Article
Chemistry, Medicinal
Jiu Ai, Matthew Hassink, Kenneth M. Taylor, Victoria Nicole Deycard, Bryan Hearn, Katrice Williams, Megan McGuigan, Liza Valentin-Blasini, Clifford H. Watson
Summary: The study measured the mainstream smoke yields of hydrogen cyanide and aromatic amines from 60 little cigar brands, finding that little cigars have 1.5 to 3 times higher yields of these compounds compared to conventional cigarettes, potentially leading to increased health concerns for smokers.
CHEMICAL RESEARCH IN TOXICOLOGY
(2022)
Article
Behavioral Sciences
Walter Royal, Joseph Bryant, Harry Davis, Ming Guo
Summary: Female and Tg rats exposed to nicotine-free CS showed higher total distances. Female rats in the control group and nicotine-free CS-exposed group exhibited higher total distances and center field measures.
BEHAVIOURAL BRAIN RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Valerii A. Menshov, Aleksei V. Trofimov, Alla V. Zagurskaya, Nadezda G. Berdnikova, Olga I. Yablonskaya, Anna G. Platonova
Summary: The effects of nicotine and alternative nicotine delivery systems (ANDS) on the autonomic nervous system and hormonal system were investigated. The study found that nic-packs showed relatively small changes compared to other ANDS, and they demonstrated superior biological safety.
Review
Substance Abuse
Anna Podlasek, Ravinder Claire, Katarzyna A. Campbell, Sophie Orton, Ross Thomson, Tim Coleman
Summary: This study found that concurrent smoking and nicotine replacement therapy (NRT) use leads to lighter smoking, lower nicotine body fluid levels, and lower exhaled carbon monoxide concentrations. When NRT is used before quitting, there is a significant reduction in exhaled carbon monoxide levels. There is no evidence to support the idea that concurrent smoking and NRT use increase nicotine exposure.
Article
Chemistry, Medicinal
Huihua Ji, Zhenyu Jin, Laura Fenton, Stacey Slone
Summary: This study analyzed the levels of aromatic amines in commercial cigars and found significant variations among different products. Aromatic amines showed a positive correlation with total particulate matter and proteins, with water-insoluble proteins making a greater contribution to their formation.
CHEMICAL RESEARCH IN TOXICOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Isabelle Ruedisueli, Karishma Lakhani, Randy Nguyen, Jeffrey Gornbein, Holly R. Middlekauff
Summary: This study found that in people who smoke tobacco cigarettes, using an electronic cigarette acutely and significantly prolongs several metrics of ventricular repolarization, and this adverse effect on repolarization is found only in male, not female, smokers.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2023)
Article
Substance Abuse
Stellena Mathiaparanam, Biban Gill, Thirunavukkarasu Sathish, Guillaume Pare, Koon K. Teo, Salim Yusuf, Philip Britz-McKibbin
Summary: Tobacco smoking is a leading cause of premature death worldwide. This study examined the association between urinary thiocyanate levels and smoking status in a diverse population of smokers from 14 countries. The results showed that urinary thiocyanate was positively correlated with cigarette consumption and may be a more reliable biomarker of active smoking compared to cotinine. Regional cutoff values were established to improve the detection of smoking status in different countries. In conclusion, urinary thiocyanate has the potential to provide more accurate estimates of tobacco smoking hazards across countries with varying levels of socioeconomic development.
NICOTINE & TOBACCO RESEARCH
(2023)
Article
Multidisciplinary Sciences
Malshani Lakshika Pathirathna, Buddhini Piumi Pabasara Samarasekara, Charitha Mendis, Chandraratne Mahinda Bandara Dematawewa, Kayako Sekijima, Mieko Sadakata, Yoshiyuki Muramatsu, Naoshi Fujiwara
Summary: This study examines the relationship between biomass fuel smoke exposure and anemia in non-pregnant reproductive-aged women in Sri Lanka. The findings suggest no impact of solid fuel smoke exposure on anemia among non-pregnant, reproductive-aged women.
Article
Substance Abuse
Brittney Keller-Hamilton, Mahmood A. Alalwan, Hayley Curran, Alice Hinton, Lauren Long, Kirsten Chrzan, Theodore L. Wagener, Leanne Atkinson, Sriya Suraapaneni, Darren Mays
Summary: This study compared the differences in nicotine delivery and craving relief between oral nicotine pouches (ONPs) and cigarettes. The results showed that ONPs with a nicotine concentration of 6 mg delivered more plasma nicotine at 30 minutes compared to ONPs with a concentration of 3 mg or cigarettes. However, neither ONPs provided as strong craving relief at 5 minutes as cigarettes did.
Article
Substance Abuse
L. M. Snell, T. DeAtley, J. W. Tidey, S. M. Colby, R. N. Cassidy
Summary: Public health officials in the U.S. and New Zealand are considering reducing the nicotine content in cigarettes to reduce their addictive potential. This study aimed to evaluate the effects of nicotine reduction on the reinforcing efficacy of cigarettes in adolescent smokers, which has implications for the success of this policy.
DRUG AND ALCOHOL DEPENDENCE
(2023)
Article
Neurosciences
Ranjithkumar Chellian, Isaac Wilks, Brandon Levin, Song Xue, Azin Behnood-Rod, Ryann Wilson, Megan McCarthy, Abhigyan Ravula, Hardik Chandasana, Hartmut Derendorf, Adriaan W. Bruijnzeel
Summary: The experiment found that exposure to tobacco smoke enhances brain reward function, but does not potentiate the rewarding effects of nicotine in male and female rats.
PSYCHOPHARMACOLOGY
(2021)
Article
Environmental Sciences
Chieh-Ming Wu, Chi (Chuck) Song, Ryan Chartier, Jacob Kremer, Luke Naeher, Olorunfemi Adetona
Summary: Wildland firefighters in the Midwest are exposed to higher levels of wildland fire smoke during prescribed burns compared to those in the western and southeastern United States. Concentrations of carbon monoxide and particulate matter are elevated in the Midwest region. There are differences in exposures among firefighters performing different tasks, and trace metal levels are mostly below safety limits.
ENVIRONMENTAL RESEARCH
(2021)
Article
Chemistry, Medicinal
Selvin H. Edwards, Matthew D. Hassink, Kenneth M. Taylor, Clifford H. Watson, Peter Kuklenyik, Brett Kimbrell, Liqun Wang, Patrick Chen, Liza Valentin-Blasini
Summary: Cigars, especially little cigars, contain higher levels of tobacco-specific nitrosamines (TSNAs) such as NNK and NNN in their mainstream smoke compared to commercial cigarettes. The study measured the quantities of TSNAs in the tobacco filler and mainstream smoke of 60 commercial little cigars using LC-MS/MS, showing a 3- to 5-fold increase in NNK and NNN yields in little cigars compared to previously tested cigarettes.
CHEMICAL RESEARCH IN TOXICOLOGY
(2021)
Article
Psychology, Clinical
Amanda M. Palmer, Leslie E. Sawyer, Thomas H. Brandon
Summary: This study examined the effects of nicotine delivery and sensorimotor stimuli on cravings and immediate outcomes of e-cigarette use. The results showed moderate effects for nicotine and smaller effects for sensorimotor stimuli on cravings. Participants using altered sensorimotor apparatus reported greater craving reduction compared to those using normal e-cigarettes.
ADDICTIVE BEHAVIORS
(2021)
Article
Neurosciences
In Soo Ryu, Jieun Kim, Ju Hwan Yang, Su Yeon Seo, Sumin Sohn, Sunghyun Kim, Kyuhong Lee, Joung-Wook Seo, Eun Sang Choe
Summary: The study found that non-nicotine alkaloids in commercial cigarette smoke act synergistically with nicotine, upregulating glutamatergic response in the dorsal striatum, which contributes to the hypersensitization of psychomotor behaviors.
Article
Engineering, Chemical
Maria del Mar Olaya, Paloma Carbonell-Hermida, Marina Trives, Juan A. Labarta, Antonio Marcilla
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2020)
Article
Thermodynamics
Emilio Calabuig, Antonio Marcilla
Summary: The study measured the composition of evolved slow pyrolysis products under inert and oxidising atmospheres of reference tobacco from the University of Kentucky and its mixture with an SBA-15 mesoporous silica. The results showed that the addition of SBA-15 affects the types and quantities of pyrolysis products of tobacco, suggesting potential reduction of toxicity in heat-not-burn tobaccos for consumers.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2021)
Article
Thermodynamics
Paloma Carbonell-Hermida, Antonio Marcilla, Maria del Mar Olaya
Summary: During LLE data correlation, the behavior of models in completely miscible binary mixtures is often overlooked, leading to inconsistent results. Commercial tools like Aspen Plus may provide misleading correlations, while developing custom tools can ensure consistent parameters.
FLUID PHASE EQUILIBRIA
(2021)
Article
Chemistry, Physical
Nerea Juarez-Serrano, Javier Asensio, Inmaculada Blasco, Maribel Beltran, Antonio Marcilla
Summary: This study investigated the impact of synthesis conditions on the use of SBA-15 as a tobacco additive to reduce toxic and carcinogenic components in tobacco smoke. The optimal conditions of 24 hours synthesis time, 40 degrees Celsius temperature, and 700 rpm stirring rate yielded significant reductions in tar, nicotine, and CO. Long fibers and increased synthesis time were found to improve tar reduction efficiency, showcasing promising results for potential industrial-scale application.
Article
Chemistry, Physical
Nerea Juarez-Serrano, Desire Berenguer, Isabel Martinez-Castellanos, Inmaculada Blasco, Maribel Beltran, Antonio Marcilla
Summary: The synthesis of SBA-15 using sodium silicate as precursor has been optimized, with hydrothermal treatment found to be crucial for obtaining materials with adequate performance. A 24-hour hydrothermal treatment results in materials with the best properties, while a reaction time between 1 and 2 hours shows the best performance in reducing toxicity in tobacco smoking products.
Article
Chemistry, Analytical
Elena Banon, Angela N. Garcia, Antonio Marcilla
Summary: The thermal behavior analysis of leather from different animal species and tanning processes was conducted to discriminate them. Results show significant differences in the outcomes obtained from the analysis techniques depending on treatments and animal species.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2021)
Article
Thermodynamics
Emilio Calabuig, Antonio Marcilla
Summary: The study found that the addition of catalyst under oxidising atmosphere and at low temperatures significantly decreased the formation of pyrolysis products, while under inert atmosphere and at high temperatures, it did not have a significant impact on the formation of pyrolysis products.
THERMOCHIMICA ACTA
(2021)
Article
Thermodynamics
Antonio Marcilla, Maria del Mar Olaya, Paloma Carbonell-Hermida, Marta K. Wojtczuk, Hector Rodriguez, Eva Rodil, Ana Soto
Summary: Several physical properties and isobaric vapor-liquid equilibria were measured for a binary system of acetone and the ionic liquid 1-ethyl-3-methyl-imidazolium acetate. Liquid-liquid equilibria data were also measured. The study proposed a new model with a correction term based on the analysis of excess Gibbs energy, which could simultaneously correlate both sets of equilibrium data with high accuracy.
FLUID PHASE EQUILIBRIA
(2022)
Article
Chemistry, Analytical
A. Marcilla, D. Berenguer, I. Martinez
Summary: Five potential additives, including three zeolites and two silicates, have been studied for reducing harmful compounds generated when smoking Heet tobacco. The results show that USY and SBA-15 additives exhibit significant reductions, with SBA-15 showing the largest reduction in total particle matter.
JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
(2022)
Article
Engineering, Chemical
Juan A. Labarta, Maria M. Olaya, Antonio F. Marcilla
Summary: This study analyzes the characteristics of the nonrandom two-liquids model (NRTL) and investigates its relation with binary interaction parameters and phase equilibria. Empirical equations are established to simulate the trajectories of different miscibility boundaries.
Article
Chemistry, Multidisciplinary
Javier Asensio, Maria Isabel Beltran, Nerea Juarez-Serrano, Deseada Berenguer, Antonio Marcilla
Summary: The use of tobacco biomass as an energy source is becoming increasingly important. This study investigates the decomposition of NNN and the effects of SBA-15 and MCM-41 under different conditions. The results show that SBA-15 has the best catalytic reduction effect under pyrolysis conditions.
APPLIED SCIENCES-BASEL
(2022)
Article
Chemistry, Multidisciplinary
Pablo Londono-Larrea, Estefania Villamarin-Barriga, Angela N. Garcia, Antonio Marcilla
Summary: The thermal decomposition of cocoa pod husks was studied under inert and oxidizing atmospheres. The results provide insight into the decomposition behavior and optimal operating conditions for maximizing the mass fraction of different functional groups.
APPLIED SCIENCES-BASEL
(2022)
