Review
Food Science & Technology
Xue Li, Binbin Nian, Ruizhi Li, Xinyu Cao, Yanjun Liu, Yuanfa Liu, Yong-Jiang Xu
Summary: This article conducted a meta-analysis to assess the effects of fasting on patients with metabolic syndrome (MS). The results showed that fasting significantly reduced body weight, BMI, body fat percentage, insulin level, and HOMA-IR in patients with MS, while having no effect on glucose, blood pressure, and lipids profile.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Endocrinology & Metabolism
Yue Liu, Huijun Zhuang, Na Han, Yuxing Yang, Qiao Zhang, Nianchun Peng, Ying Hu, Lixin Shi, Hong Li
Summary: This study investigated the incidence of metabolic syndrome (MS) in people over 40 years of age with normal blood glucose levels in Guiyang's urban areas and determined the effective glycemic cutoff value for predicting MS. The results showed a correlation between increased fasting plasma glucose (FPG) and the incidence of MS, even within the normal range. The study suggests that FPG testing can be used not only for diagnosing diabetes but also as a cost-effective screening method for predicting the development of MS in the general Chinese population.
DIABETES METABOLIC SYNDROME AND OBESITY
(2023)
Article
Health Care Sciences & Services
Maria Judith Rios-Lugo, Ana Gabriela Palos-Lucio, Claudia Ines Victoria-Campos, Angel Lugo-Trampe, Karina Del Carmen Trujillo-Murillo, Maximiliano Arahon Lopez-Garcia, Marisol Espinoza-Ruiz, Elizabeth Teresita Romero-Guzman, Hector Hernandez-Mendoza, Consuelo Chang-Rueda
Summary: A study conducted in southern Mexico found a specific association between fasting plasma glucose levels and serum selenium levels in women.
Article
Nutrition & Dietetics
Izzah Vasim, Chaudry N. Majeed, Mark D. DeBoer
Summary: Given the strain of the obesity epidemic on public health outcomes, new approaches to weight control are necessary. Intermittent fasting, with its beneficial metabolic effects, is an option to consider for individuals with unhealthy weight gain patterns. However, further research is needed for long-term outcomes and it should be avoided in specific health conditions.
Article
Biochemistry & Molecular Biology
Holger Steinbrenner, Leonidas H. H. Duntas, Margaret P. P. Rayman
Summary: This review discusses the role of selenium in T2DM and its metabolic co-morbidities, emphasizing the relevance of inflammation and oxidative stress. It describes the epidemiology of selenium studies in diabetes and explains the interaction between selenium status and glucose control. According to current research, dietary selenium supplementation does not appear to be a major causal factor for the development of T2DM.
Article
Endocrinology & Metabolism
Ri Liu, Lishu Gao, Lu Guo, Wenqi Xu, Shouling Wu, Dehu Tian
Summary: This study investigates the impact of FPG variability on osteoporotic fractures in the community population. By analyzing participants from three consecutive surveys, it is found that increased FPG variability is associated with an increased risk of osteoporotic fractures.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Deirdre K. Tobias, Samia Mora, Subodh Verma, Filio Billia, Julie E. Buring, Patrick R. Lawler
Summary: The study found that fasting was associated with lower plasma BCAA levels in women without metabolic syndrome or T2D, but had no significant impact on women with Type 2 diabetes. These results suggest that impaired BCAA metabolism may be related to the pathophysiology of T2D.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Article
Nutrition & Dietetics
Josip Vrdoljak, Marko Kumric, Marino Vilovic, Dinko Martinovic, Veljko Rogosic, Josip A. Borovac, Tina Ticinovic Kurir, Josko Bozic
Summary: Metabolic syndrome is a group of metabolic abnormalities that have a high prevalence and economic burden worldwide. Fasting has emerged as a dietary method for controlling metabolic risk factors, although the effects on humans are still unclear. Preclinical studies have shown positive effects on gut microbiota, glucose and insulin metabolism, weight and visceral fat, and lipid metabolism. However, results from human studies are conflicting and more research is needed.
Article
Medicine, Research & Experimental
Leandro Ceotto Freitas-Lima, Alexandre Budu, Gabriel Rufino Estrela, Thais Alves-Silva, Mauro Sergio Perilhao, Adriano Cleis Arruda, Ronaldo Carvalho Araujo
Summary: The absence of kinin B1 receptor (B1R) in mice modulates the metabolic shift under fasting conditions by reducing energy expenditure. The lack of B1R leads to a preference for carbohydrates as an energy source and increased serum triglycerides concentration. Enzymatic expression of glycolysis and lipolysis pathways is increased in fed B1KO animals, but no changes occur in gluconeogenesis, glyceroneogenesis, and ketogenesis pathways under fasting, indicating a lack of metabolic flexibility.
Article
Biochemistry & Molecular Biology
Teresa Urbano, Tommaso Filippini, Daniela Lasagni, Tiziana De Luca, Sabrina Sucato, Elisa Polledri, Francesco Bruzziches, Marcella Malavolti, Claudia Baraldi, Annalisa Santachiara, Thelma A. Pertinhez, Roberto Baricchi, Silvia Fustinoni, Marco Vinceti
Summary: The study aimed to assess urinary selenium excretion and dietary selenium intake in 137 healthy non-smoking blood donors. Results showed a correlation between urinary selenium and dietary selenium, but divergent associations with health endpoints. Higher selenium exposure was found to be adversely associated with blood glucose levels and lipid profile, even within tolerable upper intake levels.
Article
Endocrinology & Metabolism
Jung A. Kim, Ji Sung Lee, Eyun Song, Eun Roh, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Summary: This study examined the relationship between fasting plasma glucose variability and osteoporotic fractures in individuals without diabetes using a nationwide cohort database. The results suggest that FPG variability may be an independent risk factor for osteoporotic fractures in the general population without diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Jung A. Kim, Ji Sung Lee, Eyun Song, Eun Roh, Ji Hee Yu, Nam Hoon Kim, Hye Jin Yoo, Ji A. Seo, Sin Gon Kim, Nan Hee Kim, Sei Hyun Baik, Kyung Mook Choi
Summary: Although previous studies have linked long-term glucose variability to osteoporosis, this study is the first to investigate the relationship between glucose variability and fractures in individuals without diabetes. The results suggest that fasting plasma glucose variability may be an independent risk factor for osteoporotic fractures in the general population without diabetes.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Federico Oldoni, Kevin Bass, Julia Kozlitina, Hannah Hudson, Lisa M. Shihanian, Viktoria Gusarova, Jonathan C. Cohen, Helen H. Hobbs
Summary: Plasma A8 levels vary significantly across different racial/ethnic groups and are associated with BMI, fasting glucose, insulin, and TG levels. However, genetic variants in the A8 locus do not appear to have a causal relationship with the metabolic phenotypes associated with A8 levels.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Endocrinology & Metabolism
Leweihua Lin, Tuanyu Fang, Lu Lin, Qianying Ou, Huachuan Zhang, Kaining Chen, Huibiao Quan
Summary: This study identified genetic variants associated with 2-hour postprandial glucose, glycosylated hemoglobin, and body mass index in prediabetes patients from Hainan.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Anna Kokkinopoulou, Niki Katsiki, Ioannis Pagkalos, Nikolaos E. Rodopaios, Alexandra-Aikaterini Koulouri, Eleni Vasara, Sousana K. Papadopoulou, Petros Skepastianos, Emmanouil Dermitzakis, Maria Hassapidou, Anthony G. Kafatos
Summary: The study investigated the effects of Christian Orthodox fasting on body composition, dietary intake, and metabolic syndrome in postmenopausal women. The findings showed that fasting women had higher fat free mass, hip circumference, and diastolic blood pressure. They also consumed less fat, saturated and unsaturated fat, trans fatty acids, and cholesterol. Non-fasters had a higher prevalence of metabolic syndrome and its components. Overall, periodic abstinence from certain foods may protect postmenopausal women from metabolic syndrome.
Article
Endocrinology & Metabolism
Zheping Yuan, Chengguo Liu, Yiping Tian, Xuhui Zhang, Huaizhuang Ye, Lifeng Jin, Liansheng Ruan, Zhanhang Sun, Yimin Zhu
ANNALS OF NUTRITION AND METABOLISM
(2016)
Article
Oncology
Chunxiao Xu, Dan Zhou, Feixia Pan, Yi Liu, Dandan Zhang, Aifen Lin, Xiaoping Miao, Yaqin Ni, Duo Lv, Shuai Zhang, Xiaobo Li, Yimin Zhu, Maode Lai
Review
Medicine, General & Internal
Yi-Ping Tian, Yi-Min Zhu, Xiao-Hui Sun, Mao-De Lai
CHINESE MEDICAL JOURNAL
(2016)
Review
Public, Environmental & Occupational Health
Ruizhi Zheng, Dan Zhou, Yimin Zhu
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2016)
Article
Gastroenterology & Hepatology
Yiping Tian, Feixia Pan, Xiaohui Sun, Meifu Gan, Aifen Lin, Dandan Zhang, Yimin Zhu, Maode Lai
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
(2017)
Article
Nutrition & Dietetics
Ruizhi Zheng, Chengguo Liu, Chunmei Wang, Biao Zhou, Yi Liu, Feixia Pan, Ronghua Zhang, Yimin Zhu
Article
Genetics & Heredity
Duo Lv, Dan Zhou, Yan Zhang, Shuai Zhang, Yi-Min Zhu
Article
Genetics & Heredity
Xiaohui Sun, Yiping Tian, Jianming Wang, Zeyuan Sun, Yimin Zhu
BMC MEDICAL GENOMICS
(2020)
Article
Environmental Sciences
Ge Chen, Qian Yi, Leying Hou, Shenghan Peng, Mengya Fan, Peige Song, Yimin Zhu
Summary: The study found that hypertriglyceridemic-waist (HTW) and its dynamic transitions were associated with an increased risk of incident type 2 diabetes mellitus (T2DM) among middle-aged and older Chinese. Individuals with abnormal HTW phenotypes, such as NTEW/ETNW and ETEW, had a significantly higher risk of developing T2DM compared to those with normal HTW phenotype (NTNW). Transitioning to adverse metabolic states from normal or less severe states was also found to be a risk factor for T2DM.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Cell Biology
Yiran Zhang, Qi Zheng, Ruoshi Chen, Xiaoyi Dai, Yimin Zhu, Liang Ma
Summary: The study aimed to investigate the association of NFE2L2 gene polymorphisms with acute type A aortic dissection (AAAD) in a Han Chinese population. The CC genotypes of rs2364723 and rs35652124 were identified as risk factors for AAAD, and were associated with increased maximum ascending aorta diameter. Patients with rs2364723 CC genotype had a higher incidence of coronary artery involvement, while patients with rs35652124 CC genotype had a higher incidence of brain ischemia.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
(2021)
Article
Nutrition & Dietetics
Xuhui Zhang, Qiannan Chen, Xiaohui Sun, Qiong Wu, Zongxue Cheng, Qingguo Lv, Jiaqiang Zhou, Yimin Zhu
Summary: Previous studies have shown that abdominal adipose tissue deposition is related to cardiometabolic abnormalities. This study found that higher levels of visceral adipose tissue (VAT) were associated with metabolic abnormalities in both males and females, while higher levels of subcutaneous adipose tissue (SAT) increased the risk of metabolic abnormalities only in females with a BMI greater than 24 kg/m(2). Additionally, VAT was a better predictor of metabolic abnormalities compared to BMI and waist circumference (WC).
NUTRITION & METABOLISM
(2022)
Article
Geriatrics & Gerontology
Zongxue Cheng, Di He, Jun Li, Qiong Wu, Zuyun Liu, Yimin Zhu
Summary: Systemic inflammation indicators CRP and WBC are associated with frailty progression, accelerating the rate of increase in frailty in younger individuals, highlighting the importance of systemic inflammation for identifying those at high risk of rapid frailty progression.
Article
Geriatrics & Gerontology
Di He, Yiwen Qiu, Mengsha Yan, Tianjing Zhou, Zongxue Cheng, Jun Li, Qiong Wu, Zuyun Liu, Yimin Zhu
Summary: Metabolically unhealthy overweight/obesity and normal weight individuals, but not metabolically healthy overweight/obesity, have an accelerated frailty progression compared to metabolically healthy normal weight individuals. Regardless of obesity status, transitioning from a healthy metabolic status to an unhealthy metabolic status accelerates frailty progression compared to stable metabolically healthy normal weight individuals. This emphasizes the importance of metabolic status in frailty progression and suggests the stratified management of obesity based on metabolic status.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Public, Environmental & Occupational Health
Xingqi Cao, Xueqin Li, Jingyun Zhang, Xiaoyi Sun, Gan Yang, Yining Zhao, Shujuan Li, Emiel Hoogendijk, Xiaofeng Wang, Yimin Zhu, Heather Allore, Thomas M. Gill, Zuyun Liu
Summary: Frailty is significantly associated with higher risks of multiple adverse outcomes in middle-aged adults with prediabetes, including type 2 diabetes, diabetes-related diseases, and all-cause mortality. It is suggested that assessment of frailty should be incorporated into routine care for adults with prediabetes to improve resource allocation and reduce diabetes-related burden.
JMIR PUBLIC HEALTH AND SURVEILLANCE
(2023)
Article
Public, Environmental & Occupational Health
Shuchang Chen, Yaqin Ni, Lei Zhang, Liya Kong, Luying Lu, Zhangping Yang, Luoxian Yang, Xuhui Zhang, Yimin Zhu
Article
Biochemistry & Molecular Biology
Sadia Anjum, Hamile Ali, Faiza Naseer, Maisa S. Abduh, Halima Qadir, Salik Kakar, Yasir Waheed, Tahir Ahmad
Summary: This study demonstrates that avocado and papaya fruit juices can reduce the accumulation of cadmium in the liver, kidney, and hippocampal tissues, and upregulate the expression of antioxidant enzymes while reducing lipid peroxidation. Compared to avocado, papaya has a stronger potential for improving memory and learning, as well as reducing lipid peroxidation in various tissues.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Celio Junior da C. Fernandes, Gerson Santos de Almeida, Patricia Fretes Wood, Anderson M. Gomes, Fabio J. Bezerra, Jose C. S. Vieira, Pedro M. Padilha, Willian F. Zambuzzi
Summary: This study demonstrates the role of mechanosignaling in the promotion of an osteoblastic phenotype in response to zirconia exposure. The release of angiocrine factors modulated by mechanosignaling is crucial in creating a microenvironment that promotes wound healing and osseointegration. These findings highlight the importance of considering endothelial cell mechanosignaling in bone healing and osseointegration in the context of blood vessel effects.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Rehab I. Abdel-Karim, Rania K. Hashish, Dahlia I. Badran, Sally S. Mohammed, Noha A. Salem
Summary: The study found that chlorpyrifos has hepatotoxicity, while cerium oxide nanoparticles can alleviate this toxicity. Cerium oxide nanoparticles can protect the liver by reducing the expression of inflammatory and apoptotic proteins and increasing the activity of antioxidant enzymes.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tahani El Ayari, Raja Ben Ahmed, Zaineb Hammemi, Abdessalem Kouki, Emna Chelb, Salwa Nechi, Najoua Trigui El Menif
Summary: This study assessed the effects of samarium doped zinc oxide nanoparticles (Sm doped ZnO NPs) on the edible mussel Mytilus galloprovincialis and found that it led to a decrease in filtration rates and histopathological alterations in the gills, digestive glands, and gonads.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shanshan Niu, Zhangmin Wang, Xuebin Yin, Xiaodong Liu, Liqiang Qin, Muhammad Raza Farooq, Ofori Prince Danso, Zezhou Zhang, Qin Luo, Chenlu Sun, Jiaping Song
Summary: This study investigated the transport of selenium through the soil-crop-human chain in regions with different selenium levels. It found that the residents' dietary selenium intake was related to the selenium content in soil, with one village within the WHO recommended intake range while the other village was at risk of selenium deficiency. There were significant positive correlations between residents' dietary selenium intake and the three selenium biomarkers.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Sanaz Salaramoli, Hamid Reza Joshaghani, Ali Shoeibi, Seyed Isaac Hashemy
Summary: The study suggests that serum levels of selenium and selenoprotein P may serve as biomarkers or risk factors for Parkinson's disease. Additionally, there is a correlation between alpha-synuclein levels and disease stage. Further research is needed to understand the role of selenoprotein S in reducing alpha-synuclein aggregation.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Motozumi Ando, Keiko Suzuki, Riko Kitamoto, Ayako Nakayama, Norio Watanabe, Masami Kawahara
Summary: C57BL/6 mice and BALB/c mice showed different expression profiles of selenoprotein P after a high-fat diet (HFD). C57BL/6 mice in the HFD group had higher body weight, fasting plasma glucose levels, and plasma selenoprotein P levels compared to the ND group. However, BALB/c mice did not show significant differences in fasting plasma selenoprotein P levels between the HFD and ND groups.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ruihan Song, Huanhuan Chen, Runqing Zhan, Miaomiao Han, Longzhu Zhao, Xiaoli Shen
Summary: This study aims to investigate the protective effects of Vitamin E (Vit E) on manganese (Mn)-induced nigrostriatal system lesions. The results demonstrate that Vit E improves behavioral disorders, attenuates the loss of nigral dopaminergic neurons, and restores mitochondrial function. Additionally, the protective effect of Vit E may be associated with the upregulation of CHRM1 and KCNJ4 mRNA.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jose Luan da Paixao Teixeira, Ana Paula Rebellato, Maria Isabel Andrekowisk Fioravanti, Raquel Fernanda Milani, Marcelo Antonio Morgano
Summary: The study aimed to determine the total Se content and bioaccessibility in commercial plant-based beverages, with results showing that only one beverage made from organic cashew nuts could meet the recommended Se intake for different populations. High bioacessibility percentages were observed in the beverages.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Andreas F. Lehner, Sarah Rebolloso, Paul P. Calle, Karen Ingerman, Gregory A. Lewbart, Juan Pablo Munoz-Perez, Carlos A. Valle, John P. Buchweitz
Summary: The dried blood spot (DBS) technology is useful for storing blood samples from wildlife, and this study developed methods for measuring several important elements in DBS and used them for health assessments of Galapagos land iguanas. The results showed that the DBS samples accurately reflected the concentrations of various elements compared to plasma samples, with some divergences observed between different species.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Zhou, Chunbei Zhou, Jun Xie, Fei Luo, Ning Yao
Summary: The study illustrates the changes in iodized salt usage, goiter rate, and median urinary iodine concentration in school-aged children in Chongqing over the past 21 years. Adequate iodized salt consumption can eliminate iodine deficiency disorders in children, but excessive iodine intake from salt can lead to high urinary iodine excretion and even goiter. Continuous monitoring and adjustment of iodine fortification levels in household table salt is crucial.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Agustin B. Actis Dato, Valeria R. Martinez, Jorge O. Velez Rueda, Enrique L. Portiansky, Veronica De Giustu, Evelina G. Ferrer, Patricia A. M. Williams
Summary: The zinc coordination complex ZnMD, synthesized in this study, showed promising effects in treating hypertension and cardiac hypertrophy. It was more effective than the antihypertensive drug MD in reducing blood pressure and preventing myocardial hypertrophy. ZnMD also exhibited protective effects on the heart by reducing oxidative damage and regulating the expression of oxidative enzymes. These findings suggest that ZnMD has the potential to be developed as a therapeutic drug for hypertension and cardiac dysfunction.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mina Sarani, Maryam Roostaee, Mahboubeh Adeli-Sardou, Davood Kalantar-Neyestanaki, Seyed Amin Ayatollahi Mousavi, Azam Amanizadeh, Mahmood Barani, Alireza Amirbeigi
Summary: This study successfully synthesized nano bismuth oxide using green synthesis methods. The nano particles doped with silver and copper demonstrated excellent antibacterial properties and selective cytotoxicity against cancer cells. These findings have important implications for biomedical and therapeutic applications.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mona Abdel-Rahman, Heba M. Elmasry, Omar A. Ahmed-Farid, Sherein M. Hegazy, Mohamed M. Rezk
Summary: This study investigates the neuro effects of lanthanides on different brain areas in rats and finds that they can distribute and accumulate in various brain regions. Treatment with cerium nanoparticles or lanthanum causes a significant decrease in norepinephrine, dopamine, serotonin, and GABA, accompanied by a significant increase in 5-hydroxyl indoleacetic acid levels. Moreover, cerium nanoparticles exhibit high activity in scavenging free radicals.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mahshid Deldar Abad Paskeh, Nahid Babaei, Mehrdad Hashemi, Abbas Doosti, Kiavash Hushmandi, Maliheh Entezari, Saeed Samarghandian
Summary: The combination of curcumin, vitamins D and E with Fe2O3-NPs and MnO2-NPs has shown to improve semen parameters and reduce apoptosis in germ cells in rats with testicular hyperthermia. This study suggests that this combination therapy may have a positive effect on fertility and decreasing the toxic effects of nanoparticles.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)