Article
Multidisciplinary Sciences
Tomohiko Yasuda, Hyun Seok Lee, Su Youn Nam, Hiroto Katoh, Yuko Ishibashi, Somay Yamagata Murayama, Hidenori Matsui, Hiroki Masuda, Emiko Rimbara, Nobuyuki Sakurazawa, Hideyuki Suzuki, Hiroshi Yoshida, Yasuyuki Seto, Shumpei Ishikawa, Seong Woo Jeon, Masahiko Nakamura, Sachiyo Nomura
Summary: Genetic analysis and culturing techniques for gastric non-Helicobacter pylori Helicobacter (NHPH) are advancing, with NHPH reported to accompany certain gastric conditions. A study on Korean gastric cancer patients found a low percentage positive for NHPH, suggesting it may play a role in gastric cancer development, albeit with lower pathogenicity compared to H. pylori.
SCIENTIFIC REPORTS
(2022)
Review
Cell Biology
Chia-Chen Ku, Kenly Wuputra, Jia-Bin Pan, Chia-Pei Li, Chung-Jung Liu, Yi-Chang Liu, Shigeo Saito, Te-Fu Chan, Chang-Shen Lin, Deng-Chyang Wu, Kazunari K. Yokoyama
Summary: There is significant cellular diversity in the human stomach, providing valuable insights into cell plasticity in normal development and tumorigenesis. This article focuses on cancer stem cells and their derived 3D organoids in culture, emphasizing the formation of stem cell niches. The role of H. p. infection and the specific markers of stomach-cancer-derived organoids induced by H. p. are also discussed.
Article
Gastroenterology & Hepatology
Chuan-Guo Guo, Ka Shing Cheung, Feifei Zhang, Esther W. Chan, Lijia Chen, Ian C. K. Wong, Wai K. Leung
Summary: This retrospective study in Hong Kong found that patients failed by initial H. pylori eradication have an increased risk of upper gastrointestinal bleeding compared to patients who responded to the initial therapy, and the risk increased progressively with longer time until retreatment. Therefore, early retreatment within 3 months should be considered to minimize subsequent risk of upper gastrointestinal bleeding.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2021)
Review
Gastroenterology & Hepatology
Amit Kumar Dutta, Perminder Singh Phull
Summary: Treatment options for H.pylori infection in patients with penicillin allergy include first-line Bismuth-based quadruple therapy for 10-14 days, and second-line Levoflaxacin-based triple therapy for 10 days. Patients with persistent infection after 2 treatment courses should be tested for penicillin allergy, and treatment should be guided by H.pylori culture and sensitivity testing results.
WORLD JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Multidisciplinary Sciences
Masaaki Kodama, Kazuhiro Mizukami, Yuka Hirashita, Tadayoshi Okimoto, Yasuhiro Wada, Masahide Fukuda, Sotaro Ozaka, Yoko Kudo, Kanako Ito, Ryo Ogawa, Kazuhisa Okamoto, Kensuke Fukuda, Kazunari Murakami
Summary: Although the prognosis of undifferentiated gastric cancer (UGC) diagnosed after Helicobacter pylori eradication (HPE) is poor, the characteristics of post-HPE UGC have not been well evaluated due to its low incidence. Female sex and absent follow-up were significant independent risk factors for post-HPE UGC.
Review
Pharmacology & Pharmacy
Renaly Ivyna de Araujo Rego, Geovana Ferreira Guedes Silvestre, Demis Ferreira de Melo, Sonaly Lima Albino, Marcela Monteiro Pimentel, Sara Brito Silva Costa Cruz, Sabrina Daniela Silva Wurzba, Wellington Francisco Rodrigues, Bolivar Ponciano Goulart de Lima Damasceno, Lucio Roberto Cancado Castellano
Summary: This article provides an overview of the biological and pharmacological activities of flavonoid-rich extracts, focusing on their use against Helicobacter pylori infection to prevent gastric cancer. The study finds that these extracts have potential anti-H. pylori activity, highlighting the importance of researching natural products.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yang Wu, Zhiyong Song, Guiyun Deng, Kai Jiang, Huajuan Wang, Xueji Zhang, Heyou Han
Summary: The study uses nanomotors loaded with drugs to combat gastric cancer caused by Helicobacter pylori infection, successfully achieving rapid neutralization of gastric acid and drug release in animal models to achieve good therapeutic effects.
Article
Nanoscience & Nanotechnology
Guiyun Deng, Yang Wu, Zhiyong Song, Shuojun Li, Moqing Du, Jiamin Deng, Quan Xu, Liu Deng, Hagar Shendy Bahlol, Heyou Han
Summary: Infection with Helicobacter pylori (Hp) is a major cause of stomach cancer. This study introduces nanoliposomes that can modify the gastric acid environment to effectively treat Hp infection. Results show that these nanoliposomes can eliminate Hp infection and reduce inflammation, suggesting a potential therapeutic strategy.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nutrition & Dietetics
Han-Na Kim, Min-Jeong Kim, Jonathan. P. P. Jacobs, Hyo-Joon Yang
Summary: This study investigated the microbial changes and host inflammatory cytokine responses in H. pylori-negative gastric cancer patients. The results showed that the gastric mucosal microbiota in GC patients had reduced diversity and a different composition compared to controls. Lacticaseibacillus was enriched, while Haemophilus and Campylobacter were depleted in the cancer group. Furthermore, the combined abundance of these taxa correlated significantly with gastric mucosal IL1B expression.
Review
Biochemistry & Molecular Biology
Rosanna Capparelli, Domenico Iannelli
Summary: Epigenetics plays a role in regulating gene expression, cell differentiation, and response to environmental stimuli. Helicobacter pylori (Hp) uses DNA methylation to silence genes in human gastric mucosa, which is a primary cause of gastric cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Pediatrics
Per Wandell, Axel C. Carlsson, Xinjun Li, Jan Sundquist, Kristina Sundquist
Summary: The risk of urolithiasis in second-generation immigrants was not significantly different from that of children with Swedish-born parents.
Article
Microbiology
Marcel Nkuize, Stephane De Wit, Pieter Demetter, Pierre Eisendrath, Jean Vanderpas
Summary: This study discusses the co-infection of Helicobacter pylori and human immunodeficiency virus (HIV) at the regional and sub-regional levels, with a focus on the incidence of gastric cancer.
Article
Gastroenterology & Hepatology
Sarah Wernly, Georg Semmler, Andreas Voelkerer, Maria Flamm, Elmar Aigner, David Niederseer, Bernhard Wernly, Christian Datz
Summary: This study examined the association between H. pylori positivity and cardiovascular (CV) risk and found that they were independently associated. However, there was no significant difference in CV mortality between H. pylori positive and H. pylori negative patients during a 9-year follow-up.
Article
Cardiac & Cardiovascular Systems
Per Wandell, Xinjun Li, Axel C. Carlsson, Jan Sundquist, Kristina Sundquist
Summary: The study found that foreign-born individuals generally have a lower risk of cardiomyopathies, but men from Africa and Asia have a higher risk of hypertrophic cardiomyopathies, and men from Nordic countries have a higher risk of dilated cardiomyopathies.
BMC CARDIOVASCULAR DISORDERS
(2022)
Article
Gastroenterology & Hepatology
Alanna Ebigbo, Joerg Marienhagen, Helmut Messmann
Summary: The regular arrangement of collecting venules (RAC) and the Kimura-Takemoto classification of atrophic change (KTC) are simple criteria that can reliably predict or rule out a Helicobacter pylori infection. These endoscopic features should be given attention by Western endoscopists and can be easily used to rule out such infections.
DIGESTIVE ENDOSCOPY
(2021)
Article
Oncology
Sandro Pasquali, Sylvie Bonvalot, Dimitri Tzanis, Paolo G. Casali, Annalisa Trama, Alessandro Gronchi
Article
Oncology
G. Gatta, A. Trama, R. Capocaccia
Article
Oncology
Panagis M. Lykoudis, Stefano Partelli, Francesca Muffatti, Martyn Caplin, Massimo Falconi, Giuseppe K. Fusai
Article
Obstetrics & Gynecology
Magdalena Bielska-Lasota, Silvia Rossi, Michalina Krzyzak, Annemie Haelens, Augius Domenic, Roberta De Angelis, Adam Maciejczyk, Miguel Rodriguez-Barranco, Vesna Zadnik, Pamela Minicozzi
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
(2020)
Correction
Oncology
Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt, Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt
Article
Oncology
Anita Feller, Katarina L. Matthes, Andrea Bordoni, Christine Bouchardy, Jean-Luc Bulliard, Christian Herrmann, Isabelle Konzelmann, Manuela Maspoli, Mohsen Mousavi, Sabine Rohrmann, Katharina Staehelin, Volker Arndt
Article
Oncology
Sabine Schmid, Jorune Suipyte, Christian Herrmann, Mohsen Mousavi, Felicitas Hitz, Martin Fruh
EUROPEAN JOURNAL OF CANCER CARE
(2020)
Article
Oncology
Salome Adam, Eva Martin-Diener, Bertrand Camey, Celine Egger Hayoz, Isabelle Konzelmann, Seyed Mohsen Mousavi, Christian Herrmann, Sabine Rohrmann, Miriam Wanner, Katharina Staehelin, Rato T. Strebel, Marco Randazzo, Hubert John, Hans-Peter Schmid, Volker Arndt
Article
Oncology
Christian Herrmann, Rudolf Morant, Esther Walser, Mohsen Mousavi, Beat Thurlimann
Summary: The study found that organized mammography screening programmes in Switzerland have a positive effect on lowering mastectomy rates. Participants in the screening program are significantly less likely to receive a mastectomy compared to non-participants, leading to a higher quality of life for many patients.
Article
Oncology
Charles A. Stiller, Laura Botta, Maria Jose Sanchez Perez, Maria Dolores Chirlaque Lopez, Rafael Marcos-Gragera, Tiziana Scuderi, Dyfed Wyn Huws, Annalisa Trama
Summary: This study provides updated information on the incidence and survival of Kaposi sarcoma in Europe from 1995 to 2007. The results show an increasing incidence rate with age, with males having a higher incidence than females. Portugal had the highest incidence of KS, and trends in incidence rates among European males aged 0-44 fluctuated significantly during the study period.
CANCER EPIDEMIOLOGY
(2021)
Article
Oncology
Fabio Girardi, Brian Rous, Charles A. Stiller, Gemma Gatta, Naomi Fersht, Hans H. Storm, Jessica R. Rodrigues, Christian Herrmann, Rafael Marcos-Gragera, Rafael Peris-Bonet, Mikhail Valkov, Hannah K. Weir, Ryan R. Woods, Hui You, Patricia A. Cueva, Prithwish De, Veronica Di Carlo, Tom Borge Johannesen, Carlos A. Lima, Charles F. Lynch, Michel P. Coleman, Claudia Allemani
Summary: This study is the first global account of the histology distribution of brain tumors in children and adults, based on data from the global CONCORD database for cancer survival trends. The findings provide insights into the practices and the quality of cancer registration worldwide.
Article
Oncology
Rafael Cardoso, Feng Guo, Thomas Heisser, Monika Hackl, Petra Ihle, Harlinde De Schutter, Nancy Van Damme, Zdravka Valerianova, Trajan Atanasov, Ondrej Majek, Jan Muzik, Mef Christina Nilbert, Anne Julie Tybjerg, Kaire Innos, Margit Magi, Nea Malila, Anne-Marie Bouvier, Veronique Bouvier, Guy Launoy, Anne-Sophie Woronoff, Melanie Cariou, Michel Robaszkiewicz, Patricia Delafosse, Florence Poncet, Alexander Katalinic, Paul M. Walsh, Carlo Senore, Stefano Rosso, Ieva Vincerzevskiene, Valery E. P. P. Lemmens, Marloes A. G. Elferink, Tom Borge Johannesen, Hartwig Korner, Frank Pfeffer, Maria Jose Bento, Jessica Rodrigues, Filipa Alves da Costa, Ana Miranda, Vesna Zadnik, Tina Zagar, Arantza Lopez de Munain Marques, Rafael Marcos-Gragera, Montse Puigdemont, Jaume Galceran, Maria Carulla, Maria-Dolores Chirlaque, Monica Ballesta, Kristina Sundquist, Jan Sundquist, Marco Weber, Andrea Jordan, Christian Herrmann, Mohsen Mousavi, Anton Ryzhov, Michael Hoffmeister, Hermann Brenner
Summary: There are diverse trends in colorectal cancer incidence, mortality, and stage distribution across European countries, mainly due to variations in the implementation of colorectal cancer screening programs.
Article
Environmental Sciences
Paolo Contiero, Giovanna Tagliabue, Gemma Gatta, Jaume Galceran, Jean-Luc Bulliard, Martina Bertoldi, Alessandra Scaburri, Emanuele Crocetti
Summary: Cancer incidence varies between and within countries, with localized geographic areas showing significant differences in incidence rates. Analysis of data from Latin Language Countries revealed areas with high cancer incidence, suggesting the presence of area-specific risk factors that require further investigation.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Pediatrics
Naomi Ssenyonga, Charles Stiller, Kayo Nakata, Jaime Shalkow, Sheilagh Redmond, Jean-Luc Bulliard, Fabio Girardi, Christine Fowler, Raphael Marcos-Gragera, Audrey Bonaventure, Nathalie Saint-Jacques, Pamela Minicozzi, Prithwish De, Miguel Rodriguez-Barranco, Siri Laronningen, Veronica Di Carlo, Margit Magi, Mikhail Valkov, Karri Seppa, Dyfed Wyn Huws, Michel P. Coleman, Claudia Allemani
Summary: The study examines global survival trends in leukemia among young patients aged 0-24 years, revealing significant variations in survival rates across different countries and regions. Children consistently have higher survival rates compared to adolescents and young adults.
LANCET CHILD & ADOLESCENT HEALTH
(2022)
Article
Medicine, General & Internal
Martin Andres, Anita Feller, Volker Arndt
Summary: There is no significant trend in age-adjusted incidence rates for chronic lymphocytic leukaemia (CLL)/small lymphocytic lymphoma (SLL) patients in Switzerland. However, age-standardised survival has improved over time, particularly in younger age groups, with statistically significant improvement seen in patients aged 65-74 years. Males have higher incidence rates, mortality rates, and shorter survival compared to females.
SWISS MEDICAL WEEKLY
(2021)
