The role of disulfide bonds in structure and activity of chlorotoxin

Semienzymatic Cyclization of Disulfide-rich Peptides Using Sortase A

(2014) Xinying Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Grafting onto a Stable Framework Yields Novel Cyclic Peptides for the Treatment of Multiple Sclerosis

(2013) Conan K. Wang et al.   ACS Chemical Biology

Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors

(2013) Joy L. Kovar et al.   ANALYTICAL BIOCHEMISTRY

Recombinant expression of backbone-cyclized polypeptides

(2013) Radhika Borra et al.   BIOPOLYMERS

Cyclization of the Antimicrobial Peptide Gomesin with Native Chemical Ligation: Influences on Stability and Bioactivity

(2013) Lai Yue Chan et al.   CHEMBIOCHEM

Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics

(2013) Miriam Góngora-Benítez et al.   CHEMICAL REVIEWS

The Cyclic Cystine Ladder in θ-Defensins Is Important for Structure and Stability, but Not Antibacterial Activity

(2013) Anne C. Conibear et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide

(2013) Yanbin Ji et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment

(2013) Pedro M Costa et al.   Molecular Therapy-Nucleic Acids

Orally Active Peptidic Bradykinin B1 Receptor Antagonists Engineered from a Cyclotide Scaffold for Inflammatory Pain Treatment

(2012) Clarence T. T. Wong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Bio-imaging Using Chlorotoxin-based Conjugates

(2012) Mark R. Stroud et al.   CURRENT PHARMACEUTICAL DESIGN

Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells

(2012) Nora Graf et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Biological Activities of Natural and Engineered Cyclotides, a Novel Molecular Scaffold for Peptide-Based Therapeutics

(2012) Angie E. Garcia et al.   Current Molecular Pharmacology

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

(2011) L. Y. Chan et al.   BLOOD

Bioactive cystine knot proteins

(2011) Norelle L Daly et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Chemical Re-engineering of Chlorotoxin Improves Bioconjugation Properties for Tumor Imaging and Targeted Therapy

(2011) Muharrem Akcan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Effects of Cyclization on Stability, Structure, and Activity of α-Conotoxin RgIA at the α9α10 Nicotinic Acetylcholine Receptor and GABABReceptor

(2011) Reena Halai et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

(2010) Richard J. Clark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stabilization of α-Conotoxin AuIB: Influences of Disulfide Connectivity and Backbone Cyclization

(2010) Erica S. Lovelace et al.   ANTIOXIDANTS & REDOX SIGNALING

Interlocking Disulfides in Circular Proteins: Toward Efficient Oxidative Folding of Cyclotides

(2010) Teshome Leta Aboye et al.   ANTIOXIDANTS & REDOX SIGNALING

A new “era” for cyclotide sequencing

(2010) Michelle L. Colgrave et al.   BIOPOLYMERS

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

(2009) Conan K. Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

(2009) Kamala Kesavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY