Article
Biochemistry & Molecular Biology
David G. Valcarce, Marta F. Riesco, Juan Manuel Martinez-Vazquez, Jose Luis Rodriguez Villanueva, Vanesa Robles
Summary: This experiment aimed to evaluate the potential links between handling during culture with stress responses and growth on Senegalese sole. The results showed that reducing handling-derived stressors led to lower levels of circulating cortisol in the fish and promoted higher growth. The gene expression study further supported the findings of this experiment.
FISH PHYSIOLOGY AND BIOCHEMISTRY
(2023)
Article
Fisheries
Marian Ponce, Eugenia Zuasti, Elena Reales, Victoria Anguis, Catalina Fern
Summary: Infectious diseases are a major cause of social and economic losses in world aquaculture, with bacterial diseases such as photobacteriosis impacting the production of Senegalese sole. This study aimed to develop an oral DNA nanovaccine for S. senegalensis juveniles against Photobacterium damselae subsp. piscicida (Phdp). The results indicate that oral vaccination with CS-TPP+pPDPimpdh NPs may be acting through non-specific immune responses as well as specific humoral and cell mediated immunity, providing a promising step towards developing an oral DNA nanovaccine against Phdp in sole.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Environmental Sciences
Mario J. Araujo, Amadeu M. V. M. Soares, Marta S. Monteiro
Summary: Exposure to 4-MBC during metamorphosis accelerated metamorphosis progression and induced adverse effects in S. senegalensis, such as reduced length, inhibited CAT activity, and oxidative damage. These effects persisted even after 9 days in a clean medium, suggesting potential long-term impacts on growth and metamorphic progression in this species.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Environmental Sciences
M. J. Araujo, C. Quintaneiro, R. J. M. Rocha, P. Pousao-Ferreira, A. Candeias-Mendes, A. M. V. M. Soares, M. S. Monteiro
Summary: This study investigated the effects of ultraviolet radiation (UV) and triclosan (TCS) on the metamorphosis of Solea senegalensis, and found that TCS induced malformations, accelerated and delayed metamorphosis, while UV radiation enhanced these effects. The expression of thyroid axis-related genes were down-regulated after TCS exposure and remained down-regulated even after a period in clean media. These stressors may have implications for the ecological performance of the species.
Article
Agriculture, Dairy & Animal Science
Seok-Won Lim, Jung Hwan Jeon, Byeonghwi Lim, Min-Jae Jang, Doo-Hwan Kim, Chan Ho Kim, Jun-Mo Kim
Summary: This study assessed welfare levels related to stocking density using behavioral and physiological parameters, and identified biological mechanisms and immunological expression patterns influenced by stocking density through transcriptome analysis. The results provide comprehensive insights into operational strategies considering stocking density and biomarkers.
JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Fisheries
Lucia Vazquez-Salgado, Jose G. Olveira, Carlos P. Dopazo, Isabel Bandin
Summary: Intensive fish farming at high densities has negative effects on fish welfare, with NNV-infected Senegalese sole reared at high densities showing earlier mortality onset and higher viral load.
JOURNAL OF FISH DISEASES
(2021)
Article
Biochemistry & Molecular Biology
Hua Sun, Ling Zhao, Zi-Jian Xu, Michele De Marco, Mickael Briens, Xiang-Hua Yan, Lv-Hui Sun
Summary: The study aimed to determine if hydroxy-selenomethionine (OH-SeMet) provides better protection for broilers against environmental stress compared to sodium selenite (SS) or seleno-yeast (SY). Results showed that OH-SeMet improved feed conversion ratio and selenium concentration in tissues better than SS and SY. Additionally, OH-SeMet demonstrated better ability to maintain performance, redox, and immune status of broilers under high stocking density and heat stress compared to SS and SY.
Article
Agriculture, Dairy & Animal Science
Xinhui Wang, Tingyang Qin, Hongyang Xu, Peiyao Liu, Yan Wu, Dingran Zhang, Zhili Qi
Summary: The objective of this study was to investigate the effects of different stocking densities on Matou goats. The results showed that high stocking density resulted in a decrease in growth, digestive and immune function of Matou goats.
ITALIAN JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Fisheries
Mohammad Hossein Khanjani, Moslem Sharifinia, Mauricio Gustavo Coelho Emerenciano
Summary: The innate immunity of invertebrates is a valuable foundation for studying the common biological responses to environmental changes. The intensification of aquaculture has led to the overuse of antibiotics and chemotherapeutics, resulting in the emergence of resistant microbes. Biofloc technology (BFT) offers a sustainable and eco-friendly approach to disease management in aquaculture by harnessing the power of antibiotics, probiotics, and prebiotics.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Mohammed M. Qaid, Hamad A. Albatshan, Maged A. Al-Garadi, Elsayed O. S. Hussein
Summary: This experiment investigated the effects of the brooding system and stocking density on the immune response of broiler chicks. The results showed that the two brooding systems had similar effects on the development of chick lymphoid organs and the maintenance of normal stress levels. The higher stocking density resulted in lower live weights and higher ratios of heterophils to lymphocytes. Smarter brooding systems are needed for the poultry industry.
ITALIAN JOURNAL OF ANIMAL SCIENCE
(2023)
Article
Agriculture, Dairy & Animal Science
Marcos Antonio Lopez-Patino, Arleta Krystyna Skrzynska, Fatemeh Naderi, Juan Miguel Mancera, Jesus Manuel Miguez, Juan Antonio Martos-Sitcha
Summary: Chronic stress exposure, such as high stocking density and food deprivation, enhanced the stress response parameters in gilthead sea bream juveniles. The monoaminergic activities in different brain regions helped to reorganize the physiological response to the challenges applied, suggesting a role of brain monoaminergic activity in orchestrating the endocrine response to chronic stress in fish.
Article
Fisheries
K. Koprucu, S. Mise Yonar, S. Koprucu, Me Yonar
Summary: This study examined the effects of different stocking densities on the growth, oxidative stress, antioxidant enzymes, and hematological and immunological values in European catfish. The findings showed that high stocking densities can lead to oxidative stress in fish and have negative impacts on their health and growth.
AQUACULTURE INTERNATIONAL
(2023)
Article
Veterinary Sciences
Xinlei Gao, Jiangang Gong, Bowen Yang, Yanci Liu, Hongjian Xu, Yanshuang Hao, Jialin Jing, Zhihua Feng, Lihua Li
Summary: High stocking density causes oxidative stress and inflammation in broilers, but classical music can alleviate stress to some extent. This study examined the effects of classical music on broilers' growth performance, stress level, antioxidant index, immune function, and meat quality under different stocking densities. The results showed that increasing stocking density decreased feed intake and weight gain, increased feed-to-gain ratio and mortality. It also increased stress hormone levels and decreased immune function and antioxidant activities. However, playing classical music for broilers improved their growth performance and decreased stress levels.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Microbiology
Marta Dominguez-Maqueda, Isabel M. Cerezo, Silvana Teresa Tapia-Paniagua, Ines Garcia De La Banda, Xabier Moreno-Ventas, Miguel Angel Morinigo, Maria Carmen Balebona
Summary: Concerns regarding the safety, applicability, and functionality of live probiotic cells have led to the consideration of using non-viable microorganisms known as paraprobiotics. The study evaluated the effects of heat-inactivated cells of probiotic strain Shewanella putrefaciens Ppd11 on the intestinal microbiota and immune gene transcription in Solea senegalensis, and results showed differences in growth performance and modulation of the intestinal microbiota depending on the viability of the probiotics. Minor changes were detected in the intestinal immune response, with similar outcomes for both viable and inactivated probiotic cell supplemented diets compared to the control diet.
Article
Biochemistry & Molecular Biology
Jiseon Son, Hee-Jin Kim, Eui-Chul Hong, Hwan-Ku Kang
Summary: This study investigated the effects of heat stress and stocking density on the growth performance, antioxidant levels, and meat quality of broiler chickens. The results showed that high temperature and stocking density had negative impacts on the physiological status and meat quality of broilers. Lower stocking density alleviated oxidative stress induced by high temperatures and improved the antioxidant capacity and quality of breast meat in broilers.
Review
Fisheries
Jose-Pedro Canavate, Catalina Fernandez-Diaz
Summary: Salinity is a fundamental factor in microalgal aquaculture production, affecting the lipid composition and production of microalgae. Different microalgal species show varying responses to salinity, with hypersalinity having a greater impact on lipid profiles in cultured marine microalgae. Optimizing salinity levels can lead to more sustainable microalgal production.
REVIEWS IN AQUACULTURE
(2022)
Article
Multidisciplinary Sciences
Israel Guerrero-Cozar, Jessica Gomez-Garrido, Concha Berbel, Juan F. Martinez-Blanch, Tyler Alioto, M. Gonzalo Claros, Pierre-Alexandre Gagnaire, Manuel Manchado
Summary: The integration of physical and high-density genetic maps in the assembly of the Senegalese sole genome at a chromosome-level scaffold revealed differences in genomic recombination rates between sexes and identified important sex-associated genetic loci. Analysis of sex markers showed incomplete penetrance with males as the heterogametic sex. Comparison with other Pleuronectiformes genomes also revealed chromosomal rearrangements, including a lineage-specific Robertsonian fusion in S. senegalensis.
SCIENTIFIC REPORTS
(2021)
Article
Plant Sciences
Jose-Pedro Canavate, Catalina Fernandez-Diaz
Summary: Research on a estuarine Pavlovophyceae microalgae species showed specific changes in lipid class and fatty acids under high salinity, with phosphatidylglycerol playing a key role, while triacylglycerols increased only when cell growth ceased.
EUROPEAN JOURNAL OF PHYCOLOGY
(2022)
Article
Fisheries
Timothy Loher, Claude L. Dykstra, Allan C. Hicks, Ian J. Stewart, Nathan Wolf, Bradley P. Harris, Josep Planas
Summary: Estimates of discard mortality rates for Pacific Halibut captured and released back to the sea vary depending on the methodology used, but generally align with the currently applied rate. The study found that mortality of released fish occurred mainly after 40 days post-release, which differs from findings of previous captive studies where most mortality occurred within 20 days post-release.
NORTH AMERICAN JOURNAL OF FISHERIES MANAGEMENT
(2022)
Article
Green & Sustainable Science & Technology
Emilio Salas-Leiton, Ana Costa, Vanessa Neves, Joana Soares, Adriano Bordalo, Sergia Costa-Dias
Summary: This study investigates the current status and sustainability of fishing activities in the north-western region of Portugal. The results show that the fishing industry has demonstrated resilience in the face of economic challenges and that the next generation of regional fishers prioritize social and environmental standards. To further improve the sustainability of fisheries, a focus on technological advancements is recommended.
Article
Oncology
Aina Oliver-Caldes, Raquel Jimenez, Marta Espanol-Rego, Maria Teresa Cibeira, Valentin Ortiz-Maldonado, Luis F. Quintana, Paola Castillo, Francesca Guijarro, Natalia Tovar, Mercedes Montoro, Daniel Benitez-Ribas, Alex Bataller, E. Azucena Gonzalez-Navarro, Joan Cid, Miquel Lozano, Lorena Perez-Amill, Beatriz Martin-Antonio, Mari-Pau Mena, David F. Moreno, Luis Gerardo Rodriguez-Lobato, Josep Maria Campistol, Gonzalo Calvo, Joan Blade, Laura Rosinol, Manel Juan, Mariona Pascal, Alvaro Urbano-Ispizua, Carlos Fernandez de Larrea
Summary: Despite being incurable, multiple myeloma may benefit from CART therapy in patients with concomitant AL amyloidosis, even when the predominant symptoms are caused by the amyloidosis itself.
JOURNAL FOR IMMUNOTHERAPY OF CANCER
(2021)
Article
Fisheries
Jose-Pedro Canavate, Victoria Anguis-Climent, Catalina Fernandez-Diaz
Summary: This study evaluates the nutritional contribution of the green seaweed Ulva ohnoi in the diet of Senegalese sole. The results show that the seaweed is a good source of proteins and lipids for the fish, with high carbon assimilation rates in muscle and liver. The study also suggests that lipid extraction has minimal impact on the results.
Article
Agricultural Engineering
Giorgia Carnovale, Carmen Lama, Sonia Torres, Filipa Rosa, Lalia Mantecon, Svein Jarle Horn, Kari Skjanes, Carlos Infante
Summary: This study reveals that Tetraselmis chui is an efficient starch producer under nitrogen deprivation and shows a high recovery rate after nitrogen restitution. It also suggests that post-transcriptional regulatory mechanisms play a crucial role in nutrient stress response in T. chui.
BIORESOURCE TECHNOLOGY
(2022)
Article
Fisheries
Timothy Loher, Orion McCarthy, Lauri L. Sadorus, Lara M. Erikson, Anna Simeon, Daniel P. Drinan, Lorenz Hauser, Josep Planas, Ian J. Stewart
Summary: A study evaluated a marking program where sex-specific marks were applied to retained catch and validated using genetic techniques. The chosen marks, considered easy to apply, produced sex-ratio estimates equivalent to genetic results for 65% of sampled landings, though accuracy varied by vessel and region.
MARINE AND COASTAL FISHERIES
(2022)
Review
Oncology
Rosario Hervas-Salcedo, Beatriz Martin-Antonio
Summary: In this article, we discuss the interactions between multiple myeloma cells and non-hematological and hematological immune cells in the bone marrow, highlighting their effects on disease progression and treatment resistance. Non-hematological cells in the bone marrow can secrete molecules that accelerate disease progression, while these interactions compromise the activity of immune cells, leading to immune evasion and disease progression. Understanding these interactions can help in the development of improved treatments for multiple myeloma.
Article
Nutrition & Dietetics
Katherine Gil-Cardoso, Josep M. Del Bas, Antoni Caimari, Carmen Lama, Sonia Torres, Lalia Mantecon, Carlos Infante
Summary: TetraSOD (R), derived from the microalgae Tetraselmis chuii, is high in antioxidant enzymes and has the potential to enhance antioxidant and anti-inflammatory mechanisms to combat metabolic disturbances associated with Metabolic Syndrome (MetS). Research has shown that chronic supplementation with TetraSOD (R) can ameliorate abnormalities associated with MetS, including oxidative stress and inflammation, by promoting endogenous antioxidant defence mechanisms and regulating genes involved in antioxidant, anti-inflammatory, and immunomodulatory pathways in various tissues. Overall, TetraSOD (R) appears to be a promising therapeutic option for managing MetS.
Article
Multidisciplinary Sciences
Paula Rodriguez-Marquez, Maria E. Calleja-Cervantes, Guillermo Serrano, Aina Oliver-Caldes, Maria L. Palacios-Berraquero, Angel Martin-Mallo, Cristina Calvino, Marta Espanol-Rego, Candela Ceballos, Teresa Lozano, Patxi San Martin-Uriz, Amaia Vilas-Zornoza, Saray Rodriguez-Diaz, Rebeca Martinez-Turrillas, Patricia Jauregui, Diego Alignani, Maria C. Viguria, Margarita Redondo, Mariona Pascal, Beatriz Martin-Antonio, Manel Juan, Alvaro Urbano-Ispizua, Paula Rodriguez-Otero, Ana Alfonso-Pierola, Bruno Paiva, Juan J. Lasarte, Susana Inoges, Ascension Lopez-Diaz de Cerio, Jesus San-Miguel, Carlos Fernandez de Larrea, Mikel Hernaez, Juan R. Rodriguez-Madoz, Felipe Prosper
Summary: This study investigates the impact of CAR density on the functionality and clinical response of BCMA CAR T cells. It found that CAR T cells with high expression of the CAR construct have increased tonic signaling, up-regulation of exhaustion markers, and increased cytotoxicity in vitro but decreased bone marrow infiltration in vivo. Patients treated with CAR T cell products enriched in CAR(High) T cells show significantly worse clinical response in several hematological malignancies.
Article
Fisheries
Patricia Gayo, Concha Berbel, Evangelia Korozi, Ricardo Zerolo, Manuel Manchado
Summary: This study examines the use of EFDs analysis and ellipse fitting estimators to assess shape variation and genetic variance components in Senegalese sole. The results show that both symmetric and asymmetric components are related to body shape and fin features, with higher heritabilities for symmetric components. The findings can be applied to the design of genetic breeding programs for Senegalese sole.
Article
Fisheries
Adriana E. E. Sardi, Jose M. Moreira, Lisa Omingo, Xavier Cousin, Marie-Laure Begout, Manuel Manchado, Nina Marn
Summary: Research on recruitment variability has gained momentum due to climate change impacts. Knowledge about recruitment timings and success is important for commercial fish species. Predicting tools for determining the effect of temperature rise and food reduction on fish larvae are valuable for adapting fishing practices.
Article
Multidisciplinary Sciences
Liliana Anjos, Joao Estevao, Carlos Infante, Lalia Mantecon, Deborah Mary Power
Summary: This article presents a method for protein extraction from microalgae using bead milling and centrifugation, resulting in high-quality protein extracts. The method is cost-effective, efficient, scalable for industrial applications, and compatible with other processes. In addition, the article proposes the use of stabilizing agents for protein solubility and fractionation of low molecular weight proteins to enhance the value of the end product.