shou-bin Ning, Hongsheng Yang, Bairong Li, Yiyang Zhang, Shuling Huang, Bo Peng, Huixian Lin, Mrigul Kurban, Miao Li, Qin Guo
Summary: This study found that balloon-assisted enteroscopy-based endoscopic stricturotomy (BAE-based ES) has high technical success, favorable clinical efficacy, and safety in deep small bowel strictures associated with Crohn's disease.
DIGESTIVE AND LIVER DISEASE
(2023)
Article
Gastroenterology & Hepatology
Yusheng Chen, Zhenya Sun, Zhun Li, Ming Duan, Yan Zhou, Yi Li, Weiming Zhu, Zhen Guo
Summary: A retrospective study compared the efficacy and safety of endoscopic balloon dilation (EBD) and surgery in the treatment of duodenal stricture in patients with Crohn's disease (CD). Surgery was associated with longer recurrence-free survival but more postprocedural adverse events. EBD was safe and effective but had a higher frequency of recurrence.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2023)
Article
Surgery
Jiankun Wang, Lili Zhao, Rui Wu, Min Wang, Li Liu, Xiang Wang, Wenjie Liu, Kexin He, Lin Miao, Zhining Fan
Summary: Benign esophageal strictures are common complications after esophageal surgery or extensive endoscopic submucosal dissection. This study retrospectively analyzed patients with such strictures and found that a 3-minute duration for endoscopic dilation was considered safe and effective for treatment.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
Review
Gastroenterology & Hepatology
Xiaoxuan Lin, Yu Wang, Zishan Liu, Sinan Lin, Jinyu Tan, Jinshen He, Fan Hu, Xiaomin Wu, Subrata Ghosh, Minhu Chen, Fen Liu, Ren Mao
Summary: Intestinal strictures, a common complication of Crohn's disease, remain difficult to treat. Current therapies, such as endoscopic balloon dilation and surgery, have high recurrence rates. The mechanisms of intestinal fibrosis are poorly understood, and there is a lack of reliable methods for evaluating it. However, new techniques like single-cell sequencing, multi-omics, and artificial intelligence are driving progress in this field.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY
(2022)
