期刊
FOOD AND CHEMICAL TOXICOLOGY
卷 50, 期 8, 页码 2696-2702出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.fct.2012.05.028
关键词
Mercury; Selenium; Seafood; Bioaccessibility; Caco-2 cell; Molar ratio
资金
- Spanish Ministry of Science and Innovation [AGL2005-00619]
- Generalitat Valenciana [AE06106]
- BANCAJA-CSIC
This study evaluates Hg and Se concentrations and bioaccessibility (element solubilised after simulated gastrointestinal digestion) in 16 raw seafood species consumed in Spain. The concentrations varied greatly (Hg, 3.8-1621 ng/g wet weight, ww: Se, 84-1817 ng/g ww). Only one sample of swordfish exceeded the Hg limit permitted in Spain (1 mg/kg), and for this sample the Hg/Se molar ratio and Se Health Benefit Value food safety criteria also indicated the presence of a risk. Bioaccessibility of Hg (35-106%) and Se (17-125%) was very variable and the Hg/Se molar ratio in the bioaccessible fraction was less than one for all samples. Transport by Caco-2 cells, an intestinal epithelium model, was also evaluated from the swordfish bioaccessible fraction. Hg and Se transport from the food was less than 14%, and cell retention was much greater for Hg (49-69%) than Se (8-12%). (C) 2012 Elsevier Ltd. All rights reserved.
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