Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer’s disease

Cdc25B Phosphatase Inhibitors in Cancer Therapy: Latest Developments, Trends and Medicinal Chemistry Perspective

(2012) Antonio Lavecchia et al.   Anti-Cancer Agents in Medicinal Chemistry

Enhanced Phosphatase Activity Attenuates  -Synucleinopathy in a Mouse Model

(2011) K.-W. Lee et al.   JOURNAL OF NEUROSCIENCE

Open-label, phase I dose-escalation study of sodium selenate, a novel activator of PP2A, in patients with castration-resistant prostate cancer

(2010) N M Corcoran et al.   BRITISH JOURNAL OF CANCER

Vitamin E Forms in Alzheimer's Disease: A Review of Controversial and Clinical Experiences

(2010) Owoedimo B. Usoro et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment

(2010) Xiaochuan Wang et al.   FASEB JOURNAL

Sphingosine Interaction with Acidic Leucine-rich Nuclear Phosphoprotein-32A (ANP32A) Regulates PP2A Activity and Cyclooxygenase (COX)-2 Expression in Human Endothelial Cells

(2010) Cheryl Habrukowich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of Tau at Thr212, Thr231, and Ser262Combined Causes Neurodegeneration

(2010) Alejandra D. Alonso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of Brain-Penetrant, Orally Bioavailable Aminothienopyridazine Inhibitors of Tau Aggregation

(2010) Carlo Ballatore et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Inhibitory Activity of Cholinesterases, and Neuroprotective Profile of Novel 1,8-Naphthyridine Derivatives

(2010) Cristóbal de los Ríos et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease

(2010) Steven P. Braithwaite et al.   NEUROBIOLOGY OF DISEASE

Sodium selenate mitigates tau pathology, neurodegeneration, and functional deficits in Alzheimer's disease models

(2010) J. van Eersel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of Tau Aggregation Inhibitors for Alzheimer's Disease

(2009) Bruno Bulic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nutritional status of selenium in Alzheimer's disease patients

(2009) Bárbara Rita Cardoso et al.   BRITISH JOURNAL OF NUTRITION

Taurolidine and oxidative stress: a rationale for local treatment of mesothelioma

(2009) N. Aceto et al.   EUROPEAN RESPIRATORY JOURNAL

Progesterone decreases tyrosine hydroxylase phosphorylation state and increases protein phosphatase 2A activity in the stalk-median eminence on proestrous afternoon

(2009) Bin Liu et al.   JOURNAL OF ENDOCRINOLOGY

Structure−Activity Relationship of Cyanine Tau Aggregation Inhibitors

(2009) Edward Chang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Activation of p38 Mitogen-Activated Protein Kinase Is Required for Death Receptor-Independent Caspase-8 Activation and Cell Death in Response to Sphingosine

(2009) C.-H. Yoon et al.   MOLECULAR CANCER RESEARCH

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease

(2009) Alessio Colombo et al.   NEUROBIOLOGY OF DISEASE

Dithiolethione compounds inhibit Akt signaling in human breast and lung cancer cells by increasing PP2A activity

(2009) C H Switzer et al.   ONCOGENE

Protein phosphatase 2A (PP2A), a drugable tumor suppressor in Ph1(+) leukemias

(2008) Danilo Perrotti et al.   CANCER AND METASTASIS REVIEWS

Structural Mechanism of Demethylation and Inactivation of Protein Phosphatase 2A

(2008) Yongna Xing et al.   CELL

Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling

(2008) Archana Mukhopadhyay et al.   FASEB JOURNAL

Tau hyperphosphorylation correlates with reduced methylation of protein phosphatase 2A

(2008) Xin-Wen Zhou et al.   NEUROBIOLOGY OF DISEASE

Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis

(2008) Scott A. Small et al.   NEURON

Tau-based treatment strategies in neurodegenerative diseases

(2008) Anja Schneider et al.   Neurotherapeutics