Article
Fisheries
Yucai Pan, Jinqiang Huang, Yongjuan Li, Shenji Wu, Lu Zhao
Summary: This study used RNA sequencing technology to analyze the transcriptome profiles in spleens of rainbow trout infected and uninfected with infectious hematopoietic necrosis virus (IHNV). A total of 9144 differentially expressed genes (DEGs) were identified, with most DEGs significantly enriched in major immune terms and signaling pathways. The expression levels of six key immune-related genes in four important immune signaling pathways were also detected. The results provide a better understanding of the dynamic immune response of rainbow trout infected with IHNV and lay a foundation for further study of molecular mechanisms of anti-IHNV innate immunity.
AQUACULTURE REPORTS
(2023)
Article
Immunology
Zhi-Shuai Hou, Yuan-Ru Xin, Xiao-Dong Yang, Chu Zeng, Hong-Kui Zhao, Meng-Qun Liu, Mei-Zhao Zhang, Jeffrey G. Daniel, Ji-Fang Li, Hai-Shen Wen
Summary: Our study revealed that both asymptomatic and symptomatic rainbow trout showed activated immunomodulatory genes in the cytokine network, with downregulated glucocorticoid and mineralocorticoid receptors. Asymptomatic trout specifically activated complement- and TNF-associated immune defenses in response to Vibrio anguillarum infection. On the other hand, the complement and coagulation cascades, as well as steroid hormone homeostasis in symptomatic trout, were disturbed by V. anguillarum infection. The findings provide new insights into the regulatory mechanisms of stress and immune responses in rainbow trout.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Sarker Mohammed Ibrahim Khalil, Elena Sacca, Marco Galeotti, Simona Sciuto, Nadia Stoppani, Pier Luigi Acutis, Rafet Cagri Ozturk, Konstantina Bitchava, Maria Del Mar Blanco, Lucio Fariano, Marino Prearo, Silvia Colussi, Donatella Volpatti
Summary: Italian rainbow trout farms often experience outbreaks of lactococcosis caused by Lactococcus garvieae, with both asymptomatic and symptomatic fish present in rearing basins. This study aimed to examine immune-related gene expression and investigate Near Infrared Spectroscopy (NIR) as a tool for distinguishing between infected and healthy fish. The results showed significant differences in gene expression between symptomatic and asymptomatic fish, particularly for cytokines IL-1 beta and IL-8. NIR scanning successfully differentiated between the two fish groups. This study also demonstrated the importance of specific gene expression patterns in the trout immune system's response to L. garvieae infection.
Article
Fisheries
Lu Zhao, Jinqiang Huang, Yongjuan Li, Shenji Wu, Yujun Kang
Summary: In this study, the immune response of rainbow trout to infectious hematopoietic necrosis virus (IHNV) was investigated. The study measured changes in immune parameters, transcriptome profiles, and gene expression patterns in rainbow trout gill following IHNV challenge. The results demonstrated that various immune-related genes were significantly up-regulated during infection, suggesting a strong immune response to IHNV. The study provides new insights into the immune regulation mechanisms and disease resistance breeding studies in rainbow trout.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Tongzhen Sun, Jinqiang Huang, Lirui Zhu, Shenji Wu, Lu Zhao, Yujun Kang
Summary: This study analyzed the mRNA and miRNA expression profiles in rainbow trout head kidney after IHNV infection using RNA-seq and identified key immune-related genes and miRNAs. The results showed that IHNV infection up-regulated numerous immune-related genes and identified miRNAs that target immune-related genes.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Immunology
Shenji Wu, Jinqiang Huang, Yongjuan Li, Mingquan Lei, Lu Zhao, Zhe Liu
Summary: This study investigated the immune defense mechanisms of rainbow trout against infectious hematopoietic necrosis virus (IHNV). Through biochemical methods, RNA-seq, and qRT-PCR, the researchers observed significant changes in immune-related gene expression and immune parameters in rainbow trout infected with IHNV. They also identified miRNAs that target key immune-related genes. These findings contribute to a better understanding of the immune mechanisms in rainbow trout against IHNV.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
Josef Vaclavik, Pavla Sehonova, Jana Blahova, Denisa Medkova, Eva Postulkova, Ondrej Maly, Michaela Charvatova, Kamil Stastny, Jiri Lenz, Jan Mares, Ales Franc, Zdenka Svobodova
Summary: The aim of this study was to investigate the effects of foodborne fluoxetine on juvenile rainbow trout. The results showed significant changes in hematological profile, liver and kidney detoxifying enzyme activity, and damage to the proximal tubules of the caudal kidney, confirming the importance of its impact on immune response.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Di Wang, Simeng Sun, Shaowu Li, Tongyan Lu, Dongfang Shi
Summary: This study conducted transcriptomic profiling of spleen samples from rainbow trout at 24 h post-Y. ruckeri infection and identified 2498 differentially expressed genes related to immune response pathways. The findings provide insight into the molecular mechanisms of rainbow trout immune responses to Y. ruckeri infection.
Article
Fisheries
Shenji Wu, Jinqiang Huang, Yongjuan Li, Zhe Liu, Qian Zhang, Yucai Pan, Xiaolan Wang
Summary: The study explored the relationship between tyrp1a and tyrp2 expression and body colour variation in rainbow trout, revealing significant differences in expression levels of these genes in different developmental stages and tissues, as well as between wild-type and yellow mutant rainbow trout. The full-length cDNA sequences of tyrp1a and tyrp2 were obtained, encoding proteins with conserved domains. Amino acid sequence comparisons showed higher conservation among fishes, and qRT-PCR analysis indicated varying expression levels in different tissues and developmental stages, suggesting a close relationship between tyrp1a and tyrp2 expression changes and rainbow trout body colour variation.
AQUACULTURE INTERNATIONAL
(2021)
Article
Fisheries
Lu Zhao, Jinqiang Huang, Yongjuan Li, Shenji Wu, Yujun Kang
Summary: Rainbow trout is an economically important fish cultivated worldwide, but the outbreak of infectious hematopoietic necrosis virus (IHNV) hampers its farming industry and causes economic losses. This study identified numerous immune-related genes in the skin of rainbow trout infected with IHNV, providing insights into the innate immune system and laying a foundation for further research on disease resistance breeding.
AQUACULTURE INTERNATIONAL
(2023)
Article
Physiology
Irene Garcia-Meilan, Lluis Tort, Ali Reza Khansari
Summary: The study aimed to determine the integrated stress response in rainbow trout after acute hypoxia. The results showed that physiological responses were significantly affected by hypoxic stress and their interaction with time after the challenge. The study also revealed the importance of different elements and areas of the stress response, including systemic and mucosal responses, in maintaining homeostasis.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Seyed Hossein Hoseinifar, Ghasem Rashidian, Hamed Ghafarifarsani, Mohammad Amin Jahazi, Mehdi Soltani, Hien Van Doan, Ehab El-Haroun, Marina Paolucci
Summary: The study investigated the dietary effects of apple pomace-derived pectin (APDP) in rainbow trout culture, showing promising improvements in growth performance and immune parameters. The results suggest APDA as a potential beneficial feed additive for rainbow trout.
Article
Fisheries
Megumi Matsumoto, Uwe Fischer, Motohiko Sano, Goshi Kato
Summary: The study shows that rainbow trout lacking CD1 can elicit cell-mediated immune responses against Mycobacterioides salmoniphilum mycolic acids, indicating their potential as vaccine candidates to activate CD8α+ T cells.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Fang Ma, Yali Zou, Langfang Ma, Ruilin Ma, Xin Chen
Summary: In this study, the structure and characteristics of acsl genes were investigated in rainbow trout, and their involvement in biological immunity and hypoxic stress response was explored. It was found that acsl genes were highly conserved in rainbow trout and showed high expression in immune tissues. Furthermore, the expression of acsl genes was upregulated under hypoxia, indicating their role in enhancing tolerance to hypoxia and immune response. These findings provide important insights into teleost evolution and the effects of hypoxia on biological immunity.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
(2022)
Article
Fisheries
Weijun Chen, Shiyang Gao, Yuchao Huang, Kuo Chang, Xiaoyu Zhao
Summary: This study shows that adding Chlorella sorokiniana to the diet of rainbow trout increases feed intake and weight gain rate, improves antioxidant capacity and immune response, and enhances the survival rate of fish infected with Aeromonas salmonicida.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Mohsen Ali, Siyavash Soltanian, Ali Taheri Mirghaed, Mostafa Akhlaghi, Seyed Hossein Hoseinifar, Amin Gholamhosseini
Summary: The research investigates the effects of probiotics derived from kefir on rainbow trout's immune parameters, gene expression, and disease resistance. The findings show that these probiotics can enhance immune functions, reduce mortality rates, and increase expression of immune-related genes, highlighting their potential benefits in aquaculture.
AQUACULTURE RESEARCH
(2022)
Article
Fisheries
Shadi Mighani, Roghieh Safari, Seyed Hossein Hoseinifar, Ali Shabani, Maryam Dadar
Summary: The study revealed that diazinon exposure could disrupt the expression of genes related to spermatogenesis and sex hormones in male zebrafish. The FSH receptor, activin, and endogenous receptor gene expression levels decreased with higher concentrations of diazinon, as did serum hormone levels. These findings suggest that diazinon toxin exposure might negatively impact the reproductive efficiency of zebrafish.
AQUACULTURE RESEARCH
(2022)
Article
Fisheries
Seyyed Morteza Hoseini, Morteza Yousefi, Marzieh Abbasi, Evgeny Vladimirovich Kulikov, Stanislav Gennadievich Drukovsky, Aleksandr Konstantinovich Petrov, Elena Alexandrovna Krotova, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: The present study investigated the effects of taurine and/or methionine addition to a plant-based diet on growth performance, immunological and antioxidant responses of Persian sturgeon. Results showed that both taurine and methionine supplementation significantly improved growth, immune response, and antioxidant capacity. Furthermore, an interaction effect between taurine and methionine was observed in various parameters related to blood, liver, and erythrocyte.
AQUACULTURE NUTRITION
(2022)
Article
Fisheries
Ashkan Ajdari, Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Susan Javahery, Fariborz Narimanizad, Kesinee Gatphayak, Hien Van Doan
Summary: Prebiotics, probiotics, and synbiotics in fish diets can improve growth performance, immune system, antioxidant capacity, and digestion. They also reduce the need for therapeutic treatment in fish.
AQUACULTURE NUTRITION
(2022)
Article
Fisheries
Ruth Escamilla-Montes, Genaro Diarte-Plata, Gabriela B. Mendoza-Maldonado, Aaron Barraza, Carlos Angulo, Seyed Hossein Hoseinifar, Jesus A. Fierro-Coronado, Antonio Luna-Gonzalez
Summary: Invertebrates' immune defense mechanisms have a critical role in pathogen recognition and elimination. This study focused on the transcriptome analysis of Argopecten ventricosus to identify immune-related genes. The results showed that probiotic bacilli can significantly increase the expression of certain immune-related genes.
LATIN AMERICAN JOURNAL OF AQUATIC RESEARCH
(2022)
Article
Fisheries
Mohammad Arghideh, Seyed Hossein Hoseinifar, Reza Ghorbani Nasrabadi, Mohammad Mazandarani, Ehab El-Haroun, Hien Van Doan
Summary: This study investigates the effects of soil-derived Streptomyces chartreusis KU324443 as a probiotic on the growth performance, immune parameters, and gene expression in common carp. The results show that feeding carps with S. chartreusis-supplemented diet improves growth performance and enhances immune responses, as well as alters the expression of immune and antioxidant-related genes.
AQUACULTURE NUTRITION
(2022)
Article
Fisheries
Milad Maniat, Amir Parviz Salati, Nasim Zanguee, Seyed Mohammad Mousavi, Seyed Hossein Hoseinifar
Summary: The study aimed to examine the synbiotic effects of Pediococcus acidilactici (PA) and isomaltooligosaccharide (IMO) on the growth and immunity of juvenile common carp. The results showed that the diet supplemented with 1 g/kg PA and 5 g/kg IMO significantly improved the growth performance and immune responses of the fish. Therefore, the combination of PA and IMO can be recommended as a beneficial synbiotic additive and immunostimulant in juvenile common carp.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Hamed Ghafarifarsani, Shiva Nedaei, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: This study investigates the effects of chlorogenic acid (ChA) in the diet on the growth performance, digestive enzyme activity, immunological variables, and disease resistance of rainbow trout juveniles. The findings show that the group receiving 600 mg kg(-1) ChA-supplemented diet demonstrates the lowest feed conversion ratio and highest specific growth rate. The results suggest that ChA can improve the growth parameters, immune indices, antioxidant capacity, and disease resistance in rainbow trout.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Hamed Ghafarifarsani, Seyed Hossein Hoseinifar, Taravat Molayemraftar, Mahdieh Raeeszadeh, Hien Van Doan
Summary: The study found that adding pot marigold powder at 1%, 1.5%, and 2% levels to the diet of rainbow trout significantly improved growth, immune response, and disease resistance. In addition, the 1% and 1.5% MP groups showed increased digestive enzyme activities and antioxidant capacity. The highest survival rate after Yersinia ruckeri infection was observed in the 1.5% MP group compared to the control group.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Kobra Armobin, Ehsan Ahmadifar, Hossein Adineh, Mahsa Naderi Samani, Naser Kalhor, Sevdan Yilmaz, Seyed Hossein Hoseinifar, Hien Van Doan
Summary: This study aimed to evaluate the effects of different levels of quercetin on the growth performance, immune responses, antioxidant status, serum biochemical factors, and high-temperature stress responses in common carp. The results showed that feeding diets supplemented with 400-600 mg/kg quercetin improved growth performance, immunity, and antioxidant status, and increased tolerance to heat stress in common carp.
AQUACULTURE NUTRITION
(2023)
Review
Agriculture, Dairy & Animal Science
Seyed Hossein Hoseinifar, Francesca Maradonna, Mehwish Faheem, Ramasamy Harikrishnan, Gunapathy Devi, Einar Ringo, Hien Van Doan, Ghasem Ashouri, Giorgia Gioacchini, Oliana Carnevali
Summary: Ornamental fish husbandry faces challenges and losses, such as transport stress and disease outbreaks. This review discusses measures to prevent or control fish diseases and the role of natural and sustainable microbial feed additives (such as probiotics, prebiotics, and synbiotics) in enhancing the health, reducing transport stress, and promoting growth and reproduction of farmed ornamental fish. The review aims to fill the knowledge gap in advanced and sustainable practices in ornamental fish production.
Article
Agriculture, Dairy & Animal Science
Dara Bagheri, Rohullah Moradi, Mahyar Zare, Ebrahim Sotoudeh, Seyed Hossein Hoseinifar, Amin Oujifard, Noah Esmaeili
Summary: This study investigated the effects of low molecular weight sodium alginate (LMWSA) on the growth and health of whiteleg shrimp, as well as its potential in alleviating negative impacts of cadmium. The results showed that LMWSA improved feed conversion ratio and antioxidant parameters, and prevented the suppression of antioxidant system parameters caused by cadmium. The 2.0 LMWSA treatment had the best performance in various parameters, and increasing LMWSA levels gradually is recommended.
Article
Fisheries
Allieh Bairami Igdery, Mohammad Farhangi, Hossein Adineh, Hojatollah Jafaryan, Zia Kordjazi, Seyed Hossein Hoseinifar
Summary: Herbal treatment with ginger powder enhances the immune and antioxidant responses, improves growth, and increases stress resistance in Caspian roach. The inclusion of 10 and 20 g/kg ginger powder in the diet shows the most significant effects on the final weight, specific growth rate, antioxidant enzyme activity, and immune indices. Ginger can be considered as a beneficial supplement for promoting the overall health and survival of this endangered fish species.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Majid Khanzadeh, Babak Beikzadeh, Seyed Hossein Hoseinifar
Summary: This study finds that red macroalgae extract (Laurencia caspica) has positive effects on hematological, immunological, antioxidant, biochemical, and disease resistance of Nile tilapia against S. agalactiae. After 50-day feeding, the white blood cells, hemoglobin, and neutrophils of fish significantly increased. Immunological parameters (including IgM and C3) were also significantly higher in the treated groups. Additionally, the extract intake significantly increased antioxidant enzyme activities and improved survival rates of fish infected with S. agalactiae.
AQUACULTURE NUTRITION
(2023)
Article
Fisheries
Mehwish Faheem, Rafia Jamal, Nadia Nazeer, Saba Khaliq, Seyed Hossein Hoseinifar, Hien Van Doan, Marina Paolucci
Summary: The present study found that supplementation of Spirulina in the diet of grass carp has positive effects on growth, digestive enzymes, antioxidants, and innate immunity. Specifically, adding 1% and 5% Spirulina in the diet promotes growth, increases intestinal digestive enzyme activity, reduces hepatic lipid peroxidation, enhances hepatic antioxidant enzyme activity and glutathione levels, and boosts immune function in the skin mucus of fish.
