Article
Nutrition & Dietetics
Daniel Merenstein, Claire M. Fraser, Robert F. Roberts, Tian Liu, Silvia Grant-Beurmann, Tina P. Tan, Keisha Herbin Smith, Tom Cronin, Olivia A. Martin, Mary Ellen Sanders, Sean C. Lucan, Maureen A. Kane
Summary: Probiotic Bifidobacterium animalis subsp. lactis BB-12 demonstrates protection against antibiotic-induced disruptions in gut microbiota and short-chain fatty acids, enhancing microbial recovery. Compared to the control group, the BB-12 group showed smaller changes in fecal acetate levels and less loss in gut microbiota diversity after antibiotic treatment.
Article
Agriculture, Dairy & Animal Science
Magdalena Mazur-Kusnirek, Krzysztof Lipinski, Jens Noesgaard Jorgensen, Lea Hubertz Birch Hansen, Zofia Antoszkiewicz, Romuald Zabielski, Pawel Konieczka
Summary: This study assessed the impact of Bacillus-based probiotic diets on lactating sows and suckling piglets. The results showed that probiotic supplementation improved the reproductive performance of sows, enhanced the growth and health of piglets, and decreased feed costs.
Review
Biochemistry & Molecular Biology
Adrian Boicean, Victoria Birlutiu, Cristian Ichim, Paula Anderco, Sabrina Birsan
Summary: Inflammatory bowel diseases (IBD) are complex diseases characterized by chronic inflammation in the gastrointestinal tract. Fecal microbiota transplantation (FMT) has shown increasing effectiveness and safety in treating recurrent Clostridium difficile infection (CDI) and co-infection of SARS-CoV-2 and CDI. By modifying the gut microbiota, FMT offers an alternative approach to indirectly influence the host's immune system in a safe way, improving clinical symptoms and endoscopic findings in IBD patients. Further validation is needed to establish a clinical protocol for FMT in IBD.
Review
Cell Biology
Jayshree Mishra, Madyson Stubbs, Longxiang Kuang, Nitza Vara, Priyam Kumar, Narendra Kumar
Summary: Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract. Probiotics and their engineering show great potential in treating chronic inflammatory conditions, including IBD. Personalized probiotic treatment is important due to the diversity of the gut microbiome in different populations.
MEDIATORS OF INFLAMMATION
(2022)
Article
Immunology
Jie Wu, Liang Lv, Chunlian Wang
Summary: The meta-analysis examined the efficacy of fecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) and found inconsistent results. FMT administered via colonoscopy or gastroscope may benefit IBS patients and improve their quality of life. However, the quality of evidence supporting the use of FMT in IBS is very low.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Microbiology
Kirsten Grond, Artemis S. Louyakis, Sarah M. Hird
Summary: Many animals migrate long distances annually, and one important adaptation in shorebirds is their ability to rapidly gain weight at stopover locations. The role of the microbiome in weight gain in birds is still unclear, but there is evidence suggesting its involvement. In this study, we collected fecal samples from Ruddy Turnstones in Delaware Bay to investigate the microbiome composition and function during stopover weight gain. Our results show that both the taxonomic composition and function of the microbiome change during weight gain, and we identified genes associated with weight class and increased polyunsaturated fatty acid biosynthesis in the microbiota as birds gain weight. This study highlights the dynamic nature of the microbiome and its potential role in the rapid weight gain of shorebirds.
Article
Multidisciplinary Sciences
Jun Liu, Yixin Wang, William John Heelan, Yu Chen, Zhaoting Li, Quanyin Hu
Summary: Inflammatory bowel diseases (IBDs) are associated with elevated levels of reactive oxygen species (ROS) and dysregulated gut microbiota. In this study, researchers developed ROS-scavenging nanoparticles (HPN) to effectively scavenge ROS. They targeted the colon tissue by conjugating HPN to modified probiotic Escherichia coli Nissle 1917 (EcN). To enhance the efficacy of bacteriotherapy, the EcN cells were encapsulated with a poly-norepinephrine (NE) layer for protection against environmental assaults and prolonged retention in the intestine. The HPN-NE-EcN treatment showed enhanced efficacy in colitis models and increased abundance and diversity of gut microbiota.
Article
Chemistry, Multidisciplinary
Kairuo Wang, Qian Chen, Li Ding, Yefei Zhu, Xinyue Wang, Mengting Zhou, Meiqi Chang, Manman Pei, Yuanyuan Zhang, Yang Zhang, Yu Chen, Huanlong Qin
Summary: This study developed a mucoadhesive probiotic-mediated therapeutic strategy to achieve bioadhesion and prolong the residence time of oral medication in the intestinal tract. It effectively modulated intestinal inflammation and microbiota, enhancing the therapeutic effect.
Review
Biochemistry & Molecular Biology
Yuri Haneishi, Yuma Furuya, Mayu Hasegawa, Antonio Picarelli, Mauro Rossi, Junki Miyamoto
Summary: Inflammatory bowel disease (IBD) is a rapidly increasing inflammatory disease of the gastrointestinal tract worldwide. Recent research suggests that factors such as genetics, environment, microbiota, and immune responses are involved in its development, but the underlying causes are unclear. Dysbiosis of gut microbiota, particularly a decrease in specific genera, has been identified as a possible trigger for IBD. Improving gut microbiota and identifying specific bacterial species are crucial for understanding and treating IBD and autoimmune diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Microbiology
Marcio Vargas-Ramella, Mirian Pateiro, Aristide Maggiolino, Michele Faccia, Daniel Franco, Pasquale De Palo, Jose M. Lorenzo
Summary: Probiotics have been widely used in the food industry in the past two decades, with a growing focus on their health benefits for consumers. Strategies need to be developed to increase the consumption of functional foods to meet criteria for probiotic usefulness and the demands of the consumer market.
Letter
Gastroenterology & Hepatology
Yuka Ikeda, Kurumi Taniguchi, Haruka Sawamura, Ai Tsuji, Satoru Matsuda
Summary: Irritable bowel syndrome is an important health concern that may be linked to alterations in the microbiota of the gut-brain axis. Dietary intake can contribute to the production of D-amino acids, which play key roles in cellular physiological processes against oxidative stresses. The gut microbiota may have significant effects on emotional stability through the action of D-amino acids.
WORLD JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Microbiology
Jose F. Garcia-Mazcorro, Mercedes Amieva-Balmori, Arturo Triana-Romero, Bridgette Wilson, Leanne Smith, Job Reyes-Huerta, Megan Rossi, Kevin Whelan, Jose M. Remes-Troche
Summary: Increasing evidence suggests a microbial pathogenesis in irritable bowel syndrome (IBS), and this study found differences in the fecal microbiota between different IBS subtypes, and even within the same subtype depending on geographical location.
Article
Pharmacology & Pharmacy
Ning He, Gerong Shen, Xiaoqin Jin, Heyangzi Li, Jingyu Wang, Lintao Xu, Jun Chen, Xi Cao, Chunyan Fu, Dongling Shi, Xinghui Song, Shuangshuang Liu, Yanwei Li, Tengfei Zhao, Jun Li, Jinjie Zhong, Yueliang Shen, Mingzhi Zheng, Ying-ying Chen, Lin-lin Wang
Summary: Spinal cord injury can alter the gut microbiota and metabolites, affecting the prognosis of the injury. Resveratrol, with its anti-inflammatory properties, can restore the disrupted gut microbiota and increase the concentration of butyrate, promoting functional recovery after spinal cord injury.
PHARMACOLOGICAL RESEARCH
(2022)
Article
Microbiology
Oluwamayowa S. Akinsuyi, Luiz F. W. Roesch
Summary: The role of gut microbiota in osteoporosis has gained attention in recent years. A meta-analysis of five 16S rRNA data sets revealed significant compositional and functional microbial alterations associated with osteoporosis. Opportunistic pathogens were increased, while short-chain fatty acid producers were depleted in the osteoporosis group. Lactic acid-producing bacteria were significantly increased. Functional prediction showed differences in SCFA and amino acid biosynthesis pathways. This study provides insight into the pathogenesis of osteoporosis and potential therapeutic interventions.
MICROBIOLOGY SPECTRUM
(2023)
Article
Veterinary Sciences
Susan Ciaravolo, Lina Maria Martinez-Lopez, Richard J. N. Allcock, Andrew P. Woodward, Caroline Mansfield
Summary: This longitudinal microbiome study found that a commercially available veterinary synbiotic product did not significantly impact the microbial diversity of healthy dogs' fecal microbiome, but did result in transient increases in certain probiotic species, with the microbiota partially reverting to its baseline state after discontinuation of the product.
FRONTIERS IN VETERINARY SCIENCE
(2021)
