Article
Biochemical Research Methods
Natalia Barger, Ilan Oren, Ximing Li, Mouna Habib, Ramez Daniel
Summary: Early detection of blood in urine is crucial for the treatment of serious diseases, and the development of low-cost portable biosensors for this purpose is necessary. An ultrasensitive whole-cell bacterial biosensor was designed for heme detection in urine, showing promising results for hematuria detection.
ACS SYNTHETIC BIOLOGY
(2021)
Article
Biochemical Research Methods
Swati Mishra, Harshawardhan Wanare
Summary: This study demonstrated that the amount of bilirubin in newborns can be accurately measured using a few specific wavelengths. The researchers conducted a preliminary study using blood samples from 50 neonates and developed a hierarchical decision model to predict bilirubin levels.
JOURNAL OF BIOMEDICAL OPTICS
(2023)
Article
Environmental Sciences
Wei Sun, Cuihong Jin, Yinglong Bai, Ruixue Ma, Yuan Deng, Yuan Gao, Guowei Pan, Zuosen Yang, Lingjun Yan
Summary: Nano- and micro-plastic pollution is a global issue, and the absorption of these pollutants in the blood and their excretion through urine are controversial. This study found that both nano- and micro-plastics can enter the blood circulation through digestive and respiratory pathways, and there is a possibility of excretion through urine, although further evidence is needed.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Environmental
Amir Mirshafiee, Abbas Rezaee
Summary: This study introduced a laboratory-scale anaerobic treatment system for removing oil from synthetic wastewater using a biofilm-electrode reactor (BER). Results showed that the optimal conditions led to higher COD removal efficiency compared to general biological processes, and the biokinetic study supported the use of the modified Stover-Kincannon model for the removal reaction.
JOURNAL OF WATER PROCESS ENGINEERING
(2021)
Article
Food Science & Technology
Skyler A. Price, Mark A. Maddaloni, Brent L. Finley, Stephanie A. Thornton, Ken M. Unice
Summary: The U.S. FDA proposed lead action levels for baby and child food based on a daily dietary Pb reference value of 2.2 μg/day. Biokinetic models were compared to understand potential exposures to Pb in baby food. Soil and dust were found to be the primary contributors to infant blood lead levels, while food and water had a minor contribution.
Article
Nuclear Science & Technology
Laurent Desorgher, Nina Mosimann, Rolf Althaus, Christoph Wirz, Claude Bailat, Siria Medici, Francois Bochud
Summary: In this study, the Whole-body counters (WBC) were characterized and calibrated using Monte Carlo simulations and experimental validation. The efficiency of WBC was found to be dependent on the size of the individual, and calibration with phantoms of different sizes was recommended for better accuracy. It was also observed that WBC measurements may overestimate whole-body activity in the case of non-homogeneous distribution of radioisotopes in the body. Scanning the entire body with detectors or increasing the distance between detectors and phantom were suggested to reduce this bias.
RADIATION MEASUREMENTS
(2022)
Article
Water Resources
Dominika Heusinkveld, Monica D. Ramirez-Andreotta, Tania Rodriguez-Chavez, A. Eduardo Saez, Eric Betterton, Kyle Rine
Summary: Lead exposure is harmful to humans, with no safe levels in children. A study in Arizona found that indoor dust containing lead is the main contributor to childhood lead poisoning. Efforts to reduce lead exposure risk should focus on decontaminating outdoor soil and indoor dust.
EXPOSURE AND HEALTH
(2021)
Article
Biochemistry & Molecular Biology
Gang Zhao, Si-jin Liu, Xin-yu Gan, Jun-ru Li, Xiao-xue Wu, Si-yan Liu, Yi-si Jin, Ke-rang Zhang, Hong-mei Wu
Summary: The relationship between trace elements and neurological development is an emerging research focus. This case-control study investigated the differences in trace element concentrations in blood and urine between children with autism spectrum disorder (ASD) and typically developing peers. The study also examined the association between these trace elements and core behaviors of ASD. The results showed that certain trace elements were significantly higher in the blood of ASD cases compared to controls, and these concentrations were correlated with core behaviors of ASD.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Biodiversity Conservation
Kenneth T. Bogen, Joyce S. Tsuji, Michael D. Taylor, Andrew Taylor, Marina Patriarca
Summary: The study provides a new method for developing Worker-specific Biological Exposure Action Levels (BEALs) for urinary nickel exposure, which helps in evaluating workers' nickel exposure levels based on health-based criteria.
HUMAN AND ECOLOGICAL RISK ASSESSMENT
(2021)
Article
Biochemistry & Molecular Biology
Naima Younus, Amina Zuberi
Summary: Extrinsic factors in aquaculture feed manufacturing practices have a significant impact. This study evaluated the effects of different chemical forms and dosage levels of dietary cobalt on the growth performance, hematological, and immunological indices of Tor putitora fingerlings. The results showed significant effects of different chemical forms and dosage levels on the fish, with the Co-Met supplemented group at a dosage of 3 mg/kg diet showing the highest growth performance and improved hemato-immunological indices.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2022)
Article
Engineering, Biomedical
Hannah Varner, Gabriella P. Sugerman, Manuel K. Rausch, Tal Cohen
Summary: Measuring and understanding the mechanical properties of blood clots is important for disease progression and treatment effectiveness assessment. A recently developed technique called Volume Controlled Cavity Expansion (VCCE) is used to measure the local mechanical properties of soft materials in their natural environment. The results obtained through this technique are compared with theoretical models and existing data, providing reliable and repeatable results. The findings suggest the wider adoption of VCCE to improve the understanding of the mechanics of soft biological materials.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Medicine, General & Internal
Jan Karregat, Maike G. Sweegers, Franke A. Quee, Henriette H. Weekamp, Dorine W. Swinkels, Vera M. J. Novotny, Hans L. Zaaijer, Katja van den Hurk
Summary: This study aims to evaluate the impact of different iron supplementation protocols, in terms of dosage and frequency, on iron status and health effects. It will provide scientific evidence to guide the use of oral iron supplements in the recovery of whole blood donors with low ferritin levels, considering individual differences in treatment adherence and lifestyle.
Article
Engineering, Environmental
T. Reshma Mohan, M. S. Mohan Kumar, Lakshminarayana Rao
Summary: A hydrodynamic-biokinetic integrated model was developed to investigate the treatment efficiency of bioreactors. The model successfully optimized the treatment process and reduced TCOD and TN concentrations.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Sport Sciences
Jacob Bejder, Gozde Gurdeniz, Catalina Cuparencu, Frederikke Hall, Mikkel Gybel-Brask, Andreas Breenfeldt Andersen, Lars Ove Dragsted, Niels H. Secher, Par I. Johansson, Nikolai Baastrup Nordsborg
Summary: This study found that an untargeted urine metabolomics analysis can reveal the metabolic pattern of autologous blood transfusion, providing an effective detection method. The strongest model was obtained 2 hours after reinfusion, and combining only a few of the strongest metabolites selected by this model provided high sensitivity and specificity for detection.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Medicine, Legal
E. Dale Hart, Nichole D. Bynum, Amy Evans, Kenneth D. Swanson, Thomas A. Blake
Summary: A proficiency testing (PT) scheme was developed for laboratories engaged in bioanalytical testing for synthetic opioid compounds. The scheme involved two PT events each year for two years, with an expansion of participating laboratories in the second year. The PT samples were prepared using compounds from the Opioid Certified Reference Material Kit. The results showed improvements in drug detection between the PT events, highlighting the benefits of PT schemes in identifying and addressing deficiencies in laboratory systems.
FORENSIC SCIENCE INTERNATIONAL
(2023)
Article
Environmental Sciences
Jennifer Sahmel, Christy A. Barlow, Shannon Gaffney, Heather J. Avens, Amy K. Madl, John Henshaw, Ken Unice, David Galbraith, Gretchen DeRose, Richard J. Lee, Drew Van Orden, Matthew Sanchez, Matthew Zock, Dennis J. Paustenbach
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY
(2016)
Article
Public, Environmental & Occupational Health
Amanda Burns, Jennifer (Mi) Shin, Ken M. Unice, Shannon H. Gaffney, Marisa L. Kreider, Richard H. Gelatt, Julie M. Panko
TOXICOLOGY AND INDUSTRIAL HEALTH
(2017)
Article
Engineering, Biomedical
Michael Kovochich, Ernest S. Fung, Ellen Donovan, Kenneth M. Unice, Dennis J. Paustenbach, Brent L. Finley
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2018)
Article
Environmental Sciences
Heather J. Avens, Joshua R. Maskrey, Allison L. Insley, Kenneth M. Unice, Rachel C. D. Reid, Jennifer Sahmel
ARCHIVES OF ENVIRONMENTAL & OCCUPATIONAL HEALTH
(2019)
Article
Multidisciplinary Sciences
Ernest S. Fung, Kenneth M. Unice, Dennis J. Paustenbach, Brent L. Finley, Michael Kovochich
SCIENTIFIC REPORTS
(2018)
Article
Environmental Sciences
K. M. Unice, M. P. Weeber, M. M. Abramson, R. C. D. Reid, J. A. G. van Gils, A. A. Markus, A. D. Vethaak, J. M. Panko
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Article
Environmental Sciences
K. M. Unice, M. P. Weeber, M. M. Abramson, R. C. D. Reid, J. A. G. van Gils, A. A. Markus, A. D. Vethaak, J. M. Panko
SCIENCE OF THE TOTAL ENVIRONMENT
(2019)
Review
Toxicology
Michael Kovochich, Brent L. Finley, Rachel Novick, Andrew D. Monnot, Ellen Donovan, Kenneth M. Unice, Ernest S. Fung, David Fung, Dennis J. Paustenbach
CRITICAL REVIEWS IN TOXICOLOGY
(2018)
Article
Food Science & Technology
S. M. Benson, K. M. Unice, M. E. Glynn
FOOD AND CHEMICAL TOXICOLOGY
(2019)
Article
Public, Environmental & Occupational Health
Amanda M. Burns, Christy A. Barlow, Amber M. Banducci, Kenneth M. Unice, Jennifer Sahmel
Article
Public, Environmental & Occupational Health
Stacey M. Benson, Joshua R. Maskrey, Melanie D. Nembhard, Kenneth M. Unice, Mark A. Shirley, Julie M. Panko
ANNALS OF WORK EXPOSURES AND HEALTH
(2019)
Article
Environmental Sciences
Kenneth M. Unice, Michael Kovochich, Andrew D. Monnot
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Review
Toxicology
Alice A. Han, Amanda N. Buerger, Hannah Allen, Melissa Vincent, Stephanie A. Thornton, Kenneth M. Unice, Andrew Maier, Antonio Quinones-Rivera
Summary: Although ingestion of ethanol during pregnancy has detrimental effects on the fetus, the potential developmental effects of maternal ethanol intake during lactation are less well characterized. However, the investigation suggests that the use of alcohol-based hand sanitizers by breastfeeding women is unlikely to cause neurodevelopmental issues in infants.
JOURNAL OF APPLIED TOXICOLOGY
(2022)
Article
Food Science & Technology
Skyler A. Price, Mark A. Maddaloni, Brent L. Finley, Stephanie A. Thornton, Ken M. Unice
Summary: The U.S. FDA proposed lead action levels for baby and child food based on a daily dietary Pb reference value of 2.2 μg/day. Biokinetic models were compared to understand potential exposures to Pb in baby food. Soil and dust were found to be the primary contributors to infant blood lead levels, while food and water had a minor contribution.
Review
Cardiac & Cardiovascular Systems
Ernest S. Fung, Andrew Monnot, Michael Kovochich, Kenneth M. Unice, Brooke E. Tvermoes, David Galbraith, Brent L. Finley, Dennis J. Paustenbach
CARDIOVASCULAR TOXICOLOGY
(2018)