期刊
FOOD CHEMISTRY
卷 129, 期 2, 页码 272-278出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2011.04.040
关键词
Rosa hybrida; Petals; Anthocyanin; HPLC-DAD-ESI/MS; Antioxidant; Anticancer; Antiallergic
The objectives of the present study were to investigate anthocyanin profiles and their biological properties, including antioxidant, anticancer, and antiallergic, from the red petals of Korean edible rose (Rosa hybrida cv. Noblered). The acidic methanol extract of this species showed potent biological activities at a concentration of 50 mu g/mL. Its anthocyanins were characterised as cyanidin 3,5-di-O-glucoside and pelargonidin 3,5-di-O-glucoside using reversed-phase C-18 column chromatography, NMR spectroscopy, and HPLC-DAD-ESI/MS analysis. Cyanidin 3,5-di-O-glucoside was the predominant constituent (375 mg/100 g), representing about 85% of total content. Cyanidin 3,5-di-O-glucoside exhibited good scavenging activity against DPPH radical with IC50 value of 55.2 mu g/mL; pelargonidin 3,5-di-O-glucoside showed potent anticancer effects against LNCap (human prostate cell line), ACHN (human renal cell line) and MOLT-4F (human leukaemia cell line) cell cultures, with IC50 values of 6.43, 18.3, and 6.78 mu g/mL, respectively. Antiallergic activities were only moderate. (C) 2011 Elsevier Ltd. All rights reserved.
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