Article
Immunology
Mohamed Emam, Albert Caballero-Solares, Xi Xue, Navaneethaiyer Umasuthan, Barry Milligan, Richard G. Taylor, Rachel Balder, Matthew L. Rise
Summary: The study examined the effects of gill damage on Atlantic salmon by analyzing gill and liver tissues. The results showed that genes associated with wound healing and stress and immune responses were upregulated in moderately damaged gills and livers. Principal component analysis revealed that transcript levels in gills and livers could effectively differentiate different levels of gill damage. The gill damage-responsive biomarker genes and qPCR assays identified in this study will be valuable for future research on developing therapeutic diets for farmed salmon welfare improvement.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
Andre S. Bogevik, Elisabeth Ytteborg, Alexander Klevedal Madsen, Ann-Elise Olderbakk Jordal, Odd Andre Karlsen, Ivar Ronnestad
Summary: In this study, polyethylene (PE) microplastics were added to Atlantic cod feeds at 1%, either in their original form or spiked with PCB-126. After a 4-week period, cod fed spiked PE showed a higher concentration of PCB-126 in liver and muscle samples compared to control and fish ingesting virgin PE. The expression of hepatic cyp1a was higher in cod fed spiked PE, indicating an accumulation of PCB-126 in the liver. Moreover, both spiked PE and virgin PE had an effect on the skin, suggesting a reduced skin barrier in fish fed a diet containing PE.
MARINE POLLUTION BULLETIN
(2023)
Article
Cell Biology
Synne Arstad Bjornestad, Monica Hongro Solbakken, Kjetill S. Jakobsen, Sissel Jentoft, Oddmund Bakke, Cinzia Progida
Summary: Until recently, it was believed that MHC genes and their associated immune components had been conserved since their evolutionary emergence. However, sequencing of the Atlantic cod genome revealed a loss of MHC class II genes and an extreme expansion of MHC class I genes. These findings suggest a possible functional shift from MHC class II to MHC class I.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Fisheries
Guilan Di, Hui Li, Yanjing Zhao, Yan Lin, Di Lan, Xianghui Kong, Xinhua Chen
Summary: This study investigated the gene expression of the gills of Carassius auratus under hypoxia and Poly I:C exposure, and discovered differentially expressed genes and potential hypoxia biomarkers. The DEGs were mainly involved in glycolysis, oxidative phosphorylation, and immune-related pathways. The data generated in this study can provide valuable information for further research on immune response and strategies against hypoxia and Poly I:C in teleost fish.
AQUACULTURE REPORTS
(2022)
Article
Mathematics
Masaki Izumi, Hiroki Matui
Summary: This study proves several fundamental theorems used in the complete classification of poly-Z group actions on Kirchberg algebras, and classifies outer actions of poly-Z groups of Hirsch length not greater than three on unital Kirchberg algebras up to KK-trivial cocycle conjugacy as an application of these theorems.
INTERNATIONAL MATHEMATICS RESEARCH NOTICES
(2021)
Article
Surgery
Stephanie Cohen, Vanessa Cowan, Vinayak Rohan, Martha Pavlakis, Michael P. Curry, Joel T. Adler, Kassem Safa, Aaron Fleishman, Jessica Shenkel, James R. Rodrigue
Summary: Patient willingness to accept HCV-infected organs increased after education about HCV and transplantation benefits/risks. Factors associated with higher acceptance included history of intravenous drug use, older age, longer waiting time, trust in the transplant system, and awareness of DAAs. The main reasons for accepting HCV-infected organs were shorter waiting time, lower mortality and morbidity risk, effectiveness of DAAs, and quicker return to higher functional status.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Seoung-Woo Lee, Young-Jin Lee, Su-Min Baek, Kyung-Ku Kang, Tae-Un Kim, Jae-Hyuk Yim, Hee-Yeon Kim, Se-Hyeon Han, Seong-Kyoon Choi, Sang-Joon Park, Tae-Hwan Kim, Jin-Kyu Park
Summary: Vitamin C treatment plays an important role in nonalcoholic fatty liver disease by suppressing disease progression through decreased diet ingestion and increased water intake.
Article
Biochemistry & Molecular Biology
Anle Xu, Fei Han, Yuan Zhang, Tao Zhou, Tianxiang Gao
Summary: This study investigated the effects of poly (I:C) on Argyrosomus japonicus through comparative transcriptomic analyses. The results revealed that poly (I:C) significantly influenced gene expression in the liver and spleen, particularly in metabolism-related pathways and immune-related pathways.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Fisheries
Soumya Prasad Panda, Dhananjay Soren, Kausalya K. Nayak, Progyan Roy, B. K. Das
Summary: The study investigated the kinetics of Mx transcripts expression in the blood of Labeo catla inoculated with poly I: C for 14 days. Results showed an increase in Mx transcript levels after injection, indicating stimulation of an antiviral phase. The study suggests that investigating Mx expression could be a suitable indicator to assess protective action.
INDIAN JOURNAL OF FISHERIES
(2021)
Article
Environmental Sciences
Mona M. Taha, Eman M. Shahy, Heba Mahdy-Abdallah, Khadiga S. Ibrahim, Eman M. El Tahlawy
Summary: The study found that sewage workers exposed to cadmium had significantly higher levels of cadmium and cystatin-C in their blood and urine, as well as significant differences in genotype frequency distribution of ACE I/D and ACE G2350A genes, which were associated with hypertension and tubular injury. Additionally, the association of ACE DD polymorphism in conjunction with GG genotype of ACE2 in sewage workers was linked to hypertension and tubular injury.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Fisheries
Yuan Zhang, Xiaoyan Wang, Huilai Shi, Na Song, Fei Han, Xuejun Chai, Qi Liu, Yuebin Wang, Tianxiang Gao
Summary: This study conducted transcriptome analysis on the immune response of marbled rockfish to poly(I:C) stimulation, and found significant changes in immune-related biological processes and signaling pathways, enriching the theoretical basis for the development of immune adjuvants for this species.
Article
Chemistry, Analytical
Bing Wang, Xie-an Yu, Guo Yin, Jue Wang, Yibao Jin, Tiejie Wang
Summary: A novel and simple biosensor for the sensitive measurement of Cys C was successfully constructed based on graphene oxide and fluorophore-labelled aptamer, which can be used for early prediction of kidney injury through DNase I-aided recycling amplification strategy.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2021)
Article
Toxicology
Pal A. Olsvik, Sonnich Meier, Xiaokang Zhang, Anders Goksoyr, Odd Andre Karlsen, Fekadu Yadetie
Summary: This study aimed to compare the mode of action of environmentally relevant concentrations of mixtures of halogenated compounds in Atlantic cod in North Sea and North Atlantic coastal areas. The results showed that halogenated compounds activated the unfolded protein response (UPR) pathway in cod. There was no additive effect observed when cod were exposed to mixtures of all three compound groups.
JOURNAL OF APPLIED TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Wen-Qiang Wu, Xin Zhang, Di Bai, Song-Wang Shan, Li-Jun Guo
Summary: This study comprehensively investigated the mechanisms of interaction between I-motifs and PCBPs, revealing how heterogeneous nuclear ribonucleoprotein K (hnRNP K) unfolds the I-motif structure in the c-MYC oncogene promoter. Furthermore, the role of KH domains in this process was also discovered. This research enhances our understanding of the interactions between I-motifs and PCBPs and may provide insights for drug development.
JOURNAL OF BIOLOGICAL CHEMISTRY
(2022)
Article
Medicine, General & Internal
Yuwei Yang, Bin Ge, Yan Liu, Jiafu Feng
Summary: This study investigates the roles of NGAL, CysC, and sCr in diagnosing AKI secondary to liver cirrhosis. Results suggest that NGAL may outperform sCr and CysC, with uNGAL being a more reliable indicator for diagnosing AKI.
Article
Fisheries
Manoharmayum Shaya Devi, Gunjan Karnatak, Basanta Kumar Das, Asit Kumar Bera, Nilemesh Das, Chayna Jana, Mishal Puthiyottil, Tasso Tayung, Bijay Kumar Behera, Uttam Kumar Sarkar, Yusuf Ali
Summary: This study reports the occurrence of metacercariae of Isoparorchis hypselobagri in cultured food fish Ompok bimaculatus in India. Identification was done through morphology and molecular techniques. The infection patterns were recorded and the influence of host size, season, and water quality on infection rate was tested. The presence of parasites poses a threat to fish production and consumer acceptance, and control of snail vectors is important for prevention of parasitic diseases in cage culture.
Article
Biophysics
Dhruba Jyoti Sarkar, Bijay Kumar Behera, Pranaya Kumar Parida, Vijay Kumar Aralappanavar, Shirsak Mondal, Jyotsna Dei, Basanta Kumar Das, Subhankar Mukherjee, Souvik Pal, Pabudi Weerathunge, Rajesh Ramanathan, Vipul Bansal
Summary: This article discusses the application of aptasensors in detecting contaminants in seafood products, emphasizing their use as a powerful and robust analytical tool. Aptamers have high specificity in recognizing various contaminants, making them effective molecular recognition elements for diagnostic and biosensing tools.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Environmental Sciences
Bijay Kumar Behera, Biswanath Patra, Hirak Jyoti Chakraborty, Ajaya Kumar Rout, Sangita Dixit, Anil Rai, Basanta Kumar Das, Trilochan Mohapatra
Summary: Bacteriophages are important in killing harmful microbes in polluted sites, and they are abundantly present in the Ganga river. The study of bacteriophage diversity and abundance in polluted and non-polluted sites is significant for understanding their role in maintaining water sterility and healing power.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
Hemanta Chowdhury, Asit Kumar Bera, Subhashree Subhasmita Raut, Ramesh Chandra Malick, Himanshu Sekhar Swain, Ajoy Saha, Basanta Kumar Das
Summary: Diseases caused by antibiotic-resistant Aeromonads are common and troublesome in aquaculture. In this study, the antibacterial efficacy of Cymbopogon flexuosus essential oil was investigated against OTC-resistant and sensitive strains of Aeromonas hydrophila. The oil exhibited dose-dependent growth inhibition of the bacteria and showed effectiveness against OTC-resistant isolates. Molecular docking experiments revealed that some components of the oil strongly bonded with DNA gyrase-B, inhibiting its efficacy. The identified phytochemicals had favorable physicochemical and pharmacokinetic properties and satisfied the rule of five (Ro5).
CHEMISTRY & BIODIVERSITY
(2023)
Article
Biochemistry & Molecular Biology
Soumya Prasad Panda, Pragyan Roy, Dhananjay Soren, Deepak Ranjan Sahoo, Budheswar Dehury, Ajaya Kumar Rout, Bijay Kumar Behera, Basanta Kumar Das
Summary: This study investigates the characterization and function of the Mx gene in Labeo catla induced by double-stranded RNA. Molecular modeling and molecular dynamics simulations were used to understand the structure and GTP recognition mode of the GTPase domain in Mx protein. The results show that the expression of the Mx gene is able to inhibit viral infection mediated by double-stranded RNA.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Green & Sustainable Science & Technology
Simanku Borah, Basanta Kumar Das, Birendra Kumar Bhattacharjya, Gunjan Karnatak, Anil Kumar Yadav, Arun Pandit, Pranaya Kumar Parida, Aparna Roy, Amiya Kumar Sahoo, Bijay Kumar Behera, Archan Kanti Das, Nilmani Rabha, Priyanka Priyadarshini
Summary: Labeo bata fry were reared in HDPE pens at different stocking densities to evaluate their growth, survival, feed utilization efficiency, and economics. The results showed that increasing stocking density led to a decrease in weight gain and specific growth rate, but an increase in net and gross yields. The study highlights the importance of species diversification in pen enclosures, income enhancement for small-scale wetland fishers, and sustainable ecosystem-based floodplain wetland fisheries management.
Article
Microbiology
Bijay Kumar Behera, Satya Narayan Parida, Vikash Kumar, Himanshu Sekhar Swain, Pranaya Kumar Parida, Kampan Bisai, Souvik Dhar, Basanta Kumar Das
Summary: This study investigated a case of severe mortality in farmed Labeo rohita and identified the causative agent as Aeromonas veronii. The isolated strain showed resistance to ampicillin and dicloxacillin, but susceptibility to 22 other antibiotics. It was also found that A. veronii induced stress and immune responses in L. rohita. The negative effects of the pathogen on fish health and high mortality rate highlight the need for A. veronii management.
Article
Fisheries
Soumya Prasad Panda, Dhananjay Soren, Pragyan Roy, Debasmita Mohanty, Dharmendra Kumar Meena, Amiya Kumar Sahoo, Basanta Kumar Das
Summary: This study identified the expression of Mx gene in different organs of catla fish and found that the spleen had the highest expression. The expression of Mx gene was significantly upregulated in all tissues regardless of the type of infection or saponin administration. The study also revealed the potential of microbial infection and saponin treatment as immune-stimulatory agents.
AQUACULTURE INTERNATIONAL
(2023)
Article
Marine & Freshwater Biology
Shreya Roy, Dhruba Jyoti Sarkar, Nabanita Chakraborty, Kausik Mondal, Basanta Kumar Das
Summary: Microplastic pollution is a global issue that affects terrestrial and marine ecosystems. This study found that the accumulation of microplastics in freshwater snails can lead to changes in nonenzymatic antioxidant levels and AChE activity, which could have negative impacts on the ecosystem.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Dhruba Jyoti Sarkar, Soma Das Sarkar, V. Santhana Kumar, Thangjam Nirupada Chanu, Tanushree Banerjee, Lokenath Chakraborty, Manisha Bhor, Subir Kumar Nag, Srikanta Samanta, Basanta Kumar Das
Summary: The study evaluates the effect of natural floating island (FADs) on the distribution of heavy metals in a freshwater wetland. The results show that FADs have lower concentrations of heavy metals, leading to reduced pollution indices in surface water and fish species.
ENVIRONMENTAL POLLUTION
(2023)
Article
Chemistry, Multidisciplinary
Dhruba Jyoti Sarkar, Saswata Goswami, Swarupananda Sahu, Bijay Kumar Behera, Pranaya Parida, Shyamal Chandra Sukla Das, Basanta Kumar Das, Partha Sarkar, Debabrata Pradhan, Subhankar Mukherjee, Souvik Pal, Vipul Bansal
Summary: In this study, polyvinyl alcohol (PVA) capped AgNPs (AgNPs@PVA) were used as a nanocarrier to fabricate an acetylcholinesterase (AChE) biosensor for the detection of organophosphate (OP) pesticides. The AChE enzyme was immobilized onto a drop casted AgNPs@PVA layer on a glassy carbon electrode (GCE) to fabricate the electrochemical biosensor. The biosensor measured the peak current at 0.6 V generated by the AChE-mediated hydrolysis of acetylthiocholine (ATCl) to thiocholine and its subsequent oxidation to dimer through differential pulse voltammetry (DPV). A model OP pesticide, malathion, was used to hinder the AChE hydrolysis activity of the sensor probe, and the inhibition effect was found to be proportional to the concentration of malathion. The fabricated biosensor showed linearity in the range of 0.01 to 1 ng/mL of malathion at optimal conditions, with a detection limit (LOD) of 2.6 pg/mL. The AChE biosensor exhibited good selectivity for OP pesticides and demonstrated efficiency in real sample analysis.
Article
Environmental Sciences
Mitesh H. Ramteke, Himanshu S. Swain, Aurobinda Upadhyay, Vikas Kumar, Suman Kumari, Basanta K. Das
Summary: This study investigated the effects of different stocking densities on the growth performance of Pangasianodon hypophthalmus. The results showed that stocking densities in the range of 20 to 40 m(-3) resulted in the highest final weight, relative growth rate, and specific growth rate. The feed conversion ratio was significantly lower at lower densities. Muscle quality also improved at lower densities, leading to reduced drip loss and frozen leakage rate. Elevated levels of SGOT, SGPT, glucose, and cortisol were detrimental to fish growth. The stocking density of 30 m(-3) had the highest benefit-cost ratio and return on investment.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Agriculture, Dairy & Animal Science
V. Kumar, S. N. Parida, S. Roy, S. Dhar, K. Bisai, B. K. Behera, B. K. Das
Summary: The aquatic food production system raises aquatic organisms for human consumption, and the development of a cost-efficient production method is a significant challenge for the future. Recent advancements in biotechnological tools and approaches have provided new opportunities in optimizing processes and manufacturing genetically modified fish. These tools are also transferable to other aquatic species production systems, leading to promising results in the industry.
ANNALS OF ANIMAL SCIENCE
(2023)
Article
Environmental Sciences
Nitish Kumar Tiwari, Trupti Rani Mohanty, Subhadeep Das Gupta, Shreya Roy, Himanshu Sekhar Swain, Raju Baitha, Mitesh Hiradas Ramteke, Basanta Kumar Das
Summary: A study was conducted to assess the hematological and biochemical responses of fishes to ecological alterations in the middle and lower stretches of river Ganga. Water pollution index, water quality index, and pollution index were calculated based on various water quality parameters. The results showed significant correlations between water quality indices and several hematological and biochemical parameters. The study emphasized the importance of monitoring the hemato-biochemical responses of fishes to ecological alterations.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Engineering, Environmental
Sourav Kundu, Ayan Biswas, Archisman Ray, Shreya Roy, Subhadeep Das Gupta, Mitesh Hiradas Ramteke, Vikas Kumar, Basanta Kumar Das
Summary: This study, the first of its kind, examines the impact of BPA pollution on aquatic ecosystems and fisheries and finds that Hilsa shad is contaminated with BPA and poses health hazards to human beings.
JOURNAL OF HAZARDOUS MATERIALS
(2024)
