Article
Medicine, General & Internal
Sebastian Harth, Fritz C. Roller, Felix Zeppernick, Ivo Meinhold-Heerlein, Gabriele A. Krombach
Summary: In this retrospective study, MRI was found to have high diagnostic accuracy for pelvic deep infiltrating endometriosis (DIE), especially when strict diagnostic criteria were applied. This suggests that MRI can serve as a method to confirm clinically suspected DIE.
Review
Medicine, General & Internal
Stefano Guerriero, Silvia Ajossa, Mariachiara Pagliuca, Antonietta Borzacchelli, Fabio Deiala, Serena Springer, Monica Pilloni, Valeria Taccori, Maria Angela Pascual, Betlem Graupera, Luca Saba, Juan Luis Alcazar
Summary: With the development of standardized diagnostic protocols and improved technology, the use of imaging techniques for the diagnosis of pelvic endometriosis has become a reality. Transvaginal ultrasound and magnetic resonance imaging are now the two accurate imaging techniques that can identify the majority of endometriosis phenotypes.
Article
Biochemistry & Molecular Biology
Alexandra Irma Gabriela Bausic, Daniela Roxana Matasariu, Andrei Manu, Elvira Bratila
Summary: This study assessed the diagnostic accuracy of transvaginal sonography (TVS) and pelvic magnetic resonance imaging (MRI) for deep infiltrated endometriosis (DIE). The results showed that TVS is a reliable tool for diagnosing ovarian endometriomas, while MRI is generally more effective in evaluating the severity of endometriosis. However, TVS demonstrates comparable diagnostic accuracy to MRI in diagnosing DIE.
Review
Radiology, Nuclear Medicine & Medical Imaging
Filomenamila Lorusso, Marco Scioscia, Dino Rubini, Amato Antonio Stabile Ianora, Doriana Scardigno, Carla Leuci, Michele De Ceglie, Angela Sardaro, Nicola Lucarelli, Arnaldo Scardapane
Summary: Endometriosis is a chronic disease affecting women's reproductive health, with diagnosis now relying on non-invasive approaches such as clinical history, therapy response, and imaging. Trans-vaginal ultrasound and pelvic MRI are important tools for recognizing lesions, but their accuracy is operator-dependent.
INSIGHTS INTO IMAGING
(2021)
Review
Acoustics
B. Gerges, W. Li, M. Leonardi, B. W. Mol, G. Condous
Summary: This study reviewed the accuracy of different imaging modalities for detecting rectosigmoid deep endometriosis in women with clinical suspicion of endometriosis. The results showed that transvaginal sonography (TVS) had slightly better sensitivity than magnetic resonance imaging (MRI), while rectal endoscopic sonography (RES) had even higher sensitivity than both.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Medicine, General & Internal
Elena P. P. Khashchenko, Elena V. V. Uvarova, Timur Kh. Fatkhudinov, Vladimir D. D. Chuprynin, Aleksandra V. V. Asaturova, Elena A. A. Kulabukhova, Mikhail Yu. Vysokikh, Elvina Z. Z. Allakhverdieva, Maria N. N. Alekseeva, Leila V. V. Adamyan, Gennady T. T. Sukhikh
Summary: The aim of this study was to improve early diagnosis of endometriosis in adolescents by conducting clinical, imaging, laparoscopic, and histological analyses. Adolescents with endometriosis exhibited heredity, persistent dysmenorrhea, decreased daily activity, and gastrointestinal symptoms. Ultrasound and MRI could detect endometriosis, and certain MRI signs were associated with the disease. Persistent dysmenorrhea and MRI parameters predicted the laparoscopic confirmation of endometriosis, justifying early surgical diagnostics.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Alexandra Bausic, Ciprian Coroleuca, Catalin Coroleuca, Diana Comandasu, Roxana Matasariu, Andrei Manu, Francesca Frincu, Claudia Mehedintu, Elvira Bratila
Summary: Endometriosis is a common gynecological condition that can cause various symptoms in women of reproductive age. Accurate diagnosis is essential for effective treatment, and different diagnostic methods should be chosen based on the type of endometriosis.
Article
Biophysics
Nian Wang, Surendra Maharjan, Andy P. Tsai, Peter B. Lin, Yi Qi, Abigail Wallace, Megan Jewett, Fang Liu, Gary E. Landreth, Adrian L. Oblak
Summary: High-resolution MRI provides unique image contrasts to probe tissue microstructure, but validation with histology is essential due to differences in spatial resolution and image contrast. To validate MRI metrics, whole mouse brain imaging was performed at high resolution using the Allen Mouse Brain Common Coordinate Framework (CCFv3). Comparison between MRI metrics and histology revealed regional and metric-dependent correlations. Integrating different imaging modalities in a common space improves our understanding of brain complexity at different scales.
NMR IN BIOMEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Zahra Raisi-Estabragh, Jackie Cooper, Celeste McCracken, Emma J. Crosbie, Fiona M. Walter, Charlotte H. Manisty, John Robson, Mamas A. Mamas, Nicholas C. Harvey, Stefan Neubauer, Steffen E. Petersen
Summary: This study evaluates incident cardiovascular outcomes and imaging phenotypes in UK Biobank participants with previous cancer. It found that cancer history is associated with an increased risk of cardiovascular diseases and adverse cardiac remodeling, independent of shared vascular risk factors.
Review
Radiology, Nuclear Medicine & Medical Imaging
Ella Fokkinga, Juan A. Hernandez-Tamames, Andrada Ianus, Markus Nilsson, Chantal M. W. Tax, Raquel Perez-Lopez, Francesco Grussu
Summary: This article reviews the latest developments in diffusion-weighted magnetic resonance imaging (DW-MRI) in the field of oncology, analyzing its value compared to histology measurements. The reviewed techniques provide histologically meaningful indices of cancer microstructure and have sensitivity to microscopic pathological processes.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Obstetrics & Gynecology
Marc Bazot, Edith Kermarrec, Sofiane Bendifallah, Emile Darai
Summary: Endometriosis is a common gynecological condition affecting women of reproductive age, with gastrointestinal involvement mainly in the rectosigmoid colon. MRI is recommended for diagnosis and evaluation of severe forms of deep endometriosis, including intestinal endometriosis.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2021)
Article
Acoustics
Sang Won Choi, Sarah Duclos, Sandra Camelo-Piragua, Neeraj Chaudhary, Jonathan Sukovich, Timothy Hall, Aditya Pandey, Zhen Xu
Summary: The objective of this study was to investigate and correlate the MRI characteristics with histological analysis after histotripsy treatment of brain tumors. The results showed that T2 and T2* sequences accurately correlated with the histotripsy treatment zone. T1-Gd sequence revealed the state of the blood-brain barrier arising from the tumor or histotripsy ablation. The study concluded that these results provide a library of radiological features on MRI sequences correlated to histology for non-invasive evaluation of histotripsy treatment effects.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Andre Obenaus, Eli Kinney-Lang, Amandine Jullienne, Elizabeth Haddad, Kara M. M. Wendel, A. Duke Shereen, Ana Solodkin, Jeffrey F. F. Dunn, Tallie Z. Z. Baram
Summary: Previous neuroimaging techniques have struggled to accurately delineate the boundaries of the amygdaloid complex, specifically the basolateral nucleus (BLA), due to poor contrast. This study presents a novel diffusion tensor imaging (DTI) approach that enhances contrast, allowing for precise measurement and validation of BLA volumes using histological and cellular-identity techniques. The principles utilized in this study can be applied to other brain regions and various species.
Article
Obstetrics & Gynecology
Philippe R. Koninckx, Anastasia Ussia, Leila Adamyan, Muna Tahlak, Jorg Keckstein, Arnaud Wattiez, Dan C. Martin
Summary: Endometriosis was previously considered a single disease, but is now understood to encompass various pathologies. Most datasets do not take into account the severity of the condition, leading to challenges in recognizing subtle lesions.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2021)
Article
Rheumatology
Han Cen, Qingran Yan, Tao Meng, Zhongshan Chen, Jimin Zhu, Yuanyuan Wang, Guangfeng Ruan, Tian Wang, Weiyu Han, David Hunter, Changhai Ding
Summary: This study aimed to determine the association of quantitative infrapatellar fat pad (IPFP) signal intensity alteration with knee osteoarthritis (OA) progression. Through quantitative measurements taken at baseline, 12 months, and 24 months, the associations between IPFP signal intensity measures and knee OA progression over 48 months were evaluated. The findings suggest that short-term alterations in quantitative IPFP signal intensity measures are associated with long-term knee OA progression, making them potential biomarkers for intervention efficacy in knee OA.
Article
Mathematical & Computational Biology
Soutik Ghosal, Zhen Chen
Summary: The study used longitudinal ultrasound examination data to estimate diagnostic accuracy parameters for predicting large fetuses at birth. The integration of placement value and Bayesian regression model proved to be more effective in simulations and application to real data. The diagnostic accuracy of estimated fetal weight was found to improve by about 65% from week 17 to 37 of gestation according to the Scandinavian Study data.
STATISTICS IN BIOSCIENCES
(2022)
Article
Obstetrics & Gynecology
Maged M. Costantine, Madeline Murguia Rice, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, Alan T. N. Tita, John M. Thorp, Edward K. Chien, Alan M. Peaceman, Sean C. Blackwell
Summary: This study aims to evaluate whether the values and shape of the glucose curve during an oral glucose tolerance test (OGTT) in pregnancy can identify women at risk of developing hypertension later in life. The results suggest that the 2-hour OGTT value was positively associated with the primary outcome, while the 3-hour OGTT value was negatively associated. Furthermore, a monophasic OGTT response was associated with an increased risk of hypertension.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Editorial Material
Medicine, General & Internal
Germaine M. Buck Louis
ANNALS OF INTERNAL MEDICINE
(2022)
Review
Integrative & Complementary Medicine
Jiao Ju-ying, Cheng Chien-snan, Cao Zhang-qi, Chen Lian-Yu, Chen Zhen
Summary: Cancer, a deadly disease, has limited therapeutic options. Complementary and alternative medicine, particularly Chinese medicine, has been widely used in cancer management. However, there is a lack of understanding about the molecular characteristics of dampness-heat syndrome and a standardized animal model for studying this core syndrome in vivo.
CHINESE JOURNAL OF INTEGRATIVE MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ashley N. Battarbee, Lisa Mele, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, John M. Thorp, Edward K. Chien, George Saade, Beth A. Plunkett, Sean C. Blackwell
Summary: The objective of this study was to evaluate the association between mild gestational diabetes mellitus (GDM) and obesity with metabolic and cardiovascular markers 5 to 10 years after pregnancy. The results showed that prior GDM and obesity were associated with increased insulin resistance but no consistent cardiovascular dysfunction or alterations in insulin secretion.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Veterinary Sciences
Philibert Dougnon, Victorien Dougnon, Boris Legba, Kafayath Fabiyi, Arnaud Soha, Hornel Koudokpon, Kevin Sintondji, Esther Deguenon, Gildas Hounmanou, Carlos Quenum, Taeratou Aminou, Richard Lokossou, Innocent Togla, Cyrille Boko, Bruno Djossa, Francoise Assogba-komlan, Lamine Baba-moussa
Summary: This study assessed the presence of pathogenic bacteria in imported day-old chicks from Belgium to Benin. The results showed that Escherichia coli, Enterococcus spp., and coagulase-negative staphylococci were the most common bacteria identified. The Escherichia coli strains exhibited high resistance rates against ciprofloxacin and trimethoprim + sulfamethoxazole. Immediate detection of resistant bacteria in imported chicks is necessary to prevent their dissemination.
BMC VETERINARY RESEARCH
(2023)
Review
Peripheral Vascular Disease
Karen C. Schliep, Hailey Mclean, Bin Yan, Fares Qeadan, Lauren H. Theilen, Adam de Havenon, Jennifer J. Majersik, Truls Ostbye, Surendra Sharma, Michael W. Varner
Summary: Previous meta-analyses have shown that women with a history of hypertensive disorders of pregnancy (HDP) have a 2- to 4-fold increased risk of later cardiovascular disease. This study aims to summarize the evidence for the impact of HDP on dementia and explore the unique associations between HDP and dementia subtypes.
Article
Mathematical & Computational Biology
Abhisek Saha, Rajeshwari Sundaram
Summary: Understanding the impact of mixtures of environmental toxicants on time-to-pregnancy is important. We propose a discrete frailty modeling framework to address the statistical challenges associated with assessing chemical mixtures. Analysis of data from the LIFE study reveals that older females, female exposure to cotinine (smoking), and DDT are associated with delayed pregnancy.
STATISTICS IN MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ashley Battarbee, Lisa B. Mele, Mark W. Landon, Michael M. Varner, Brian M. Casey, Uma J. Reddy, Ronald J. Wapner, Dwight M. Rouse, John K. Thorp, Edward Chien, George M. Saade, Alan C. Peaceman, Sean Blackwell
Summary: This study aimed to measure the association between hypertensive disorders of pregnancy (HDP) and long-term maternal metabolic and cardiovascular biomarkers. The results showed no association between HDP and metabolic or cardiovascular biomarkers, but patients with preeclampsia may have lower levels of oxidative stress/cardiac ischemia.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Maged M. M. Costantine, Alan T. N. Tita, Lisa Mele, Brian M. M. Casey, Alan M. M. Peaceman, Michael W. W. Varner, Uma M. M. Reddy, Ronald J. J. Wapner, John M. M. Thorp, George R. R. Saade, Dwight J. J. Rouse, Baha Sibai, Brian M. M. Mercer, Steve N. N. Caritis
Summary: The study aimed to assess the association between being small for gestational age (SGA), large for gestational age (LGA), or having a small or large head circumference (HC) at birth and adverse neurodevelopmental outcomes. The results showed that SGA at birth was associated with a decrease in child IQ and higher odds of child IQ < 85 at 5 years of age, while LGA at birth was not associated with adverse outcomes. Using a fetal growth standard did not improve the detection of newborns at risk of adverse neurodevelopment.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Michael W. Varner, Elizabeth A. Thom, C. Michael Cotten, Susan R. Hintz, Grier P. Page, Dwight J. Rouse, Brian M. Mercer, Maged M. Costantine, Yoram Sorokin, John M. Thorp Jr, Susan M. Ramin, Marshall W. Carpenter, Mary J. O'Sullivan, Alan M. Peaceman, George R. Saade, Donald J. Dudley, Steve N. Caritis
Summary: This study found genetic variants associated with adverse neurodevelopmental outcomes in extremely low birth weight infants, including a variant in the SERPINE1 gene that is associated with cerebral palsy or death.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Nutrition & Dietetics
Ling-Jun Li, Ruochen Du, Marion Ouidir, Ruijin Lu, Zhen Chen, Natalie L. Weir, Michael Y. Tsai, Paul S. Albert, Cuilin Zhang
Summary: Saturated fatty acids (SFAs) during pregnancy have an impact on metabolic programming and fetal growth. In this study, plasma phospholipid SFAs were measured in early pregnancy and fetal growth was monitored. It was found that even-chain and very long even-chain SFAs were negatively associated, while odd-chain SFAs were positively associated with fetal weight and size. Pentadecanoic acid (15:0) in the highest tertile showed a greater fetal weight and size compared to the lowest tertile. These findings suggest the potential use of an alternative high-fat diet rich in odd-chain SFAs for optimal fetal growth.
Article
Mathematical & Computational Biology
Abhisek Saha, Ling Ma, Animikh Biswas, Rajeshwari Sundaram
Summary: This article proposes a shared parameter joint model to investigate the association between cyclical longitudinal processes and discrete survival time. The results show that the geometric features of the longitudinal process, such as curvature and peak location and height, are associated with survival time.
STATISTICS IN BIOSCIENCES
(2023)
Article
Obstetrics & Gynecology
Ann M. Bruno, Amanda A. Allshouse, Ashley E. Benson, Christian Con Yost, Torri D. Metz, Michael W. Varner, Robert M. Silver, D. Ware Branch
Summary: Thrombotic markers in pregnant individuals are not affected by SARS-CoV-2 infection, but a high rate of LAC positivity is common. The severity of the disease is not associated with D-dimer levels and LAC positivity.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Susanna D. Mitro, Rajeshwari Sundaram, Yan Qiao, Jessica L. Gleason, Edwina Yeung, Stefanie N. Hinkle, Pauline Mendola, James L. Mills, Sonia M. Grandi, Sunni L. Mumford, Enrique F. Schisterman, Cuilin Zhang, Katherine L. Grantz
Summary: Multifetal gestation is not associated with long-term maternal mortality, but may be associated with a lower risk of premature mortality.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2023)