期刊
FRONTIERS IN BIOSCIENCE-LANDMARK
卷 18, 期 -, 页码 241-278出版社
FRONTIERS IN BIOSCIENCE INC
DOI: 10.2741/4098
关键词
Mitochondria; Oxidative Phosphorylation; Mitochondrial Disease; Saccharomyces cerevisiae; Review
资金
- American Heart Association [10PRE3280013]
- National Institutes of Health [R00HL089185]
Mitochondria participate in a variety of cellular functions. As such, mitochondrial diseases exhibit numerous clinical phenotypes. Because mitochondrial functions are highly conserved between humans and Saccharomyces cerevisiae, yeast are an excellent model to study mitochondrial disease, providing insight into both physiological and pathophysiological processes.
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