New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB

Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents

(2010) B. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

(2009) Katherine A. Rawls et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Salmonella Effector SptP Dephosphorylates Host AAA+ ATPase VCP to Promote Development of its Intracellular Replicative Niche

(2009) Daniel Humphreys et al.   Cell Host & Microbe

Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages

(2009) Nicola J. Beresford et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly

(2009) Gregor Hagelueken et al.   JOURNAL OF MOLECULAR BIOLOGY

Pathogen trafficking pathways and host phosphoinositide metabolism

(2009) Stefan S. Weber et al.   MOLECULAR MICROBIOLOGY

High-Throughput Discovery ofMycobacterium tuberculosisProtein Tyrosine Phosphatase B (MptpB) Inhibitors Using Click Chemistry

(2009) Lay Pheng Tan et al.   ORGANIC LETTERS

Discovery of a New Class of Inhibitors ofMycobacterium tuberculosisProtein Tyrosine Phosphatase B by Biology-Oriented Synthesis

(2008) Andrea Nören-Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic chalcones as efficient inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase PtpA

(2008) Louise Domeneghini Chiaradia et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mycobacterium tuberculosis Virulence Is Mediated by PtpA Dephosphorylation of Human Vacuolar Protein Sorting 33B

(2008) Horacio Bach et al.   Cell Host & Microbe

Protein tyrosine phosphatase PtpA is not required forMycobacterium tuberculosisgrowth in mice

(2008) Christoph Grundner et al.   FEMS MICROBIOLOGY LETTERS

Mycobacterial Ser/Thr protein kinases and phosphatases: Physiological roles and therapeutic potential

(2007) Annemarie Wehenkel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The biology and future prospects of antivirulence therapies

(2007) Lynette Cegelski et al.   NATURE REVIEWS MICROBIOLOGY