期刊
FUTURE MICROBIOLOGY
卷 7, 期 9, 页码 1037-1046出版社
FUTURE MEDICINE LTD
DOI: 10.2217/FMB.12.82
关键词
antibiotic resistance; cosmonaut; gut; life support system; metagenome; microbiota; microgravity; space; spacecraft; virulence
类别
Space medicine research has drawn immense attention toward provision of efficient life support systems during long-term missions into space. However, in extended missions, a wide range of diseases may affect astronauts. In space medicine research, the gastrointestinal microbiome and its role in maintaining astronauts' health has received little attention. We would like to draw researchers' attention to the significant role of microblota. Because of the high number of microorganisms in the human body, man has been called a 'supra-organism' and gastrointestinal flora has been referred to as 'a virtual organ of the human body'. In space, the lifestyle, sterility of spaceship and environmental stresses can result in alterations in intestinal microbiota, which can lead to an impaired immunity and predispose astronauts to illness. This concern is heightened by increase in virulence of pathogens in microgravity. Thus, design of a personal probiotic kit is recommended to improve the health status of astronauts.
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