Article
Nutrition & Dietetics
Adrianne K. Griebel-Thompson, Scott Sands, Lynn Chollet-Hinton, Danielle Christifano, Debra K. Sullivan, Holly Hull, Juliana Teruel Camargo, Susan E. Carlson
Summary: This study investigated iodine intake and iodine status in a large cohort of US pregnant women. The results showed that iodine intake from diet was inadequate and nearly half of the women did not meet the recommended intake even with supplementation. About half of the women also had insufficient urinary iodine concentration. Therefore, there is a high prevalence of iodine insufficiency among pregnant women in the US.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Nutrition & Dietetics
Carla A. Lopes, Marta Duarte, Susana Prazeres, Ivone Carvalho, Laura Vilarinho, Jose Martinez-de-Oliveira, Edward Limbert, Manuel C. Lemos
Summary: This study investigated the impact of maternal iodine intake during pregnancy on the growth and neurodevelopment of children. The results showed that there was no direct effect of maternal iodine intake on child development, and socioeconomic factors may play a significant role in both maternal iodine intake and child outcomes.
Article
Nutrition & Dietetics
Li Huang, Li Zhang, Zhiyong Rao, Chengyu Huang, Hui Huang
Summary: This study aimed to characterize the iodine nutritional status of healthy pregnant women in Chengdu by measuring urinary iodine and analyzing dietary iodine intake. Results showed that the dietary iodine sources of the pregnant women were mainly seafood, iodized salt, iodized multivitamins, and daily food, indicating an appropriate iodine nutritional status in this population. There is a strong correlation between dietary iodine intake and UI concentration, with the 7-day dietary record being a useful method for evaluating dietary iodine status.
ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Aniceta A. Mikulska, Dorota Filipowicz, Franciszek K. Glowka, Ewelina Szczepanek-Parulska, Marek Ruchala, Michal Bartecki, Marta Karazniewicz-Lada
Summary: A novel ion-pair HPLC-UV method was developed for measuring iodine concentration in clinical samples, showing sufficient precision and accuracy. The study revealed that urinary iodine concentration in pregnant women was influenced by iodine supplementation, with the non-supplemented group having lower levels compared to the supplemented group.
Article
Nutrition & Dietetics
Kjersti Sletten Bakken, Tonje Eiane Aarsland, Synne Groufh-Jacobsen, Beate Stokke Solvik, Elfin Lovise Folven Gjengedal, Sigrun Henjum, Tor Arne Strand
Summary: This study evaluated iodine status in Norwegian infants and found that infants in the inland area of Norway had adequate iodine levels. Weaned infants had higher iodine intake and urinary iodine concentration compared to exclusively breastfed and partially breastfed infants, indicating that dietary data may not accurately capture iodine intake in infants.
Review
Endocrinology & Metabolism
Xueqi Zhang, Fan Zhang, Qiuxian Li, Renaguli Aihaiti, Chuyao Feng, Deshi Chen, Xu Zhao, Weiping Teng
Summary: The effect of iodine on papillary thyroid cancer has been controversial. This study analyzed the relationship between urinary iodine concentration and PTC using case-control studies. The results showed that excessive iodine intake was positively associated with PTC occurrence, while adequate iodine intake may be a protective factor. However, there was no significant association between urinary iodine and BRAF mutation or lymph node metastasis in PTC patients. The measurement method of urinary iodine may influence the study results.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ye Bu, Lin Yuan, Chunyuan Tian, Chunyan Zhao, Chunlei Ji, Xiaoxu Gao, Yan Cai, Dianjun Sun, Ying Liu
Summary: The study established reference intervals and impact factors for urinary creatinine and urinary iodine during pregnancy. Pregnancy weight was found to influence urinary creatinine excretion, while the estimated 24-hour urinary iodine excretion showed good consistency with the actual value.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2021)
Article
Endocrinology & Metabolism
Yiming Wu, Jie Yang, Qing Su, Hongxia Gu, Li Qin
Summary: This study aimed to assess the iodine status and its associations with thyroid function in pregnant women of Shanghai. A total of 562 pregnant women were included and their serum thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thyroid peroxidase antibody (TPOAB), thyroglobulin antibody (TGAB), and urinary iodine concentration (UIC) were measured. The results showed that the median UIC of the pregnant women studied was 158.25 & mu;g/L. Both low and high gestational iodine status were related to thyroid function and autoimmunity, highlighting the importance of optimal iodine nutrition during pregnancy.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Multidisciplinary Sciences
Rola Al Ghali, Carla El-Mallah, Omar Obeid, Ola El-Saleh, Linda Smail, Dalia Haroun
Summary: The urinary excretion of calcium, magnesium, and phosphorus among Emirati schoolchildren was found to be similar to levels in other countries. Fluoride excretion suggests that Emirati children have a low risk of fluorosis. The slightly elevated level of urinary iodine excretion requires close monitoring of salt iodization to prevent harmful effects of iodine overconsumption.
Article
Pediatrics
Birtukan Shiferaw Ayalew, Seid Legesse Hassen, Tefera Alemu Marefiyaw, Mohammed Seid Yesuf, Daniel Dagne Abebe, Minwuyelet Maru Temesgen
Summary: The study revealed that the iodine deficiency rate among school-aged children was 18.6%, with a higher proportion of deficiency observed in females. This highlights the need for additional strategies to control iodine deficiency in this population.
Article
Biochemistry & Molecular Biology
Jingyi Luo, Chenyan Li, Xiaomei Zhang, Zhongyan Shan, Weiping Teng
Summary: The study established reference intervals for UIC/UCr in pregnant women, which may eliminate the effect of urine volume and more accurately reflect the actual prevalence of iodine deficiency. The prevalence of iodine deficiency in pregnant women may be overestimated using UIC as an indicator compared to UIC/UCr.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Nutrition & Dietetics
Chisom B. Ezemaduka Okoli, Henok G. Woldu, Catherine A. Peterson
Summary: The study examined the association between urinary iodine concentrations and insulin resistance in US adults, finding that low iodine status may increase the risk of developing insulin resistance, especially in females, which could potentially lead to prediabetes. Further investigation is needed to fully understand the implications of these findings.
Article
Nutrition & Dietetics
Aidy Gonzalez-Nunez, Pablo Garcia-Solis, Silvia G. Ramirez-Garcia, German Flores-Ramirez, Marcela Vela-Amieva, Victor J. Lara-Diaz, Augusto Rojas-Martinez
Summary: In Mexico, the median UIC of children aged 5 to 11 was 442 mg/L, showing a significant association with TSH levels, indicating potential effects on thyroid function. The study also identified high prevalences of overweight/obesity and enlarged waist circumference in children.
Article
Endocrinology & Metabolism
Xia Shen, Long Yang, Yuan-Yuan Liu, Xue-He Zhang, Ping Cai, Jian-Feng Huang, Lei Jiang
Summary: This study found a relationship between iodine status and metabolic disorders, with higher iodine status associated with higher prevalence of metabolic syndrome, while lower iodine status associated with lower prevalence of metabolic syndrome.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Diane E. Threapleton, Dagmar Waiblinger, Charles J. P. Snart, Elizabeth Taylor, Claire Keeble, Samina Ashraf, Shazia Bi, Ramzi Ajjan, Rafaq Azad, Neil Hancock, Dan Mason, Stephen Reid, Kirsten J. Cromie, Nisreen A. Alwan, Michael Zimmermann, Paul M. Stewart, Nigel A. B. Simpson, John Wright, Janet E. Cade, Laura J. Hardie, Darren C. Greenwood
Summary: This study in Bradford, UK, investigated the relationship between iodine intake in pregnant women and thyroid function, showing that intake was associated with markers such as urinary iodine concentration, thyroglobulin, and palpable goiter. High intake was linked to better thyroid health outcomes.
Article
Nutrition & Dietetics
Johannes Riis, Klaus M. Pedersen, Mathias B. Danielsen, Gustav V. B. Sorensen, Martin G. Jorgensen, Stine L. Andersen, Allan Carle, Inge B. Pedersen, Christian Torp-Pedersen, Stig Andersen
Summary: Long-term residency in an iodine-replete environment (Skagen) is associated with a lower risk of death and increased longevity compared to residency in an iodine-deficient environment (Randers) according to a 20-year follow-up study on participants.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Gastroenterology & Hepatology
Morten Mork, Stine Linding Andersen, Inge Sokilde Pedersen, Anja Ernst, Simon Lykkeboe, Henrik Bygum Krarup
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2020)
Article
Endocrinology & Metabolism
Stine Linding Andersen, Stig Andersen, Zeyan Liew, Peter Vestergaard, Soren Lundbye-Christensen, Thorkild I. A. Sorensen, Jorn Olsen
Summary: The study found no significant association between maternal thyroid disease during pregnancy and child overweight or obesity. However, it did identify a correlation between maternal thyroid disease and maternal adiposity.
CLINICAL ENDOCRINOLOGY
(2021)
Review
Endocrinology & Metabolism
Stine Linding Andersen, Kasper Krogh Nielsen, Soren Risom Kristensen
Summary: Pregnancy leads to physiological changes that can affect the risk of thrombosis and thyroid disease. The hypothesis suggests an association between thyroid disease and VTE in pregnant women, calling for further research.
Article
Endocrinology & Metabolism
Johannes Riis, Stine L. Andersen, Gustav Gade, Mathias B. Danielsen, Martin G. Jorgensen, Allan Carle, Christian Torp-Pedersen, Stig Andersen
Summary: The introduction of iodine fortification of salt in Denmark led to a transient rise in hyperthyroidism, particularly affecting older adults. This study found an association between hyperthyroidism and increased mortality in older adults with moderate iodine deficiency. Results emphasize the importance of cautious iodine supplementation and monitoring of iodine fortification programs.
CLINICAL ENDOCRINOLOGY
(2022)
Article
Endocrinology & Metabolism
Stine Linding Andersen, Anja Lisbeth Frederiksen, Astrid Bruun Rasmussen, Mette Madsen, Ann-Margrethe Ronholt Christensen
Summary: Pathogenic variants of PTH causing hypoparathyroidism are rare. In this case, the child was asymptomatic and there were discordant PTH results with different assays.
JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
(2022)
Article
Obstetrics & Gynecology
Lea L. H. Lunddorf, Andreas Ernst, Nis Brix, Linn H. Arendt, Stine L. Andersen, Jorn Olsen, Cecilia H. Ramlau-Hansen
Summary: This study found indications of earlier pubertal development in sons of mothers with hyperthyroidism. Further research is needed to investigate the observed sex-specific association.
FERTILITY AND STERILITY
(2022)
Article
Endocrinology & Metabolism
Louise Knosgaard, Stig Andersen, Annebirthe Bo Hansen, Anne Sorensen, Peter Vestergaard, Stine Linding Andersen
Summary: This study evaluated iodine status in Danish pregnant women and found that despite iodine fortification programs and supplement use, iodine intake was insufficient.
CLINICAL ENDOCRINOLOGY
(2023)
Letter
Medical Laboratory Technology
Stig Andersen, Johannes Riis, Jesper S. Karmisholt, Stine L. Andersen
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2023)
Article
Endocrinology & Metabolism
Louise Knosgaard, Stig Andersen, Annebirthe Bo Hansen, Peter Vestergaard, Stine Linding Andersen
Summary: This study found that maternal hypothyroidism, especially when TSH levels were above 10 mIU/L, was associated with adverse pregnancy outcomes. However, no significant association was found between thyroid autoimmunity and adverse pregnancy outcomes.
CLINICAL ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Nanna Maria Uldall Torp, Inge Bülow Pedersen, Allan Carle, Jesper Scott Karmisholt, Eva Ebbehoj, Diana Grove-Laugesen, Thomas Heiberg Brix, Steen Joop Bonnema, Bieke F. Schrijvers, Birte Nygaard, Lena Bjergved Sigurd, Ulla Feldt-Rasmussen, Marianne Klose, Ase Krogh Rasmussen, Stig Andersen, Stine Linding Andersen
Summary: A Danish multicenter study called 'Pregnancy Investigations on Thyroid Disease' (PRETHYR) was initiated in 2021 to collect detailed clinical data on pregnant women with hyperthyroidism and their offspring. As of November 1, 2022, 62 women have been included in the study, with 41.9% reporting current use of thyroid medication. This study's design and implementation are important for better management and control of hyperthyroidism in pregnancy.
Article
Endocrinology & Metabolism
Johannes Riis, Louise Westergaard, Jesper Karmisholt, Stine Linding Andersen, Stig Andersen
Summary: This study investigated the variation in thyroid function test results in older adults and younger adults. The results showed that the coefficients of variation for TSH, TT4, and TT3 were higher in older adults compared to younger adults. However, TT4 had comparable coefficients of variation between individuals in older adults, indicating that it could provide a reliable estimate of thyroid function.
CLINICAL ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Stine Linding Andersen, Niels Henrik Bruun, Peter Astrup Christensen, Simon Lykkeboe, Aase Handberg, Annebirthe Bo Hansen, Maja Hjelm Lundgaard, Louise Knosgaard, Nanna Maria Uldall Torp, Allan Carle, Jesper Karmisholt, Inge Buelow Pedersen, Peter Vestergaard, Stig Andersen
Summary: This study established and evaluated pregnancy-specific cut-offs for TPO-Ab and Tg-Ab, which are important for the classification of exposure in pregnancy and assessment of thyroid autoimmunity.
EUROPEAN THYROID JOURNAL
(2022)
Article
Endocrinology & Metabolism
J. Karmisholt, S. L. Andersen, I Bulow-Pedersen, A. Krejbjerg, B. Nygaard, A. Carle
Summary: This study aimed to investigate the timing and characteristics of adverse drug reactions in patients with Graves' hyperthyroidism (GH) treated with anti-thyroid drugs (ATD) for up to 48 months. The results showed that 10% of the patients experienced adverse drug reactions, with 75% of the cases occurring within the first 6 months of treatment. Skin reactions were the most common adverse reaction, comprising 68% of the registered reactions. After 24 months, no further adverse drug reactions were recorded when the methimazole dose was lowered to 5 mg/day.
EUROPEAN THYROID JOURNAL
(2022)
Article
Endocrinology & Metabolism
Maja Hjelm Lundgaard, Allan Carle, Ulla Birgitte Christiansen, Anne Sorensen, Soren Risom Kristensen, Stine Linding Andersen
Summary: This case report highlights the importance of thyroid function assessment in patients with unexplained abnormalities in the coagulation system. In this particular case, a prolonged APTT led to the diagnosis of autoimmune hypothyroidism in a young woman with severe placental dysfunction.
EUROPEAN THYROID JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Sadia Anjum, Hamile Ali, Faiza Naseer, Maisa S. Abduh, Halima Qadir, Salik Kakar, Yasir Waheed, Tahir Ahmad
Summary: This study demonstrates that avocado and papaya fruit juices can reduce the accumulation of cadmium in the liver, kidney, and hippocampal tissues, and upregulate the expression of antioxidant enzymes while reducing lipid peroxidation. Compared to avocado, papaya has a stronger potential for improving memory and learning, as well as reducing lipid peroxidation in various tissues.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Celio Junior da C. Fernandes, Gerson Santos de Almeida, Patricia Fretes Wood, Anderson M. Gomes, Fabio J. Bezerra, Jose C. S. Vieira, Pedro M. Padilha, Willian F. Zambuzzi
Summary: This study demonstrates the role of mechanosignaling in the promotion of an osteoblastic phenotype in response to zirconia exposure. The release of angiocrine factors modulated by mechanosignaling is crucial in creating a microenvironment that promotes wound healing and osseointegration. These findings highlight the importance of considering endothelial cell mechanosignaling in bone healing and osseointegration in the context of blood vessel effects.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Rehab I. Abdel-Karim, Rania K. Hashish, Dahlia I. Badran, Sally S. Mohammed, Noha A. Salem
Summary: The study found that chlorpyrifos has hepatotoxicity, while cerium oxide nanoparticles can alleviate this toxicity. Cerium oxide nanoparticles can protect the liver by reducing the expression of inflammatory and apoptotic proteins and increasing the activity of antioxidant enzymes.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tahani El Ayari, Raja Ben Ahmed, Zaineb Hammemi, Abdessalem Kouki, Emna Chelb, Salwa Nechi, Najoua Trigui El Menif
Summary: This study assessed the effects of samarium doped zinc oxide nanoparticles (Sm doped ZnO NPs) on the edible mussel Mytilus galloprovincialis and found that it led to a decrease in filtration rates and histopathological alterations in the gills, digestive glands, and gonads.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shanshan Niu, Zhangmin Wang, Xuebin Yin, Xiaodong Liu, Liqiang Qin, Muhammad Raza Farooq, Ofori Prince Danso, Zezhou Zhang, Qin Luo, Chenlu Sun, Jiaping Song
Summary: This study investigated the transport of selenium through the soil-crop-human chain in regions with different selenium levels. It found that the residents' dietary selenium intake was related to the selenium content in soil, with one village within the WHO recommended intake range while the other village was at risk of selenium deficiency. There were significant positive correlations between residents' dietary selenium intake and the three selenium biomarkers.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Sanaz Salaramoli, Hamid Reza Joshaghani, Ali Shoeibi, Seyed Isaac Hashemy
Summary: The study suggests that serum levels of selenium and selenoprotein P may serve as biomarkers or risk factors for Parkinson's disease. Additionally, there is a correlation between alpha-synuclein levels and disease stage. Further research is needed to understand the role of selenoprotein S in reducing alpha-synuclein aggregation.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Motozumi Ando, Keiko Suzuki, Riko Kitamoto, Ayako Nakayama, Norio Watanabe, Masami Kawahara
Summary: C57BL/6 mice and BALB/c mice showed different expression profiles of selenoprotein P after a high-fat diet (HFD). C57BL/6 mice in the HFD group had higher body weight, fasting plasma glucose levels, and plasma selenoprotein P levels compared to the ND group. However, BALB/c mice did not show significant differences in fasting plasma selenoprotein P levels between the HFD and ND groups.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ruihan Song, Huanhuan Chen, Runqing Zhan, Miaomiao Han, Longzhu Zhao, Xiaoli Shen
Summary: This study aims to investigate the protective effects of Vitamin E (Vit E) on manganese (Mn)-induced nigrostriatal system lesions. The results demonstrate that Vit E improves behavioral disorders, attenuates the loss of nigral dopaminergic neurons, and restores mitochondrial function. Additionally, the protective effect of Vit E may be associated with the upregulation of CHRM1 and KCNJ4 mRNA.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jose Luan da Paixao Teixeira, Ana Paula Rebellato, Maria Isabel Andrekowisk Fioravanti, Raquel Fernanda Milani, Marcelo Antonio Morgano
Summary: The study aimed to determine the total Se content and bioaccessibility in commercial plant-based beverages, with results showing that only one beverage made from organic cashew nuts could meet the recommended Se intake for different populations. High bioacessibility percentages were observed in the beverages.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Andreas F. Lehner, Sarah Rebolloso, Paul P. Calle, Karen Ingerman, Gregory A. Lewbart, Juan Pablo Munoz-Perez, Carlos A. Valle, John P. Buchweitz
Summary: The dried blood spot (DBS) technology is useful for storing blood samples from wildlife, and this study developed methods for measuring several important elements in DBS and used them for health assessments of Galapagos land iguanas. The results showed that the DBS samples accurately reflected the concentrations of various elements compared to plasma samples, with some divergences observed between different species.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Zhou, Chunbei Zhou, Jun Xie, Fei Luo, Ning Yao
Summary: The study illustrates the changes in iodized salt usage, goiter rate, and median urinary iodine concentration in school-aged children in Chongqing over the past 21 years. Adequate iodized salt consumption can eliminate iodine deficiency disorders in children, but excessive iodine intake from salt can lead to high urinary iodine excretion and even goiter. Continuous monitoring and adjustment of iodine fortification levels in household table salt is crucial.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Agustin B. Actis Dato, Valeria R. Martinez, Jorge O. Velez Rueda, Enrique L. Portiansky, Veronica De Giustu, Evelina G. Ferrer, Patricia A. M. Williams
Summary: The zinc coordination complex ZnMD, synthesized in this study, showed promising effects in treating hypertension and cardiac hypertrophy. It was more effective than the antihypertensive drug MD in reducing blood pressure and preventing myocardial hypertrophy. ZnMD also exhibited protective effects on the heart by reducing oxidative damage and regulating the expression of oxidative enzymes. These findings suggest that ZnMD has the potential to be developed as a therapeutic drug for hypertension and cardiac dysfunction.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mina Sarani, Maryam Roostaee, Mahboubeh Adeli-Sardou, Davood Kalantar-Neyestanaki, Seyed Amin Ayatollahi Mousavi, Azam Amanizadeh, Mahmood Barani, Alireza Amirbeigi
Summary: This study successfully synthesized nano bismuth oxide using green synthesis methods. The nano particles doped with silver and copper demonstrated excellent antibacterial properties and selective cytotoxicity against cancer cells. These findings have important implications for biomedical and therapeutic applications.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mona Abdel-Rahman, Heba M. Elmasry, Omar A. Ahmed-Farid, Sherein M. Hegazy, Mohamed M. Rezk
Summary: This study investigates the neuro effects of lanthanides on different brain areas in rats and finds that they can distribute and accumulate in various brain regions. Treatment with cerium nanoparticles or lanthanum causes a significant decrease in norepinephrine, dopamine, serotonin, and GABA, accompanied by a significant increase in 5-hydroxyl indoleacetic acid levels. Moreover, cerium nanoparticles exhibit high activity in scavenging free radicals.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mahshid Deldar Abad Paskeh, Nahid Babaei, Mehrdad Hashemi, Abbas Doosti, Kiavash Hushmandi, Maliheh Entezari, Saeed Samarghandian
Summary: The combination of curcumin, vitamins D and E with Fe2O3-NPs and MnO2-NPs has shown to improve semen parameters and reduce apoptosis in germ cells in rats with testicular hyperthermia. This study suggests that this combination therapy may have a positive effect on fertility and decreasing the toxic effects of nanoparticles.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
