Targeting of MyD88 Homodimerization by Novel Synthetic Inhibitor TJ-M2010-5 in Preventing Colitis-Associated Colorectal Cancer

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Molecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coli

(2013) G. A. Snyder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88 and its divergent toll in carcinogenesis

(2013) Rosalba Salcedo et al.   TRENDS IN IMMUNOLOGY

Signaling via MYD88 in the pancreatic tumor microenvironment

(2013) Constantinos P. Zambirinis et al.   OncoImmunology

The inflammatory network in the gastrointestinal tumor microenvironment: lessons from mouse models

(2012) Hiroko Oshima et al.   JOURNAL OF GASTROENTEROLOGY

Therapeutic Inhibition of Pro-Inflammatory Signaling and Toxicity to Staphylococcal Enterotoxin B by a Synthetic Dimeric BB-Loop Mimetic of MyD88

(2012) Teri L. Kissner et al.   PLoS One

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11bhighGr1low macrophages

(2011) Gabriela Schiechl et al.   JOURNAL OF CLINICAL INVESTIGATION

Absence of MyD88 Results in Enhanced TLR3-Dependent Phosphorylation of IRF3 and Increased IFN-  and RANTES Production

(2011) J. Siednienko et al.   JOURNAL OF IMMUNOLOGY

Remote Control of Intestinal Tumorigenesis by Innate Immunity

(2010) T. Secher et al.   CANCER RESEARCH

TLR4-mediated skin carcinogenesis is dependent on immune and radioresistant cells

(2010) Deepak Mittal et al.   EMBO JOURNAL

Inflammation and Colon Cancer

(2010) Janoš Terzić et al.   GASTROENTEROLOGY

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18

(2010) Rosalba Salcedo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence

(2010) Manisha Yadav et al.   PLoS Pathogens

The TIR/BB-loop mimetic AS-1 protects the myocardium from ischaemia/reperfusion injury

(2009) Z. Cao et al.   CARDIOVASCULAR RESEARCH

Molecular Mimicry in Innate Immunity

(2009) Siew Leong Chan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated macrophages in the tumour microenvironment-dancing to the tune of TLR and NF-κB

(2009) Simon Hallam et al.   JOURNAL OF PATHOLOGY

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

(2009) H. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

(2008) Christine Cirl et al.   NATURE MEDICINE

Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

(2008) J. B. Swann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA