Article
Plant Sciences
Duilio Iamonico
Summary: This article addresses the nomenclatural and taxonomic issues surrounding Amaranthus caudatus and its related taxa. Neotypes and lectotypes are designated for various names, and several names are considered as synonyms of A. caudatus. Based on morphological, cytological, and molecular data, the taxa caudatus, mantegazzianus, and gibbosus are suggested to be treated as distinct species. A new name, Amaranthus baileyanus, is proposed for A. caudatus var. gibbosus due to a previously validly published Amaranthus gibbosus.
Article
Medicine, Research & Experimental
Tomislav Kostic, Dejan Popovic, Zoran Perisic, Dragana Stanojevic, Sonja Dakic, Sandra Saric, Danijela Djordjevic Radojkovic, Svetlana Apostolovic, Nenad Bozinovic, Snezana Ciric Zdravkovic, Stefan Milutinovic, Bojan Maricic, Nikola Zivkovic, Mladjan Golubovic, Miodrag Djordjevic, Radomir Damjanovic, Abraham Bell, Boris Dindic
Summary: The study demonstrates that aminoguanidine has a significant hepatoprotective effect in acute liver damage induced by CCl4, attributed to its antioxidant effects, inhibition of pro-oxidative and pro-inflammatory mediators, and induction of damaged hepatocytes into apoptosis.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Medicine, Research & Experimental
Muhammed Amanat, Md Sharif Reza, Md Sadikur Rahman Shuvo, Khondoker Shahin Ahmed, Hemayet Hossain, Muhammad Tawhid, Md Saifuzzaman, Mohammad Shariful Islam, Tanoy Mazumder, Md Amirul Islam, A. F. M. Shahid Ud Daula
Summary: The study evaluated the hepatoprotective effects of Zingiber roseum rhizome extract in CCl4 induced hepatotoxicity in mice. Seven phenolic compounds in the extract showed potential for inhibiting ROS production and displayed various biological activities, including antioxidant and hepato-protective activities.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Chemistry, Multidisciplinary
Shameenii A. P. P. Thanebal, Senty Vun-Sang, Mohammad Iqbal
Summary: The study demonstrated that Pandanus amaryllifolius has antioxidant properties and can protect rats from acute hepatic damage caused by carbon tetrachloride. The extract contains various phytochemical constituents, showing significant antioxidant enzyme activity and reducing the extent of liver damage.
ARABIAN JOURNAL OF CHEMISTRY
(2021)
Article
Medicine, Research & Experimental
Neelum Iqbal, Hafiz Muhammad Zubair, Mikhlid H. Almutairi, Muhammad Abbas, Muhammad Furqan Akhtar, Lotfi Aleya, Mohamed Kamel, Ammara Saleem, Qaiser Jabeen, Sobia Noreen, Mirza Muhammad Faran Ashraf Baig, Mohamed M. Abdel-Daim
Summary: Cordia rothii Roem. & Schult. possesses strong antioxidant and hepatoprotective activities, which may involve the Nrf2-NF kappa B pathways.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Darya Pon'kina, Sergey Kuranov, Mikhail Khvostov, Nataliya Zhukova, Yulia Meshkova, Mariya Marenina, Olga Luzina, Tatyana Tolstikova, Nariman Salakhutdinov
Summary: In this study, the compound QS-528, previously discovered as an agonist of FFAR1, was found to have a hepatoprotective effect against CCl4-induced liver injury. It reduced the levels of liver enzymes, improved liver tissue degeneration and necrosis, and promoted liver regeneration.
Review
Biochemistry & Molecular Biology
Balu Alagar Venmathi Maran, Mohammad Iqbal, Prakash Gangadaran, Byeong-Cheol Ahn, Pasupuleti Visweswara Rao, Muhammad Dawood Shah
Summary: Medicinal plants, such as Andrographis paniculata, Bauhinia purpurea, Commelina nudiflora, Dillenia suffruticosa, Elaeis guineensis, Lygodium microphyllum, and Nephrolepis biserrata, have been reported to have hepatoprotective properties due to their phytochemical composition. These plants contain various compounds, including alkaloids, saponins, flavonoids, tannins, terpenoids, steroids, polyphenols, and diterpenoid lactones, which contribute to their antioxidant, anti-inflammatory, immunomodulatory, and hepatoprotective effects.
Article
Plant Sciences
Duilio Iamonico, Amara Noor Hussain, Arya Sindhu, Venugopalan Nair Saradamma Anil Kumar, Shabnum Shaheen, Mamoona Munir, Paola Fortini
Summary: Amaranthus is a taxonomically complex genus due to its high morphological variability, which results in nomenclatural disorders and misidentifications. Seed micromorphology shows promise in the taxonomy of Amaranthus, but current investigations are limited. In this study, a detailed SEM analysis was conducted on 25 Amaranthus taxa, revealing interesting new taxonomic data. Several seed types were identified, but some species within the deflexus-type were not distinguishable based on seed features. A diagnostic key for the studied taxa was proposed, but subgenera could not be distinguished using seed features, confirming previous molecular data.
Article
Food Science & Technology
Ya-Ting Chen, Chao-Wen Tu, Chih-Yao Hou, Yu-An Chen, Ruo-Qi Xu, Chia-Hung Kuo, Chih-Chung Wu, Shu-Ling Hsieh
Summary: The study investigated the hepatoprotective effect of egg protein hydrolysate (EWH) by regulating antioxidant enzyme expression using in vitro and in vivo models. The results showed that EWH enhanced antioxidant activity in HepG2 cells and alleviated hepatotoxicity in rats induced by carbon tetrachloride. EWH also ameliorated liver tissue injuries and had the highest glutamic acid content in its amino acid composition.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2023)
Article
Nutrition & Dietetics
Adebimpe Esther Ofusori, Roshila Moodley, Sreekantha B. Jonnalagadda
Summary: The study examined the nutritional value, phytochemical constituents, antioxidant, and antiulcer activities of Achyranthes aspera and Amaranthus spinosus. A. spinosus leaves were found to contribute significantly to the dietary intake of iron, making them suitable for treating chronic anemia. Arsenic, cadmium, and lead were undetected in the leaves of the two species, suggesting their potential use as nutraceuticals in South Africa.
CURRENT TOPICS IN NUTRACEUTICAL RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Dac Thang Hoang, Thi Thu Hien Truong, Ngo Viet Duc, Le Tuan Anh Hoang, Thi Thao Do, Le Ba Vinh, Seo Young Yang, Gao Dan, Le Tuan Anh
Summary: Helicteres hirsuta Lour. is a traditional Vietnamese medicine used for treating chronic liver diseases. Research has shown that its extracts have hepatoprotective effects, reducing liver damage and cirrhosis.
APPLIED SCIENCES-BASEL
(2021)
Article
Food Science & Technology
Lucelia Vieira Pereira, Maiara Rodrigues Salvador, Beatriz Souza Silva, Helena Maria Pinheiro-Sant'Ana, Ceres Mattos Della Lucia, Reinaldo Duque Brasil Landulfo Teixeira, Leandro de Morais Cardoso
Summary: This study aimed to determine the composition and micronutrient profile of Caruru and trapoeraba grown in Brazil. The leaves of Caruru contained high dietary fiber, potassium, iron, and β-carotene, while the leaves of trapoeraba were rich in potassium, iron, calcium, zinc, ascorbic acid, and β-carotene.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Plant Sciences
Cheng Wang, Cheng Ma, Ke Fu, Yanfang Liu, Lihong Gong, Cheng Peng, Yunxia Li
Summary: The study shows that phillygenin in Forsythiae fructus has hepatoprotective, anti-inflammatory, and antioxidant effects. By modulating gut microbiota and metabolites, phillygenin can mitigate carbon tetrachloride-induced liver fibrosis and improve intestinal barrier function.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Plant Sciences
Arun Kumar Mishra, Piyush Chahal, Harpreet Singh, Arvind Kumar, Amrita Mishra
Summary: The study validated the traditional claims of Senna occidentalis L. roots in hepatoprotective and antidiabetic activity, showing significant effects in protecting the liver and reducing blood glucose levels. The compound quercetin was identified as a key component responsible for these activities.
SOUTH AFRICAN JOURNAL OF BOTANY
(2022)
Article
Pharmacology & Pharmacy
E. S. Said, A. H. Mohammed, H. M. Ali, A. Y. Babiker, R. Alnughaymishi, N. Z. Althaqeel, A. S. Ahmed
Summary: The protective effects of sodium copper chlorophyllin and nebivolol were evaluated in a mice model of CCL4 induced hepatotoxicity. Co-administration of either silymarin, nebivolol, or sodium copper chlorophyllin with CCl4 ameliorated hepatic injury through their anti-inflammatory and antioxidant activities.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
