期刊
FERTILITY AND STERILITY
卷 102, 期 5, 页码 -出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.fertnstert.2014.07.709
关键词
Endometriosis; standardization; harmonization; phenotyping; laparoscopy; EPHect SSF
资金
- Bayer Healthcare
- Roche Diagnostics
- Auxogyn
- Ferring Pharmaceuticals
- Merck Serono Merck
- Besins
- Pharmaplex
- Astellas
- World Endometriosis Research Foundation through grants from AbbVie Inc
- Bayer Pharma AG
- Roche Diagnostics International Ltd.
- Wellcome Trust [WT085235/Z/08/Z]
- J. Willard and Alice S. Marriott Foundation contribution
- National Institutes of Health (NIH) Eunice Kennedy Shriver National Institute of Child Health and Human Development grant [HD57210]
- Intramural Program of the National Institutes of Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development [HD008769-11]
- Oxford Partnership Comprehensive Biomedical Research Centre
- Department of Health's National Institute for Health Research Biomedical Research Centres Scheme
- Puerto Rico Science and Technology Trust [2013-000032]
- MRC [MR/K011480/1]
- Ernst Schering Foundation
- Elsa Neumann Stipendium des Landes Berlin
- Endometriosis Association
- Eunice Kennedy Shriver National Institute of Child Health and Human Development Specialized Cooperative Centers Program in Reproduction and Infertility Research [U54HD 055764]
- MRC [MR/K011480/1, G0601458] Funding Source: UKRI
- Medical Research Council [G0601458, MR/K011480/1] Funding Source: researchfish
- National Institute for Health Research [CL-2008-13-002] Funding Source: researchfish
Objective: To standardize the recording of surgical phenotypic information on endometriosis and related sample collections obtained at laparoscopy, allowing large-scale collaborative research into the condition. Design: An international collaboration involving 34 clinical/academic centers and three industry collaborators from 16 countries. Setting: Two workshops were conducted in 2013, bringing together 54 clinical, academic, and industry leaders in endometriosis research and management worldwide. Patient(s): None. Intervention(s): A postsurgical scoring sheet containing general and gynecological patient and procedural information, extent of disease, the location and type of endometriotic lesion, and any other findings was developed during several rounds of review. Comments and any systematic surgical data collection tools used in the reviewers' centers were incorporated. Main Outcome Measure(s): The development of a standard recommended (SSF) and minimum required (MSF) form to collect data on the surgical phenotype of endometriosis. Result(s): SSF and MSF include detailed descriptions of lesions, modes of procedures and sample collection, comorbidities, and potential residual disease at the end of surgery, along with previously published instruments such as the revised American Society for Reproductive Medicine and Endometriosis Fertility Index classification tools for comparison and validation. Conclusion(s): This is the first multicenter, international collaboration between academic centers and industry addressing standardization of phenotypic data collection for a specific disease. The Endometriosis Phenome and Biobanking Harmonisation Project SSF and MSF are essential tools to increase our understanding of the pathogenesis of endometriosis by allowing large-scale collaborative research into the condition. (C) 2014 by American Society for Reproductive Medicine.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据