Article
Chemistry, Applied
Khalil Ahmad, Jawad Manzur, Muhammad Tahir, Rabia Hussain, Mahmood Khan, Abdul Wadood, Egemen Avcu, Muhammad Atiq Ur Rehman
Summary: In this study, zein coatings containing cloves were developed on stainless steel substrates using electrophoretic deposition. The coatings exhibited excellent antibacterial activity, drug release capability, surface properties, corrosion resistance, and adhesion. These zein/cloves coatings have potential applications in orthopedics as they possess antimicrobial effects and can provide targeted drug delivery.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Endocrinology & Metabolism
M. C. Thomas
Summary: Type 2 diabetes and its comorbidities, including cardiovascular disease, heart failure, chronic kidney disease, fatty liver disease, and eye and foot disease, are interrelated and caused by a failure to efficiently manage excessive energy. These conditions worsen each other through shared pathogenesis and subsequent dysfunction. CARAMEL disease, a combination of cardiac, renal, adipo-metabolic, eye, and liver disease, is commonly found in patients with type 2 diabetes. Recent changes in diabetes guidelines emphasize the identification and aggressive management of high-risk individuals.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2022)
Article
Optics
Sara Ferrer-Altabas, Larry Thibos, Vicente Mico
Summary: This study presents a variable and continuous astigmatic power optical device based on a modified Stokes lens. By combining two sphero-cylindrical lenses and a fixed pure astigmatic lens, this device improves the expansion capability of the astigmatic range without compromising the dioptric power step resolution.
Review
Endocrinology & Metabolism
Zhen Zhang, Jianyun Sun, Meng Guo, Xuemin Yuan
Summary: Organ transplantation is an effective treatment for end-stage organ failure, but post transplantation diabetes mellitus (PTDM) is a severe complication that affects the survival of recipients. However, PTDM is often overlooked or poorly managed in its early stage. This article provides an overview of the incidence, pathogenesis, and risk factors for PTDM, aiming to improve the quality of life of recipients.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Optics
Yannanqi Li, Tao Zhan, Zhiyong Yang, Chi Xu, Patrick L. LiKamWa, Kun Li, Shin-Tson Wu
Summary: The designed planar and broadband cholesteric liquid crystal (CLC) lens hybridized with a refractive lens forms a catadioptric pancake lens for virtual reality (VR) displays. The chromatic aberration of the assembled pancake lens is dramatically suppressed due to the opposite optical dispersion behaviors, showing great potential for next-generation VR displays.
Article
Biochemical Research Methods
Blazej Grodner
Summary: A total non-aqueous capillary electrophoresis method was developed for the quantification of eugenol in cloves and dental preparations. The method showed rapid detection time, good linearity, low detection limit, and high extraction yield.
Article
Engineering, Chemical
David Necas, Vlastimil Kulisek, Petr Stepan, Frantisek Ondreas, Pavel Cipek, Gloria Huerta-Angeles, Martin Vrbka
Summary: This paper investigates the cause of eye irritation, dry eye syndrome, in contact lens users, and focuses on the impact of different solution components on the contact behavior between the lens and the eyelid through measuring the friction coefficient and observing lubricating film formation. The results indicate that the lens material, mucin, and buffer type play a decisive role in contact behavior. The appropriate eye drop ingredient is suggested based on the score of biotribological performance for Acuvue Oasys and Biofinity contact lenses.
Article
Engineering, Electrical & Electronic
Loic Massin, Fabrice Seguin, Vincent Nourrit, Emmanuel Daniel, Jean-Louis de Bougrenet de la Tocnaye, Cyril Lahuec
Summary: This paper introduces a new approach for gaze tracking using a smart contact lens without a camera, which calculates the gaze direction by computing the barycenter from photocurrents. Experimental results show that the proposed system is 2.5 times more accurate than current camera-based eye-trackers.
IEEE SENSORS JOURNAL
(2021)
Article
Immunology
Mengqin Wang, Ji Zhang, Jiasi Zhang, Kailun Sun, Qingwen Li, Baicheng Kuang, M. M. Zhiheng Wang, Shuaiheng Hou, Nianqiao Gong
Summary: The study demonstrates that methyl eugenol can alleviate liver ischemia reperfusion injury (LIRI) induced damage, inflammation, and apoptosis, while also reducing liver cell injury caused by hypoxia-reoxygenation. This protective effect may be related to the activation of the PI3K/Akt signaling pathway.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Cell Biology
Matthieu Duot, Roselyne Viel, Justine Viet, Catherine Le Goff-Gaillard, Luc Paillard, Salil A. Lachke, Carole Gautier-Courteille, David Reboutier
Summary: This study successfully generated lens organoids that mimic the properties and organization of the lens tissue, providing a new research tool for studying lens biology and cataracts, as well as for drug screening.
Article
Fisheries
Hongbiao Dong, Xiangbing Zeng, Wenhao Wang, Yafei Duan, Jian Chen, Jiasong Zhang
Summary: In this study, the protective efficiency of Teprenone against the damage caused by two types of anesthetics, MS-222 and eugenol, in the liver and gills of L. maculatus was evaluated. The results showed that dietary Teprenone reduced apoptosis and induced the production of HSP70, thus alleviating the anesthetic damage in L. maculatus.
Article
Ophthalmology
Kehao Wang, Irene Vorontsova, Masato Hoshino, Kentaro Uesugi, Naoto Yagi, James Ewbank Hall, Thomas Friedrich Schilling, Barbara Krystyna Pierscionek
Summary: This study uses CRISPR/Cas9 gene editing to generate loss-of-function deletions of aqp0a and/or aqp0b in zebrafish, and measures lenses of mutant fish at different developmental stages using x-ray Talbot interferometry. The results suggest that Aqp0a and Aqp0b have region-specific functions in lens development, with Aqp0a regulating centralization of the plateau region peripherally and either Aqp0a or Aqp0b required for the formation of the plateau region in the lens center.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Medicine, General & Internal
Fu-Shun Yen, Ming-Chih Hou, Jia-Sin Liu, Chih-Cheng Hsu, Chii-Min Hwu
Summary: This study compared the risk of severe hypoglycemia between patients with type 2 diabetes, with and without compensated liver cirrhosis. It found that patients with compensated cirrhosis had a higher risk of mortality and severe hypoglycemia.
FRONTIERS IN MEDICINE
(2023)
Article
Medicine, Research & Experimental
Moustafa Fathy, Rania Abdel-latif, Yasmeen M. Abdelgwad, Othman Ali Othman, Abdel-Razik H. Abdel-Razik, Thomas Dandekar, Eman M. Othman
Summary: The study showed that eugenol has a potential protective effect against CCl4-induced chronic kidney damage in an experimental model, mainly through its antioxidant, anti-inflammatory, and anti-fibrotic activities.
Article
Nutrition & Dietetics
Yuge Jiang, Chuanxing Feng, Yonghui Shi, Xingran Kou, Guowei Le
Summary: Eugenol has been found to have potential protective effects on muscle function and prevention of muscle inflammation. It can lower blood glucose and insulin resistance, reduce muscle inflammation induced by a high-fat diet and streptozocin injection, and prevent muscle weakness and atrophy. This may be explained by the increased translocation of GLUT4 and phosphorylation of AMPK in skeletal muscle, resulting in enhanced glucose uptake.
FRONTIERS IN NUTRITION
(2022)
Article
Biology
M. S. Khan, S. M. Ibrahim, A. A. Adamu, M. B. A. Rahman, M. Z. Abu Bakar, M. M. Noordin, M. Y. Loqman
Article
Infectious Diseases
Jamilu Abubakar Bala, Krishnan Nair Balakrishnan, Faez Firdaus Abdullah Jesse, Ashwaq Ahmed Abdullah, Muhammad Syaafii bin Noorzahari, Mohd Termizi Ghazali, Ramlan Bin Mohamed, Abd Wahid Haron, Mustapha Mohamed Noordin, Mohd Lila Mohd-Azmi
INFECTION GENETICS AND EVOLUTION
(2020)
Article
Agriculture, Dairy & Animal Science
Shakirin Hanim Faridah, Yong Meng Goh, Mohamed Mustapha Noordin, Juan Boo Liang
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES
(2020)
Article
Veterinary Sciences
Trang Hong Pham, Mohd Azmi Mohd Lila, Nor Yasmin Abd Rahaman, Huong Lan Thi Lai, Lan Thi Nguyen, Khien Van Do, Mustapha M. Noordin
BMC VETERINARY RESEARCH
(2020)
Article
Oncology
Abdullahi Aliyu, Mohd Rosly Shaari, Nurul Syahirah Ahmad Sayuti, Mohd Farhan Hanif Reduan, Shanmugavelu Sithambaram, Mustapha Mohamed Noordin, Khozirah Shaari, Hazilawati Hamzah
Article
Biochemistry & Molecular Biology
Abdullahi Aliyu, Mohd Rosly Shaari, Nurul Syahirah Ahmad Sayuti, Mohd Farhan Hanif Reduan, Shanmugavelu Sithambaram, Mustapha Mohamed Noordin, Khozirah Shaari, Hazilawati Hamzah
Article
Agriculture, Dairy & Animal Science
Ali Merzza Humam, Teck Chwen Loh, Hooi Ling Foo, Wan Ibrahim Izuddin, Elmutaz Atta Awad, Zulkifli Idrus, Anjas Asmara Samsudin, Noordin Mohamed Mustapha
Article
Food Science & Technology
Mazween Mohamad Mazlan, Rosnita A. Talib, Nyuk Ling Chin, Radhiah Shukri, Farah Saleena Taip, Mohd Zuhair Mohd Nor, Norazlin Abdullah
Article
Pharmacology & Pharmacy
Nazmun Nahar, Suhaila Mohamed, Noordin Mohamed Mustapha, SengFong Lau, Nur Iliyani Mohd Ishak, Norshahira Solehah Umran
Summary: The study demonstrated that metformin significantly attenuated hyperglycemia-induced ocular abnormalities by regulating certain proteins and oxidative stress levels. These findings suggest that metformin may have potential therapeutic effects in improving diabetic ocular complications.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
(2021)
Article
Multidisciplinary Sciences
Azwan Hamdan, Mohd Qayyum Ab Latip, Hasliza Abu Hassim, Mohd Hezmee Mohd Noor, Tengku Rinalfi Putra Tengku Azizan, Noordin Mohamed Mustapha, Hafandi Ahmad
SCIENTIFIC REPORTS
(2020)
Article
Veterinary Sciences
Trang Hong Pham, Nor Yasmin Abdul Rahaman, Mohd Azmi Mohd Lila, Huong Lan Thi Lai, Lan Thi Nguyen, Giap Van Nguyen, Bo Xuan Ha, Hieu Nguyen, Hanh Duc Vu, Mustapha M. Noordin
Summary: After a decade of silence, an outbreak of goat pox re-emerged in North Vietnam, affecting more than 1800 goats with a mortality rate of 6.5%, causing significant economic losses to the developing goat industry of Vietnam. A phylogenetic study revealed the genetic relatedness of the Vietnamese strain to goat pox strains in China, India, and Pakistan, suggesting a common origin in South China.
BMC VETERINARY RESEARCH
(2021)
Article
Chemistry, Applied
Radhiah Shukri, Sajid Alavi, Hulya Dogan, Yong-Cheng Shi
Summary: This study investigated the extrusion of cross-linked waxy maize starches with different cross-linking levels as a secondary ingredient in extruded oat flour formulations. Low cross-linking levels increased void fraction and reduced breaking strength, while higher levels restricted swelling of starch granules and increased resistant starch content. Varying the level of cross-linking offers an alternative way to manipulate the structural, textural, and nutritional properties of extrudates in snack and cereal applications.
CARBOHYDRATE POLYMERS
(2021)
Article
Pharmacology & Pharmacy
Nur Izzah Md Fadilah, Mohd Basyaruddin Abdul Rahman, Loqman Mohamad Yusof, Noordin Mohamed Mustapha, Haslina Ahmad
Summary: The study demonstrates the potential of a novel peptide Palmitoyl-GDPH in wound healing, showing faster healing and reduced scar formation. In experiments with SD rats, the Palmitoyl-GDPH treated group exhibited better healing outcomes, with stimulation of hair follicle growth and lower hemogram values compared to the control group.
Article
Virology
Krishnan Nair Balakrishnan, Ashwaq Ahmed Abdullah, Jamilu Abubakar Bala, Faez Firdaus Abdullah Jesse, Che Azurahanim Che Abdullah, Mustapha Mohamed Noordin, Mohd Lila Mohd-Azmi
Article
Toxicology
Farhan Hanif Reduan, Rosly Mohd Shaari, Nurul Syahirah Ahmad Sayuti, Noordin Mohamed Mustapha, Md Zuki Abu Bakar, Shanmugavelu Sithambaram, Hazilawati Hamzah
TOXICOLOGICAL RESEARCH
(2020)
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
