Article
Food Science & Technology
Gerard M. O'Brien, Boon Jin Lim, Yi Lin Ong, Kian Han Toh, Cong Shan Sim, Rose Koh
Summary: Most of the fresh cassava roots and cassava products purchased in Singapore during 2016-2017 exceeded the Codex Alimentarius limit for 'sweet' (boil-and-eat) cassava, but the cyanogenic potential in all cassava flour and ready-to-eat chips was below 20 mg kg(-1).
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Environmental
Xun Tan, Yijun Chen, Qiang Xue, Xingxing He, MingLi Wei, Ping Wang, Lei Liu, Jiangshan Li, Xiande Xie
Summary: Fenton oxidation can effectively improve the dewaterability of aged sludge. Quantification of the addition of optimal reagents is central to the conditioning and dewatering of aged sludge, with improving accuracy significant for cost effectiveness. By investigating the physicochemical characteristics and interactions among critical indicators of aged sludge, a new reagent addition quantification method and empirical model were developed to understand the optimal reagent addition.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Zhejun Yang, Ren Zhang, Hui Chen, Jilie Kong
Summary: Sodium thiocyanate is a naturally antibacterial component in milk, but excessive consumption may pose potential risks to human health. In this study, a robust and cost-effective method based on surface-enhanced Raman spectroscopy (SERS) was developed for NaSCN detection using paper substrates deposited with in situ reduced Ag nanoparticles. The proposed method exhibited high sensitivity, a wide linear range, and good reproducibility, making it suitable for NaSCN detection and milk analysis.
Article
Chemistry, Multidisciplinary
Daniel Tabian, Diana Bulgaru Iliescu, Madalina Maria Diac, Mihaela Badea, Sebastian Ionut Toma, Gabi Drochioiu
Summary: An original kinetic spectrophotometric procedure was developed for the determination of hydrogen cyanide (HCN) in the whole blood of fire victims. The method proved to be accurate, sensitive, and selective, and has been successfully applied to the analysis of blood samples from several fire victims.
APPLIED SCIENCES-BASEL
(2022)
Article
Acoustics
Yongheng Zhong, Tao Xu, Shengyang Ji, Xiaodan Wu, Tian Zha, Shimin Li, Peng Zhang, Kaimian Li, Baiyi Lu
Summary: The study found that ultrasonic pretreatment (UPT) is an effective way to remove cyanide from cassava in a short period of time, enhancing the safety of cassava. UPT can improve the processing of cassava by directly eliminating hydrogen cyanide and indirectly degrading cyanogenic glycosides, while also promoting enzymatic hydrolysis.
ULTRASONICS SONOCHEMISTRY
(2021)
Article
Chemistry, Organic
Matthew A. Sguazzin, Jarrod W. Johnson, Jakob Magolan
Summary: HFIPS is a bench-stable solid that reacts readily with a wide variety of alcohols, amines, phenols, and anilines under mild reaction conditions, producing hexafluoroisopropanol as the sole byproduct. The reaction products can often be isolated in high purity after an aqueous workup and removal of solvents by evaporation.
Article
Chemistry, Inorganic & Nuclear
Nidhi Kumari, Anup Mahata, Biswarup Chakraborty
Summary: The global consumption of triphenylphosphine (Ph3P) for organic synthesis and the production of triphenylphosphine oxide (Ph3PO) waste is high. Recycling Ph3PO and using it as a reaction mediator has gained attention. In this study, a phosphamide analogue to Ph3PO has been synthesized and used as a heterogeneous mediator for the Appel reaction with successful catalytic conversion and recovery. This approach showcases the potential use of phosphamides in phosphorus-mediated reactions.
INORGANIC CHEMISTRY
(2023)
Article
Medicine, Legal
Daniel Tabian, Diana Bulgaru Iliescu, Tatiana Iov, Barabas Barna, Sebastian Ionut Toma, Gabi Drochioiu
Summary: This report presents a case of an 80-year-old man who died from a fire-related incident involving vegetation debris and household waste. While the main cause of death was attributed to CO poisoning and severe burns, the additive effect of HCN was also highlighted. The study results suggest that burning garbage in open space fires may increase the risk of HCN production.
JOURNAL OF FORENSIC SCIENCES
(2021)
Article
Biochemical Research Methods
Gerrit Haeger, Johannes Bongaerts, Petra Siegert
Summary: An improved and convenient ninhydrin assay for aminoacylase activity measurements was developed using the commercial EZ NinTM reagent. The addition of DMSO enhanced the solubility of Ruhemann's purple, and the use of a basic, aqueous buffer improved its stability. Furthermore, an acidic protocol for quantification of lysine was developed. The assay allows for parallel processing in a 96-well format.
ANALYTICAL BIOCHEMISTRY
(2022)
Review
Biotechnology & Applied Microbiology
Toon Coelmont, Pieter Van Gaelen, Ilse Smets
Summary: This paper reviews current methods for monitoring hydrolysis activity of enzymes in biological wastewater treatment. It highlights the relevant methods for different types of hydrolysis and discusses the use of substrates mimicking those present in wastewater. The review concludes that using relevant substrates with fluorophores has the highest potential for accurate hydrolysis quantification.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Kyohei Nakano, Iat Wai Leong, Daisuke Hashizume, Kirill Bulgarevich, Kazuo Takimiya, Yusuke Nishiyama, Toshio Yamazaki, Keisuke Tajima
Summary: This study develops a new synthetic route to synthesize several new BIT derivatives. The properties of these derivatives are investigated experimentally and computationally, revealing rapid tautomerization in solution and solid state. It is also found that one of the derivatives exhibits good charge transport performance in an organic field effect transistor.
Article
Green & Sustainable Science & Technology
Kunlin Li, Yu Tian, Xie Tang, Peng Gao, Xiao Peng, Ping Ning, Chi Wang, Fei Wang, Xin Sun, Kai Li
Summary: Efficient catalysts are needed for the simultaneous removal of hydrogen cyanide (HCN) and carbonyl sulfide (COS). In this study, ZnNiAl compounds doped with rare earth metals were synthesized and used for the hydrolysis of HCN and COS. The results showed that Ce doping changed the chemical state and electronic structure of ZnNiAl, resulting in abundant active species for the adsorption and dissociation of HCN and COS. Ce doping also significantly improved the catalytic performance of ZnNiAl.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Chemistry, Analytical
Josiele A. M. Conrado, Diele A. G. Araujo, Joao Flavio da Silveira Petruci
Summary: This study presents a novel analytical method for the selective and sensitive determination of cyanide. The method involves analyte volatilization, pre-concentration via single-drop microextraction (SDME) using a selective reagent, and colorimetric quantification using a paper-based analytical device. Under optimized conditions, the method demonstrates a suitable linear relationship ranging from 26 to 286 μg/L and a limit of detection of 5 μg/L.
ANALYTICA CHIMICA ACTA
(2023)
Article
Environmental Sciences
Qiang Liu, Yating Luo, Jiyan Shi
Summary: Currently, the cyanide gold extraction process remains the main technology for gold production. The cyanide tailings generated during this process, which contain highly toxic substances, pose potential environmental risks. In this study, the effects of elution methods, operating time, tailings/water ratios, and reagent types on the elution rates of cyanide were investigated. A composite elution method was developed and extended for engineering. The results showed that the optimal elution conditions were determined to be stirring elution, a tailings/water ratio of 1:1, and an operating time of 10-20 minutes. Additionally, four reagents were selected for further composite elution, resulting in a high cyanide elution rate. The combination of reagent elution and positive pressure filtration improved cyanide elution efficiency. The effluent can be reused directly or after further treatment, achieving zero discharge of effluents and solid wastes. These findings provide important support for the engineering treatment of cyanide tailings.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2022)
Article
Chemistry, Analytical
Xiaoyun Hu, Tianshi Zhang, Jiguang Li, Zhiwei Ma, Da Lei, Baiyi Zu, Xincun Dou
Summary: A new solvent induction strategy was proposed in this study to achieve sensitive and robust colorimetry, providing a new approach for the design of high-performance chemical sensors.
ANALYTICAL CHEMISTRY
(2022)
Article
Medicine, Legal
Daniel Tabian, Diana Bulgaru Iliescu, Tatiana Iov, Barabas Barna, Sebastian Ionut Toma, Gabi Drochioiu
Summary: This report presents a case of an 80-year-old man who died from a fire-related incident involving vegetation debris and household waste. While the main cause of death was attributed to CO poisoning and severe burns, the additive effect of HCN was also highlighted. The study results suggest that burning garbage in open space fires may increase the risk of HCN production.
JOURNAL OF FORENSIC SCIENCES
(2021)
Article
Environmental Sciences
Daniel Tabian, Gabi Drochioiu, Simona Irina Damian, Nona Girlescu, Oana Toma Gradinaru, Sebastian Ionut Toma, Diana Bulgaru Iliescu
Summary: This study presents a case of a room fire victim in which the concentrations of HCN and COHb were evaluated to analyze their contribution to the mechanism of death. The findings suggest that toxic concentrations of HCN can be interpreted as a vital sign, indicating a contributive effect of HCN in the mechanism of death.
Article
Biochemistry & Molecular Biology
Cosmin Stefan Mocanu, Gabi Drochioiu
Summary: NAP peptide, as a small active fragment of the activity-dependent neuroprotective protein, could provide neuro and cognitive protection of the brain at low concentrations. The use of sonication in synthesis of NAP peptide conjugate with ASA allows for faster synthesis and potential benefits in Alzheimer's disease therapy pathways.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2021)
Article
Medicine, Legal
Milazim Tahirukaj, Blerim Olluri, Andriana Surleva
Summary: The reliability of forensic evidences for the presence of inorganic gunshot residue on a given surface depends strongly on the performance of the SEM-EDS method. By studying the effect of SEM/EDS working parameters, optimal parameters were established and the method was validated. The method was found to be capable of providing legal proof for the existence of iGSR on a specific surface, with 14% positive results found in samples from 144 cases analyzed over the past 3 years.
JOURNAL OF FORENSIC SCIENCES
(2021)
Article
Environmental Sciences
Radu Necula, Marius Zaharia, Alina Butnariu, Maria-Magdalena Zamfirache, Andriana Surleva, Catalina Ionica Ciobanu, Olga Pintilie, Carmen Iacoban, Gabi Drochioiu
Summary: This study identifies a source of heavy metal pollution in the Tarnia-Ostra area, Suceava County, Romania, and analyzes it using both chemical and biological techniques. The high concentrations of heavy metals found in this region may pose a high risk to the environment and public health through the food chain. The study also demonstrates that wheat germination tests can be a reliable and inexpensive biological method to prove the harmful effect of heavy metals and arsenic on plants.
ENVIRONMENTAL FORENSICS
(2023)
Article
Chemistry, Multidisciplinary
Cosmin Stefan Mocanu, Brindusa Alina Petre, Laura Darie-Ion, Gabi Drochioiu, Marius Niculaua, Iuliana Stoica, Mihaela Homocianu, Loredana Elena Nita, Vasile Robert Gradinaru
Summary: In this study, a new amidated peptide FRS based on human collagen sequence was synthesized and characterized. The self-assembly behaviors of FRS were investigated and optimal conditions were determined. AFM studies revealed the morphology of FRS and theoretical analysis showed its ability to form bundle-type association. This research has significant implications for further applications and design of FRS peptide.
Article
Chemistry, Multidisciplinary
Daniel Tabian, Diana Bulgaru Iliescu, Madalina Maria Diac, Mihaela Badea, Sebastian Ionut Toma, Gabi Drochioiu
Summary: An original kinetic spectrophotometric procedure was developed for the determination of hydrogen cyanide (HCN) in the whole blood of fire victims. The method proved to be accurate, sensitive, and selective, and has been successfully applied to the analysis of blood samples from several fire victims.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Medicinal
Ancuta-Veronica Lupaescu, Cosmin Stefan Mocanu, Gabi Drochioiu, Catalina-Ionica Ciobanu
Summary: Aggregation of amyloid-beta peptides is a key feature of Alzheimer's disease, and the deficiency of activity-dependent neuroprotective protein (ADNP) in AD has been associated with cognitive impairment. The 8-amino-acid peptide NAP, derived from ADNP, has shown potential in enhancing cognitive function. Zinc ions are known to promote A beta aggregation, and this study investigated the binding of zinc ions to NAP peptides using mass spectrometry and nuclear magnetic resonance.
Article
Biochemistry & Molecular Biology
Cosmin Stefan Mocanu, Marius Niculaua, Gheorghita Zbancioc, Violeta Mangalagiu, Gabi Drochioiu
Summary: This study explored peptide-based drugs with the potential to disrupt beta-sheet structures of amyloid-beta peptides in senile plaques, identifying peptides with fibril formation interference capability and good biocompatibility. The research highlighted the promising pharmacological properties of certain peptide conjugates and the lack of peptide fragmentation under protease action, suggesting potential therapeutic implications for Alzheimer's disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Cosmin Stefan Mocanu, Laura Darie-Ion, Brindusa Alina Petre, Vasile Robert Gradinaru, Gabi Drochioiu
Summary: Given the current context of the SARS-CoV-19 pandemic, hyperpyrexia and increased intracranial pressure may interfere with Ap peptide aggregation in the brains of Alzheimer's disease patients. Our study suggests that elevated temperature and increased intracranial pressure exacerbate the effect of peptide aggregation, potentially contributing to the formation of senile plaques in Alzheimer's disease brains.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Milazim Tahirukaj, Andriana Surleva, Petrica Vizureanu, Blerim Olluri, Andrei Victor Sandu
Summary: Gunshot residue (GSR) examination using SEM/EDS is a valuable tool in forensic studies. This study explored the relationship between the number of GSR particles identified by SEM/EDS and factors such as time, gun caliber, number of shots, and weather conditions. The results showed that GSR particles could be identified within five to seven hours after shooting, depending on the weapon and number of shots.
APPLIED SCIENCES-BASEL
(2022)
Article
Pharmacology & Pharmacy
Stefania-Claudia Jitaru, Andrei Neamtu, Gabi Drochioiu, Laura Darie-Ion, Iuliana Stoica, Brindusa-Alina Petre, Vasile-Robert Gradinaru
Summary: Peptides and their related compounds have the ability to form various nanostructures in response to stimuli, such as pH, temperature, and ionic strength. In this study, a pentapeptide derived from lysozyme was synthesized and characterized for its fibrillar structures. The peptide was synthesized using solid phase peptide synthesis and its properties were confirmed using spectroscopy and microscopy. The obtained fibrils show potential for medical and cosmetic applications.
Correction
Biochemistry & Molecular Biology
Cosmin Stefan Mocanu, Gabi Drochioiu
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2023)
Article
Chemistry, Analytical
Lyudmila Angelova, Nezabravka Genova, Gergina Pencheva, Yasena Statkova, Violeta Yotova, Andriana Surleva
Summary: This study presents a method using the molybdenum blue reaction for detecting the phosphorus content in soil analysis. The optimal conditions and parameters were determined through experiments. The study found that the inhomogeneity of soil samples and the repeatability of the extraction process were the main factors affecting the measurement uncertainty.
METHODS AND OBJECTS OF CHEMICAL ANALYSIS
(2022)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
