Article
Gastroenterology & Hepatology
Anton Rajadurai, Leonardo Zorron Cheng Tao Pu, Rees Cameron, Peter Tagkalidis, Bronte Holt, Milan Bassan, Saurabh Gupta, Daniel Croagh, Michael Swan, Payal Saxena, Marios Efthymiou, Rhys Vaughan, Sujievvan Chandran
Summary: The study demonstrates that EUS-GB and EUS-BD are promising alternatives for managing acute cholecystitis and malignant biliary obstruction, with high technical success rates and acceptable clinical success rates. Further research is needed to investigate the relationship between technical and clinical success.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Surgery
Ahmed Kayal, Niloofar Taghizadeh, Takuya Ishikawa, Emmanuel Gonzalez-Moreno, Sydney Bass, Martin J. Cole, Steven J. Heitman, Rachid Mohamed, Christian Turbide, Yen- Chen, Nauzer Forbes
Summary: A retrospective study comparing clinical outcomes and adverse events by stent type found that LAMS had higher clinical success rates, lower adverse event profile, and shorter procedural time compared to FCSEMS and PS for WON. LAMS can be considered as an initial approach for WON due to its superior outcomes.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Gastroenterology & Hepatology
Dongwook Oh, Jae Hoon Lee, Tae Jun Song, Ki Byung Song, Dae Wook Hwang, Jin Hee Kim, Do Hyun Park, Sang Soo Lee, Dong-Wan Seo, Sung Koo Lee, Myung-Hwan Kim
Summary: This study evaluated the efficacy and safety of a novel lumen-apposing metal stent (LAMS) in patients with postoperative pancreatic fluid collections (POPFCs). The results showed that EUS-guided transluminal drainage (EUS-TD) with the novel LAMS was technically feasible and effective for treating symptoms of POPFCs, with an acceptable adverse event rate.
GASTROINTESTINAL ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Ryan J. Law, Vinay Chandrasekhara, Amit Bhatt, Juan Carlos Bucobo, Andrew P. Copland, Kumar Krishnan, Nikhil A. Kumta, Rahul Pannala, Mansour A. Parsi, Erik F. Rahimi, Monica Saumoy, Guru Trikudanathan, Arvind J. Trindade, Julie Yang, David R. Lichtenstein
Summary: LAMS are a novel class of endoscopic devices that were initially introduced for drainage of pancreatic pseudocysts and walled-off necrosis, but have since been used for a variety of off-label indications such as gallbladder drainage, enteric bypass, and treatment of GI strictures.
GASTROINTESTINAL ENDOSCOPY
(2021)
Article
Gastroenterology & Hepatology
Shuntaro Mukai, Takao Itoi, Takayoshi Tsuchiya, Kentaro Ishii, Reina Tanaka, Ryosuke Tonozuka, Yoshihiro Furuichi, Eri Joyama, Hideaki Miyazawa, Atsushi Sofuni
Summary: This study evaluates the feasibility of a newly designed LAMS system for interventional EUS through animal experiments. The results demonstrate successful procedures without adverse events, indicating the potential clinical value of this system for interventional EUS.
JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES
(2022)
Article
Medicine, General & Internal
Giovana Biasia de Sousa, Rodrigo Strehl Machado, Frank Shigueo Nakao, Ermelindo Della Libera
Summary: This study included 11 patients undergoing EUS-guided drainage of PPC using double-pigtail plastic stents, with a clinical success rate of 91% and a technical success rate of 100%, demonstrating high safety and efficacy.
Review
Medicine, General & Internal
Alessandro Fugazza, Marta Andreozzi, Alessandro De Marco, Leonardo Da Rio, Matteo Colombo, Marco Spadaccini, Silvia Carrara, Marco Giacchetto, Mrigya Sharma, Vincenzo Craviotto, Anita Busacca, Chiara Ferrari, Alessandro Repici
Summary: This narrative review provides an overview of the application of endoscopic ultrasound-guided biliary drainage (EUS-BD) for the treatment of malignant biliary obstruction, with a focus on EUS-guided gallbladder drainage (EUS-GBD) using lumen apposing metal stent (LAMS). EUS-BD has shown high rates of technical and clinical success, with fewer adverse events compared to percutaneous trans-hepatic biliary drainage (PTBD). It is currently considered as the preferred alternative technique for biliary drainage in patients with distal malignant biliary obstruction (DMBO) after failed endoscopic retrograde cholangiopancreatography (ERCP).
Article
Gastroenterology & Hepatology
Surinder S. S. Rana, Ravi Sharma, Gaurav Sharma, Rajesh Gupta
Summary: In this retrospective study, the safety and efficacy of replacing lumen apposing metal stents (LAMS) with long-term indwelling transmural plastic stents in patients with disconnected pancreatic duct (DPD) at head/neck of pancreas were evaluated. The results showed that long-term transmural plastic stent placement after removal of LAMS is a safe and effective strategy to prevent the recurrence of pancreatic fluid collections (PFC).
DIGESTIVE DISEASES AND SCIENCES
(2023)
Article
Gastroenterology & Hepatology
Antonio Facciorusso, Arnaldo Amato, Stefano Francesco Crino, Emanuele Sinagra, Marcello Maida, Alessandro Fugazza, Cecilia Binda, Alessandro Repici, Ilaria Tarantino, Andrea Anderloni, Carlo Fabbri
Summary: This study aimed to develop a prognostic model for adverse events (AE) after lumen-apposing metal stents (LAMS) placement in patients with pancreatic fluid collections (PFC). Through data collection and analysis, it was found that AE occurrence in PFC patients was associated with factors such as injury to the main pancreatic duct, abnormal vessels, surgical technique, and the need for preprocedural drainage. A nomogram was used to predict the probability of AE occurrence, and the model showed good discrimination and was validated internally.
DIGESTIVE ENDOSCOPY
(2022)
Article
Gastroenterology & Hepatology
Vinay Chandrasekhara, Sherif Elhanafi, Andrew C. Storm, Naoki Takahashi, Nam Ju Lee, Michael J. Levy, Karan Kaura, Lillian Wang, Shounak Majumder, Santhi S. Vege, Ryan J. Law, Barham K. Abu Dayyeh
Summary: This study found that half of patients with pancreatic fluid collections drained with lumen-apposing metal stents required step-up therapy, most commonly direct endoscopic necrosectomy. Patients with larger collections, paracolic extension, or higher solid necrosis content were more likely to need step-up therapy.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Article
Gastroenterology & Hepatology
Sergio Bazaga, Francisco Javier Garcia-Alonso, Jose Ramon Aparicio Tormo, Belen Martinez Moreno, Vicente Sanchiz, Joan B. Gornals, Carme Loras, Alvaro Teran, Enrique Vazquez-Sequeiros, Rafael Pedraza Sanz, Jose Carlos Subtil, Antonio Perez-Millan, Francisco Uceda Porta, Juan J. Vila, Carlos de la Serna-Higuera, Ignacio Couto-Worner, Carlos Guarner-Argente, Manuel Perez-Miranda
Summary: This study aimed to investigate the safety and risk factors for adverse events (AEs) of endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) with long-term indwell of lumen-apposing metal stents (LAMS). The study found that patients with pancreatobiliary malignancy had an increased risk of recurrent biliary events, while misdeployment of LAMS was the strongest risk factor for AEs.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Review
Gastroenterology & Hepatology
Elia Armellini, Flavio Metelli, Andrea Anderloni, Anna Cominardi, Giovanni Aragona, Michele Marini, Fabio Pace
Summary: LAMS misdeployment is a common adverse event in EUS-guided drainages, and there is no standardized guideline for rescue strategies. The choice of rescue approach depends on the clinical scenario, anatomical characteristics, and local expertise.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Gastroenterology & Hepatology
Giuseppe Vanella, Giuseppe Dell'Anna, Roy L. J. van Wanrooij, Michiel Bronswijk, Rogier P. Voermans, Wim Laleman, Hannah van Malenstein, Paul Fockens, Schalk van der Merwe, Paolo Giorgio Arcidiacono
Summary: Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) is an important treatment for distal malignant biliary obstruction. Recent studies have developed a classification and rescue strategies for stent dysfunction, with a reported need for reintervention during follow-up as high as 55%. This comprehensive analysis of nine cases provides insights into the pathophysiology, clinical reasoning, and technical considerations of dysfunction and rescue interventions, as well as practical tips and tricks.
DIGESTIVE ENDOSCOPY
(2023)
Article
Gastroenterology & Hepatology
Hae Won Yoo, Jong Ho Moon, Seok Jung Jo, Yun Nah Lee, Jae Keun Park, Tae Hoon Lee, Sang-Woo Cha, Young Deok Cho, Sang-Heum Park, Se Ik Park, Seok Jeong, Don Haeng Lee
Summary: The use of the novel electrocautery-enhanced LAMS for one-step EUS-guided gallbladder drainage or choledochoduodenostomy showed promising results with high success rates and safety in both animal and human studies.
Article
Gastroenterology & Hepatology
Benedetto Mangiavillano, Jong Ho Moon, Stefano Francesco Crino, Alberto Larghi, Khanh Do-Cong Pham, Anthony Yuen Bun Teoh, Danilo Paduano, Yun Nah Lee, Hae Won Yoo, Il Sang Shin, Gianenrico Rizzatti, Carlos Robles-Medranda, Roberto Oleas, Maria Cristina Conti Bellocchi, Francesco Aurienuna, Laura Lamonaca, Federica Spatola, Rita Conigliaro, Antonio Facciorusso, Armando Gabbrielli, Alessandro Repici
Summary: The study retrospectively evaluated the safety and success rates of a newly developed EC-LAMS, Hot-Spaxus, for various EUS-guided procedures.
Results showed high technical and clinical success rates of Hot-Spaxus for different interventional EUS indications.
The low rate of adverse events and similarity to outcomes of a control group treated with another EC-LAMS suggest that Hot-Spaxus is an effective and safe treatment option.
GASTROINTESTINAL ENDOSCOPY
(2022)