标题
Targeting cancer cell mitochondria as a therapeutic approach
作者
关键词
-
出版物
Future Medicinal Chemistry
Volume 5, Issue 1, Pages 53-67
出版商
Future Science, LTD
发表日期
2012-12-21
DOI
10.4155/fmc.12.190
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A New 4-phenyl-1,8-naphthyridine Derivative Affects Carcinoma Cell Proliferation by Impairing Cell Cycle Progression and Inducing Apoptosis
- (2012) Antonella Capozzi et al. Anti-Cancer Agents in Medicinal Chemistry
- Pyruvate fuels mitochondrial respiration and proliferation of breast cancer cells: effect of monocarboxylate transporter inhibition
- (2012) Anne R. Diers et al. BIOCHEMICAL JOURNAL
- Anticancer Activity of Silver-N-Heterocyclic Carbene Complexes: Caspase-Independent Induction of Apoptosis via Mitochondrial Apoptosis-Inducing Factor (AIF)
- (2012) Laure Eloy et al. ChemMedChem
- Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Propyl Ester
- (2012) Zhenjie Tang et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Berberine Induces Caspase-Independent Cell Death in Colon Tumor Cells through Activation of Apoptosis-Inducing Factor
- (2012) Lihong Wang et al. PLoS One
- Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy
- (2012) Weiqin Lu et al. PLOS BIOLOGY
- Mitochondria as Therapeutic Targets for the Treatment of Malignant Disease
- (2011) Simone Fulda et al. ANTIOXIDANTS & REDOX SIGNALING
- Inhibition of Mitochondrial Respiration and Rapid Depletion of Mitochondrial Glutathione by β-Phenethyl Isothiocyanate: Mechanisms for Anti-Leukemia Activity
- (2011) Gang Chen et al. ANTIOXIDANTS & REDOX SIGNALING
- Combined effect of sodium selenite and docetaxel on PC3 metastatic prostate cancer cell line
- (2011) Mariana Freitas et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death
- (2011) Andrey V. Kuznetsov et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells
- (2011) Guozhu Chen et al. BMC CANCER
- Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease
- (2011) B H Kang et al. BRITISH JOURNAL OF CANCER
- The anti-tumour compound, RH1, causes mitochondria-mediated apoptosis by activating c-Jun N-terminal kinase
- (2011) Moon-Taek Park et al. BRITISH JOURNAL OF PHARMACOLOGY
- A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death
- (2011) Michael R. Freeman et al. CANCER BIOLOGY & THERAPY
- Chemo-resistant melanoma sensitized by tamoxifen to low dose curcumin treatment through induction of apoptosis and autophagy
- (2011) Sudipa June Chatterjee et al. CANCER BIOLOGY & THERAPY
- Inhibition of Mitochondrial Translation as a Therapeutic Strategy for Human Acute Myeloid Leukemia
- (2011) Marko Škrtić et al. CANCER CELL
- Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF- B/IL-8 Pathway that Drives Tumor Angiogenesis
- (2011) F. Vegran et al. CANCER RESEARCH
- The mitochondrial protein C1qbp promotes cell proliferation, migration and resistance to cell death
- (2011) Allison M. McGee et al. CELL CYCLE
- Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis
- (2011) Raghu Gogada et al. CELL CYCLE
- The Adenine Nucleotide Translocase 2, a Mitochondrial Target for Anticancer Biotherapy
- (2011) Ossama Sharaf el dein et al. CURRENT DRUG TARGETS
- New insights of mitochondria reactive oxygen species generation and cell apoptosis induced by low dose photodynamic therapy
- (2011) Hongyou Zhao et al. EUROPEAN JOURNAL OF CANCER
- Synthesis, characterization, antiproliferative and anti-metastatic properties of two ruthenium–DMSO complexes containing 2,2′-biimidazole
- (2011) Caiping Tan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Acetylsalicylic acid-induced oxidative stress, cell cycle arrest, apoptosis and mitochondrial dysfunction in human hepatoma HepG2 cells
- (2011) Haider Raza et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes
- (2011) Xu Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy
- (2011) Lan-Feng Dong et al. FREE RADICAL BIOLOGY AND MEDICINE
- Targeting Energy Metabolic and Oncogenic Signaling Pathways in Triple-negative Breast Cancer by a Novel Adenosine Monophosphate-activated Protein Kinase (AMPK) Activator
- (2011) Kuen-Haur Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Resveratrol Induces p53-independent, X-linked Inhibitor of Apoptosis Protein (XIAP)-mediated Bax Protein Oligomerization on Mitochondria to Initiate CytochromecRelease and Caspase Activation
- (2011) Raghu Gogada et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemical Genetics Analysis of an Aniline Mustard Anticancer Agent Reveals Complex I of the Electron Transport Chain as a Target
- (2011) Bogdan I. Fedeles et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells
- (2011) J. G. Valero et al. JOURNAL OF CELL SCIENCE
- The novel phloroglucinol PMT7 kills glycolytic cancer cells by blocking autophagy and sensitizing to nutrient stress
- (2011) Kate Broadley et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Surface modification of liposomes with rhodamine-123-conjugated polymer results in enhanced mitochondrial targeting
- (2011) Swati Biswas et al. JOURNAL OF DRUG TARGETING
- Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
- (2011) Zuzana Zachar et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mitochondria Determine the Efficacy of Anticancer Agents that Interact with DNA but Not the Cytoskeleton
- (2011) K. Hara et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells
- (2011) Ramon C Sun et al. Molecular Cancer
- Pancratistatin Selectively Targets Cancer Cell Mitochondria and Reduces Growth of Human Colon Tumor Xenografts
- (2011) C. Griffin et al. MOLECULAR CANCER THERAPEUTICS
- Differential Expression of the 18 kDa Translocator Protein (TSPO) by Neoplastic and Inflammatory Cells in Mouse Tumors of Breast Cancer
- (2011) Jinzi Zheng et al. MOLECULAR PHARMACEUTICS
- Mitochondrial Pathway Mediates the Antileukemic Effects of Hemidesmus Indicus, a Promising Botanical Drug
- (2011) Carmela Fimognari et al. PLoS One
- Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
- (2011) T. N. Chonghaile et al. SCIENCE
- Involvement of lipid rafts in the localization and dysfunction effect of the antitumor ether phospholipid edelfosine in mitochondria
- (2011) F Mollinedo et al. Cell Death & Disease
- Metabolic alterations in cancer cells and therapeutic implications
- (2011) Naima Hammoudi et al. Chinese Journal of Cancer
- Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis
- (2010) Nyree Crawford et al. APOPTOSIS
- Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells
- (2010) Fei Wang et al. APOPTOSIS
- Identification and biological activities of a new antiangiogenic small molecule that suppresses mitochondrial reactive oxygen species
- (2010) Ki Hyun Kim et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death
- (2010) Allison M. McGee et al. BIOCHEMICAL JOURNAL
- Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism
- (2010) Arnaud Chevrollier et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Degradation of HER2/neu by ANT2 shRNA suppresses migration and invasiveness of breast cancer cells
- (2010) Ji-Young Jang et al. BMC CANCER
- Mitochondrial p32/C1QBP is highly expressed in prostate cancer and is associated with shorter prostate-specific antigen relapse time after radical prostatectomy
- (2010) Rie Amamoto et al. CANCER SCIENCE
- ARF in the mitochondria: The last frontier?
- (2010) Koji Itahana et al. CELL CYCLE
- Sonodynamic and photodynamic mechanisms of action of the novel hypocrellin sonosensitizer, SL017: mitochondrial cell death is attenuated by 11, 12-epoxyeicosatrienoic acid
- (2010) Haitham E. El-Sikhry et al. INVESTIGATIONAL NEW DRUGS
- Amphipathic Tail-anchoring Peptide and Bcl-2 Homology Domain-3 (BH3) Peptides from Bcl-2 Family Proteins Induce Apoptosis through Different Mechanisms
- (2010) Jae-Kyun Ko et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II
- (2010) Lan-Feng Dong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds
- (2010) Gang Chen et al. MITOCHONDRION
- Mitochondrial p32 Protein Is a Critical Regulator of Tumor Metabolism via Maintenance of Oxidative Phosphorylation
- (2010) V. Fogal et al. MOLECULAR AND CELLULAR BIOLOGY
- Short-hairpin RNA-induced suppression of adenine nucleotide translocase-2 in breast cancer cells restores their susceptibility to TRAIL-induced apoptosis by activating JNK and modulating TRAIL receptor expression
- (2010) Ji-Young Jang et al. Molecular Cancer
- HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way
- (2010) Bin Peng et al. Molecular Cancer
- Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders
- (2010) Rainer Rupprecht et al. NATURE REVIEWS DRUG DISCOVERY
- Natural Proteasome Inhibitor Celastrol Suppresses Androgen-Independent Prostate Cancer Progression by Modulating Apoptotic Proteins and NF-kappaB
- (2010) Yao Dai et al. PLoS One
- Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate
- (2009) Zhao Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Small mitochondria-targeting molecules as anti-cancer agents
- (2009) Feng Wang et al. MOLECULAR ASPECTS OF MEDICINE
- Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
- (2009) Dunyaporn Trachootham et al. NATURE REVIEWS DRUG DISCOVERY
- Development of mitochondria-targeted derivatives of resveratrol
- (2008) Lucia Biasutto et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism
- (2008) D. Trachootham et al. BLOOD
- Mitochondrial p32 Is a Critical Mediator of ARF-Induced Apoptosis
- (2008) Koji Itahana et al. CANCER CELL
- VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis
- (2008) Leo Veenman et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II
- (2008) L-F Dong et al. ONCOGENE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started