Innate immune evasion strategies of influenza viruses

Protective role of interferon-induced Mx GTPases against influenza viruses

(2016) O. HALLER et al.   REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES

Cutting Edge: Innate Immune Response Triggered by Influenza A Virus Is Negatively Regulated by SOCS1 and SOCS3 through a RIG-I/IFNAR1-Dependent Pathway

(2014) J. Pothlichet et al.   JOURNAL OF IMMUNOLOGY

Antiviral-Activated Dendritic Cells: A Paracrine-Induced Response State

(2014) A. V. Borderia et al.   JOURNAL OF IMMUNOLOGY

A Signaling Polypeptide Derived from an Innate Immune Adaptor Molecule Can Be Harnessed as a New Class of Vaccine Adjuvant

(2014) K. Kobiyama et al.   JOURNAL OF IMMUNOLOGY

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections

(2009) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Autophagy is involved in influenza A virus replication

(2009) Zhi Zhou et al.   Autophagy

Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes

(2009) Monique Gannagé et al.   Cell Host & Microbe

Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

(2009) Michaela Ulrike Gack et al.   Cell Host & Microbe

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Structural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymerase

(2009) Kanako Sugiyama et al.   EMBO JOURNAL

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy

(2009) S. Ludwig   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic cells require a systemic type I interferon response to mature and induce CD4+Th1 immunity with poly IC as adjuvant

(2009) M. Paula Longhi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differential regulation of antiviral and proinflammatory cytokines and suppression of Fas-mediated apoptosis by NS1 of H9N2 avian influenza virus in chicken macrophages

(2009) Z. Xing et al.   JOURNAL OF GENERAL VIROLOGY

Cutting Edge: Stealth Influenza Virus Replication Precedes the Initiation of Adaptive Immunity

(2009) B. Moltedo et al.   JOURNAL OF IMMUNOLOGY

Innate immune control and regulation of influenza virus infections

(2009) Jodi McGill et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intranasal Administration of Alpha Interferon Reduces Seasonal Influenza A Virus Morbidity in Ferrets

(2009) D. Kugel et al.   JOURNAL OF VIROLOGY

Experimental Infection of Pigs with the Human 1918 Pandemic Influenza Virus

(2009) H. M. Weingartl et al.   JOURNAL OF VIROLOGY

Pathogenesis of 1918 Pandemic and H5N1 Influenza Virus Infections in a Guinea Pig Model: Antiviral Potential of Exogenous Alpha Interferon To Reduce Virus Shedding

(2009) N. Van Hoeven et al.   JOURNAL OF VIROLOGY

Adaptive Mutations Resulting in Enhanced Polymerase Activity Contribute to High Virulence of Influenza A Virus in Mice

(2009) T. Rolling et al.   JOURNAL OF VIROLOGY

The NS1 Protein of the 1918 Pandemic Influenza Virus Blocks Host Interferon and Lipid Metabolism Pathways

(2009) R. Billharz et al.   JOURNAL OF VIROLOGY

The NS1 Protein of a Human Influenza Virus Inhibits Type I Interferon Production and the Induction of Antiviral Responses in Primary Human Dendritic and Respiratory Epithelial Cells

(2009) K. Haye et al.   JOURNAL OF VIROLOGY

Early Control of H5N1 Influenza Virus Replication by the Type I Interferon Response in Mice

(2009) K. J. Szretter et al.   JOURNAL OF VIROLOGY

Differential Regulation of Human Interferon A Gene Expression by Interferon Regulatory Factors 3 and 7

(2009) P. Genin et al.   MOLECULAR AND CELLULAR BIOLOGY

Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

(2009) Gavin J. D. Smith et al.   NATURE

Emergence and pandemic potential of swine-origin H1N1 influenza virus

(2009) Gabriele Neumann et al.   NATURE

Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site

(2009) Puwei Yuan et al.   NATURE

The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit

(2009) Alexandre Dias et al.   NATURE

Preclinical Evaluation of a Replication-Deficient Intranasal ΔNS1 H5N1 Influenza Vaccine

(2009) Julia Romanova et al.   PLoS One

Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

(2009) C. R. Baskin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging antiviral targets for influenza A virus

(2009) Robert M. Krug et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A TLR3 ligand that exhibits potent inhibition of influenza virus replication and has strong adjuvant activity has the potential for dual applications in an influenza pandemic

(2009) Yuk-Fai Lau et al.   VACCINE

Development of a live-attenuated influenza B ΔNS1 intranasal vaccine candidate

(2009) Nina Wressnigg et al.   VACCINE

Influenza B Virus Ribonucleoprotein Is a Potent Activator of the Antiviral Kinase PKR

(2009) Bianca Dauber et al.   PLoS Pathogens

Structure of NS1A effector domain from the influenza A/Udorn/72 virus

(2008) Shuangluo Xia et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

(2008) H HOFFMANN et al.   ANTIVIRAL RESEARCH

Adjuvant activity of type I interferons

(2008) Michael G. Tovey et al.   BIOLOGICAL CHEMISTRY

Clinical uses of interferons

(2008) Robert M. Friedman   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Structural basis for dsRNA recognition by NS1 protein of influenza A virus

(2008) Ao Cheng et al.   CELL RESEARCH

Influenza A viruses with truncated NS1 as modified live virus vaccines: Pilot studies of safety and efficacy in horses

(2008) T. M. Chambers et al.   EQUINE VETERINARY JOURNAL

Influenza A virus abrogates IFN-γ response in respiratory epithelial cells by disruption of the Jak/Stat pathway

(2008) Kohsaku Uetani et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Structural Mechanism of RNA Recognition by the RIG-I-like Receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNITY

Regulation of Mitochondrial Antiviral Signaling Pathways

(2008) Chris B. Moore et al.   IMMUNITY

RNA recognition and signal transduction by RIG-I-like receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNOLOGICAL REVIEWS

Different Roles for Two Ubiquitin-like Domains of ISG15 in Protein Modification

(2008) Yong-Gang Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The multifunctional NS1 protein of influenza A viruses

(2008) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Mice Lacking the ISG15 E1 Enzyme UbE1L Demonstrate Increased Susceptibility to both Mouse-Adapted and Non-Mouse-Adapted Influenza B Virus Infection

(2008) C. Lai et al.   JOURNAL OF VIROLOGY

Influenza A Virus Strains Differ in Sensitivity to the Antiviral Action of Mx-GTPase

(2008) J. Dittmann et al.   JOURNAL OF VIROLOGY

Influenza B Virus NS1-Truncated Mutants: Live-Attenuated Vaccine Approach

(2008) R. Hai et al.   JOURNAL OF VIROLOGY

Live Attenuated Influenza Viruses Containing NS1 Truncations as Vaccine Candidates against H5N1 Highly Pathogenic Avian Influenza

(2008) J. Steel et al.   JOURNAL OF VIROLOGY

Novel Influenza Virus NS1 Antagonists Block Replication and Restore Innate Immune Function

(2008) D. Basu et al.   JOURNAL OF VIROLOGY

Influenza A Virus Polymerase Is an Integral Component of the CPSF30-NS1A Protein Complex in Infected Cells

(2008) R.-L. Kuo et al.   JOURNAL OF VIROLOGY

X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus

(2008) Zachary A. Bornholdt et al.   NATURE

Drosophila RNAi screen identifies host genes important for influenza virus replication

(2008) Linhui Hao et al.   NATURE

The structural basis for cap binding by influenza virus polymerase subunit PB2

(2008) Delphine Guilligay et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Influenza A H5N1 Clade 2.3.4 Virus with a Different Antiviral Susceptibility Profile Replaced Clade 1 Virus in Humans in Northern Vietnam

(2008) Mai T. Q. Le et al.   PLoS One

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

(2008) R. J. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for suppression of a host antiviral response by influenza A virus

(2008) K. Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

(2008) M. U. Gack et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of an avian influenza A virus NS1 protein effector domain

(2008) Benjamin G. Hale et al.   VIROLOGY

Domestic Pigs Have Low Susceptibility to H5N1 Highly Pathogenic Avian Influenza Viruses

(2008) Aleksandr S. Lipatov et al.   PLoS Pathogens

Influenza A Virus Inhibits Type I IFN Signaling via NF-κB-Dependent Induction of SOCS-3 Expression

(2008) Eva-K. Pauli et al.   PLoS Pathogens

Interferon-λ Contributes to Innate Immunity of Mice against Influenza A Virus but Not against Hepatotropic Viruses

(2008) Markus Mordstein et al.   PLoS Pathogens

Interferon-β Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances Their Activation by Influenza Virus

(2008) Hannah Phipps-Yonas et al.   PLoS Pathogens

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY