Article
Engineering, Chemical
Liping Luan, Bentian Tang, Yongfeng Liu, Aili Wang, Beibei Zhang, Wenlong Xu, Yuzhong Niu
Summary: This study developed sulfur-functionalized PAMAM dendrimer/magnetic Fe3O4 hybrid materials for efficient capturing of Hg(II) and Ag(I) from water solution. The hybrid materials exhibited good adsorption selectivity and could be regenerated for practical reuse.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
V. P. Kothavale, A. Sharma, R. P. Dhavale, V. D. Chavan, S. R. Shingte, O. Selyshchev, T. D. Dongale, H. H. Park, D. R. T. Zahn, G. Salvan, P. B. Patil
Summary: A magnetic nanoadsorbent based on PAMAM modification was developed for the simultaneous removal of coexisting heavy metal ions from water. The nanoadsorbent exhibited lower adsorption capacity for Pb(II), Ni(II), and Cd(II) in the ternary system, but higher adsorption capacity in the single systems. The adsorption kinetics followed the Langmuir model, while the isotherm followed the pseudo-second-order model.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Chemistry, Physical
Soheyla Karimi, Hassan Namazi
Summary: The study successfully fabricated a triazine dendrimer-functionalized graphene oxide nanocarrier for drug delivery systems with potential applications in cancer treatment. The results showed that the nanocarrier exhibited pH-responsive drug release behavior, excellent biocompatibility, and higher apoptotic effects on breast cancer cells.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Analytical
Fatemeh Hajizadeh, Amirhassan Amiri, Behrooz Maleki, Farrokhzad Mohammadi Zonoz
Summary: In this study, silica-coated magnetic nanoparticles functionalized with second-generation polyamidoamine dendrimer were synthesized and used for the magnetic solid-phase extraction of estradiol valerate from biological samples. The nanocomposite demonstrated good performance and exhibited a wide linear dynamic range and a low limit of detection. The estradiol valerate was successfully extracted from human plasma samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Analytical
Yin Dai, Wei Jiang, Yani Zheng, Pei He, Ruizhi Zhu, Jianwen Fei, Wei Xu, Chunbo Liu, Junli Hong
Summary: In this study, a selective method for the determination of myosmine was developed using molecularly imprinted polymers based on Fe3O4@SiO2 and PAMAM dendrimers. The MIPs showed excellent application prospects for the sensitive determination of trace myosmine in tobacco products with advantages of simple preparation and remarkable selectivity.
Article
Chemistry, Multidisciplinary
Max E. Distler, Kaitlin M. Landy, Kyle J. Gibson, Byeongdu Lee, Steven Weigand, Chad A. Mirkin
Summary: In this study, novel DNA dendrimers were synthesized and characterized, which can break the symmetry in colloidal crystals and enable directional interactions. By modulating the shape anisotropy of the DNA dendrimers, the distribution of nanoparticles within the crystals can be precisely controlled.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Applied
Fatemeh Farahbakhsh, Esmaeil Heydari-Bafrooei, Mehdi Ahmadi, Seyedeh Hoda Hekmatara, Mohammad Sabet
Summary: The research utilized anti-BPA aptamer functionalized gold electrode and magnetic Fe3O4/Au nanoparticles for the detection and analysis of BPA, successfully measuring the content of BPA in water, milk, juice samples, as well as the migration of BPA from different commercial plastic products.
Article
Pharmacology & Pharmacy
Londiwe Simphiwe Mbatha, Fiona Maiyo, Aliscia Daniels, Moganavelli Singh
Summary: Messenger RNA (mRNA) has been overlooked for gene therapy due to its instability, but recent studies have shown its advantages over DNA in cancer immunotherapy and vaccine development. This study successfully formulated folic-acid-(FA)-modified, poly-amidoamine-generation-5 (PAMAM G5D)-grafted gold nanoparticles (AuNPs) and demonstrated higher transgene expression in FA receptor-overexpressing cells, highlighting the importance of AuNP delivery system.
Article
Chemistry, Multidisciplinary
Yalin Wu, Huahua Bai, Qingxiang Zhou, Shuangying Li, Yayang Tong, Jinghan Guo, Boyao Zhou, Zhi Li, Yali Zhan, Menghua Liu, Yanhui Li, Tongxu Qu
Summary: A new magnetic nanomaterial with good adsorption capacity for Sudan dyes was synthesized in this study. It showed excellent sensitivity and precision, making it suitable for enrichment of trace environment pollutants in aqueous samples. The method based on this nanomaterial could be a robust and reliable alternative tool for routine monitoring of such pollutants.
FRONTIERS IN CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Fatemeh Banisheykholeslami, Morteza Hosseini, Ghasem Najafpour Darzi
Summary: PAMAM grafted chitosan as a biocompatible adsorbent showed high removal efficiency for two dyes, with endothermic and exothermic adsorption processes confirmed. Results from thermodynamics and kinetics studies supported the experimental data, demonstrating the superior potential of CS-PAMAM G2 for dye removal from aqueous phase.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Magdalena Szota, Pawel Wolski, Cristina Carucci, Flaminia Cesare Marincola, Jacek Gurgul, Tomasz Panczyk, Andrea Salis, Barbara Jachimska
Summary: This study investigates the effect of the protonation degree of G4PAMAM dendrimer and the anticancer drug 5-fluorouracil (5FU) on the efficiency of complex formation. The most favorable conditions for constructing the G4PAMAM-5FU complex are a low degree of protonation of the dendrimer molecule with the drug simultaneously present in a deprotonated form. The formation of the stable complex is confirmed by fluorine components in the XPS spectra.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Devaraj Manoj, Lalitha Gnanasekaran, Saravanan Rajendran, A. A. Jalil, Mohammad Nahid Siddiqui, F. Gracia, Matias Soto-Moscoso
Summary: The subject of water contamination and its impact on society and humans has been a topic of discussion for several decades. Phenolic compounds are widely found in water sources and it is crucial to determine their toxicity in natural and drinking water due to their harmful effects on humans. This study focuses on the development of an effective electrochemical sensor using a mesoporous structure of Fe3O4-TiO2 decorated on a glassy carbon electrode to detect catechol. The resulting Fe3O4-TiO2 based nanocomposite exhibited a mesoporous structure with highly active magnetite nanoparticles, showing a significant increase in the electrochemical response compared to pure TiO2.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Nurdan Kurnaz Yetim, Fatma Kursun Baysak, Mumin Mehmet Koc, Dilek Nartop
Summary: The study investigated the utilization of Fe3O4@G2/Au/Bi2O3 nanocomposites for multimodal imaging applications. The physical and chemical structures of the nanocomposites were characterized using SEM, TEM, EDX, FTIR, and VSM. The results showed that the nanocomposites exhibit superparamagnetic properties suitable for MRI and magnetic hyperthermia applications, and their X-ray imaging and CT imaging properties were also confirmed.
JOURNAL OF NANOSTRUCTURE IN CHEMISTRY
(2021)
Article
Biophysics
Haobo Zhang, Weihan Wang, Lilong Wei, Dezhen Wu, Jue Cheng, Feng Gao
Summary: The research successfully grafted PAMAM onto the surface of PET, controlling the graft density and surface roughness by adjusting UV irradiation time and PAMAM generation. The decorated PET demonstrated antibacterial ability against S. aureus and E. coli, with higher generation dendrimers showing increased lethality. The un-selectivity and instantaneity of carbene chemistry suggest potential for extending this grafting strategy to other organic substances.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Correction
Chemistry, Physical
Handriela Hoff de Oliveira Sobrinho, Renato Eising, Ernesto Osvaldo Wrasse
Summary: In this paper published in Molecular Systems Design & Engineering, Handriela Hoff de Oliveira Sobrinho et al. corrected the adsorption behavior of doxorubicin on a PAMAM dendrimer using ab initio calculations.
MOLECULAR SYSTEMS DESIGN & ENGINEERING
(2023)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.