Review
Biochemistry & Molecular Biology
Alejandra Vanessa Lopez-Corona, Illeen Valencia-Espinosa, Fabio Antonio Gonzalez-Sanchez, Angelica Lizeth Sanchez-Lopez, Luis Eduardo Garcia-Amezquita, Rebeca Garcia-Varela
Summary: Raspberries contain a wide range of phenolic compounds that have antioxidant and anti-inflammatory activities, which may be beneficial for the treatment of chronic degenerative diseases and cancer.
Review
Biochemistry & Molecular Biology
Jaeeun Lee, Min-Hyun Kim, Hyeyoung Kim
Summary: A moderate amount of ROS plays an important role in cell signaling and immune response, while excessive production can lead to inflammation and pathological conditions. The gastrointestinal mucosa is continuously exposed to ROS, increasing the risk of GI disorders. AST, a compound with antioxidant and anti-inflammatory properties, has shown protective effects against GI diseases through various mechanisms, including ROS neutralization, enhancement of antioxidant enzyme activity, and suppression of inflammation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Medicine, Research & Experimental
Sepideh Bastani, Vahid Vahedian, Mohsen Rashidi, Amirabbas Mir, Sepideh Mirzaei, Iraj Alipourfard, Farhad Pouremamali, Hamidreza Nejabati, Jamileh Kadkhoda, Nazila Fathi Maroufi, Maryam Akbarzadeh
Summary: This review article provides a comprehensive overview of the antioxidant and anti-inflammatory effects of Crocin in various diseases and tissues. It highlights the potential of Crocin in the treatment of cardiovascular disease, cancer, diabetes, and kidney disease, as well as its role in the COVID-19 pandemic.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Environmental Sciences
Yi-Hui Su, Jia-Shuan Wu, Yan-Zhen Dai, Yng-Tay Chen, Yan-Xiu Lin, Yew-Min Tzeng, Jiunn-Wang Liao
Summary: This study evaluated the antioxidant activity, genotoxicity, and oral toxicity of Antrocin. The results showed that Antrocin has strong antioxidant activity and is not genotoxic. In addition, it did not produce any toxic effects in rats at a dose of 37.5 mg/kg. Therefore, Antrocin can be considered as a reference dose for therapeutic agents in humans.
Article
Food Science & Technology
Li-You Chen, Hsin-Lin Cheng, Chih-Kai Liao, Yu-Hsiang Kuan, Tang-Jun Liang, To-Jung Tseng, Hsing-Chun Lin
Summary: The aim of this study is to explore the potential anti-oxidant and anti-inflammatory mechanisms of luteolin in the treatment of diabetic nephropathy. Luteolin significantly reduced blood glucose and BUN levels in diabetic rats and increased serum sodium and chloride levels. Moreover, luteolin inhibited the activation of PI3K/Akt signaling pathway and the expressions of its downstream apoptosis-related proteins.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Food Science & Technology
Urszula Szymanowska, Monika Karas, Urszula Zlotek, Anna Jakubczyk
Summary: The study found that adding 100% raspberry juice to wafers is most beneficial for increasing the antioxidant activity of the wafers. The content of total phenolic compounds, flavonoids, phenolic acids, and anthocyanins in the wafers increased with the increasing amount of raspberry juice added. Additionally, simulated digestion increased the content of phenolic compounds and antioxidant activity of the wafers.
Article
Oncology
Nelson Sham, Chenglu Qin, Ziwen Zhu, Chase G. Redington, Huaping Xiao, Qian Bai, Mark R. Wakefield, Leon Kou, Yujiang Fang
Summary: The study showed that raspberry extract has anticancer activity against cervical cancer HeLa cells by up-regulating anti-proliferative molecule P53 and pro-apoptotic molecule FAS.
ANTICANCER RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Weiling Lu, Changchang Kong, Shijunyin Cheng, Xiaodong Xu, Jianfa Zhang
Summary: The study shows that riclin can protect the skin from UVB-induced damage, with antioxidant and anti-inflammatory effects. Riclin increases collagen expression and inhibits oxidation and melanin synthesis. In vivo experiments on mice demonstrate that riclin effectively reduces UVB-induced skin damage and suppresses inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Changxi Qi, Liping Li, Guodong Cheng, Bin Xiao, Yuxiao Xing, Xiaona Zhao, Jianzhu Liu
Summary: Platycodon grandiflorus polysaccharides (PGPS(t)) exhibit hepatoprotective effects in mice with acute liver injury induced by LPS/D-GalN, alleviating oxidative stress, reducing inflammatory cytokines, and enhancing the expression of anti-apoptotic proteins.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2021)
Article
Biochemistry & Molecular Biology
Lukasz Swiatek, Elwira Sieniawska, Kouadio Ibrahime Sinan, Gokhan Zengin, Anastazja Boguszewska, Benita Hryc, Kouadio Bene, Malgorzata Polz-Dacewicz, Stefano Dall'Acqua
Summary: This study investigated the chemical profiles and biological properties of Justicia secunda extracts obtained using different solvents. Over 50 compounds, including flavonoids, phenolic acids, and alkaloids, were identified using LC-MS. The methanol and water extracts showed higher phenolic and flavonoid contents and stronger antioxidant abilities. The dichloromethane and ethyl acetate extracts exhibited greater activity against alpha-amylase and alpha-glucosidase. The aqueous extracts demonstrated selective anticancer properties and the methanolic extract decreased the infectious titer and viral load of human herpesvirus type-1. Overall, J. secunda could be used as a multifunctional bioactive raw material for managing diseases related to oxidative stress.
Article
Food Science & Technology
Xiong Gao, Xiaorong Lin, Chi-Tang Ho, Yuanyuan Zhang, Bin Li, Zhongzheng Chen
Summary: This study compared the chemical composition and anti-inflammatory activity of black cocoa tea and Yunnan Daye tea. Results showed that black cocoa tea had higher levels of gallic acid, total catechins, and total polyphenols, and exhibited stronger anti-inflammatory activity.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Shuai Zong, Helin Wang, Jinglei Li, Jun Liu, Changhai Jin
Summary: Zhuke-Hulu tea showed significant anti-oxidant activity by enhancing endogenous anti-oxidant defense system and Nrf2 nuclear translocation, and exhibited anti-inflammatory efficiency by down-regulating protein levels of iNOS and COX-2 as well as production of pro-inflammatory cytokines. Additionally, it alleviated intestinal inflammation by reducing pro-inflammatory cytokines levels, inhibiting inflammatory cell infiltration, and modulating gut microbiota.
Article
Materials Science, Ceramics
Anbang Chen, Yunhe Fu, Yuandong Mu, Qingfeng Wang, Chris Parr, Guotian Ye
Summary: The addition of andalusite aggregate can enhance the oxidation resistance of Al2O3-SiC-C castable and reduce the dosage of antioxidant. The liquid glass produced by the transformation of andalusite can block oxygen entry, contribute to a denser structure, and improve the oxidation resistance of the castable.
CERAMICS INTERNATIONAL
(2021)
Article
Food Science & Technology
Florence Malongane, Lyndy Joy McGaw, Oyinlola Oluwunmi Olaokun, Fhatuwani Nixwell Mudau
Summary: South Africa is known for its various herbal teas with antioxidant, anti-inflammatory and anti-diabetic properties. This study investigated the antioxidant activity, anti-inflammatory effects, and anti-diabetic properties of selected tea blends. The results showed that special tea and its blend with bush tea exhibited potent antioxidant and anti-inflammatory activity, and blending increased the antioxidant activity. All the tea samples also showed anti-diabetic effects, although less potent than insulin. The findings support the use of blended herbal teas and suggest further research on the anti-inflammatory effects of special tea.
Article
Engineering, Biomedical
Keke Wu, Meimei Fu, Yitao Zhao, Ethan Gerhard, Yue Li, Jian Yang, Jinshan Guo
Summary: This study developed a multifunctional bioadhesive made from the natural polyphenolic compound tannic acid, which possesses antioxidant, anti-inflammatory, and antimicrobial properties. The bioadhesive showed favorable biocompatibility and mechanical strength, and it promoted wound closure and scarless healing.
BIOACTIVE MATERIALS
(2023)
Article
Food Science & Technology
Hana Jung, Hee Jae Lee, Hyunnho Cho, Kiuk Lee, Ho-Kyung Kwak, Keum Taek Hwang
FOOD SCIENCE AND BIOTECHNOLOGY
(2015)
Article
Biochemistry & Molecular Biology
Hana Jung, Hee Jae Lee, Hyunnho Cho, Keum Taek Hwang
JOURNAL OF FOOD BIOCHEMISTRY
(2015)
Article
Biochemistry & Molecular Biology
Hee Jae Lee, Hana Jung, Hyunnho Cho, Keum Taek Hwang
JOURNAL OF FOOD BIOCHEMISTRY
(2015)
Article
Food Science & Technology
Hyun Ju Won, Hae Chang Yi, Hana Jung, Hyunnho Cho, Bomee Lee, Keum Taek Hwang
JOURNAL OF FOOD PROCESSING AND PRESERVATION
(2015)
Article
Biochemistry & Molecular Biology
Hyunnho Cho, Hana Jung, Heejae Lee, Hae Chang Yi, Ho-kyung Kwak, Keum Taek Hwang
Article
Food Science & Technology
Hyunnho Cho, Hana Jung, HeeJae Lee, Ho-Kyung Kwak, Keum Taek Hwang
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Hee Jae Lee, Hana Jung, Hyunnho Cho, Kiuk Lee, Ho-Kyung Kwak, Keum Taek Hwang
Article
Nutrition & Dietetics
Hana Jung, C. -Y. Oliver Chen, Jeffrey B. Blumberg, Ho-Kyung Kwak
EUROPEAN JOURNAL OF NUTRITION
(2018)
Article
Biochemistry & Molecular Biology
Hee Jae Lee, Hana Jung, Hyunnho Cho, Kiuk Lee, Keum Taek Hwang
Article
Food Science & Technology
Hana Jung, Ho-Kyung Kwak, Keum Taek Hwang
FOOD SCIENCE AND BIOTECHNOLOGY
(2014)
Article
Biochemistry & Molecular Biology
Miyoung Park, Hyunnho Cho, Hana Jung, Heejae Lee, Keum Taek Hwang
JOURNAL OF FOOD BIOCHEMISTRY
(2014)
Article
Biochemistry & Molecular Biology
Sun Young Park, Hana Jung, Zhaoyan Lin, Keum Taek Hwang, Ho-Kyung Kwak
Summary: The study found that black raspberry supplementation had positive effects against inflammation and endothelial dysfunction induced by high-fat/high-fructose diet. Rats supplemented with black raspberry had higher HDL-cholesterol and lower triglycerides, along with decreased expression of inflammatory markers in liver and aorta tissues.
JOURNAL OF FOOD BIOCHEMISTRY
(2021)
Article
Health Care Sciences & Services
Young Mi Kim, Jin Dong Kim, Hana Jung
Summary: The study showed that the controlled group had significantly higher total amount of moderate-intensity activities compared to the uncontrolled group. Meanwhile, the uncontrolled group had significantly higher total energy, fat, and other nutrient intakes than the controlled group. Furthermore, intakes of certain nutrients were significantly lower in the uncontrolled group, indicating the importance of proper nutrition and physical activity for effective blood glucose management in diabetic patients undergoing therapy.
INQUIRY-THE JOURNAL OF HEALTH CARE ORGANIZATION PROVISION AND FINANCING
(2021)
Meeting Abstract
Biochemistry & Molecular Biology
Sun Young Park, Hana Jung, Keum Taek Hwang, Ho-Kyung Kwak
Meeting Abstract
Biochemistry & Molecular Biology
Kiuk Lee, Hana Jung, Keum Taek Hwang, Ho-Kyung Kwak
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.