Molecular and physiologic basis of quinoline drug resistance inPlasmodium falciparummalaria

Role of Known Molecular Markers of Resistance in the Antimalarial Potency of Piperaquine and Dihydroartemisinin In Vitro

(2009) S. Muangnoicharoen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

P. falciparum Na+/H+ exchanger (PfNHE) function and quinine resistance (QNR)

(2009) Paul D. Roepe et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Probing the multifactorial basis of Plasmodium falciparum quinine resistance: Evidence for a strain-specific contribution of the sodium-proton exchanger PfNHE

(2009) Louis J. Nkrumah et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Photoaffinity Labeling of thePlasmodium falciparumChloroquine Resistance Transporter with a Novel Perfluorophenylazido Chloroquine†

(2008) Jacqueline K. Lekostaj et al.   BIOCHEMISTRY

Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas

(2008) Kekeli Ekoue-Kovi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Quinine and Chloroquine Differentially Perturb Heme Monomer−Dimer Equilibrium

(2008) Leah B. Casabianca et al.   INORGANIC CHEMISTRY

Characteristics ofPlasmodium falciparum dhfrHaplotypes That Confer Pyrimethamine Resistance, Kilifi, Kenya, 1987–2006

(2008) Laura K. Certain et al.   JOURNAL OF INFECTIOUS DISEASES

4-N-, 4-S-, and 4-O-Chloroquine Analogues: Influence of Side Chain Length and Quinolyl Nitrogen pKaon Activity vs Chloroquine Resistant Malaria

(2008) Jayakumar K. Natarajan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Overcoming Drug Resistance to Heme-Targeted Antimalarials by Systematic Side Chain Variation of 7-Chloro-4-aminoquinolines

(2008) Kimberly Yearick et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials

(2008) Charles B. Davis et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Acid extrusion from the intraerythrocytic malaria parasite is not via a Na+/H+ exchanger

(2008) Natalie J. Spillman et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy

(2008) Bojana Gligorijevic et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Four distinct pathways of hemoglobin uptake in the malaria parasite Plasmodium falciparum

(2008) D. A. Elliott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo

(2007) Livia Vivas et al.   ACTA TROPICA

A single S1034C mutation confers altered drug sensitivity to PfMDR1 ATPase activity that is characteristic of the 7G8 isoform

(2007) Jacqueline K. Lekostaj et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY